scholarly journals Comparison of pain response after subcutaneous injection of two maropitant formulations to beagle dogs

2018 ◽  
Vol 5 (1) ◽  
pp. e000262 ◽  
Author(s):  
Nynke Deckers ◽  
Catharina A Ruigrok ◽  
Hans Peter Verhoeve ◽  
Nicky Lourens
Keyword(s):  
Visual Analogue Scale ◽  
Benzyl Alcohol ◽  
Subcutaneous Injection ◽  
Analogue Scale ◽  
Injection Pain ◽  
Pain Response ◽  
Beagle Dogs ◽  
Subcutaneous Injections ◽  
Local Pain ◽  
Descriptive Scale

The antiemetic maropitant, with metacresol as preservative (Cerenia, Zoetis), has been associated with pain after subcutaneous injection in dogs and cats. Recently, a generic formulation containing benzyl alcohol was authorised (Prevomax, Le Vet). Benzyl alcohol is reported to have local anaesthetic properties and reduce injection pain. This study compared local pain after subcutaneous injection of the two maropitant formulations, administered at approximately 4°C and 25°C, to dogs. Thirty-two healthy beagle dogs were enrolled into a blinded, randomised, cross-over study. Dogs received subcutaneous injections of maropitant injection containing metacresol as preservative and maropitant injection containing benzyl alcohol as preservative, both at approximately 4°C and 25°C, with at least three days in between treatments. Injection pain was evaluated by two blinded observers using a visual analogue scale immediately after injection and a simple descriptive scale at two minutes after injection. In healthy beagle dogs, subcutaneous injection of maropitant with benzyl alcohol is significantly less painful than injection of maropitant with metacresol.

Prospective comparison of perioperative wound and pain score parameters in cats undergoing flank vs midline ovariectomy

2019 ◽  
Vol 22 (2) ◽  
pp. 168-177 ◽  
Author(s):  
Matthew J Swaffield ◽  
Sara L Molloy ◽  
Victoria J Lipscomb
Keyword(s):  
Visual Analogue Scale ◽  
Pain Score ◽  
Analogue Scale ◽  
Intraoperative Complications ◽  
Pain Scale ◽  
Surgical Wound ◽  
Wound Breakdown ◽  
Prospective Comparison ◽  
Duration Of Surgery ◽  
Descriptive Scale

Objectives The aim of this study was to prospectively compare perioperative pain score and wound parameters, inclusive of postoperative swelling and erythema, between flank and midline ovariectomy (OVE) in cats, performed by final-year veterinary students. Methods Healthy cats presented for routine OVE were randomly assigned to either the midline or flank group after owner consent to participate in the study. Perioperative protocols were standardised for both groups. Clinical data were collected prior to surgery, intraoperatively, at 1 h postoperatively, at the time of discharge, and at 3 and 10 day postoperative re-examination appointments. Data recorded included duration of surgery and anaesthesia, intraoperative complications, Feline Acute Pain Scale (FAPS) scores, a simple descriptive scale of reaction to wound palpation (SDSwound), a dynamic and interactive visual analogue scale assessment of pain (DIVAS), and both a simple descriptive scale (SDSswelling) and a visual analogue scale (VASswelling) of surgical wound swelling. Results Thirty-eight cats received a flank OVE and 37 received a midline OVE. Duration of surgery, duration of anaesthesia and intraoperative complications did not vary significantly between the two groups. Cats in both groups had significantly higher FAPS scores after surgery ( P = 0.0002), with cats receiving a flank OVE having significantly higher pain scores compared with a midline OVE at 1 h postoperatively ( P = 0.0004) and at discharge ( P = 0.002). Swelling of the surgical wound (SDSswelling) was significantly higher in cats receiving a midline OVE at the time of discharge ( P = 0.048), as well as at the 3 day ( P <0.0001) and 10 day ( P = 0.001) postoperative re-examinations. FAPS scores were significantly higher in cats receiving a midline OVE at the 3 day ( P = 0.016) and 10 day re-examinations ( P = 0.045). No cats in either group suffered a wound breakdown or infection. Conclusions and relevance Our study does not support advocating a preferred surgical approach for feline OVE within a teaching environment.

Safety of Subcutaneous Microinjections (Mesotherapy) in Musicians

2011 ◽  
Vol 26 (2) ◽  
pp. 79-83 ◽  
Author(s):  
Danik A Narvarte ◽  
Jaume Rosset-Llobet
Keyword(s):  
Side Effects ◽  
Visual Analogue Scale ◽  
Analogue Scale ◽  
Systemic Infection ◽  
Muscular Weakness ◽  
Musculoskeletal Complaints ◽  
Subcutaneous Injections ◽  
Levator Scapulae ◽  
The Mean ◽  
Systemic Symptoms

OBJECTIVE: Determine the safety and tolerance of mesotherapy as a technique for the treatment of musculoskeletal complaints in musicians. METHOD: 67 patients (55.2% women) were subjected to a total of 267 mesotherapy sessions. A mesotherapy needle or normal needle was used randomly. The drugs employed were thiocolchicoside and diazepam as muscular relaxants, pentoxifylline or buflomedil as vasodilators, and piroxicam as an anti-inflammatory, as directed. A visual analogue scale was used to quantify the pain produced by the microinjections as well as the degree of immediate and midterm side effects as reported on a standard questionnaire. RESULTS: A mean of 155.5 microinjections were performed per session, of which 45.6% were perceived as painful by the patient with a mean severity of 4.3 out of 10. The pain reduced to 0.5 out of 10 after 24 hours. The most sensitive areas were the levator scapulae and splenius muscles. Systemic symptoms were reported by 5.99% of the musicians after the mesotherapy sessions (muscular weakness 1.5%, rash 1.5%, drowsiness 1.1% and itching 1.1%, being the most frequent). The mean severity of these symptoms was 2.77 out of 10. In all cases the symptoms had completely disappeared after 24 hours. No patient referred to signs of local or systemic infection. CONCLUSIONS: The application of drugs by means of subcutaneous injections (mesotherapy) in musicians is a technique that is safe, well tolerated, and without any severe complications.

scholarly journals Effects of Smoke Exposure and Other Lifestyle Factors on Pain Response to Electrical Stimulation in Women

2008 ◽  
Vol 13 (3) ◽  
pp. 231-235 ◽  
Author(s):  
Joy Yenn May Wee ◽  
Wilma M Hopman
Keyword(s):  
Electrical Stimulation ◽  
Alcohol Use ◽  
Visual Analogue Scale ◽  
Analogue Scale ◽  
Smoke Exposure ◽  
Second Hand Smoke ◽  
Population Exposure ◽  
Pain Response ◽  
Pain Ratings ◽  
Lower Pain

BACKGROUND: A relationship between smoking and development of pain syndromes has been suggested in the literature. The present study examined associations between smoke exposure and other related variables, and pain response to suprathreshold electrical stimulation.METHODS: Subjects were prospectively recruited from a population referred to an electrodiagnostic clinic. Information about age, smoke exposure, caffeine and alcohol consumption was obtained, as well as documented objective signs of stress through physical assessment. One investigator applied two standardized 0.1 ms electrical stimulations (50 mA followed by 100 mA) to asymptomatic extremities at the beginning of each electrodiagnostic session, using consistent technique. Subjects used a visual analogue scale to indicate the level of pain felt after each stimulation.RESULTS: Two hundred fifteen women were included. Current smokers and those currently exposed to second-hand smoke had significantly higher pain ratings (P=0.003 for 50 mA, P=0.005 for 100 mA) than those not currently exposed to smoke. Time since exposure was negatively associated with pain ratings. Those with objective signs of stress reported higher levels of pain, which was significant for the 100 mA stimulation (P=0.046). Linear regression modelling indicated that current smoke exposure and alcohol use were associated with higher pain ratings at both 50 mA and 100 mA, while stress was associated with higher pain ratings and older age was associated with lower pain ratings at 100 mA only.INTERPRETATION: Exposure to cigarette smoke is significantly related to higher reported levels of pain experienced in response to electrical stimulation in this study population. Exposure to smoke can add 10 points to the 100-point visual analogue scale compared with subjects without exposure, with alcohol use adding another eight points. Reported pain decreases as length of time since previous exposure to smoke increases.

Carpal Ligament Decompression Under Local Anaesthesia: the Effect of lidocaine warming and Alkalinisation on Infiltration Pain

2004 ◽  
Vol 29 (1) ◽  
pp. 32-34 ◽  
Author(s):  
C. K. YIANNAKOPOULOS
Keyword(s):  
Visual Analogue Scale ◽  
Carpal Tunnel ◽  
Analogue Scale ◽  
Needle Insertion ◽  
Injection Pain ◽  
Significant Difference ◽  
Skin Infiltration ◽  
Group A ◽  
Vas Scores ◽  
Group B

This study investigated the effects of alkalinization and warming of lidocaine 1% on injection pain in patients undergoing carpal tunnel decompression. Sixty-four adult patients were randomly allocated into one of three groups: Group A ( n=20) received plain lidocaine 1%, Group B ( n = 22) alkalinized lidocaine and Group C ( n = 22) warmed and alkalinized lidocaine. Pain on needle insertion and on infiltration was assessed using a 100 mm Visual Analogue Scale (VAS). There was no significant difference regarding pain on needle insertion whereas significant differences were noted in reference to infiltration pain. In Groups B and C (alkalinized lidocaine) the VAS scores on skin infiltration were significantly lower than in Group A, while the pain score in Group C (alkalinized and warmed lidocaine) was significantly lower than in Group B.

scholarly journals Evaluation of Efficacy of Customized Lidocaine Bioadhesive Anaesthetic Patch for Extraction of Primary Tooth - An Invitro Study

2021 ◽  
Vol 10 (24) ◽  
pp. 1830-1834
Author(s):  
Amith Adyanthaya ◽  
Risana K ◽  
Aparna Sivaraman ◽  
Gopika Gopan A ◽  
Nazreen Ayub K. ◽  
...  
Keyword(s):  
Visual Analogue Scale ◽  
Analogue Scale ◽  
Anaesthetic Agent ◽  
Age Groups ◽  
Negative Influence ◽  
Paediatric Dentistry ◽  
Primary Tooth ◽  
P Value ◽  
Pain Response ◽  
Chi Square

BACKGROUND We wanted to clinically evaluate the efficacy of lidocaine bioadhesive patches for extraction in paediatric dentistry and assess the comfort and pain response by sound eye motor (SEM) scale and intensity of pain using the visual analogue scale (VAS). METHODS A total of thirty-five co-operative children of age group 8 - 12 years without systemic diseases who needed dental extraction participated in the study. Extraction was carried out using customized lidocaine bioadhesive patches as anaesthetic agent. Evaluation of comfort and pain response was done by sound eye motor scale and intensity of pain using the visual analogue scale. Statistical analysis was done with SPSS version 2.0. Comparison of SEM scale and VAS scores between different subgroups was done using a chi-square test. P value less than 0.001 was considered statistically significant. RESULTS Children of higher age groups belonging to both the genders demonstrated less perception to pain during extractions using lidocaine patch. During extraction of firm teeth and teeth with Grade I mobility, perception of pain was more in girls. Maxillary arch extraction in children with various grades of mobility perceived less pain. Irrespective of age, gender and arches,teeth with Grade II and Grade III mobility were extracted with minimal VAS and SEM score. CONCLUSIONS Bioadhesive patches serve as a potential non-invasive alternative to traditional modes of local anaesthetic delivery with the advantage of eliminating needle phobia and possible negative influence on the behaviour. KEY WORDS Bioadhesive Patches, Lidocaine, Extraction, Paediatric Dentistry

Intoxication Perception Visual Analogue Scale

2010 ◽  
Author(s):  
Jennifer R. Cromer ◽  
Jason A. Cromer ◽  
Paul Maruff ◽  
Peter J. Snyder
Keyword(s):  
Visual Analogue Scale ◽  
Analogue Scale

EFEKTIFITAS PENGGUNAAN TERAPI TRANSCUTANEUS ELECTRICAL NERVE STIMULATION (TENS) PADA PASIEN NYERI PUNGGUNG BAWAH DI RSUD dr. M HAULUSSY AMBON

2018 ◽  
pp. 70-78
Author(s):  
Ninik Maathia Sallatalohy ◽  
Mauren J Paliyama ◽  
Farah Ch Noya
Keyword(s):  
Visual Analogue Scale ◽  
Nerve Stimulation ◽  
Analogue Scale ◽  
Electrical Nerve Stimulation

Pendahuluan. Nyeri Punggung Bawah (NPB) merupakan suatu permasalahan yang paling sering ditemukan di masyarakat. Etiologinya tergolong kompleks dan dapat disebabkan oleh berbagai hal. Salah satu pilihan penatalaksanaan NPB adalah dengan terapi TENS. Tujuan. Tujuan penelitian ini adalah untuk mengetahui efektifitas terapi TENS pada pasien NPB di RSUD dr. M Haulussy Ambon. Metode. Desain penelitian yang digunakan adalah pretest–posttest design, dengan mengukur skala Visual Analogue Scale (VAS) sebelum dan setelah 5 kali terapi TENS. Jumlah subjek yang memenuhi kriteria sebanyak 71 dengan perbandingan laki-laki dan perempuan adalah 1:2. Hasil. Hasil uji Marginal Homogenity memperlihatkan perbedaan signifikansi sebelum dan setelah 5 kali terapi TENS (p = 0,000). Kesimpulan. TENS efektif dalam meredakan nyeri pada pasien NPB. Kata Kunci: Nyeri Punggung Bawah, TENS

A Novel Virtual Reality Technique (Cervigame®) Compared to Conventional Proprioceptive Training to Treat Neck Pain: A Randomized Controlled Trial

2019 ◽  
Vol 9 (3Jun) ◽  
Author(s):  
I Rezaei ◽  
M Razeghi ◽  
S Ebrahimi ◽  
S Kayedi ◽  
A Rezaeian Zadeh
Keyword(s):  
Virtual Reality ◽  
Visual Analogue Scale ◽  
Neck Pain ◽  
Analogue Scale ◽  
Controlled Trial ◽  
Neck Disability Index ◽  
Repeated Measure ◽  
Balance Test ◽  
Proprioceptive Training ◽  
Neck Disability

Background: Despite the potential benefits of virtual reality technology in physical rehabilitation, only a few studies have evaluated the efficacy of this type of treatment in patients with neck pain.Objective: The aim of this study was to compare the effects of virtual reality training (VRT) versus conventional proprioceptive training (CPT) in patients with neck pain.Methods: Forty four participants with nonspecific chronic neck pain were randomly assigned to VRT or CPT in this assessor-blinded clinical trial. A novel videogame called Cervigame® was designed for VRT. It comprises of 50 stages divided into unidirectional and two-directional stages ordered from easy to hard. CPT consisted of eye-follow, gaze stability, eye-head coordination and position and movement sense training. Both groups completed 8 training sessions over 4 weeks. Visual analogue scale score, neck disability index and Y-balance test results were recorded at baseline, immediately after and 5 weeks post-intervention. Mixed repeated measure ANOVA was used to analyze differences between mean values for each variable at an alpha level of 0.05.Results: There were significant improvements in all variables in both groups immediately after and 5 weeks after the intervention. Greater improvements were observed in the visual analogue scale and neck disability index scores in VRT group, and the results for all directions in Y-balance test were similar in both groups. No side effects were reported.Conclusion: Improvements in neck pain and disability were greater in VRT than CPT group. Cervigame® is a potentially practical tool for rehabilitation in patients with neck pain.

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