Identification of tablets and capsules

1965 ◽  
Vol 3 (14) ◽  
pp. 53-54
Keyword(s):  
General Practitioner ◽  
General Practitioners ◽  
The Other ◽  
List Type ◽  
Acute Overdose ◽  
Record Card ◽  
The One

Doctors may need to identify an unknown treatment for several reasons: After an acute overdose the drug must be rapidly identified without waiting for time-consuming analysis. In hospital this emergency is not rare.Liaison between the general practitioner and hospital is often imperfect and either party may be unclear about the treatment the patient is receiving from the other. This is much commoner than overdosage.Most general practitioners at some time participate in an arrangement that involves a deputy. One doctor may then see a colleague’s patient without immediate access to the record card. Uncertainty about treatment in such circumstances is experienced by every general practitioner and many consultants seeing patients referred to them.Many patients take more than one kind of preparation: if one is to be changed, or its dosage altered, the patient must be certain which is the one affected.

HOMOLOGOUS RADIOIMMUNOASSAY OF THYROTROPHIN IN RAT PLASMA

1974 ◽  
Vol 76 (3) ◽  
pp. 495-505 ◽  
Author(s):  
J. David Kieffer ◽  
Bruce D. Weintraub ◽  
Walter Baigelman ◽  
Susan Leeman ◽  
Farahe Maloof
Keyword(s):  
Zero Point ◽  
Rat Plasma ◽  
Cross Reaction ◽  
The Other ◽  
Male Rats ◽  
List Type ◽  
Specific Effects ◽  
The One ◽  
Bovine Tsh ◽  
Tsh Levels

ABSTRACT An homologous radioimmunoassay (RIA) using the highly purified rat thyrotrophin (TSH) and anti-rat TSH recently made available by NIAMDD is described in detail. Evidence that the assay measures TSH and only TSH includes the following: Treatment of rats with TSH-releasing hormone (TRH) caused a significant increase (averaging 12-fold) and treatment with T4, a significant decrease (averaging 4.5-fold), in plasma TSH. Points for TSH standards and those for dilutions of plasma from TRH-treated rats fell on the same line, and regression lines calculated separately for standards and dilutions of plasma did not depart significantly from parallelism. At 14 days after gonadectomy of male rats, a time when plasma LH and FSH levels are known to be high, the assay showed no increase in plasma TSH. Moreover, reduction of plasma TSH levels by T4 was as great in gonadectomized rats as in controls. Assay of rat LH, rat FSH and rat prolactin, in 7 concentrations each, showed that cross-reaction averaged less than 1 % in all cases. Other workers have calculated values greater than 1 % for TSH contamination of rat LH and FSH. The slopes of regression lines for the 3 hormones tested for cross-reaction did not differ significantly from the slope for TSH standards. This result strengthens the hypothesis that the apparent slight cross-reactions are due to TSH contamination. Findings for T4-treated rats and saline-treated controls show that the homologous RIA is more sensitive than previous, heterologous assays: In previous studies, plasma TSH levels of most or all of rats treated with T4 were not clearly greater than zero. By contrast, in the homologous RIA reported here, values for such rats did not overlap the range of the zero point on the one hand, nor the range for saline-treated controls on the other. Thus, distinct ranges were defined for both normal and low TSH levels. In view of the 1:20 final dilution of plasma during assay, it does not seem likely that non-specific effects of plasma were primarily responsible for the low TSH values of T4-treated rats. Additionally, the useful range of the homologous assay (about 200-fold) is greater than that of earlier assays (about 70-fold, or less). Finally, the use of highly purified rat TSH for standards has avoided inconsistencies previously encountered with bovine TSH standards.

scholarly journals Application of the Electrical (Geophysical) Method for the Identification of the Sealed Bevel in the Coastal Region of Walidia Province of el Jadida – Morocco

2018 ◽  
Vol 37 ◽  
pp. 05003
Author(s):  
H. Elfjiji ◽  
A. Boukdir ◽  
A. Zitouni
Keyword(s):  
Salt Water ◽  
Coastal Region ◽  
Upper Jurassic ◽  
The Other ◽  
List Type ◽  
Mineral Salts ◽  
Marine Invasion ◽  
Roof Structure ◽  
Other Hand ◽  
The One

The Walidia area knows a great development of agricultural, industrial, maritime activities and a very great demographic expansion. This development is accompanied by a growing demand for water. On the other hand, any intense abstraction of fresh water at a coastal aquifer capture field causes a decrease in groundwater flow and a lowering of the piezometric surface. There is therefore a danger of advancing towards the land of the saltwater bevel and salinization of groundwater which is gradually loaded into mineral salts and can reach abnormally high levels. This work deals with the application of geophysics by electrical sounding method to the in-depth study of the freshwater-salt water interface (salted bevel) on the one hand and the study of the lateral and vertical evolution of the geometry of the different aquifers. The principle of the method is, when performing an electrical survey, to research how varies, at a given point on the surface, the resistivity of the subsoil vertically. For this one executes in a same place a succession of measurements, increasing each time the dimensions of the device and thus the depth of investigation which is proportional to them. At this site, we explore a slice of ground increasingly thick and thus highlights the changes in geological constitution along the vertical. The electrical soundings were carried out with the classic Schlumberger device. The interpretation and the exploitation of the data of the electric soundings carried out made it possible to : Follow the evolution of the salted bevel roof, Draw the upstream limit (marine invasion) of salted bevel Hauterivian, on the one hand, and Valanginian and Jurassic on the other hand, Follow the roof structure of Dridrat limestone (Hauterivien) and limestones of Valanginien and Upper Jurassic, Draw the map of the marl roof of Safi (Hauterivian) constituting the impermeable substratum of Dridrat limestones.

Breeding

1939 ◽  
Vol 12 (1-2) ◽  
pp. 27-55
Keyword(s):  
The Other ◽  
List Type ◽  
Type Number ◽  
Other Hand ◽  
Average Production ◽  
Eye Colour ◽  
White Leghorns ◽  
The One ◽  
Different Strains

The connection between the Colour of the Eyes, the Mortality, and the Production of White Leghorns. Het Verband tusschen de oogkleur van Witte Leghorns en de Herfte en de productie. Dr. J. B. van der Meulen. Landbouwkundig Tijdschrift, Vol. 50, 1938, p. 868.An investigation, in which 406 White Leghorns of two different strains were used, on the connection between the colour of the eyes of normal healthy pullets at the beginning of the laying period on the one hand and the production and mortality during the pullet year on the other hand, led to the following conclusions:—1.The mortality amongst hens with abnormal colour of the eyes, (brown-grey and/or blue) is considerably higher than that amongst birds with normal orange coloured eyes, and the production of the former is on the average lower than that of the latter.2.Birds with one normal and one abnormal coloured eyes, correspond to birds with normal coloured eyes as far as mortality is concerned, but their average production resembles more than that of birds with two abnormal eyes.3.Not only an abnormal eye colour but also an abnormal shape of the pupil seems to point to higher mortality and the highest mortality is probable amongst birds which have both an abnormal colour, as well as an abnormal shape of the pupil.

Physical Types and Their Relations to Psychotic Types

1940 ◽  
Vol 86 (363) ◽  
pp. 602-623 ◽  
Author(s):  
J. I. Cohen
Keyword(s):  
The Other ◽  
List Type ◽  
Type Number ◽  
The One

The object of this paper is to test the following two hypotheses: 1.That the physique of female adults can be regarded as the resultant of two independent modes of variation, one determining differences in size or bulk, and the other determining differences in proportion or type.2.That a relation exists between schizophrenia and manic-depres sion, on the one hand, and differences in physical proportion or type, on the other.

Smale solenoid attractors and affine Hirsch foliations

2017 ◽  
Vol 39 (2) ◽  
pp. 531-553 ◽  
Author(s):  
BIN YU
Keyword(s):  
Close Relationships ◽  
Orbit Space ◽  
Conjugacy Classes ◽  
The Other ◽  
List Type ◽  
Orbit Spaces ◽  
Stable And Unstable Manifolds ◽  
Unstable Manifolds ◽  
The One ◽  
Structurally Stable

The main purpose of this paper is to study north–south Smale solenoid diffeomorphisms on$3$-manifolds by using affine Hirsch foliations. A north–south Smale solenoid diffeomorphism$f$on a closed$3$-manifold$M$is a diffeomorphism whose non-wandering set is composed of a Smale solenoid attractor$\unicode[STIX]{x1D6EC}_{a}$and a Smale solenoid repeller$\unicode[STIX]{x1D6EC}_{r}$. The key observation is that a north–south Smale solenoid diffeomorphism$f$automatically induces two non-isotopically leaf-conjugate affine Hirsch foliations${\mathcal{H}}^{s}$and${\mathcal{H}}^{u}$on the orbit space of the wandering set of$f$(abbreviated to thewandering orbit spaceof$f$) by the stable and unstable manifolds of$\unicode[STIX]{x1D6EC}_{a}$and$\unicode[STIX]{x1D6EC}_{r}$, respectively. Under this viewpoint, we build some close relationships between north–south Smale solenoid diffeomorphisms and Hirsch manifolds (the closed$3$-manifolds admitting two non-isotopically leaf-conjugate affine Hirsch foliations).∙On the one hand, the union of the wandering orbit spaces is nearly in one-to-one correspondence with the union of Hirsch manifolds.∙On the other hand, surprisingly, the topology of the wandering orbit space (Hirsch manifold) is nearly a complete invariant of north–south Smale solenoid diffeomorphisms up to semi-global conjugacy.Moreover, as applications, we consider several more concrete questions. For instance, we prove that every diffeomorphism in many semi-global conjugacy classes of north–south Smale solenoid diffeomorphisms are not structurally stable.

scholarly journals Az epidermolysis bullosa szájüregi tünetei és annak ellátása

2017 ◽  
Vol 158 (40) ◽  
pp. 1577-1583 ◽  
Author(s):  
Balázs Károly Barna ◽  
Gabriella Eördegh ◽  
Gyula Iván ◽  
József Piffkó ◽  
Pálma Silló ◽  
...  
Keyword(s):  
General Practitioners ◽  
Epidermolysis Bullosa ◽  
Dental Treatment ◽  
Daily Basis ◽  
The Other ◽  
International Literature ◽  
Prevention Strategies ◽  
Research Findings ◽  
The One

Abstract: The aim of this comprehensive article is to provide guidelines for the daily treatment of patients with epidermolysis bullosa, thus contributing to the attainment of their higher quality of life through the improvement of their oral health. Moreover, it is our intention to facilitate the cooperation among Hungarian general practitioners, dermatologists and dentists. Relying on recent research findings of the international literature, we intend to help general practitioners or dermatologists treating epidermolysis bullosa patients on a daily basis by identifying symptoms that require consulting an oral professional on the one hand, and to present the most important prevention strategies and further treatments advised for dentists on the other. Focusing on various aspects of dental treatment, we specify how a dentist can treat the patient without causing additional wounds or pain, and what kinds of therapy are justified by this approach. Orv Hetil. 2017; 158(40): 1577–1583.

Note on Selection of Coordinate Systems for Geodynamics

1975 ◽  
Vol 26 ◽  
pp. 395-407
Author(s):  
S. Henriksen
Keyword(s):  
Sea Level ◽  
The Other ◽  
Coordinate Systems ◽  
Mean Sea Level ◽  
The Earth ◽  
The One ◽  
Static Systems ◽  
Selection Of

The first question to be answered, in seeking coordinate systems for geodynamics, is: what is geodynamics? The answer is, of course, that geodynamics is that part of geophysics which is concerned with movements of the Earth, as opposed to geostatics which is the physics of the stationary Earth. But as far as we know, there is no stationary Earth – epur sic monere. So geodynamics is actually coextensive with geophysics, and coordinate systems suitable for the one should be suitable for the other. At the present time, there are not many coordinate systems, if any, that can be identified with a static Earth. Certainly the only coordinate of aeronomic (atmospheric) interest is the height, and this is usually either as geodynamic height or as pressure. In oceanology, the most important coordinate is depth, and this, like heights in the atmosphere, is expressed as metric depth from mean sea level, as geodynamic depth, or as pressure. Only for the earth do we find “static” systems in use, ana even here there is real question as to whether the systems are dynamic or static. So it would seem that our answer to the question, of what kind, of coordinate systems are we seeking, must be that we are looking for the same systems as are used in geophysics, and these systems are dynamic in nature already – that is, their definition involvestime.

Stories and the Self

2020 ◽  
Vol 32 (2) ◽  
pp. 47-58 ◽  
Author(s):  
Stefan Krause ◽  
Markus Appel
Keyword(s):  
Meta Analysis ◽  
The Self ◽  
The Other ◽  
Lower Degree ◽  
Contrast Effects ◽  
Self Perception ◽  
Self Perceptions ◽  
Other Hand ◽  
The One ◽  
Implicit And Explicit

Abstract. Two experiments examined the influence of stories on recipients’ self-perceptions. Extending prior theory and research, our focus was on assimilation effects (i.e., changes in self-perception in line with a protagonist’s traits) as well as on contrast effects (i.e., changes in self-perception in contrast to a protagonist’s traits). In Experiment 1 ( N = 113), implicit and explicit conscientiousness were assessed after participants read a story about either a diligent or a negligent student. Moderation analyses showed that highly transported participants and participants with lower counterarguing scores assimilate the depicted traits of a story protagonist, as indicated by explicit, self-reported conscientiousness ratings. Participants, who were more critical toward a story (i.e., higher counterarguing) and with a lower degree of transportation, showed contrast effects. In Experiment 2 ( N = 103), we manipulated transportation and counterarguing, but we could not identify an effect on participants’ self-ascribed level of conscientiousness. A mini meta-analysis across both experiments revealed significant positive overall associations between transportation and counterarguing on the one hand and story-consistent self-reported conscientiousness on the other hand.

Radioimmunotherapy for treatment of acute myeloid leukaemia and myelodysplastic syndrome

2005 ◽  
Vol 44 (03) ◽  
pp. 107-117
Author(s):  
R. G. Meyer ◽  
W. Herr ◽  
A. Helisch ◽  
P. Bartenstein ◽  
I. Buchmann
Keyword(s):  
Acute Myeloid Leukaemia ◽  
Myeloid Leukaemia ◽  
Primary Tumour ◽  
The Other ◽  
Haematopoietic Stem Cell ◽  
Other Hand ◽  
Primary Reduction ◽  
The One ◽  
Acute Myeloid

SummaryThe prognosis of patients with acute myeloid leukaemia (AML) has improved considerably by introduction of aggressive consolidation chemotherapy and haematopoietic stem cell transplantation (SCT). Nevertheless, only 20-30% of patients with AML achieve long-term diseasefree survival after SCT. The most common cause of treatment failure is relapse. Additionally, mortality rates are significantly increased by therapy-related causes such as toxicity of chemotherapy and complications of SCT. Including radioimmunotherapies in the treatment of AML and myelodyplastic syndrome (MDS) allows for the achievement of a pronounced antileukaemic effect for the reduction of relapse rates on the one hand. On the other hand, no increase of acute toxicity and later complications should be induced. These effects are important for the primary reduction of tumour cells as well as for the myeloablative conditioning before SCT.This paper provides a systematic and critical review of the currently used radionuclides and immunoconjugates for the treatment of AML and MDS and summarizes the literature on primary tumour cell reductive radioimmunotherapies on the one hand and conditioning radioimmunotherapies before SCT on the other hand.

Postmarketing Surveillance Based on Electronic Patient Records: The IPCI Project

1999 ◽  
Vol 38 (04/05) ◽  
pp. 339-344 ◽  
Author(s):  
J. van der Lei ◽  
B. M. Th. Mosseveld ◽  
M. A. M. van Wijk ◽  
P. D. van der Linden ◽  
M. C. J. M. Sturkenboom ◽  
...  
Keyword(s):  
General Practitioner ◽  
General Practitioners ◽  
Validation Studies ◽  
Resource Planning ◽  
Routine Practice ◽  
Patient Records ◽  
Postmarketing Surveillance ◽  
Electronic Patient Records ◽  
Use Of Data ◽  
Data Requirements

AbstractResearchers claim that data in electronic patient records can be used for a variety of purposes including individual patient care, management, and resource planning for scientific research. Our objective in the project Integrated Primary Care Information (IPCI) was to assess whether the electronic patient records of Dutch general practitioners contain sufficient data to perform studies in the area of postmarketing surveillance studies. We determined the data requirements for postmarketing surveil-lance studies, implemented additional software in the electronic patient records of the general practitioner, developed an organization to monitor the use of data, and performed validation studies to test the quality of the data. Analysis of the data requirements showed that additional software had to be installed to collect data that is not recorded in routine practice. To avoid having to obtain informed consent from each enrolled patient, we developed IPCI as a semianonymous system: both patients and participating general practitioners are anonymous for the researchers. Under specific circumstances, the researcher can contact indirectly (through a trusted third party) the physician that made the data available. Only the treating general practitioner is able to decode the identity of his patients. A Board of Supervisors predominantly consisting of participating general practitioners monitors the use of data. Validation studies show the data can be used for postmarketing surveillance. With additional software to collect data not normally recorded in routine practice, data from electronic patient record of general practitioners can be used for postmarketing surveillance.

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