Reactivation of IgA vasculitis following COVID-19 vaccination

A 23-year-old man presented to the acute assessment unit with acute-onset haematuria within 24 hours of receiving his second dose of the Pfizer-BioNTech COVID-19 vaccine. He had been diagnosed with IgA vasculitis 8 months previously. IgA vasculitis is an autoimmune condition characterised by palpable purpura affecting the lower limbs, abdominal pain, arthralgia and renal disease. He was diagnosed with an acute exacerbation of IgA vasculitis and was discharged with oral prednisolone. Reactivation or first presentation of IgA vasculitis is a rare but increasingly recognised complication of COVID-19 vaccination. This is an important new differential in the assessment of patients with haematuria following COVID-19 vaccination.

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IgA vasculitis with terminal ileitis and giant duodenum ulceration and review of the literatures

10.21203/rs.3.rs-944716/v1 ◽

2021 ◽

Author(s):

Wang Fengge ◽

Wang Xiaoli ◽

Wu Daiqin

Keyword(s):

Abdominal Pain ◽

Acute Abdomen ◽

Early Recognition ◽

Gastrointestinal Symptoms ◽

Lower Limbs ◽

Iga Vasculitis ◽

Terminal Ileitis ◽

Patients Âgés ◽

Female Patients ◽

Schonlein Purpura

Abstract BackgroundImmunoglobulin A vasculitis (IgA V), formerly Henoch–Schönlein purpura, is one of the most common self-limiting vasculitis in children. In 15-20% IgA V cases, gastrointestinal symptoms precede the rashes,they no specific gastrointestinal symptoms and often present as acute abdomen, making the diagnosis difficult.Case presentationWe present two female patients, ages 8 years old and 5 years old, who presented to vomiting and abdominal pain, rashes appeared on the lower limbs a few days later, they were subsequently diagnosed with IgA V. Both patients were given IV methylprednisolone, achieved benign clinical results.ConclusionsWhen gastrointestinal symptoms precede the rashes, it is difficult to diagnose IgA vasculitis, resulting in unnecessary surgery. Early recognition and treatment will promote the remission of the children and avoid unnecessary surgery.

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Meningismus in IgA vasculitis (Henoch–Schönlein purpura)

Pediatria i Medycyna Rodzinna ◽

10.15557/pimr.2020.0074 ◽

2020 ◽

Vol 16 (4) ◽

pp. 414-417

Author(s):

Katarzyna Gmachowska ◽

Keyword(s):

Abdominal Pain ◽

Disease Duration ◽

Systemic Vasculitis ◽

Symptomatic Treatment ◽

Acute Onset ◽

Neurological Symptoms ◽

Meningococcal Sepsis ◽

Iga Vasculitis ◽

Meningeal Irritation ◽

Schonlein Purpura

IgA vasculitis is the most common acute systemic vasculitis in children. Typical symptoms include cutaneous purpura not associated with thrombocytopenia, acute-onset abdominal pain, arthritis, renal symptoms and, less commonly, neurological symptoms. The disease is usually mild and self-limiting. Although the aetiology of IgA vasculitis is unknown, autoimmune involvement is suspected. Symptomatic treatment is mainly used; therapeutic method that would reduce disease duration and prevent recurrence is unknown. Meningococcal sepsis should always be ruled out in a child with cutaneous purpura. We present a case of a 4-year-old boy with IgA vasculitis who developed symptoms of meningeal irritation.

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Acute-onset paraplegia as an unexpected complication under general anesthesia in supine position during abdominal endovascular aneurysm repair: a case report

JA Clinical Reports ◽

10.1186/s40981-021-00447-7 ◽

2021 ◽

Vol 7 (1) ◽

Author(s):

Atsushi Morio ◽

Hirotsugu Miyoshi ◽

Noboru Saeki ◽

Yukari Toyota ◽

Yasuo M. Tsutsumi

Keyword(s):

Spinal Cord ◽

General Anesthesia ◽

Supine Position ◽

Spinal Cord Ischemia ◽

Endovascular Aneurysm Repair ◽

Acute Onset ◽

Lower Limbs ◽

Canal Stenosis ◽

Cord Injury ◽

Aneurysm Repair

Abstract Background Acute onset paraplegia after endovascular aneurysm repair (EVAR) is a rare but well-known complication. We here show a 79-year-old woman with paraplegia caused by static and dynamic spinal cord insult not by ischemia after EVAR. Case presentation The patient underwent EVAR for abdominal aortic aneurism under general anesthesia in the supine position. She had a medical history of lumbar canal stenosis. After the surgery, we recognized severe paraplegia and sensory disorder of lower limbs. Although the possibility of spinal cord ischemia was considered at that time, postoperative magnetic resonance imaging (MRI) revealed burst fracture of vertebra and compressed spinal cord. Conclusions Patients with spinal canal stenosis can cause extrinsic spinal cord injury even with weak external forces. Thus, even after EVAR, it is important to consider extrinsic factors as the cause of paraplegia.

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Case 2: Acute Onset of Vomiting, Abdominal Pain, and Constipation in an 18-month-old Girl

Pediatrics in Review ◽

10.1542/pir.2016-0172 ◽

2017 ◽

Vol 38 (7) ◽

pp. 332-333

Author(s):

Anya Kleinman

Keyword(s):

Abdominal Pain ◽

Acute Onset

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Spontaneous Uterine Rupture in a Preterm Pregnancy following Myomectomy

Case Reports in Obstetrics and Gynecology ◽

10.1155/2016/6195621 ◽

2016 ◽

Vol 2016 ◽

pp. 1-4 ◽

Cited By ~ 6

Author(s):

Claire Sutton ◽

Prue Standen ◽

Jade Acton ◽

Christopher Griffin

Keyword(s):

Abdominal Pain ◽

Caesarean Section ◽

Uterine Rupture ◽

Good Condition ◽

Acute Onset ◽

Uterine Wall ◽

Unusual Presentation ◽

Postoperative Course ◽

Spontaneous Uterine Rupture ◽

History Of

A 44-year-old nulliparous woman was transferred to a tertiary obstetric hospital for investigation of acute onset abdominal pain. She was at gestation of 32 weeks and 2 days with a history of previous laparoscopic fundal myomectomy. An initial bedside ultrasound demonstrated oligohydramnios. Following an episode of increased pain early the following morning, a formal ultrasound diagnosed a uterine rupture with the fetal arm extending through a uterine rent. An uncomplicated classical caesarean section was performed and the neonate was delivered in good condition but with a bruised and oedematous right arm. The neonate was transferred to the Special Care Nursery for neonatal care. The patient had an uncomplicated postoperative course and was discharged home three days following delivery. This is an unusual presentation of uterine rupture following myomectomy where the fetal arm had protruded through the uterine wall.

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Relationship of obesity and social deprivation with non-specific abdominal pain in young women presenting to a surgical assessment unit

International Journal of Surgery ◽

10.1016/j.ijsu.2011.07.371 ◽

2011 ◽

Vol 9 (7) ◽

pp. 570

Author(s):

Jason Appleton ◽

Thomas Pinkney ◽

Steve Pandey ◽

Anant Desai ◽

Tariq Ismail ◽

...

Keyword(s):

Abdominal Pain ◽

Young Women ◽

Social Deprivation ◽

Assessment Unit ◽

Relationship Of

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Pathologic Quiz Case: An 11-Year-Old Boy With Acute-Onset Right Lower Abdominal Pain

Archives of Pathology & Laboratory Medicine ◽

10.5858/2004-128-239-pqcayb ◽

2004 ◽

Vol 128 (2) ◽

pp. 239-240 ◽

Cited By ~ 1

Author(s):

Sa Wang ◽

Oluwole Fadare

Keyword(s):

Abdominal Pain ◽

Lower Abdominal Pain ◽

Acute Onset

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HENOCH-SCHÖNLEIN PURPURA Z NEZNAČILNIM POTEKOM BOLEZNI – predstavitev treh primerov in pregled literature

Slovenian Medical Journal ◽

10.6016/zdravvestn.1294 ◽

2016 ◽

Vol 85 (2) ◽

Author(s):

Daša Kumprej ◽

Tomaž Krenčnik ◽

Aleksandra Aleksandrova Oberstar ◽

Nataša Toplak

Keyword(s):

Abdominal Pain ◽

Renal Disease ◽

Blood Vessels ◽

Current Literature ◽

Atypical Presentation ◽

Disease Course ◽

Henoch Schonlein Purpura ◽

Skin Manifestation ◽

Schonlein Purpura ◽

Henoch Schönlein Purpura

Background: Henoch-Schönlein purpura is the most common vasculitis of small blood vessels in children. The diagnosis of the disease is confirmed in a patient with a specific rash, joint inflamation, abdominal pain or renal disease. The specific rash is necesary for the confirmation of the diagnosis. Henoch-Schönlein purpura can rarely present with a complication withot a prior presentation of the rash. In these cases diagnosis is difficult until the presentation of the specific skin manifestation. In the majority of patients the disease course is not complicated and has a good prognosis.Conclusion: In this article we present three patients with an atypical presentation of the disease and a review of current literature on the topic.

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