Short-term and long-term revision rates after lumbar spine discectomy versus laminectomy: a population-based cohort study

Background/objectiveDegenerative diseases of the lumbar spine were managed with discectomy or laminectomy. This study aimed to compare these two surgical treatments in the postoperative revision rates.DesignA population-based cohort study from analysis of a healthcare database.SettingData were gathered from the Taiwan National Health Insurance Research Database (NHIRD).ParticipantsWe enrolled 16 048 patients (4450 women and 11 598 men) with a mean age of 40.34 years who underwent lumbar discectomy or laminectomy for the first time between 1 January 1997 and 31 December 2007. All patients were followed up for 5 years or until death.ResultsRevision rate within 3 months of the index surgery was significantly higher in patients who underwent discectomy (2.75%) than in those who underwent laminectomy (1.18%; p<0.0001). This difference persisted over the first year following the index surgery (3.38% vs 2.57%). One year afterwards, the revision rates were similar between the discectomy (9.75%) and laminectomy (9.69%) groups. The final spinal fusion surgery rates were also similar between the groups (11.25% vs 12.08%).ConclusionThe revision rate after lumbar discectomy was higher than that after laminectomy within 1 year of the index surgery. However, differences were not identified between patient groups for the two procedures with respect to long-term revision rates and the proportion of patients who required final spinal fusion surgery.

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Reoperation rates after posterior lumbar spinal fusion surgery according to preoperative diagnoses: A national population-based cohort study

Clinical Neurology and Neurosurgery ◽

10.1016/j.clineuro.2019.105408 ◽

2019 ◽

Vol 184 ◽

pp. 105408

Author(s):

Moon Soo Park ◽

Young-Su Ju ◽

Seong-Hwan Moon ◽

Tae-Hwan Kim ◽

Jae Keun Oh ◽

...

Keyword(s):

Cohort Study ◽

Spinal Fusion ◽

Population Based ◽

Lumbar Spinal Fusion ◽

Fusion Surgery ◽

National Population ◽

Spinal Fusion Surgery ◽

Lumbar Spinal ◽

Reoperation Rates

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Bone union after spinal fusion surgery using local bone in long-term bisphosphonate users: a prospective comparative study

Archives of Osteoporosis ◽

10.1007/s11657-019-0628-8 ◽

2019 ◽

Vol 14 (1) ◽

Cited By ~ 1

Author(s):

Taewook Kang ◽

Si Young Park ◽

Seok Ha Hong ◽

Jin Hyeok Lee ◽

Soon Hyuck Lee ◽

...

Keyword(s):

Comparative Study ◽

Spinal Fusion ◽

Bone Union ◽

Fusion Surgery ◽

Spinal Fusion Surgery ◽

Local Bone ◽

Prospective Comparative Study

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Revision Rate in Robotic-Guided vs Fluoro-Guided Minimally Invasive Spinal Fusion Surgery: Report from MIS ReFRESH Prospective Comparative Study

The Spine Journal ◽

10.1016/j.spinee.2017.08.178 ◽

2017 ◽

Vol 17 (10) ◽

pp. S255 ◽

Cited By ~ 2

Author(s):

Samuel R. Schroerlucke ◽

Michael Y. Wang ◽

Andrew F. Cannestra ◽

Christopher R. Good ◽

Jae Y. Lim ◽

...

Keyword(s):

Minimally Invasive ◽

Comparative Study ◽

Spinal Fusion ◽

Revision Rate ◽

Fusion Surgery ◽

Spinal Fusion Surgery ◽

Prospective Comparative Study

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Thiazide diuretics and the risk of hip fracture after stroke: a population-based propensity-matched cohort study using Taiwan’s National Health Insurance Research Database

BMJ Open ◽

10.1136/bmjopen-2017-016992 ◽

2017 ◽

Vol 7 (9) ◽

pp. e016992 ◽

Cited By ~ 8

Author(s):

Shu-Man Lin ◽

Shih-Hsien Yang ◽

Hung-Yu Cheng ◽

Chung-Chao Liang ◽

Huei-Kai Huang

Keyword(s):

Cohort Study ◽

Health Insurance ◽

Hip Fracture ◽

National Health Insurance ◽

National Health ◽

Population Based ◽

Research Database ◽

Matched Cohort ◽

Matched Cohort Study

ObjectivesThis study aimed to investigate the association between thiazide use and the risk of hip fracture after stroke.SettingA population-based, propensity-matched cohort study was conducted on the basis of Taiwan’s National Health Insurance Research Database.ParticipantsPatients with newly diagnosed ischaemic stroke between 2000 and 2011 were included. After propensity score matching, 7470 patients were included, of whom 3735 received thiazides and 3735 did not.Outcome measuresHRs for developing hip fractures within 2 years after stroke were calculated using Cox proportional hazards regression model with adjustments for sociodemographic and coexisting medical conditions.ResultsOverall, patients using thiazides after stroke had a lower risk of hip fracture than those not using thiazides (8.5 vs 13.9 per 1000 person-years, adjusted HR=0.64, 95% CI 0.46 to 0.89, p=0.007). Further sensitivity analysis based on the duration of thiazide use revealed that the risk of hip fracture tended to decrease as the duration of exposure of thiazides increased. However, the effect was significant only in patients with long-term use of thiazides (using thiazides for >365 days within 2 years after stroke), with a 59% reduction in the risk of hip fracture when compared with patients not using thiazide (adjusted HR=0.41, 95% CI 0.22 to 0.79, p=0.008).ConclusionsThe long-term use of thiazides is associated with a decreased risk of hip fracture after stroke.

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Effectiveness and safety of recombinant human bone morphogenetic protein-2 for adults with lumbar spine pseudarthrosis following spinal fusion surgery

Bone and Joint Research ◽

10.1302/2046-3758.54.2000418 ◽

2016 ◽

Vol 5 (4) ◽

pp. 145-152 ◽

Cited By ~ 11

Author(s):

P. N. Bodalia ◽

V. Balaji ◽

R. Kaila ◽

L. Wilson

Keyword(s):

Lumbar Spine ◽

Spinal Fusion ◽

Bone Morphogenetic Protein ◽

Human Bone ◽

Bone Morphogenetic Protein 2 ◽

Fusion Surgery ◽

Spinal Fusion Surgery ◽

Morphogenetic Protein ◽

Human Bone Morphogenetic Protein ◽

Recombinant Human Bone

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Internal Fixation, A Reconstructive Spine Surgery: A Remedy of Long-Term Spinal Problems

Bangladesh Journal of Neurosurgery ◽

10.3329/bjns.v9i1.42918 ◽

2019 ◽

Vol 9 (1) ◽

pp. 11-15

Author(s):

Md Aminul Islam ◽

Md Abdul Hye Manik ◽

Rukun Uddin Chowdhury ◽

Md Al Amin Salek ◽

Amir Ali ◽

...

Keyword(s):

Internal Fixation ◽

Spinal Fusion ◽

Spinal Surgery ◽

Spinal Instrumentation ◽

Age And Gender ◽

Fusion Surgery ◽

Excellent Outcome ◽

Spinal Fusion Surgery ◽

And Gender

Background: Spinal instrumentation provides a stable, rigid column that encourages bones to fuse after spinal fusion surgery. Methods: The study was carried out in the Neurosurgery Center, CMH, Dhaka, from 01 January 2013 to July 31 2018. A total of 95 patients were included with unrestricted age and gender, underwent spinal surgery with fixation. Result: Better outcome was observed in spinal surgery with stabilization. Conclusion: Whereas early (within hours) or immediate (within 48 h) stabilization and indirect or direct decompression has excellent outcome, even delayed stabilization of the unstable spine has benefits. Bang. J Neurosurgery 2019; 9(1): 11-15

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Reduced risk of skin cancer and internal malignancies in vitiligo patients: a retrospective population-based cohort study in Taiwan

Scientific Reports ◽

10.1038/s41598-021-99786-9 ◽

2021 ◽

Vol 11 (1) ◽

Author(s):

Yu-Ching Weng ◽

Hsiu J. Ho ◽

Yi-Ling Chang ◽

Yun-Ting Chang ◽

Chun-Ying Wu ◽

...

Keyword(s):

Cohort Study ◽

Cell Carcinoma ◽

Systemic Disease ◽

Population Based ◽

Incidence Rates ◽

Research Database ◽

Hazard Ratios ◽

History Of ◽

Rate Ratios

AbstractThe relationship between cancer and vitiligo has been explored but with inconsistent results. To examine the long-term cancer risk in vitiligo patients, we conducted a retrospective nationwide cohort study. From the National Health Insurance Research Database of Taiwan, a total of 13,824 vitiligo patients were identified and matched with 55,296 reference subjects without vitiligo by age, gender, and propensity score estimated by major comorbidities from 1997 to 2013. Demographic characteristics and comorbidities were compared between these two groups. Incidence rate ratios and hazard ratios (HRs) were calculated to examine cancer risks. The 16-year incidence rates of overall cancers were 621.06 (566.56–675.55) and 726.99 (697.24–756.74) per 100,000 person-years in the vitiligo and reference groups. Patients with vitiligo showed a significantly decreased risk of overall cancers [adjusted HR, 0.85; 95% confidence interval (CI), 0.77 to 0.93, p < 0.001] compared with reference subjects without vitiligo after adjusting for age, sex, comorbidities, and treatments. The risks of basal cell carcinoma (BCC) and squamous cell carcinoma (SCC) were significantly reduced (adjusted HR 0.21, 95% CI 0.11–0.38, p < 0.001), as well as internal malignancies (adjusted HR 0.89, 95% CI 0.81–0.99, p = 0.026). The results were consistent across different subgroups of patients, including male gender, ages more than 40 years, and those receiving long-term systemic disease-modifying antirheumatic drugs and phototherapies. Information related to phenotype, disease duration, vitiligo lesion sites, family history of vitiligo or cancer, occupation, and personal lifestyle was not included in the database. Vitiligo is associated with reduced risks of BCC and SCC, as well as internal malignancies.

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Migraine and subsequent chronic kidney disease risk: a nationwide population-based cohort study

BMJ Open ◽

10.1136/bmjopen-2017-018483 ◽

2017 ◽

Vol 7 (12) ◽

pp. e018483 ◽

Cited By ~ 10

Author(s):

Shuo-Chun Weng ◽

Chia-Lin Wu ◽

Chew-Teng Kor ◽

Ping-Fang Chiu ◽

Ming-Ju Wu ◽

...

Keyword(s):

Chronic Kidney Disease ◽

Cohort Study ◽

Kidney Disease ◽

Disease Risk ◽

Population Based ◽

Interactive Effects ◽

Control Group ◽

Research Database ◽

Control Subjects

ObjectiveWe compared the incidence and risk of chronic kidney disease (CKD) between subjects with new-onset migraine and matched controls without migraine in this large-scale retrospective cohort study.DesignPopulation-based cohort study.Setting8880 subjects with migraine and 503 070 subjects without migraine were enrolled between January 1, 2000 and December 31, 2013, all diagnosed to be without kidney disease. All the participants were registered in the National Health Insurance Research Database.ParticipantsFinally, data from 7156 subjects with migraine and 7156 propensity-score-matched control subjects were analysed.Primary outcome measureWe used Cox proportional hazards regression to estimate adjusted HRs for incident CKD; subgroup analyses were performed to assess the interactive effects of migraine with demographics, comorbidities and long-term medications.ResultsThe incidence of CKD was higher in the migraine group than in the control group. The risk of developing CKD was significantly higher in subjects with migraine than without migraine (P=0.031). Subjects with migraine aged <65 years (age 40–64 (adjusted HR (aHR) 1.35; 95% CI 1.05 to 1.73); age <40 (aHR 1.55; 95% CI 1.02 to 2.36)), with ≥1 comorbid diseases (1–2 diseases (aHR 1.30; 95% CI 1.01 to 1.68); ≥3 diseases (aHR 1.45; 95% CI 1.01 to 2.07)), and not receiving anti-migraine agents (aHR 1.26; 95% CI 1.04 to 1.54) were at a higher risk of developing CKD compared with the control subjects. The interaction between migraine and comorbidities was not significant; age, male gender and long-term use of non-steroidal anti-inflammatory drugs (NSAIDs) were independent risk factors for CKD in subjects with migraine.ConclusionMigraine may be an independent risk factor for CKD. Young subjects with migraine, and those with comorbid conditions or without medical control, are likely to be at higher risk for CKD. Ageing, male sex and NSAIDs tend to have an association with CKD in subjects with migraine.

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