Drug use-related right-sided infective endocarditis complicated by empyema and bronchopleural fistula

2022 ◽  
Vol 15 (1) ◽  
pp. e246663
Author(s):  
Lindsey M Shain ◽  
Taha Ahmed ◽  
Michele L Bodine ◽  
Jennifer G Bauman

Right-sided infective endocarditis is frequently accompanied by septic pulmonary emboli, which may result in a spectrum of respiratory complications. We present the case of a 25-year-old woman diagnosed with infective endocarditis secondary to intravenous drug use. During a long and arduous hospital course, the patient developed empyema with bronchopleural fistula, representing severe but uncommon sequelae that may arise from this disease process. She was treated with several weeks of antibiotics as well as surgical thorascopic decortication and parietal pleurectomy.

Author(s):  
Kendrea L. Todt ◽  
Sandra P. Thomas

BACKGROUND: The number of patients admitted with infective endocarditis (IE) from intravenous drug use (IVDU) in Appalachia is increasing, a direct downstream effect of the opioid crisis. Extant literature highlights the pejorative attitudes health care workers have toward patients with substance use disorder, with nurses among the most punitive. Rather than describe attitudes, the purpose of this study was to describe the lived experiences of nurses caring for patients diagnosed with IE from IVDU in Appalachia. OBJECTIVE: To describe an unexplored phenomenon in Appalachia to inform nursing practice, nursing education, and health policy. METHOD: Qualitative phenomenological study using the University of Tennessee method based on the tenets of Maurice Merleau-Ponty. Nine nurses (ages 29-53 years) recruited using purposive and snowball sampling participated in unstructured phenomenological interviews. RESULTS: The essential meaning or central theme of the nurse experience working with these patients was a sense of hopelessness/hope, with four interrelated themes derived from the central theme: (1) guarding/escaping, (2) responsibility and revulsion, (3) apathy/empathy, and (4) grief and sorrow/cold and unemotional. Universally, nurses perceived caring for this population as futile, feeling a sense of powerlessness to change the outcome. CONCLUSIONS: These care experiences frustrated nurses, who described being physically and emotionally drained. To improve care delivery and improve patient outcomes, emphasis must be placed on nurse addiction education and standardizing nurse to patient with substance use disorder ratios to decrease work-related stress on nurses.


2018 ◽  
Author(s):  
Sam Straw ◽  
Wazir Baig ◽  
Richard Gillott ◽  
Francesco Pirone ◽  
Jonathan Sandoe

2019 ◽  
Vol 2019 ◽  
pp. 1-4 ◽  
Author(s):  
Achilleas Nikolakopoulos ◽  
Nikolaos Koutsogiannis ◽  
Panagiota Xaplanteri ◽  
Charalambos Gogos ◽  
Fevronia Kolonitsiou ◽  
...  

Introduction.Serratia marcescensis a rare cause of infective endocarditis and has almost exclusively been associated with intravenous drug use and hospital-acquired infections. Here, we present a case of infective endocarditis caused bySerratia marcescensin an otherwise healthy, nonintravenous drug-using male patient.Case Report. A 41-year-old man presented with hypertension and hemoptysis. Blood cultures were obtained that showed bacteremia bySerratia marcescens. An echocardiogram was carried out that revealed severe mitral regurgitation accompanying ruptured mitral chordae tendineae. The patient received the appropriate antibiotic treatment, without further surgical intervention.Discussion.Hospital-acquired infections bySerratiaspecies are a common problem in medical practice and have been attributed to specialized interventional procedures. Taking into consideration the patient’s immunocompetence and lack of intravenous drug use, it is possible that bacteremia could be attributed to a medical procedure. Moreover, in contrast to most cases described in the literature, no surgery was performed.


2017 ◽  
Vol 2017 ◽  
pp. 1-3 ◽  
Author(s):  
Eddie Y. Liu ◽  
Jennifer Crawford ◽  
Haissam Haddad

We present a case of hemothorax due to ruptured mycotic aneurysm in three intercostal arteries in a 40-year-old male with methicillin-resistant Staphylococcus aureus infective endocarditis (IE) due to intravenous drug use. Microcoil embolization and thoracotomy successfully achieved hemostasis. Mycotic aneurysm is a rare complication of IE and is usually found in the intracranial vessels. Ruptured mycotic aneurysm in the intercostal arteries can be associated with IE and can present as acute hemothorax.


Cureus ◽  
2021 ◽  
Author(s):  
Deena Dahshan ◽  
Mohamed Suliman ◽  
Ebad U Rahman ◽  
Zachary Curtis ◽  
Ellen Thompson

2020 ◽  
Vol 61 (6) ◽  
pp. 678-687
Author(s):  
Vani Ray ◽  
Mindy R. Waite ◽  
Frank C. Spexarth ◽  
Sandra Korman ◽  
Susan Berget ◽  
...  

2020 ◽  
Vol 10 (03) ◽  
pp. e288-e293
Author(s):  
Adebayo Adesomo ◽  
Veronica Gonzalez-Brown ◽  
Kara M. Rood

Abstract Objective An increase in opioid use disorder and subsequent intravenous drug use has led to an increase in sequalae that may complicate pregnancy, such as infective endocarditis. Infective endocarditis has the potential for significant maternal and neonatal morbidity and mortality. We sought to examine the management considerations and clinical implications of intravenous drug use-related infective endocarditis in pregnancy from our center's experience. Study Design Retrospective study of management of pregnancies complicated by infective endocarditis as a result of active intravenous drug use at an academic tertiary care hospital from January 2012 through December 2019. Results Twelve women with active intravenous drug use histories were identified as having clinical and echocardiographic features consistent with infective endocarditis. Six women were discharged against medical advice and did not complete the full course of recommended antibiotic regimen. Eight women were started or continued on opioid agonist therapy during their hospitalization. Four neonates required neonatal intensive care unit admission for pharmacologic treatment for neonatal abstinence syndrome. Conclusion Management of intravenous drug use-associated infective endocarditis in pregnancy involves more than treating the acute condition. In pregnant women with opioid use disorder and infective endocarditis, addiction and chronic psychosocial conditions need to be addressed to optimize care.


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