scholarly journals Range of echocardiographic findings in term neonates with high oxygen requirements

1998 ◽  
Vol 78 (2) ◽  
pp. F105-F111 ◽  
Author(s):  
N. Evans ◽  
M. Kluckow ◽  
A. Currie
Keyword(s):  
High Oxygen ◽  
Term Neonates ◽  
Oxygen Requirements ◽  
Echocardiographic Findings

scholarly journals Outcomes in Patients With COVID-19 Disease and High Oxygen Requirements

2021 ◽  
Vol 13 (1) ◽  
pp. 26-37
Author(s):  
Geurys Rojas-Marte ◽  
Arsalan Talib Hashmi ◽  
Mazin Khalid ◽  
Nnamdi Chukwuka ◽  
Joshua Fogel ◽  
...  
Keyword(s):  
High Oxygen ◽  
Oxygen Requirements

Patients With High Oxygen Requirements May Respond Favorably to Different Oxygen Delivery Systems

CHEST Journal ◽  
2010 ◽  
Vol 138 (4) ◽  
pp. 574A
Author(s):  
Mary K. Hart ◽  
Erika Abmas ◽  
Mark Millard
Keyword(s):  
Oxygen Delivery ◽  
Delivery Systems ◽  
High Oxygen ◽  
Oxygen Requirements

scholarly journals Re-oxidation of cytosolic NADH is a major contributor to the high oxygen requirements of the thermotolerant yeast Ogataea parapolymorpha in oxygen-limited cultures

2021 ◽  
Author(s):  
Wijb JC Dekker ◽  
Hannes Juergens ◽  
Raúl A. Ortiz-Merino ◽  
Christiaan Mooiman ◽  
Remon van den Berg ◽  
...  
Keyword(s):  
Biomass Concentration ◽  
High Oxygen ◽  
Thermotolerant Yeast ◽  
Glycerol Production ◽  
Batch Cultures ◽  
Genes Encoding ◽  
Key Factor ◽  
Order Of Magnitude ◽  
Glycerol Formation ◽  
Oxygen Requirements

Thermotolerance is an attractive feature for yeast-based industrial ethanol production. However, incompletely understood oxygen requirements of known thermotolerant yeasts are incompatible with process requirements. To study the magnitude and molecular basis of these oxygen requirements in the facultatively fermentative, thermotolerant yeast Ogataea parapolymorpha, chemostat studies were performed under defined oxygen-sufficient and oxygen-limited cultivation regimes. The minimum oxygen requirements of O. parapolymorpha were found to be at least an order of magnitude larger than those of the thermotolerant yeast Kluyveromyces marxianus. This high oxygen requirement coincided with absence of glycerol formation, which plays a key role in NADH reoxidation in oxygen-limited cultures of other facultatively fermentative yeasts. Co-feeding of acetoin, whose reduction to 2,3-butanediol can reoxidize cytosolic NADH, supported a 2.5-fold higher biomass concentration in oxygen-limited cultures. The apparent inability of O. parapolymorpha to produce glycerol correlated with absence of orthologs of the S. cerevisiae genes encoding glycerol-3P phosphatase (ScGPP1, ScGPP2). Glycerol production was observed in aerobic batch cultures of a strain in which genes including key enzymes in mitochondrial reoxidation of NADH were deleted. However, transcriptome analysis did not identify a clear candidate for the responsible phosphatase. Expression of ScGPD2, encoding NAD+-dependent glycerol-3P dehydrogenase, and ScGPP1 in O. parapolymorpha resulted in increased glycerol production in oxygen-limited chemostats, but glycerol production rates remained substantially lower than observed in S. cerevisiae and K. marxianus. These results identify a dependency on aerobic respiration for reoxidation of NADH generated in biosynthesis as a key factor in the unexpectedly high oxygen requirements of O. parapolymorpha.

Peripheral Oxygenation In Term Neonates With In Utero Exposure To Smoking

2006 ◽  
Vol 210 (S 1) ◽  
Author(s):  
G Pichler ◽  
P Klaritsch ◽  
H Zotter ◽  
J Heinzinger ◽  
J Kutschera ◽  
...  
Keyword(s):  
In Utero ◽  
In Utero Exposure ◽  
Term Neonates

Peripheral Oxygenation In Term Neonates With In Utero Exposure To Smoking

2006 ◽  
Vol 210 (S 5) ◽  
Author(s):  
G Pichler ◽  
P Klaritsch ◽  
H Zotter ◽  
J Heinzinger ◽  
J Kutschera ◽  
...  
Keyword(s):  
In Utero ◽  
In Utero Exposure ◽  
Term Neonates

Study of Myocardial Dysfunction in Perinatal Asphyxia Field

2018 ◽  
Vol 2 (S1) ◽  
pp. e000127
Author(s):  
Kushali Tanna ◽  
K M Mehariya ◽  
Suchita Munsi ◽  
Charul Pujani
Keyword(s):  
Troponin I ◽  
Heart Diseases ◽  
Perinatal Asphyxia ◽  
Myocardial Dysfunction ◽  
Birth Asphyxia ◽  
Serum Levels ◽  
Spontaneous Respiration ◽  
Term Neonates ◽  
Myocardial Involvement ◽  
Ischemic Encephalopathy

Aims and Objectives: To study an incidence of myocardial dysfunction in neonates admitted with perinatal asphyxia, to find out its correlation with severity of birth asphyxia and its outcome. Methods: This prospective study was conducted among 40 term neonates admitted in NICU of Civil Hospital Ahmedabad who had suffered with perinatal asphyxia (defined by WHO ), resuscitated as per NRP guidelines-2015 including both intramural and extramural admissions and who developed to hypoxic ischemic encephalopathy as defined by Levene staging. Neonates with congenital heart diseases, major central nervous system malformations and neonatal sepsis were excluded. Myocardial involvement was assessed by clinical evaluation, ECG, Creatinine Kinase Total (25-200IU/L), CK-MB (0-25IU/L) and Troponin I (0-0.03ug/L) measurements. Results: Among 40 cases, 10(25%) neonates had moderate birth asphyxia while 30(75%) had severe birth asphyxia. Respiratory distress was observed in 34(77.5%), poor spontaneous respiration 4(10%),shock in 14(35%),CCF 19(47.5%) while ECG was abnormal in 30(76.7%). Serum levels of CPK Total, CPK- MB and Troponin I were raised in 34(85%), 32(80%) and 28 (70%) neonates, respectively.  Conclusion: There was a direct correlation between ECG changes and enzymatic levels which showed increasing abnormalities with increasing with severity of HIE.  

Sucrose and Facilitated Tucking for Pain Among Neonates Receiving Vaccination, in Puducherry

2017 ◽  
Vol 9 (3) ◽  
Author(s):  
Sujatha S. ◽  
Rebecca Samson ◽  
Christopher Amalraj ◽  
Sundaresan Sundaresan
Keyword(s):  
Sucrose Solution ◽  
Study Groups ◽  
Primary Outcome Measure ◽  
Intradermal Injection ◽  
Control Group ◽  
Intradermal Vaccination ◽  
Term Neonates ◽  
Bcg Vaccination ◽  
Pharmacologic Agents ◽  
Study Intervention

Neglected pain in neonates leads to various ill effects and it can be prevented by using simple and safe non-pharmacological pain relieving measures. Pharmacologic agents are not recommended in neonates for acute pain due toinvasive procedures however, administration of 24% oralsucrose solutionis found to be effective. The objective of this study was to assess the efficacy of 24%oral sucrose in combination with Facilitated tucking during BCG Vaccination through intradermalroute in term neonates which is not done elsewhere. Fifty five healthy term neonates who fulfilled the inclusion criteria such as gestational age above 37 weeks, within 24 hoursof birth age, and neonates delivered only through spontaneous vaginal delivery were included in the study. The study intervention consists of administration of 2 ml of oral 24% sucrose 2 minutes before BCG Vaccination through intradermal route and Facilitated tuckingat the time of vaccination. The primary outcome measure of cumulative NIPS score at 0, 3,5 minuteswas not significant in both the study groups. Whereas there was significant reduction in the level of pain and mean cry time in the neonates of sucrose group. Heart rateand oxygen saturation after intradermal injection also showed significant (p less than 0.001) differenceamong the neonates, who received 24% of oral sucroseand Facilitated tucking than for neonates of control group. Thus oral (24%)sucrose solution given 2 minutes before injection was effective in reducing level of neonatal pain following Intradermal Vaccination. It is a simple, safe and fast acting analgesic and should be considered for minor invasive procedures in term neonates which last for 5-7minutes.

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