Breast screening debate can be settled only with high quality randomised controlled trial

BMJ ◽  
2012 ◽  
Vol 344 (feb21 1) ◽  
pp. e737-e737
Author(s):  
A. P. Corder
The Lancet ◽  
2017 ◽  
Vol 390 ◽  
pp. S45 ◽  
Author(s):  
Sarah Huf ◽  
Dominic King ◽  
Gaby Judah ◽  
Clare Fuller ◽  
Ivo Vlaev ◽  
...  

1994 ◽  
Vol 1 (4) ◽  
pp. 245-248 ◽  
Author(s):  
Patricia Meldrum ◽  
Deborah Turnbull ◽  
Hilary M Dobson ◽  
Carol Colquhoun ◽  
W Harper Gilmour ◽  
...  

Firstly, to determine if attendance for second round mammography screening in those sent a tailored letter (that is, making reference to their screening history) is increased compared with those sent a standard letter; secondly, to investigate the acceptability of tailored letters. North West Glasgow Breast Screening Centre. A randomised controlled trial. Overall attendance was unrelated to whether the women were sent a tailored or standard letter; 60% of those sent the standard letter attended (922/1531) compared with 62% of those sent the tailored letter (956/1552) (χ2 = 0·61, P = 0·4) (difference 2%; 95% confidence interval − 2% to 5%). There were no significant differences in percentage attendance within each of the study subgroups: women who attended previously and received an all clear result, women who attended previously and received a false positive result, women who were invited previously and failed to attend, and women who were previously too young to be invited for screening. However, there was a statistically significant difference in percentage attendance between these four groups, independent of letter type (χ2 = 510, P<0·00001). Although women found the letters acceptable and understandable, they did not seem to pay close attention to the content. Tailoring invitation letters does not have a significant effect on uptake rates for breast screening and does not justify the additional workload required.


The Lancet ◽  
2013 ◽  
Vol 382 ◽  
pp. S9 ◽  
Author(s):  
Robert Kerrison ◽  
Heema Shukla ◽  
Deborah Cunningham ◽  
Oyinlola Oyebode ◽  
Ellis Friedman

Author(s):  
Annie S. Anderson ◽  
Huey Yi Chong ◽  
Angela M. Craigie ◽  
Peter T. Donnan ◽  
Stephanie Gallant ◽  
...  

An amendment to this paper has been published and can be accessed via the original article.


2012 ◽  
Vol 2012 ◽  
pp. 1-6 ◽  
Author(s):  
Lindsay J. L. Forbes ◽  
Alice S. Forster ◽  
Rachael H. Dodd ◽  
Lorraine Tucker ◽  
Rachel Laming ◽  
...  

Background. Women over 70 with breast cancer have poorer one-year survival and present at a more advanced stage than younger women. Promoting early symptomatic presentation in older women may reduce stage cost effectively and is unlikely to lead to overdiagnosis. After examining efficacy in a randomised controlled trial, we piloted a brief health professional-delivered intervention to equip women to present promptly with breast symptoms, as an integral part of the final invited mammogram at age~70, in the English National Health Service Breast Screening Programme.Methods. We trained mammographers, who then offered the intervention to older women in four breast screening services. We examined breast cancer awareness at baseline and one month in women receiving the intervention, and also in a service where the intervention was not offered.Results. We trained 27 mammographers to deliver the intervention confidently to a high standard. Breast cancer awareness increased 7-fold at one month in women receiving the intervention compared with 2-fold in the comparison service (odds ratio 15.2, 95% confidence interval 10.0 to 23.2).Conclusions. The PEP Intervention can be implemented in routine clinical practice with a potency similar to that achieved in a randomised controlled trial. It has the potential to reduce delay in diagnosis for breast cancer in older women.


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