I am an international A level student hoping to study medicine at Oxford. The website says that I would have to attend an initial interview. What are the tutors looking for in an ideal candidate and how can I prepare?

BMJ ◽  
2005 ◽  
Vol 330 (7488) ◽  
pp. s72.2-s72
Author(s):  
Brian Angus
1993 ◽  
Author(s):  
Beatriz Galilea ◽  
Aina Plaza ◽  
Marisa Arumi
Keyword(s):  

2020 ◽  
Author(s):  
Ryan Weber ◽  
Martin McCullagh

<p>pH-switchable, self-assembling materials are of interest in biological imaging and sensing applications. Here we propose that combining the pH-switchability of RXDX (X=Ala, Val, Leu, Ile, Phe) peptides and the optical properties of coumarin creates an ideal candidate for these materials. This suggestion is tested with a thorough set of all-atom molecular dynamics simulations. We first investigate the dependence of pH-switchabiliy on the identity of the hydrophobic residue, X, in the bare (RXDX)<sub>4</sub> systems. Increasing the hydrophobicity stabilizes the fiber which, in turn, reduces the pH-switchabilty of the system. This behavior is found to be somewhat transferable to systems in which a single hydrophobic residue is replaced with a coumarin containing amino acid. In this case, conjugates with X=Ala are found to be unstable and both pHs while conjugates with X=Val, Leu, Ile and Phe are found to form stable β-sheets at least at neutral pH. The (RFDF)<sub>4</sub>-coumarin conjugate is found to have the largest relative entropy value of 0.884 +/- 0.001 between neutral and acidic coumarin ordering distributions. Thus, we posit that coumarin-(RFDF)<sub>4</sub> containing peptide sequences are ideal candidates for pH-sensing bioelectronic materials.</p>


2013 ◽  
Vol 2 (4) ◽  
pp. 80-85 ◽  
Author(s):  
R. K Chandrakumar Singh ◽  
Khuraijam Sanatombi Devi

2020 ◽  
Vol 16 ◽  
Author(s):  
Munair Badshah ◽  
Hanif Ullah ◽  
Fazli Wahid ◽  
Taous Khan

Background: Bacterial cellulose (BC) is purest form of cellulose as it is free from pactin, lignin, hemicellulose and other active constituents associated with cellulose derived from plant sources. High biocompatibility and easy molding into desired shape make BC an ideal candidate for applications in biomedical field such as tissue engineering, wound healing and bone regeneration. In addition to this, BC has been widely studied for applications in the delivery of proteins and drugs in various forms via different routes. However, BC lacks therapeutic properties and resistance to free movement of small molecules i.e., gases and solvents. Therefore, modification of BC is required to meet the research ad market demand. Methods: We have searched the updated data relevant to as-synthesized and modified BC, properties and applications in various fields using Web of science, Science direct, Google and PubMed. Results: As-synthesized BC possesses properties such as high crystallinity, well organized fibrous network, higher degree of polymerization, and ability of being produced in swollen form. The large surface area with abundance of free accessible hydroxyl groups makes BC an ideal candidate for carrying out surface functionalization to enhance its features. The various reported surface modification techniques including, but not limited to, are amination, methylation and acetylation. Conclusion: In this review, we have highlighted various approaches made for BC surface modification. We have also reported enhancement in the properties of modified BC and potential applications in different fields ranging from biomedical science to drug delivery and paper-making to various electronic devices.


2014 ◽  
Vol 7 (16) ◽  
pp. 3216-3221
Author(s):  
R. Malathi ◽  
M. Karthik kumar ◽  
S. Ramkumar ◽  
V. Prakash

2021 ◽  
Vol 37 (01) ◽  
pp. 045-052
Author(s):  
Mario Bazanelli Junqueira Ferraz ◽  
Guilherme Constante Preis Sella

AbstractNasal dorsal preservation surgery was described more than 100 years ago, but recently has gained prominence. Our objective is to show the surgical technique, the main indications and counterindications, and the complications. It is a technique that does not cause the detachment of the upper lateral cartilage (ULC) from the nasal septum, and has the main following sequence: preparation of the septum and its resection can be at different levels (high or low, i.e., SPAR [septum pyramidal adjustment and repositioning] A or B); preparation of the pyramid; transversal osteotomy; lateral osteotomy(s); and septopyramidal adjustment. The result is a nose with a lower radix than the original, a deprojection of the nasal dorsum tending to maintain its original shape; an increase in the interalar distance (IAD) and enlargement of the nasal middle ⅓; and loss of projection of the nasal tip and roundness of the nostrils. Thus, the ideal candidate is the one who benefits from such side effects, that is: tension nose, that is, high radix with projected dorsum, projected anterior nasal septal angle (ANSA), narrow middle ⅓, narrow IAD, thin nostrils and straight perpendicular plate of the ethmoid (PPE), and, depending on the characteristics, the deviated nose. The counterindications are low radix, irregularities in the nasal dorsum, ANSA lower than rhinion, and a wide middle ⅓. And the main stigmas are: a nose with a very low radix, middle ⅓ enlarged, residual hump, and saddling of the supratip area. Other issues of this technique are: the shape of the radix; the need or not to remove PPE; wide dorsum; irregular dorsum; ANSA lower than rhinion; weak cartilages; long nasal bone; deviated PPE; and obsessive patient. We conclude that this is a great technique for noses with characteristics suitable to it; care must be taken with the stigmas it can cause.


Polymers ◽  
2021 ◽  
Vol 13 (3) ◽  
pp. 412
Author(s):  
Sam Swingler ◽  
Abhishek Gupta ◽  
Hazel Gibson ◽  
Marek Kowalczuk ◽  
Wayne Heaselgrave ◽  
...  

Bacterial cellulose (BC) is an extracellular polymer produced by Komagateibacter xylinus, which has been shown to possess a multitude of properties, which makes it innately useful as a next-generation biopolymer. The structure of BC is comprised of glucose monomer units polymerised by cellulose synthase in β-1-4 glucan chains which form uniaxially orientated BC fibril bundles which measure 3–8 nm in diameter. BC is chemically identical to vegetal cellulose. However, when BC is compared with other natural or synthetic analogues, it shows a much higher performance in biomedical applications, potable treatment, nano-filters and functional applications. The main reason for this superiority is due to the high level of chemical purity, nano-fibrillar matrix and crystallinity. Upon using BC as a carrier or scaffold with other materials, unique and novel characteristics can be observed, which are all relatable to the features of BC. These properties, which include high tensile strength, high water holding capabilities and microfibrillar matrices, coupled with the overall physicochemical assets of bacterial cellulose makes it an ideal candidate for further scientific research into biopolymer development. This review thoroughly explores several areas in which BC is being investigated, ranging from biomedical applications to electronic applications, with a focus on the use as a next-generation wound dressing. The purpose of this review is to consolidate and discuss the most recent advancements in the applications of bacterial cellulose, primarily in biomedicine, but also in biotechnology.


Plants ◽  
2021 ◽  
Vol 10 (5) ◽  
pp. 929
Author(s):  
Hanadi Sawalha ◽  
Rambod Abiri ◽  
Ruzana Sanusi ◽  
Noor Azmi Shaharuddin ◽  
Aida Atiqah Mohd Noor ◽  
...  

Nanotechnology is a promising tool that has opened the doors of improvement to the quality of human’s lives through its potential in numerous technological aspects. Green chemistry of nanoscale materials (1–100 nm) is as an effective and sustainable strategy to manufacture homogeneous nanoparticles (NPs) with unique properties, thus making the synthesis of green NPs, especially metal nanoparticles (MNPs), the scientist’s core theme. Researchers have tested different organisms to manufacture MNPs and the results of experiments confirmed that plants tend to be the ideal candidate amongst all entities and are suitable to synthesize a wide variety of MNPs. Natural and cultivated Eucalyptus forests are among woody plants used for landscape beautification and as forest products. The present review has been written to reflect the efficacious role of Eucalyptus in the synthesis of MNPs. To better understand this, the route of extracting MNPs from plants, in general, and Eucalyptus, in particular, are discussed. Furthermore, the crucial factors influencing the process of MNP synthesis from Eucalyptus as well as their characterization and recent applications are highlighted. Information gathered in this review is useful to build a basis for new prospective research ideas on how to exploit this woody species in the production of MNPs. Nevertheless, there is a necessity to feed the scientific field with further investigations on wider applications of Eucalyptus-derived MNPs.


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