scholarly journals Rubella virus infection and associated factors among pregnant women attending the antenatal care clinics of public hospitals in Hawassa City, Southern Ethiopia: a cross-sectional study

BMJ Open ◽  
2017 ◽  
Vol 7 (10) ◽  
pp. e016824 ◽  
Author(s):  
Biniam Tamirat ◽  
Siraj Hussen ◽  
Techalew Shimelis

ObjectiveTo assess the seroprevalence of recent/acute and past exposure to rubella virus infection and associated risk factors among pregnant women.DesignA hospital-based cross-sectional study.SettingThe study was conducted in two public hospitals in Hawassa City, Southern Ethiopia.ParticipantsA total of 422 pregnant women attending antenatal care clinics were selected using a systematic random sampling technique from March to June 2016.Outcome measuresData on sociodemography and related factors were collected using a structured questionnaire. Blood samples were also collected from each study participant and tested for antirubella IgM and IgG antibodies using ELISA. IgG seropositivity indicates past exposure to rubella (protective immunity). IgM seropositivity indicates recent exposure to rubella (or reinfection).ResultsThe seroprevalence of antirubella IgM and IgG antibodies was 2.1% and 86.3%, respectively. Thus, the rate of susceptibility to rubella virus infection among pregnant women was found to be 13.7%. A significant association between residence site and IgG seropositivity was observed, where urban dwellers had higher past rubella exposure compared with rural residents (crude OR 6.3; 95% CI 3.29 to 12.14, p<0.001).ConclusionThe high rate of rubella exposure and its similar distribution by sociodemography (except residence site) suggests the continuous transmission and endemicity of the infection in the study area. These findings emphasise the importance of introducing rubella-containing vaccine into routine childhood immunisation programme and vaccinating susceptible women of childbearing age.

2019 ◽  
Author(s):  
Amelo Bolka ◽  
Samson Gebremedhin

Abstract Background Previous studies reported contradicting findings about the association between intestinal parasitosis and maternal anemia. In this study we aimed to determine the prevalence of intestinal parasitic infection and its association with anemia among pregnant women in Wondo Genet district, Southern Ethiopia. Methods This facility-based cross-sectional study was conducted in June and July 2018. Pregnant women (n=352) were randomly drawn from five health centers using antenatal care follow-up lists. Trained data collectors administered the questionnaire. Capillary blood was collected and analyzed for hemoglobin using the HemoCue method. Stool sample was collected following standard procedure and analyzed for the presence and types of intestinal parasites using direct microscopy with Formalin-ether concentration technique. Association between intestinal parasitosis and anemia was measured using multivariable binary logistic regression analysis. The outputs are presented using adjusted odds ratio (AOR) with 95% confidence intervals (CI). Results The overall prevalence of intestinal parasitic infection was 38.7% (95% CI: 33.6-43.8%). One-tenth (9.7%) of the pregnant women were infected with polyparasites. Ascaris lumbricoides was the predominant infection encountered in 24.9% of the women. The other infections identified were: hookworms (11.2%), Giardia lamblia (5.4%), Entamoeba histolytica (3.4%), Trichuris trichiura (2.9%) and Schistosoma mansoni (2.3%). The mean (± standard deviation) hemoglobin concentration was 12.3 (±1.9) g/dl and 31.5% (95% CI: 26.6-36.4%) women were anemic (hemoglobin < 11 g/dl). The prevalence of anemia among women infected with intestinal parasite (55.6%) was substantially higher than the prevalence in their counterparts (16.4%) (p<0.001). In a multivariable model adjusted for multiple potential confounders including socio-economic status indicators, the odds of anemia were six times increased (AOR=6.14, 95% CI: 2.04-18.45) among those affected by at least one intestinal parasite. Conclusion Strengthening the existing water, sanitation and hygiene programs and routine deworming of pregnant mothers may help to reduce the burden of both intestinal parasitic infection and anemia in pregnant women.


2018 ◽  
Author(s):  
Mende Mensa ◽  
Akililu Ayele ◽  
Biruk Wogayehu

AbstractBackgroundAvailability of essential medicines is necessary to maintain health of the community. In Ethiopia, availability of medicines was low (65%), with high expiry rate (8.24%), low patient knowledge on correct dosage (50.5%) and satisfaction on pharmacy services (74.5%). To avert these problems, the government had endorsed legislation on a system called “Auditable Pharmaceutical Transactions and Services (APTS)”. However, the outcomes and challenges in implementation of this system were not assessed.ObjectiveTo assess the implementation status of APTS and its challenges at public hospitals in Gamo Gofa Zone Southern Ethiopia, April 2017.MethodsFacility based Cross sectional study was conducted in two APTS implementing hospitals in Gamo Gofa zone. Semi structured Self-administered questionnaire was distributed to all pharmacy staffs in selected hospitals. APTS reports of 12 months (with different characteristics) were reviewed. Four hundred patients were interviewed by data collectors about patient knowledge and satisfaction using WHO questionnaire. The data were entered and analyzed using Statistical package for social science students/SPSS version 20. T-test and linear regression was used to evaluate significant differences between two hospitals with level of significance pre-set at p-value ≤0.05.ResultsAll dispensing units in primary hospital had six (75%) out of the eight essential equipment for dispensing practice. it was found that respondents in general hospital stated higher scores in general setting of outpatient pharmacy (4.58 Versus 4.25; P <0.001), but lower scores for availability and cost of medicines (4.24 vs 4.43; P<0.05) when compared with those in primary level hospital. There was no significant difference in instruction of medicine provided by dispenser (2.58 vs 2.59; P>0.05), dispenser client interaction (3.09 vs 4.08; P>0.05) and total satisfaction score (2.09 vs 2.02; P>0.05).Conclusion and recommendationsIn our study Quality of Auditable Pharmaceutical Transactions and Service was low, especially regarding patient knowledge about medicines, unaffordability of medicines, less availability of prescribed drugs, poor transparency of pharmaceutical transactions, insufficient counseling practice and limited facilities for dispensing such as, key medicines, formularies and standard guidelines. We therefore recommend the following measures responsible bodies to improve these gaps y taking administrative actions and providing continued education and training for dispensers.


2020 ◽  
Author(s):  
Sintayehu Mengesha ◽  
Mesay Hailu Dangisso

Abstract Background Stillbirth is an adverse pregnancy outcome of public health importance causing considerable psychosocial burden on parents and their family. Studies on stillbirth are scarce in southern Ethiopia. An assessment of stillbirths and associated factors in health care settings helps in devising strategies for tailored interventions. Therefore, we assessed the burden of stillbirths and associated factors in Yirgalem Hospital, southern Ethiopia. Methods: A facility based cross-sectional study was conducted between 1 August 2015 and 30 July 2016. We randomly selected medical records of pregnant women from a hospital delivery registry. Bivariate analysis was employed to assess the association between independent and dependent variables using chi-square with significant p-value. Multivariate logistic regression was used to identify independent risk factors for stillbirths and to control for confounding variables.Results: Of 374 reviewed records of pregnant women, 370 were included for the study. The magnitude of stillbirths was 92 per 1000 births. Fifteen (44.1%) of fetal deaths occurred after admission to the hospital. In multivariate logistic regression, stillbirths were higher among low birth-weight babies (<2500grams) (adjusted odds ratio (AOR): 10.70, 95% CI 3.18-35.97) than normal birth-weight babies (2500-<4000). Pregnant women who experienced a prolonged labour for more than 48 hours were 12 times (AOR: 12.15, 95% CI 1.76-84.12) more likely to have stillbirths than pregnant women without a prolonged labour. Pregnant women with obstetric complications were 18.9 times more likely to have stillbirths than pregnant women without obstetric complications. Similarly, pregnant women with at least two pregnancies were more likely to have stillbirths than pregnant women with less than two pregnancies (AOR: 4.39, 95% CI 1.21-15.85).Conclusion: We found a high burden of stillbirths in the study setting. Modifiable risk factors contributed to a higher risk of stillbirths; therefore, tailored interventions such as early identification and management of prolonged labour and obstetric complication at each level of health system could avert preventable stillbirths.


2021 ◽  
Author(s):  
Mekonnen Bogale ◽  
Bargude Balta

Abstract Introduction: Estimated 350 million people had been diagnosed for chronic HBV infection and 686,000 people die each year which is an important global public health. This study is expected to provide area-specific information for decision-makers by visualizing prevalence and its associated factors OF HBV.Objective: The aim of this study to access prevalence HBV sero-prevalence and associative factors among pregnant women’s attending ANC in public hospitals of Hawassa City , 2021.Method: A analytic cross sectional study was conducted among pregnant women at Public Hospital in Hawassa city from May 20-July 30/2021. A total of 320 participants were selected. Data were entered and analyzed using SPSS version 25.0. Descriptive statics used to determine prevalence of HBV; Bivariate and multivariate logistic regression analysis was done to identify the independent predictors of HBV status at p-value <0.05. Results:Results: From total of 320 pregnant women participated in the study twenty two are HBV positive which makes overall prevalence From total of 320 pregnant women participated in the study twenty two are HBV positive which makes overall prevalence [6.9 % (95%,CI (6.6%, 7.2%))]. in study area history of transfusion (AOR = 18.99, 95%CI, (2.1–171)). Pregnant women having history of vulvar ulcer were nearly fifteen times more likely to acquire HBV infection comparing having no history of vulvar ulcer (AOR = 14.78; 95%CI (1.12–194.4)) and Women who had history and those with contact jaundice patients (AOR = 127.6; 95%CI (12–134)) were independently predictors of HBV.Conclusion: Intermediate endemicity of prevalence of hepatitis HBV was detected in study area. Blood transfusion, history of Vulvar ulcer and history of contact with jaundice patient were found to be the determinant factors of sero-positivity of HBV. Awareness creation on HBV transmission and early screening of HBV at blood donation site important to reduce HBV endemicity.


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