A carboxyfunctionalized (24)-1,6-pyrenophane-tetraene by glyoxylic Perkin condensation

2017 ◽  
Vol 95 (4) ◽  
pp. 450-453 ◽  
Author(s):  
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Pierre Dechambenoit ◽  
Harald Bock ◽  
Fabien Durola

Without employing high dilution conditions, the fourfold 2+2 Perkin reaction of 1,6-pyrenylene-diglyoxylic acid with its reduction product 1,6-pyrenylene-diacetic acid yields the corresponding tetrameric conjugated macrocycle in 25% overall yield after in-situ esterification. The macrocycle adopts a square fourfold symmetry in the crystal, with near-vertical pyrene walls that alternatingly tilt upwards and downwards.

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BioResources ◽  
2015 ◽  
Vol 10 (3) ◽  
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