scholarly journals Monitoring Mycobacterium bovis in Eurasian badgers (Meles meles) killed by vehicles in Northern Ireland between 1998 and 2011

2017 ◽  
Vol 182 (9) ◽  
pp. 259-259 ◽  
Author(s):  
Emily A Courcier ◽  
Fraser D Menzies ◽  
Sam A J Strain ◽  
Robin A Skuce ◽  
Philip A Robinson ◽  
...  
Keyword(s):  
Northern Ireland ◽  
Mycobacterium Bovis ◽  
Meles Meles

Behaviour of badgers (Meles meles) in farm buildings: Opportunities for the transmission of Mycobacterium bovis to cattle?

2009 ◽  
Vol 117 (1-2) ◽  
pp. 103-113 ◽  
Author(s):  
Bryony A. Tolhurst ◽  
Richard J. Delahay ◽  
Neil J. Walker ◽  
Alastair I. Ward ◽  
Timothy J. Roper
Keyword(s):  
Mycobacterium Bovis ◽  
Meles Meles ◽  
Farm Buildings

Long-term temporal trends and estimated transmission rates for Mycobacterium bovis infection in an undisturbed high-density badger (Meles meles) population

2013 ◽  
Vol 141 (7) ◽  
pp. 1445-1456 ◽  
Author(s):  
R. J. DELAHAY ◽  
N. WALKER ◽  
G. S. SMITH ◽  
D. WILKINSON ◽  
R. S. CLIFTON-HADLEY ◽  
...  
Keyword(s):  
Mycobacterium Bovis ◽  
Serological Test ◽  
Temporal Trends ◽  
Positive Culture ◽  
Host Density ◽  
Meles Meles ◽  
Simple Relationship ◽  
Transmission Rates ◽  
Epidemiological Trends

SUMMARYWe describe epidemiological trends in Mycobacterium bovis infection in an undisturbed wild badger (Meles meles) population. Data were derived from the capture, clinical sampling and serological testing of 1803 badgers over 9945 capture events spanning 24 years. Incidence and prevalence increased over time, exhibiting no simple relationship with host density. Potential explanations are presented for a marked increase in the frequency of positive serological test results. Transmission rates (R0) estimated from empirical data were consistent with modelled estimates and robust to changes in test sensitivity and the spatial extent of the population at risk. The risk of a positive culture or serological test result increased with badger age, and varied seasonally. Evidence consistent with progressive disease was found in cubs. This study demonstrates the value of long-term data and the repeated application of imperfect diagnostic tests as indices of infection to reveal epidemiological trends in M. bovis infection in badgers.

scholarly journals Long-term temporal trends and estimated transmission rates for Mycobacterium bovis infection in an undisturbed high-density badger (Meles meles) population – CORRIGENDUM

2013 ◽  
Vol 141 (7) ◽  
pp. 1457-1457 ◽  
Author(s):  
R. J. DELAHAY ◽  
N. WALKER ◽  
G. S. SMITH ◽  
D. WILKINSON ◽  
R. S. CLIFTON-HADLEY ◽  
...  
Keyword(s):  
Mycobacterium Bovis ◽  
Temporal Trends ◽  
Meles Meles ◽  
High Density ◽  
Transmission Rates

scholarly journals The occurrence of Mycobacterium bovis infection in cattle in and around an area subject to extensive badger (Meles meles) control

1995 ◽  
Vol 114 (1) ◽  
pp. 179-193 ◽  
Author(s):  
R. S. Clifton-Hadley ◽  
J. W. Wilesmith ◽  
M. S. Richards ◽  
P. Upton ◽  
S. Johnston
Keyword(s):  
Mycobacterium Bovis ◽  
Proportional Hazards ◽  
Meles Meles ◽  
The Other ◽  
Small Scale ◽  
Total Clearance ◽  
Proportional Hazards Regression ◽  
South West ◽  
Cattle Herds ◽  
South West England

SUMMARYThe occurrence of Mycobacterium bovis infection in cattle herds during the period 1966–92 in two geographically related areas in South-West England is compared. In one area comprising 104 km2 all badgers were systematically destroyed from 1975–81, after which recolonization was allowed; in the other, comprising 116 km2, small scale, statutory badger removal operations were undertaken from 1975 onwards where specific herds were detected with M. bovis infection. In the area with total clearance, no further incidents with M. bovis isolation occurred from 1982–92. Survival analysis and proportional hazards regression indicated that the risk of herds being identified with infection was less once badgers had been cleared from their neighbourhood, whereas it was greater in herds with 50 or more animals, and once cattle in a herd had responded positively to the tuberculin skin test, even though infection with M. bovis was not confirmed subsequently. The study provides further evidence that badgers represent an important reservoir of M. bovis infection for cattle and that badger control is effective in reducing incidents of cattle infection with M. bovis if action is thorough and recolonization is prevented.

Heterogeneity in the risk of Mycobacterium bovis infection in European badger (Meles meles) cubs

2013 ◽  
Vol 141 (7) ◽  
pp. 1458-1466 ◽  
Author(s):  
A. J. TOMLINSON ◽  
M. A. CHAMBERS ◽  
S. P. CARTER ◽  
G. J. WILSON ◽  
G. C. SMITH ◽  
...  
Keyword(s):  
Mycobacterium Bovis ◽  
Bovine Tuberculosis ◽  
Control Strategies ◽  
Temporal Distribution ◽  
Population Level ◽  
Meles Meles ◽  
Structured Populations ◽  
Risk Of Infection ◽  
Spatio Temporal ◽  
European Badgers

SUMMARYThe behaviour of certain infected individuals within socially structured populations can have a disproportionately large effect on the spatio-temporal distribution of infection. Endemic infection with Mycobacterium bovis in European badgers (Meles meles) in Great Britain and Ireland is an important source of bovine tuberculosis in cattle. Here we quantify the risk of infection in badger cubs in a high-density wild badger population, in relation to the infection status of resident adults. Over a 24-year period, we observed variation in the risk of cub infection, with those born into groups with resident infectious breeding females being over four times as likely to be detected excreting M. bovis than cubs from groups where there was no evidence of infection in adults. We discuss how our findings relate to the persistence of infection at both social group and population level, and the potential implications for disease control strategies.

Experimental tuberculosis in the European badger (Meles meles) after endobronchial inoculation of Mycobacterium bovis: I. Pathology and bacteriology

2007 ◽  
Vol 83 (1) ◽  
pp. 53-62 ◽  
Author(s):  
L.A.L. Corner ◽  
E. Costello ◽  
S. Lesellier ◽  
D. O’Meara ◽  
D.P. Sleeman ◽  
...  
Keyword(s):  
Mycobacterium Bovis ◽  
Meles Meles ◽  
Experimental Tuberculosis ◽  
European Badger

scholarly journals Protective Effect of Oral BCG and Inactivated Mycobacterium bovis Vaccines in European Badgers (Meles meles) Experimentally Infected With M. bovis

2020 ◽  
Vol 7 ◽  
Author(s):  
Ana Balseiro ◽  
José Miguel Prieto ◽  
Vega Álvarez ◽  
Sandrine Lesellier ◽  
Dipesh Davé ◽  
...  
Keyword(s):  
Protective Effect ◽  
Mycobacterium Bovis ◽  
Meles Meles ◽  
European Badgers

scholarly journals Quantitative interferon-gamma responses predict future disease progression in badgers naturally infected with Mycobacterium bovis

2017 ◽  
Vol 145 (15) ◽  
pp. 3204-3213 ◽  
Author(s):  
S. N. BUZDUGAN ◽  
M. A. CHAMBERS ◽  
R. J. DELAHAY ◽  
J. A. DREWE
Keyword(s):  
Immune Response ◽  
Disease Progression ◽  
Diagnostic Test ◽  
Mycobacterium Bovis ◽  
Serological Test ◽  
Clinical Sample ◽  
Management Strategies ◽  
Meles Meles ◽  
Cattle Industry ◽  
Mycobacterial Culture

SUMMARYThe diagnosis and control of Mycobacterium bovis infection (bovine tuberculosis: TB) continues to present huge challenges to the British cattle industry. A clearer understanding of the magnitude and duration of immune response to M. bovis infection in the European badger (Meles meles) – a wildlife maintenance host – may assist with the future development of diagnostic tests, and vaccination and disease management strategies. Here, we analyse 5280 diagnostic test results from 550 live wild badgers from a naturally-infected population to investigate whether one diagnostic test (a gamma interferon release [IFNγ] assay, n = 550 tests) could be used to predict future positive results on two other tests for the same disease (a serological test [n = 2342 tests] and mycobacterial culture [n = 2388 tests]) and hence act as an indicator of likely bacterial excretion or disease progression. Badgers with the highest IFNγ optical density (OD) values were most likely to subsequently test positive on both serological and culture tests, and this effect was detectable for up to 24 months after the IFNγ test. Furthermore, the higher the original IFNγ OD value, the greater the chance that a badger would subsequently test positive using serology. Relationships between IFNγ titres and mycobacterial culture results from different types of clinical sample suggest that the route of infection may affect the magnitude of immune response in badgers. These findings identify further value in the IFNγ test as a useful research tool, as it may help us to target studies at animals and groups that are most likely to succumb to more progressive disease.

Vaccination of the badger (Meles meles) against Mycobacterium bovis

1996 ◽  
Vol 51 (3-4) ◽  
pp. 363-379 ◽  
Author(s):  
M.S. Hughes ◽  
S.D. Neill ◽  
M.S. Rogers
Keyword(s):  
Mycobacterium Bovis ◽  
Meles Meles
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