scholarly journals Antielastin B-cell and T-cell immunity in patients with chronic obstructive pulmonary disease

Thorax ◽  
2012 ◽  
Vol 67 (8) ◽  
pp. 694-700 ◽  
Author(s):  
Manuela Rinaldi ◽  
An Lehouck ◽  
Nele Heulens ◽  
Renaud Lavend'Homme ◽  
Vincent Carlier ◽  
...  
Keyword(s):  
Chronic Obstructive Pulmonary Disease ◽  
T Cell ◽  
B Cell ◽  
Pulmonary Disease ◽  
T Cell Immunity ◽  
Chronic Obstructive ◽  
Obstructive Pulmonary Disease ◽  
Cell Immunity

scholarly journals B Cell–Adaptive Immune Profile in Emphysema-Predominant Chronic Obstructive Pulmonary Disease

2019 ◽  
Vol 200 (11) ◽  
pp. 1434-1439 ◽  
Author(s):  
John-Lawrence Sullivan ◽  
Bhavani Bagevalu ◽  
Carolyn Glass ◽  
Lynette Sholl ◽  
Monica Kraft ◽  
...  
Keyword(s):  
Chronic Obstructive Pulmonary Disease ◽  
B Cell ◽  
Pulmonary Disease ◽  
Chronic Obstructive ◽  
Obstructive Pulmonary Disease ◽  
Immune Profile ◽  
Adaptive Immune

scholarly journals Peripheral T Cell Functions Correlate with the Severity of Chronic Obstructive Pulmonary Disease

2009 ◽  
Vol 182 (5) ◽  
pp. 3270-3277 ◽  
Author(s):  
Xuehai Zhu ◽  
Aneal S. Gadgil ◽  
Rachel Givelber ◽  
M. Patricia George ◽  
Michael W. Stoner ◽  
...  
Keyword(s):  
Chronic Obstructive Pulmonary Disease ◽  
T Cell ◽  
Pulmonary Disease ◽  
Chronic Obstructive ◽  
Obstructive Pulmonary Disease ◽  
Cell Functions

Role of B Cell–Activating Factor in Chronic Obstructive Pulmonary Disease

2015 ◽  
Vol 192 (6) ◽  
pp. 706-718 ◽  
Author(s):  
Leen J. M. Seys ◽  
Fien M. Verhamme ◽  
Anja Schinwald ◽  
Hamida Hammad ◽  
Danen Mootoosamy Cunoosamy ◽  
...  
Keyword(s):  
Chronic Obstructive Pulmonary Disease ◽  
B Cell ◽  
Pulmonary Disease ◽  
Chronic Obstructive ◽  
Obstructive Pulmonary Disease ◽  
B Cell Activating Factor

CD8+T Cell Subsets and Chronic Obstructive Pulmonary Disease

1999 ◽  
Vol 160 (supplement_1) ◽  
pp. S33-S37 ◽  
Author(s):  
DAVID M. KEMENY ◽  
BEEJAL VYAS ◽  
MILICA VUKMANOVIC-STEJIC ◽  
MATTHEW J. THOMAS ◽  
ALISTAIR NOBLE ◽  
...  
Keyword(s):  
Chronic Obstructive Pulmonary Disease ◽  
T Cell ◽  
Pulmonary Disease ◽  
Cd8 T Cell ◽  
T Cell Subsets ◽  
Chronic Obstructive ◽  
Obstructive Pulmonary Disease

scholarly journals Autoimmune Mechanisms of Cardiac Remodeling in Chronic Obstructive Pulmonary Disease

2017 ◽  
Vol 44 (1) ◽  
pp. 11-16
Author(s):  
V. Dielievska ◽  
P. Kravchun
Keyword(s):  
Chronic Obstructive Pulmonary Disease ◽  
T Lymphocytes ◽  
Pulmonary Disease ◽  
Cardiac Remodeling ◽  
Heart Tissue ◽  
Autoimmune Response ◽  
Chronic Obstructive ◽  
Obstructive Pulmonary Disease ◽  
Cell Immunity ◽  
Tissue Antigens

Abstract Patients with chronic obstructive pulmonary disease (COPD) have high risk of cardiovascular events due to the remodeling of the heart and vessels. We investigated whether in COPD cardiac remodeling is associated with immune response to the inflammation by studying activated T-lymphocytes, CD3+, CD4+, CD8+ subsets of T-lymphocytes autoimmune lymphocytotoxic and granulocytotoxic antibodies, circulating immune complexes, bacterial sensibilization and hypersensitivity by the delayed type to the host heart tissue antigens. It turned out that progression of COPD is characterized by the decrease of cell immunity with formation of bacterial sensibilization and autosensibilization to the heart tissue antigens, strongly associated with cardiac remodeling. Thus, the presence of autoimmune response significantly contributes to the changes of heart geometry in patients with COPD.

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