P138 Moderate-intensity Activity is Associated with Reduced Cardiovascular Risk Factors in COPD

Abstract Background Regular physical activity (PA) has a potential antioxidant and anti-inflammatory effect that is mainly exerted on adipose tissue, skeletal muscle, and the immune and cardiovascular systems. Thus, PA is known to be beneficial in different pro-inflammatory conditions. Nevertheless, data on the role of PA in IBD patients is scarce. The aim of our study is to analyse the association of PA with clinical outcomes in IBD patients. Methods Cross-sectional prospective study including all consecutive IBD patients attended at a university hospital was performed. Data on physical activity was recorded through the International Physical Activity Questionnaire (IPAQ). Metabolic Equivalent Task (MET) hours per week were calculated according to the combination of walking, moderate-intensity or vigorous intensity activity, and patients were categorized into low, moderate or high PA according to a previously validated method. Data on IBD phenotype, activity indexes, natural history, current and past treatments, together with liver evaluation, and history of cardiovascular risk factors were also collected. Results 831 patients were included in the study. Study flow chart is depicted in figure and clinical characteristics in table 1. IBD patients with a low or moderate PA showed a tendency to a higher proportion of IBD-related complications and higher scores in disease activity indexes than those with high PA. PA was strongly associated to the metabolic profile. Patients with a low/moderate PA were more frequently obese, hypertense, diabetic and had dyslipidaemia. Regarding liver disease, PA was significantly associated to the presence of non-alcoholic fatty liver disease (NAFLD), but not with advanced liver fibrosis. Conclusion Insufficient PA can negatively impact clinical outcomes in IBD patients, probably not because of a direct effect on IBD-pathogenesis, but due to its strong association with cardiovascular risk factors and NAFLD.

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Moderate-intensity physical activity and cardiovascular risk factors: The Stanford five-city project

Preventive Medicine ◽

10.1016/0091-7435(86)90061-7 ◽

1986 ◽

Vol 15 (6) ◽

pp. 561-568 ◽

Cited By ~ 32

Author(s):

James F. Sallis ◽

William L. Haskell ◽

Stephen P. Fortmann ◽

Peter D. Wood ◽

Karen M. Vranizan

Keyword(s):

Physical Activity ◽

Risk Factors ◽

Cardiovascular Risk ◽

Cardiovascular Risk Factors ◽

Moderate Intensity ◽

Moderate Intensity Physical Activity ◽

Intensity Physical Activity

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Is the Clinical Delivery of Cardiac Rehabilitation in an Australian Setting Associated with Changes in Physical Capacity and Cardiovascular Risk and Are Any Changes Maintained for 12 Months?

International Journal of Environmental Research and Public Health ◽

10.3390/ijerph18178950 ◽

2021 ◽

Vol 18 (17) ◽

pp. 8950

Author(s):

Kym Joanne Price ◽

Brett Ashley Gordon ◽

Stephen Richard Bird ◽

Amanda Clare Benson

Keyword(s):

Risk Factors ◽

Cardiovascular Risk ◽

Waist Circumference ◽

Cardiac Rehabilitation ◽

Cardiovascular Risk Factors ◽

Cardiorespiratory Fitness ◽

Rehabilitation Program ◽

Physical Capacity ◽

Moderate Intensity ◽

Cardiac Rehabilitation Program

Long-term maintenance of changes in cardiovascular risk factors and physical capacity once patients leave the supervised program environment have not previously been reported. This study investigated the changes in physical capacity outcomes and cardiovascular risk factors in an Australian cardiac rehabilitation setting, and the maintenance of changes in these outcomes in the 12 months following cardiac rehabilitation attendance. Improvements in mean (95% CI) cardiorespiratory fitness (16.4% (13.2–19.6%), p < 0.001) and handgrip strength (8.0% (5.4–10.6%), p < 0.001) were observed over the course of the cardiac rehabilitation program, and these improvements were maintained in the 12 months following completion. Waist circumference (p = 0.003) and high-density lipoprotein cholesterol (p < 0.001) were the only traditional cardiovascular risk factors to improve during the cardiac rehabilitation program. Vigorous-intensity aerobic exercise was associated with significantly greater improvements in cardiorespiratory fitness, Framingham risk score, and waist circumference in comparison to moderate-intensity exercise. An increase in the intensity of the exercise prescribed during cardiac rehabilitation in Australia is recommended to induce larger improvements in physical capacity outcomes and cardiovascular risk. A standardized exercise test at the beginning of the rehabilitation program is recommended to facilitate appropriate prescription of exercise intensity.

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