Preoperative skin cleansing with chlorhexidine-alcohol reduces surgical site infection after clean-contaminated surgery compared with povidone-iodine

This chapter summarizes the landmark trial that examined, in patients undergoing clean-contaminated surgery, how chlorhexidine–alcohol scrub compared to povidone–iodine scrub and paint in terms of infection rates. The trial included patients who were undergoing colorectal, small intestinal, gastroesophageal, biliary, thoracic, gynecologic, or urologic operations without substantial spillage or unusual contamination. Chlorhexidine reduced the rate of any surgical infection as well as that of superficial incisional infection, but no difference was observed for deep incisional infections, organ space infection, and sepsis from surgical-site infection.

Download Full-text

Efficacy of Chlorhexidine Alcohol over Aqueous Povidone Iodine in Prevention of Surgical Site Infection

International Journal of Science and Research (IJSR) ◽

10.21275/v4i12.nov152442 ◽

2015 ◽

Vol 4 (12) ◽

pp. 1966-1969

Keyword(s):

Surgical Site Infection ◽

Povidone Iodine ◽

Site Infection

Download Full-text

Study of efficacy of short course peri-operative antibiotics in clean contaminated surgeries

International Surgery Journal ◽

10.18203/2349-2902.isj20173207 ◽

2017 ◽

Vol 4 (8) ◽

pp. 2455

Author(s):

Shivakumar C. R. ◽

Mohammad Fazelul Rahman Shoeb ◽

Anil Reddy Pinate

Keyword(s):

Surgical Site Infection ◽

Infection Rate ◽

Surgical Site Infections ◽

Cost Effective ◽

Site Infection ◽

Medical Sciences ◽

Short Course ◽

Perioperative Antibiotics ◽

Clean Contaminated ◽

Hospital Acquired

Background: Surgical site infection is a one of the most common postoperative complication and causes significant postoperative morbidity and mortality. WHO described Hospital acquired infections as one of the major infectious diseases having huge economic impact. Perioperative antibiotics constitute the bulk of antimicrobial consumption in any hospital. We need to adapt the policies that decrease the incidence of postoperative wound infection.Methods: Patients undergoing elective surgeries for clean contaminated cases for various causes from 15th May 2014 to 15th June 2017 under Surgical 1st Unit of District hospital Gulbarga (Affiliated to Gulbarga Institute of Medical Sciences, Gulbarga) are included in our study. During this period, a total of 216 patients participated, of which 145 were males and 71 were females. Patients received two doses of perioperative antibiotics, first dose before surgery and second dose after surgery, 12 hours apart during this period.Results: In this study, surgical site infection rate is 2.3% in clean-contaminated surgeries.Conclusions: The findings indicate that a short course of perioperative antibiotics where in first dose is given 30 minutes to one hour before surgery and second dose is given 12 hours after surgery are sufficient and efficacious as infection rate is acceptable (1%-3%).Infection rate in our study was 2.3%. It is cost-effective as well for prevention of surgical site infections in clean-contaminated surgeries in Indian surgical setup.

Download Full-text

COMPARATIVE STUDY OF PRE-CAESAREAN VAGINAL WASH WITH 5% POVIDONE – IODINE SOLUTION VERSUS NO WASH IN PREVENTING POSTOPERATIVE INFECTION.

10.36106/ijsr/8030301 ◽

2020 ◽

pp. 44-46

Author(s):

Sonali Deshpande ◽

Shrinivas Gadappa ◽

Dhanashree Lahane ◽

Sandeep Mannikatti

Keyword(s):

Surgical Site Infection ◽

Wound Infection ◽

Povidone Iodine ◽

Prophylactic Antibiotic ◽

Control Group ◽

Site Infection ◽

Iodine Solution ◽

Interventional Group ◽

Vaginal Wash ◽

Povidone Iodine Solution

Objective: To evaluate the efficacy of pre-cesarean vaginal wash using 5% Povidone Iodine solution on rate of post-cesarean section (CS) surgical site infection and compared with No swabbing. Method: A Prospective Randomized controlled Trial was conducted in department of Obstetrics and Gynecology in Government medical college, Aurangabad. In interventional group, vaginal swabbing with a gauze pieces impregnated with 5% Povidone Iodine solution was done for 30 seconds. The swabbing of vagina was not performed in cases assigned to control group, however the standard surgical preparation of abdomen was done in a usual manner for both group. All subject received prophylactic antibiotic cover. Collected data was complied in pre-designed proforma and analysis was done using SPSS 15. Result: The risk of post operative fever and wound infection was significantly reduced in interventional group. No measure difference was noted in seroma and composite wound infection. Also less duration of hospital stay in interventional group was noted. No adverse effect of use of Povidone iodine was reported in the interventional group. Conclusion: Vaginal swabbing with 5% Povidone-iodine pre- LSCS is inexpensive and simple intervention even for low resource setting to decrease surgical site infection.

Download Full-text

A Randomized Control Trial Comparing Transparent Film Dressings and Conventional Occlusive Dressings for Elective Surgical Procedures

Open Access Macedonian Journal of Medical Sciences ◽

10.3889/oamjms.2019.809 ◽

2019 ◽

Vol 7 (17) ◽

pp. 2844-2850 ◽

Cited By ~ 2

Author(s):

Moushira Hosny Ezzelarab ◽

Omar Nouh ◽

Ahmed Nabil Ahmed ◽

Mervat Gaber Anany ◽

Nevine Gamal El Rachidi ◽

...

Keyword(s):

Surgical Site Infection ◽

Infection Rate ◽

Financial Burden ◽

P Value ◽

Diabetic Patients ◽

Site Infection ◽

Surgical Site Infection Rate ◽

Gauze Dressing ◽

Clean Contaminated ◽

The Impact

BACKGROUND: Surgical site infection is one of the major health-care-associated problems causing substantial morbidity and mortality and constituting a financial burden on hospitals as well. The wound management is one of the crucial evidence-based strategies in the reduction of surgical site infection rates AIM: To study the impact of standardisation of transparent semipermeable dressing procedure on the rate of surgical site infection in comparison with conventional dressing in clean and clean-contaminated surgeries. METHODS: The study included 100 patients who were admitted to surgical wards in Cairo university hospitals, for clean and clean-contaminated operations, in the period from February 2017 to August 2017. Immunocompromised and uncontrolled diabetic patients were excluded. Patients were randomly allocated into two groups; in the first group, patients wounds were covered using transparent semipermeable dressing, while the second group patients’ wounds were covered using conventional occlusive gauze dressing. Patients were followed up for criteria of infection every other day during the first week then at two weeks, three weeks and four weeks. RESULTS: In clean and clean-contaminated operations, the transparent dressing group showed a significantly lesser rate of surgical site infection at (2%), compared with the conventional occlusive gauze dressing group with a surgical site infection rate of (14%) (p-value of 0.02). CONCLUSION: The transparent semipermeable dressing is effective in reducing surgical site infection rate in clean and clean-contaminated operations.

Download Full-text