scholarly journals Carbamazepine as a single drug in the treatment of epilepsy. A prospective study of serum levels and seizure control.

1978 ◽  
Vol 41 (10) ◽  
pp. 907-912 ◽  
Author(s):  
N Callaghan ◽  
M O'Callaghan ◽  
B Duggan ◽  
M Feely
Keyword(s):  
Prospective Study ◽  
Seizure Control ◽  
Serum Levels ◽  
Single Drug ◽  
Treatment Of Epilepsy ◽  
A Prospective Study

scholarly journals First, do no harm: the risks of overtreating children with epilepsy

2007 ◽  
Vol 65 (1) ◽  
pp. 1-4 ◽  
Author(s):  
Eunice Chuang ◽  
Marilisa M. Guerreiro ◽  
Sara Y. Tsuchie ◽  
Angelica Santucci ◽  
Carlos A. M. Guerreiro ◽  
...  
Keyword(s):  
Adverse Events ◽  
Prospective Study ◽  
Antiepileptic Drug ◽  
Antiepileptic Drugs ◽  
Seizure Frequency ◽  
Seizure Control ◽  
Control Method ◽  
Refractory Epilepsy ◽  
Do No Harm ◽  
A Prospective Study

BACKGROUND: Although overtreatment with antiepileptic drugs contributes to the morbidity associated with epilepsy, many children still are overtreated. OBJECTIVE: To evaluate if the withdrawal of at least one antiepileptic drug (AED) in children with refractory epilepsy using polytherapy enable a better seizure control. METHOD: This was a prospective study. Children with refractory epilepsy using at least two AEDs were included. Once the patient, or guardian, agreed to participate in the study, one or more AED were slowly tapered off. The remaining AEDs dosages could be adjusted as needed, but a new AED could not be introduced. RESULTS: Fifteen patients were evaluated, three girls; ages ranging from 3 to 18 (mean=8.7 years). After at least one AED withdrawal, two (13.5%) patients became seizure free, seizures improved >50% in 5 (33.5%) patients, did not change in 5 (33.5%), and seizure frequency became worse in 3 (20%). Adverse events improved in 12 patients (80%). CONCLUSION: The withdrawal of at least one AED is a valuable option in the treatment of selected children with refractory epilepsy.

scholarly journals Does Elevated Serum Levels of Procalcitonin Potentially Correlate with Severity of Acute Pancreatitis: A Prospective Study

2018 ◽  
Vol 08 (02) ◽  
Author(s):  
Irfan A Shera ◽  
Muzafar Rashid Shawl ◽  
Suneel Chakravarty ◽  
Vivek Raj ◽  
Ashwini K Setya
Keyword(s):  
Acute Pancreatitis ◽  
Prospective Study ◽  
Elevated Serum ◽  
Serum Levels ◽  
A Prospective Study

Ghrelin and leptin serum levels in olanzapine-induced eating behavior control disinhibition: A prospective study

2008 ◽  
Vol 98 ◽  
pp. 22
Author(s):  
K. Anselmo ◽  
E. Stip ◽  
A. Mancini-Marïe ◽  
A. Mendrek ◽  
L. Ait Bentaleb ◽  
...  
Keyword(s):  
Prospective Study ◽  
Eating Behavior ◽  
Serum Levels ◽  
Behavior Control ◽  
A Prospective Study
Sign in / Sign up

Export Citation Format

Share Document