scholarly journals Maternal trauma due to motor vehicle crashes and pregnancy outcomes: a systematic review and meta-analysis

BMJ Open ◽  
2020 ◽  
Vol 10 (10) ◽  
pp. e035562
Author(s):  
Carmen Amezcua-Prieto ◽  
Jennifer Ross ◽  
Ewelina Rogozińska ◽  
Patritia Mighiu ◽  
Virginia Martínez-Ruiz ◽  
...  
Keyword(s):  
Systematic Review ◽  
Latin American ◽  
Maternal Death ◽  
Motor Vehicle ◽  
Meta Analysis ◽  
Population Level ◽  
Motor Vehicle Crashes ◽  
Labour Induction ◽  
Cochrane Central Register ◽  
Vehicle Crashes

ObjectivesTo systematically review and quantify the effect of motor vehicle crashes (MVCs) in pregnancy on maternal and offspring outcomes.DesignSystematic review and meta-analysis of observational data searched from inception until 1 July 2018. Searching was from June to August 2018 in Medline, Embase, Web of Science, Scopus, Latin-American and Caribbean System on Health Sciences Information, Scientific Electronic Library Online, TRANSPORT, International Road Research Documentation, European Conference of Ministers of Transportation Databases, Cochrane Database of Systematic Reviews and Cochrane Central Register.ParticipantsStudies were selected if they focused on the effects of exposure MVC during pregnancy versus non-exposure, with follow-up to verify outcomes in various settings, including secondary care, collision and emergency, and inpatient care.Data synthesisFor incidence data, we calculated a pooled estimate per 1000 women. For comparison of outcomes between women involved and those not involved in MVC, we calculated ORs with 95% CIs. Where possible, we statistically pooled the data using the random-effects model. The quality of studies used in the comparative analysis was assessed with Newcastle–Ottawa Scale.ResultsWe included 19 studies (3 222 066 women) of which the majority was carried out in high-income countries (18/19). In population-level studies of women involved in MVC, maternal death occurred in 3.6 per 1000 (95% CI 0.25–10.42; 3 studies, 12 000 women; Tau=1.77), and fetal death or stillbirth in 6.6 per 1000 (95% CI 3.81–10.12; 8 studies, 47 992 women; I2=92.6%). Pooled incidence of complications per 1000 women involved in MVC was labour induction (276.43), preterm delivery (191.90) and caesarean section (166.65). Compared with women not involved in MVC, those involved had increased odds of placental abruption (OR 1.43, 95% CI 1.27–1.63; 3 studies, 1 500 825 women) and maternal death (OR 202.27; 95% CI 110.60–369.95; 1 study, 1 094 559 women).ConclusionPregnant women involved in MVC were at higher risk of maternal death and complications than those not involved.PROSPERO registration numberCRD42018100788.

Does Obesity Increase the Risk of Injury or Mortality in Motor Vehicle Crashes? A Systematic Review and Meta-Analysis

2011 ◽  
Vol 26 (5) ◽  
pp. 447-460 ◽  
Author(s):  
Ediriweera Desapriya ◽  
Scime Giulia ◽  
Sayed Subzwari ◽  
Dinithi C. Peiris ◽  
Kate Turcotte ◽  
...  
Keyword(s):  
Systematic Review ◽  
Motor Vehicle ◽  
Meta Analysis ◽  
Motor Vehicle Crashes ◽  
Vehicle Crashes ◽  
Risk Of Injury

scholarly journals Risk of Mortality in Association with Pregnancy in Women following Motor Vehicle Crashes: A Systematic Review and Meta-Analysis

2022 ◽  
Vol 19 (2) ◽  
pp. 911
Author(s):  
Ya-Hui Chang ◽  
Ya-Yun Cheng ◽  
Wen-Hsuan Hou ◽  
Yu-Wen Chien ◽  
Chiung-Hsin Chang ◽  
...  
Keyword(s):  
Systematic Review ◽  
Pregnant Women ◽  
Mortality Risk ◽  
Injury Severity ◽  
Motor Vehicle ◽  
Meta Analysis ◽  
Epidemiological Studies ◽  
Motor Vehicle Crashes ◽  
Vehicle Crashes ◽  
Mesh Terms

The aim of the study was to provide a systematic review and meta-analysis of studies examining the association between mortality risk and motor vehicle crashes (MVCs) in pregnant women compared with nonpregnant women. We used relevant MeSH terms to identify epidemiological studies of mortality risk in relation to MVCs from PubMed, Embase, and MEDLINE databases. The Newcastle–Ottawa Scale (NOS) was used for quality assessment. For comparison of mortality from MVCs between pregnant and nonpregnant women, the pooled odds ratios (OR) with 95% confidence intervals (CI) were calculated using a random effects model. The eight studies selected met all inclusion criteria. These studies included 14,120 injured victims who were pregnant at the time of the incident and 207,935 victims who were not pregnant. Compared with nonpregnant women, pregnant women had a moderate but insignificant decrease in mortality risk (pooled OR = 0.68, 95% CI = 0.38–1.22, I2 = 88.71%). Subgroup analysis revealed that the pooled OR significantly increased at 1.64 (95% CI = 1.16–2.33, I2 < 0.01%) for two studies with a similar difference in the mean injury severity score (ISS) between pregnant and nonpregnant women. Future studies should further explore the risk factors associated with MVCs in pregnant women to reduce maternal mortality.

scholarly journals Psychological impact of injuries sustained in motor vehicle crashes: systematic review and meta-analysis

BMJ Open ◽  
2016 ◽  
Vol 6 (9) ◽  
pp. e011993 ◽  
Author(s):  
Ashley Craig ◽  
Yvonne Tran ◽  
Rebecca Guest ◽  
Bamini Gopinath ◽  
Jagnoor Jagnoor ◽  
...  
Keyword(s):  
Systematic Review ◽  
Motor Vehicle ◽  
Meta Analysis ◽  
Psychological Impact ◽  
Motor Vehicle Crashes ◽  
Vehicle Crashes

scholarly journals Use of glucose for pain management in premature neonates: a systematic review and meta-analysis protocol

BMJ Open ◽  
2021 ◽  
Vol 11 (12) ◽  
pp. e052901
Author(s):  
Débora Joyce Duarte Oliveira ◽  
Kleyton Santos Medeiros ◽  
Ayane Cristine Alves Sarmento ◽  
Francisca Jennifer Duarte Oliveira ◽  
Ana Paula Ferreira Costa ◽  
...  
Keyword(s):  
Systematic Review ◽  
Latin American ◽  
Meta Analysis ◽  
Subsequent Development ◽  
Risk Of Bias ◽  
Cochrane Central Register ◽  
Premature Neonates ◽  
Ethical Approval ◽  
Quantitative Synthesis ◽  
Registration Number

IntroductionTherapeutic management of neonatal pain is essential to reduce changes in initial and subsequent development. Although glucose has been shown to be effective in relieving pain, concentrations and dosages remain to be standardised. The objective of this systematic review and meta-analysis is to identify the efficacy of glucose as an analgesic in preterm infants.Methods and analysisThe Web of Science, Science Direct, Scopus, Cochrane Central Register of Controlled Trials, ClinicalTrials.gov, PubMed, Medline, Latin American and Caribbean Health Sciences Literature and Embase databases will be researched for randomised studies published until December 2021. This systematic review and meta-analysis will include studies investigating the use of glucose for pain control in premature neonates. The primary outcome will be pain relief. Three independent reviewers will select the studies and extract the data from original publications. The risk of bias was assessed using the Cochrane risk of bias tool. Data synthesis will be performed using the Review Manager software (RevMan V.5.2.3). We will evaluate heterogeneity based on I2 statistics. In addition, quantitative synthesis will be performed if the included studies are sufficiently homogeneous.Ethics and disseminationEthical approval for the research will not be required for this systematic review. The results of this study will be published in an international journal.Trial registration numberThis protocol was submitted to the International Prospective Register of Systematic Reviews (PROSPERO, number CRD42021236217).

scholarly journals Systemic immunomodulatory treatments for atopic dermatitis: protocol for a systematic review with network meta-analysis

BMJ Open ◽  
2018 ◽  
Vol 8 (8) ◽  
pp. e023061 ◽  
Author(s):  
Aaron Mark Drucker ◽  
Alexandra Ellis ◽  
Zarif Jabbar-Lopez ◽  
Zenas Z N Yiu ◽  
Bernd W M Arents ◽  
...  
Keyword(s):  
Systematic Review ◽  
Atopic Dermatitis ◽  
Adverse Events ◽  
Latin American ◽  
Meta Analysis ◽  
Scientific Journal ◽  
Health Science ◽  
Cochrane Central Register ◽  
Systemic Treatments ◽  
Patient Reported

IntroductionThere are numerous new systemic treatments for atopic dermatitis in various stages of development and most are being compared with placebo rather than active comparators. In order to understand the relative efficacy and safety of existing and new treatments for atopic dermatitis, robust mixed comparisons (ie, direct and indirect) would be beneficial. To address this gap, this protocol describes methods for a systematic review and network meta-analysis of systemic treatments for atopic dermatitis.Methods and analysisWe will update the search of a previous systematic review, including searches of the Cochrane Central Register of Controlled Trials, MEDLINE, Embase, Latin American and Caribbean Health Science Information database and the Global Resource of EczemA Trials database in addition to clinical trial protocol registries. Title, abstract and full paper screening as well as data extraction will be conducted in duplicate by independent researchers. Primary outcomes include efficacy with regards to clinician-reported signs and patient-reported symptoms and safety with regards to withdrawal from treatment due to adverse events and the occurrence of serious adverse events. Secondary outcomes will include change in quality of life and itch severity. Where possible and appropriate, network meta-analysis will be performed for each outcome using a random-effects model within a Bayesian framework. If appropriate, the review will be transitioned to a living review with continuous updating of the analysis.Ethics and disseminationDissemination in a peer-reviewed scientific journal is planned.PROSPERO registration numberCRD42018088112; Pre-results.

The impact of policies regulating alcohol trading hours and days on specific alcohol-related harms: a systematic review

2017 ◽  
Vol 24 (1) ◽  
pp. 94-100 ◽  
Author(s):  
Diana C Sanchez-Ramirez ◽  
Donald Voaklander
Keyword(s):  
Systematic Review ◽  
Emergency Department ◽  
English Language ◽  
Motor Vehicle ◽  
Emergency Department Visits ◽  
Motor Vehicle Crashes ◽  
Vehicle Crashes ◽  
The Impact ◽  
Alcohol Related Harm ◽  
Related Harm

BackgroundEvidence supports the expectation that changes in time of alcohol sales associate with changes in alcohol-related harm in both directions. However, to the best of our knowledge, no comprehensive systematic reviews had examined the effect of policies restricting time of alcohol trading on specific alcohol-related harms.ObjectiveTo compile existing evidence related to the impact of policies regulating alcohol trading hours/days of on specific harm outcomes such as: assault/violence, motor vehicle crashes/fatalities, injury, visits to the emergency department/hospital, murder/homicides and crime.MethodsSystematic review of literature studying the impact of policies regulation alcohol trading times in alcohol-related harm, published between January 2000 and October 2016 in English language.ResultsResults support the premise that policies regulating times of alcohol trading and consumption can contribute to reduce injuries, alcohol-related hospitalisations/emergency department visits, homicides and crime. Although the impact of alcohol trading policies in assault/violence and motor vehicle crashes/fatalities is also positive, these associations seem to be more complex and require further study.ConclusionEvidence suggests a potential direct effect of policies that regulate alcohol trading times in the prevention of injuries, alcohol-related hospitalisations, homicides and crime. The impact of these alcohol trading policies in assault/violence and motor vehicle crashes/fatalities is less compelling.

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