scholarly journals Erysipelothrix rhusiopathiae infection by geese to human transmission

2021 ◽  
Vol 14 (5) ◽  
pp. e240073
Author(s):  
Simone Martina Meier ◽  
Jan Kottwitz ◽  
Dagmar I Keller ◽  
Sarah Albini
Keyword(s):  
Case Report ◽  
Case History ◽  
Susceptibility Testing ◽  
Interdisciplinary Approach ◽  
Infectious Agent ◽  
Antibiotic Susceptibility Testing ◽  
Erysipelothrix Rhusiopathiae ◽  
Zoonotic Infection ◽  
Zoonotic Infections

Erysipelothrix rhusiopathiae transmission to human is often occupation-related, but in most cases, a detailed case history is missing. This case report is based on an interdisciplinary approach and includes a thorough medical record. A 58-year-old laboratory technician working on geese necropsy cut open her glove at a rib fragment of a goose and subsequently noticed a slowly progressive, reddish skin alteration in the particular region of the hand. Bacteriological investigations on the geese revealed septicaemia due to E. rhusiopathiae and therefore substantiated the diagnosis of the patient. The infectious agent could not be cultured from the patient; however, antibiotic susceptibility testing was performed using the goose isolate. An entire follow-up until full recovery of the patient was conducted. Zoonotic infections possibly have a significant impact on certain occupations. This case report analyses a rare but important zoonotic infection to create awareness of this in physicians caring for human patients.

scholarly journals Reduced Clinical Efficacy of Pazufloxacin against Gonorrhea Due to High Prevalence of Quinolone-Resistant Isolates with the GyrA Mutation

1998 ◽  
Vol 42 (3) ◽  
pp. 579-582 ◽  
Author(s):  
Masatoshi Tanaka ◽  
Tetsuro Matsumoto ◽  
Misao Sakumoto ◽  
Koichi Takahashi ◽  
Takeshi Saika ◽  
...  
Keyword(s):  
Susceptibility Testing ◽  
Oral Dosage ◽  
Antibiotic Susceptibility Testing ◽  
Wild Type ◽  
Gonococcal Urethritis ◽  
Negative Culture ◽  
High Prevalence ◽  
The Mean ◽  
Gyra Mutation

ABSTRACT Forty-two men with gonococcal urethritis were treated with an oral dosage of 200 mg of pazufloxacin, a new fluoroquinolone, three times daily for 3 days. Only 28 of the 42 men (66.7%) had negative culture results for Neisseria gonorrhoeae during follow-up. Of the 42 isolates, 41 could be recultured for antibiotic susceptibility testing and DNA sequencing. In 26 of the 41 isolates (63.4%), GyrA mutations with or without ParC mutations were identified. Among the 26 isolates, 23 contained a single GyrA mutation, 1 contained two GyrA mutations, and 2 contained three mutations including double GyrA and single ParC mutations. A single Ser-91-to-Phe mutation, which was detected in 14 of the 26 isolates, was the most common GyrA mutation, followed by an Ala-75 to Ser mutation and an Asp-95 to Asn or Gly mutation in GyrA. All three isolates with two or three mutations contained the Ser-91-to-Phe GyrA mutation. Eleven of the 14 isolates with the single Ser-91-to-Phe mutation within GyrA and all 3 isolates with two or three mutations persisted after pazufloxacin treatment. On the other hand, all 15 wild-type and 9 mutant isolates with a substitution at codon Ala-75 or Asp-95 were eradicated. The mean MIC of pazufloxacin for mutants with the single Ser-91-to-Phe mutation in GyrA was 66-fold higher than that for the wild type. The results obtained in this study suggest that a high prevalence of fluoroquinolone-resistant gonococcal isolates with the Ser-91-to-Phe mutation in GyrA reduced the efficacy of pazufloxacin as treatment for gonococcal urethritis.

Salmonella enterica serovar Paratyphi A isolated from a hard-to-heal diabetic ulcer: a case report

2020 ◽  
Vol 29 (1) ◽  
pp. 12-15
Author(s):  
Ayomi Dilhari ◽  
Sujatha Pathirage ◽  
Chinthika Gunasekara ◽  
Neluka Fernando ◽  
Deepaka Weerasekara ◽  
...  
Keyword(s):  
Type Ii Diabetes ◽  
Susceptibility Testing ◽  
Type Ii ◽  
Antibiotic Susceptibility Testing ◽  
Delayed Wound Healing ◽  
Diabetic Ulcer ◽  
History Of ◽  
Diabetic Wounds ◽  
Wound Tissue

Chronically infected diabetic wounds have a polymicrobial aetiology. However, Salmonella Paratyphi A is a very rare cause of wound infection. A 76-year-old female patient with type II diabetes presented with a wound on the left leg of two months' duration. The wound was painful, erythematous and a thick, foul-smelling discharge was present. There was a history of delayed wound healing. Salmonella Paratyphi A and Pseudomonas aeruginosa were isolated from the wound tissue. The patient was treated with cefuroxime and cloxacillin empirically and following the antibiotic susceptibility testing (ABST) report, ciprofloxacin was given for 10 days. The wound was treated with multiple debridements and topical antiseptic. On follow-up, the patient remained afebrile with subsiding discharge from the ulcer. This is the first reported case of Salmonella Paratyphi A from an infected diabetic ulcer in Sri Lanka and it serves to further define the spectrum of illnesses caused by this uncommon pathogen.

Rare Association of Klippel Feil Syndrome with Cleft Palate and Congenital Cardiac Deformities: A Case Report

2010 ◽  
Vol 35 (2) ◽  
pp. 213-216 ◽  
Author(s):  
Priya Subramaniam ◽  
KL Girish Babu ◽  
Sony Sugnani
Keyword(s):  
Cardiac Surgery ◽  
Case Report ◽  
Speech Therapy ◽  
Interdisciplinary Approach ◽  
Coarctation Of Aorta ◽  
Short Neck ◽  
Oral Rehabilitation ◽  
Rare Association ◽  
Neck Mobility

Klippel Feil Syndrome comprises of three characteristic deformities of short neck, a low dorsal hair line and restricted neck mobility. This is a case report of Klippel Feil Syndrome and its rare association with cleft of hard and soft palate, coarctation of aorta, dextrocardia and situs inversus. An interdisciplinary approach towards the management included cardiac surgery, cleft repair and complete oral rehabilitation of the patient. Presently the patient is undergoing speech therapy and is under regular follow up.

scholarly journals Unsolved Mystery of Synchronous Metastatic Adenocarcinoma and Echinococcus Cystic Infection, a Major Break Through in Clinical Oncology: A Case Report

2020 ◽  
Author(s):  
Aamer Ubaid ◽  
Farishta Waheed ◽  
Awais Naeem
Keyword(s):  
Case Report ◽  
Immune System ◽  
Previous History ◽  
Unknown Primary ◽  
Metastatic Adenocarcinoma ◽  
Zoonotic Infection ◽  
Cestode Species ◽  
Major Break ◽  
History Of

Echinococcus cystic infection is a zoonotic infection caused by the larval stage of cestode species belonging to the genus Echinococcus. Through the modulation of the immune system by this parasite, there is an established link of this infection with the metastasis and progression of a tumor. We present a case of a patient with synchronous findings of metastatic adenocarcinoma with unknown primary along with the previous history of echinococcal infection, which highlights the need for prompt management of such infections with a regular follow up of such patients.

scholarly journals Prosthetic Hip Loosening Due to Brucellar Infection: Case Report and Literature Review

2016 ◽  
Vol 6 (4) ◽  
Author(s):  
Anis Tebourbi ◽  
Khaled Hadhri ◽  
Mohamed Ben Salah ◽  
Ramzi Bouzidi ◽  
Mondher Kooli
Keyword(s):  
Case Report ◽  
Occupational Exposure ◽  
Literature Review ◽  
Functional Recovery ◽  
Total Joint Arthroplasty ◽  
Joint Arthroplasty ◽  
Implant Loosening ◽  
Zoonotic Infection ◽  
Prosthetic Infection

Context:Brucellosis is actually considered to be the commonest zoonotic infection worldwide; conversely prosthetic infection due to brucella is extremely rare. Although diagnostic is easily achieved, management of such situations is extremely challenging.AimsTo report the case of prosthetic hip loosening due to brucellar infection, discuss management manners and to summarize data about 19 cases reported in the literature.MethodsWe report the case of a 73-year-old woman with brucellar prosthetic hip loosening treated with 2-stage exchange of the prosthesis and prolonged double antibiotherapyResultsAt two years follow up the patient is pain free with total functional recovery and no clinical and radiographic signs of prosthetic looseningConclusionsBrucella should be evocated as a cause of total joint arthroplasty infection especially in patients from endemic regions and with occupational exposure. Antibiotic treatment alone can be followed if there are no signs of implant loosening. Tow stage revision should be considered in other cases. 

scholarly journals Successful management of mandibular first molars with endodontic-periodontal lesions – Two case reports

2021 ◽  
Vol 62 (2) ◽  
Author(s):  
Shirin Behdad ◽  
◽  
Gonçalo Caramês ◽  
Beatriz Pereira ◽  
Mariana Pires ◽  
...  
Keyword(s):  
Case Report ◽  
Case Reports ◽  
Interdisciplinary Approach ◽  
Regenerative Therapy ◽  
Successful Management ◽  
Present Case Report ◽  
Natural Dentition ◽  
Vascular Connections ◽  
Periodontal Healing

The interrelationship between pulpal and periodontal disease primarily occurs through the intimate anatomic and vascular connections between the pulp and the periodontium. The purpose of this case report is to present the treatment of two cases of mandibular first molars displaying endodontic-periodontal lesions with and without the use of regenerative bone techniques. The endodontic treatments were performed under an operating microscope in two appointments. Later, periodontal therapy was performed with a non-surgical approach in one case and with guided bone regeneration in the other. A 12-month radiographic and clinical follow-up showed periapical and periodontal healing in both cases. The present case report demonstrates that an interdisciplinary approach can help improve the prognosis and maintain natural dentition. Moreover, periodontal regenerative therapy can be performed to guide the wound healing towards the regeneration of lost periodontal structures.

scholarly journals An Interdisciplinary Approach for Hypoplastic Amelogenesis Imperfecta: A Case Report

2018 ◽  
Vol 12 (1) ◽  
pp. 466-475 ◽  
Author(s):  
Gulfem Ergun ◽  
Ayse Seda Ataol
Keyword(s):  
Case Report ◽  
Multidisciplinary Treatment ◽  
Interdisciplinary Approach ◽  
Clinical Findings ◽  
Amelogenesis Imperfecta ◽  
Radiographic Examination ◽  
Contact Points ◽  
Tooth Discoloration ◽  
Occlusal Wear

Introduction: Generally, the appropriate rehabilitation concepts of patients with Amelogenesis Imperfecta (AI) should include a multidisciplinary treatment approach. Case Report: This case report describes full mouth rehabilitation of a patient with AI. A 20 years old woman was referred to our clinic with a chief complaint of tooth discoloration, diastema, unsatisfactory esthetics and slight tooth sensitivity. Clinical, histological and radiographic examination revealed hypoplastic AI. Short crowns, diastema, occlusal wear with exposed dentin in the posterior areas, the lack of contact points, dental caries and discoloration were the other clinical findings. Results: As a result of the periodontal and prosthetic evaluation, gingivectomy and ostectomy were planned, and they followed a full mouth fixed prosthetic restoration. Conclusion: There was no complication or complaint in a 3-year follow-up. At the end of this follow-up period, the patient was satisfied with esthetics, function and phonation properties of her prostheses.

scholarly journals Interdisciplinary planning as a landmark for treatment: Case report with a 2-years follow-up

2018 ◽  
Vol 23 (6) ◽  
pp. 41.e1-41.e12
Author(s):  
Roberto Perasso ◽  
Monica Imelio ◽  
Renato Alcidi
Keyword(s):  
Case Report ◽  
Treatment Plan ◽  
Interdisciplinary Approach ◽  
Deep Bite ◽  
Significant Correction ◽  
Natural Teeth ◽  
Points Of View ◽  
Abstract Case ◽  
The Right

Abstract Case report: young adult woman with esthetic complaints regarding her smile and frontal teeth aspect. At first glance, the problem seemed to be only the shape of the lateral upper incisors and a small diastema between the central incisors. The diagnosis shared between the orthodontist and the prosthetist led us to consider some other important aspects, such as the deep bite, the teeth inclination and the lips support. All these findings led us to consider that the right way to improve the esthetics of the patient’s smile was to plan an orthodontic treatment. This would serve not only for the distribution of the spaces, but mostly it would improve all other problems, before the restoration of the upper lateral teeth with two ceramic veneers. Results: the treatment plan achieved the right distribution of spaces for upper lateral incisors, significant correction of the incisors inclination with important reduction of overbite and better lip support, upper laterals restorations with ceramic feldspathic veneers, obtaining a good integration with natural teeth satisfying patient complaint. Conclusion: in cases which involve interdisciplinary approach, the fundamental step comes from the beginning, when only an initial diagnosis shared among the team of specialists can define the patient problems from different points of view. In this way, we can better understand the competency fields and plan the right treatment and time sequence.

scholarly journals Immune Thrombocytopenia and JAK2V617F Positive Essential Thrombocythemia: Literature Review and Case Report

2017 ◽  
Vol 2017 ◽  
pp. 1-4
Author(s):  
M. A. Sobas ◽  
T. Wróbel ◽  
K. Zduniak ◽  
M. Podolak-Dawidziak ◽  
J. Rybka ◽  
...  
Keyword(s):  
Case Report ◽  
Literature Review ◽  
Essential Thrombocythemia ◽  
Case History ◽  
Immune Thrombocytopenia ◽  
Clinical Presentation ◽  
Predisposing Factor ◽  
Platelet Production

We present the case where immune thrombocytopenia (ITP) and essential thrombocythemia (ET) sequentially appeared in the space of twenty-one years of follow-up. Impaired platelet production is present in both diseases, but clinical presentation and treatment are different. On the basis of this case history a possible role of autoimmunity as a predisposing factor to myeloproliferation has been discussed.

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