Aspiration risk in relation to Glasgow Coma Scale score and clinical parameters in patients with severe acute alcohol intoxication: a single-centre, retrospective study

ObjectivesIn alcohol intoxicated patients, the decision for or against airway protection can be challenging and is often based on the Glasgow Coma Scale (GCS). Primary aim of this study was to analyse the aspiration risk in relation to the GCS score and clinical parameters in patients with severe acute alcohol monointoxication. Secondary aim was the association between the blood alcohol level and the GCS score.SettingSingle-centre, retrospective study of alcoholised patients admitted to a German intensive care unit between 2006 and 2020.ParticipantsA total of n=411 admissions were eligible for our analysis.Clinical measures and analysisThe following data were extracted: age, gender, admission time, blood alcohol level, blood glucose level, initial GCS score, GCS score at admission, vital signs, clinical signs of aspiration and airway management measures. The empirical distribution of continuous and categorical data was calculated. Binary multivariable logistic regression analysis was used to identify possible risk factors for aspiration.ResultsThe mean age was 35 years. 72% (n=294) of the admissions were male. The blood alcohol level (mean 2.7 g/L±1.0, maximum 5.9 g/L) did not correlate with the GCS score but with the age of the patient. In univariate analysis, the aspiration risk correlated with blood alcohol level, age, GCS score, oxygen saturation, respiratory rate and blood glucose level and was significantly higher in male patients, on vomiting, and in patients requiring airway measures. Aspiration rate was 45% (n=10) in patients without vs 6% (n=3) in patients with preserved protective reflexes (p=0.0001). In the multivariate analysis, only age and GCS score were significantly associated with the risk of aspiration.ConclusionAlthough in this single-centre, retrospective study the aspiration rate in severe acute alcohol monointoxicated patients correlates with GCS and protective reflexes, the decision for endotracheal intubation might rather be based on the presence of different risk factors for aspiration.

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Outcome of pinning in patients with slipped capital femoral epiphysis: risk factors associated with avascular necrosis, chondrolysis, and femoral impingement

Journal of International Medical Research ◽

10.1177/0300060517731683 ◽

2017 ◽

Vol 46 (6) ◽

pp. 2120-2127 ◽

Cited By ~ 4

Author(s):

Alexandru Ulici ◽

Madalina Carp ◽

Iulia Tevanov ◽

Catalin Alexandru Nahoi ◽

Alin Gabriel Sterian ◽

...

Keyword(s):

Risk Factors ◽

Retrospective Study ◽

Avascular Necrosis ◽

Slipped Capital Femoral Epiphysis ◽

Normal Weight ◽

Single Centre ◽

Factors Associated ◽

Hip Impingement ◽

Α Angle

Objective This study aimed to assess the principal risk factors that could lead to the most common long-term complications of slipped capital femoral epiphysis, such as avascular necrosis, chondrolysis, and hip impingement. Methods We conducted a single-centre, retrospective study and evaluated patients (70 patients, 81 hips) who were treated for slipped capital femoral epiphysis from 2010 to 2015 and who underwent pinning. We measured the severity of displacement radiologically using the Southwick angle. Postoperative radiographs were evaluated for the most frequent long-term complications of avascular necrosis (AVN), chondrolysis, and femoral acetabular impingement (FAI). Results We found seven cases of AVN, 14 cases of chondrolysis, and 31 hips had an α angle of 60°. Sex, ambulation, and symptoms did not affect development of these complications. Patients with a normal weight were almost two times more likely to develop FAI. Patients with moderate and severe slips had a similar percentage of AVN. In severe slips, 85.7% of patients had an α angle higher than 60°. Conclusions This study shows that severe slips have a higher risk of developing AVN and hip impingement. Every patient who suffers from SCFE (even the mildest forms) should be regularly checked for FAI.

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Incidence and risk factors for poor perioperative blood glucose management in patients with diabetic foot: a retrospective study

Annals of Palliative Medicine ◽

10.21037/apm-21-3095 ◽

2021 ◽

Vol 0 (0) ◽

pp. 0-0

Author(s):

Xia Chen ◽

Meifang Wu ◽

Qin Hu ◽

Xiu Cheng

Keyword(s):

Risk Factors ◽

Retrospective Study ◽

Blood Glucose ◽

Diabetic Foot ◽

Glucose Management

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Endophthalmitis and severe blebitis following trabeculectomy. Epidemiology and risk factors; a single-centre retrospective study

Acta Ophthalmologica ◽

10.1111/aos.12257 ◽

2013 ◽

Vol 92 (5) ◽

pp. 426-431 ◽

Cited By ~ 24

Author(s):

Örjan Wallin ◽

Abdullah M. Al-ahramy ◽

Mats Lundström ◽

Per Montan

Keyword(s):

Risk Factors ◽

Retrospective Study ◽

Single Centre

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Positive compared with negative margins in a single-centre retrospective study on 3957 consecutive excisions of basal cell carcinomas. Associated risk factors and preferred surgical management

Journal of Plastic Surgery and Hand Surgery ◽

10.3109/2000656x.2013.800526 ◽

2013 ◽

Vol 48 (1) ◽

pp. 38-43 ◽

Cited By ~ 23

Author(s):

D. Codazzi ◽

J. Van Der Velden ◽

M. Carminati ◽

S. Bruschi ◽

M. A. Bocchiotti ◽

...

Keyword(s):

Risk Factors ◽

Retrospective Study ◽

Surgical Management ◽

Basal Cell ◽

Single Centre ◽

Basal Cell Carcinomas ◽

Associated Risk Factors

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P-120 Risk factors in myelodysplastic syndromes (MDS): A single centre retrospective study

Leukemia Research ◽

10.1016/s0145-2126(13)70168-1 ◽

2013 ◽

Vol 37 ◽

pp. S77-S78

Author(s):

S. Improta ◽

M.R. Villa ◽

A. Gagliardi ◽

P. Della Cioppa ◽

A. Lucania ◽

...

Keyword(s):

Risk Factors ◽

Retrospective Study ◽

Myelodysplastic Syndromes ◽

Single Centre

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Perineal wound complication risk factors and effects on survival after abdominoperineal resection of rectal cancer: a single-centre retrospective study

International Journal of Colorectal Disease ◽

10.1007/s00384-021-03840-x ◽

2021 ◽

Author(s):

Chao Wang ◽

Junyu You ◽

Zhanlong Shen ◽

Kewei Jiang ◽

Zhidong Gao ◽

...

Keyword(s):

Risk Factors ◽

Rectal Cancer ◽

Retrospective Study ◽

Abdominoperineal Resection ◽

Perineal Wound ◽

Wound Complication ◽

Single Centre ◽

Perineal Wound Complication ◽

Complication Risk

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Analysis of risk factors of delayed encephalopathy after acute carbon monoxide poisoning

Journal of Neurorestoratology ◽

10.26599/jnr.2021.9040020 ◽

2021 ◽

Vol 9 (4) ◽

pp. 245-254

Author(s):

He Gao ◽

Lifang Xu ◽

Bo Zhou ◽

Lin Li ◽

Hui Sun ◽

...

Keyword(s):

Risk Factors ◽

Carbon Monoxide ◽

Logistic Regression ◽

Blood Glucose ◽

Roc Curve ◽

Carbon Monoxide Poisoning ◽

Cranial Ct ◽

History Of ◽

Gcs Score ◽

Delayed Encephalopathy

Objective:To analyze the risk factors of delayed encephalopathy in patients with acute carbon monoxide poisoning (DEACMP) and to investigate the clinical significance and clinical value.Methods:The baseline data from 68 patients admitted in the 981st Hospital of Chinese People’s Liberation Army Joint Logistics Support Force were collected, including sex, age, Glasgow Coma Scale (GCS), history of smoking/drinking, history of DEACMP. Laboratory examination records including cranial CT/MRI, cervical vascular color ultrasonography, cardiac color ultrasonography, blood biochemical markers, blood routine, and blood coagulation function were also collected. Additionally, patients were followed-up visited at 1 month and 6 months. Patients were divided into either the DEACMP group or the NDEACMP group according to the occurrence of DEACMP. The risk factors of DEACMP were identified by univariate and logistic regression analyses. The area under the curve (AUC), sensitivity, and specificity of each index were compared by the receiver operating characteristic (ROC) curve.Results:Among the 68 patients, 13 patients suffered from DEACMP with an incidence of 19.1%. Univariate analysis indicated that there were statistically significant differences in patients’ age, blood glucose, blood glucose/potassium, GCS scores, abnormal cranial CT/MRI, and coma time more than 4 h (P < 0.05). Logistic regression analysis showed that B, SE, Wald, df, P, Exp (B) of GCS score were -0.489, 0.208, 5.55, 1, 0.018 and 0.634, respectively. Overall, GCS score is correlated with DEACMP’s occurrence. ROC curve analysis showed that the sensitivity, specificity, and the AUC of GCS scores were 0.769, 0.873 and 0.843, respectively. The AUC of the indices in descending order are: GCS score, blood glucose, blood glucose/potassium and age.Conclusion:GCS score, blood glucose, blood glucose/potassium, and age are useful predictive factors for the occurrence of DEACMP. Among these, GCS score is the most significant predictive factor.

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Aetiology of chronic kidney disease and risk factors for disease progression in Chinese subjects: A single‐centre retrospective study in Beijing

Nephrology ◽

10.1111/nep.13714 ◽

2020 ◽

Vol 25 (9) ◽

pp. 714-722 ◽

Cited By ~ 1

Author(s):

Zhun Sui ◽

Jiemin Wang ◽

Claudia Cabrera ◽

Jia Wei ◽

Mi Wang ◽

...

Keyword(s):

Risk Factors ◽

Chronic Kidney Disease ◽

Retrospective Study ◽

Kidney Disease ◽

Disease Progression ◽

Single Centre ◽

Chinese Subjects

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A retrospective study of risk factors for calf venous thrombosis in patients with cerebral hemorrhage

10.21203/rs.3.rs-90060/v1 ◽

2020 ◽

Author(s):

Xiaogang Gao ◽

Yi Li ◽

Dongzhe Hou

Keyword(s):

Risk Factors ◽

Logistic Regression ◽

Retrospective Study ◽

Muscle Strength ◽

Venous Thrombosis ◽

Cerebral Hemorrhage ◽

Clinical Manifestations ◽

Affected Side ◽

Gcs Score ◽

D Dimer

Abstract Purpose：To investigate the risk factors for calf venous thrombosis in patients with cerebral hemorrhage, so as to provide a reference for customized clinical decision.Methods：396 intracerebral hemorrhage (ICH) patients were enrolled in this retrospective study from January 2017 to December 2019. Risk factors and predictors of occurrence for Muscle calf venous thrombosis (MCVT) were summarized and analyzed by Chi-square test and logistic regression analysis.Results: 128 ICH patients with MCVT and 268 without ones were included. Demographic features comparison showed that ICH with MCVT patients showed older average age than those without ones (p=0.039). Co-morbid diseases analysis showed that patients with MCVT tend to complicate with Diabetes Mellitus (DM) (p=0.040). The comparison of laboratory examinations showed serum level of glucose (p=0.011), Fibrinogen (p=0.046) and D-Dimer (p=0.007) was significantly different. For clinical manifestations, the coma degree (GCS score) and muscle strength level were related to occurring of MCVT. Multivariate logistic regression identified higher age (OR=1.036, 95%CI =1.009-1.064, P= 0.008), higher D-Dimer level (OR=2.379, 95%CI =1.338-4.231, P= 0.003), low GCS (OR=0.932, 95%CI =0.868-0.998, P= 0.044) and lower affected side muscle strength (0-3 grade) (OR=1.624, 95%CI =1.009-2.614, P= 0.046) will predict higher incidence of MCVT in ICH patients.Conclusion: According to our study, higher age, higher D-Dimer level, lower GCS score and lower affected side muscle strength were associated with higher incidence of MCVT in ICH patients. Clinical doctors should pay more attention to prevent MCVT in ICH patients which coincide with those risk factors.

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