Evidence for the presence of rat a α1-acid glycoprotein in granuloma tissue: a fluorescence microscopy study

1980 ◽  
Vol 58 (9) ◽  
pp. 1513-1517 ◽  
Author(s):  
J. C. Jamieson ◽  
B. Turchen ◽  
E. Huebner
Keyword(s):  
Connective Tissue ◽  
Fluorescence Microscopy ◽  
Inflammatory Process ◽  
Microscopy Study ◽  
Acid Glycoprotein ◽  
Inflammatory Site ◽  
Tissue Region ◽  
Granuloma Tissue

Turpentine granulomas were produced in rats and examined histologically and for the presence of rat albumin and α1-acid glycoprotein using fluorescent labelled antibody to these proteins. Examination of granulomas showed the presence of a connective tissue region of granuloma tissue; this region stained strongly with fluorescent anti-α1-acid glycoprotein whereas there was little staining with fluorescent antialbumin. These results suggest that α1-acid glycoprotein is located at the inflammatory site and may be involved in some aspect of the inflammatory process.

scholarly journals Method for the prevention of inflammatory processes in the bone part of the external auditory canal accompanied by the growth of connective tissue

2020 ◽  
Vol 19 (4) ◽  
pp. 21-26
Author(s):  
I. A. Anikin ◽  
◽  
S. A. Eremin ◽  
A. E. Shinkareva ◽  
◽  
...  
Keyword(s):  
Hearing Loss ◽  
Connective Tissue ◽  
Granulation Tissue ◽  
Satisfactory Result ◽  
External Auditory Canal ◽  
Inflammatory Process ◽  
Local Therapy ◽  
Scar Tissue ◽  
Inflammatory Processes ◽  
Bone Section

Otosurgery plays an important role in the rehabilitation of patients with hearing loss. Any operation can be accompanied by a long inflammatory process with excessive development of connective tissue, forming atresia or stenosis of the external auditory canal. Formed scars in the external auditory canal reduce the effectiveness of treatment and can lead to reoperation. In the treatment of scars, the use of injections of a suspension of prolonged steroids directly into the developing connective tissue is effective. We have developed a method of injecting drugs into the scar tissue of the bone section of the external auditory canal, which allows the use of such therapy in patients after otosurgery. 12 people were treated with the proposed technique. All patients had an inflammatory process in the external auditory canal with undesirable growth of connective tissue. Previous local therapy did not bring a satisfactory result. Patients received injections of a suspension of steroids into developing scar tissue. The treatment period was 1-8 weeks, for which 1 to 4 sessions of injections were performed. As a result of treatment according to the developed method, in all cases a cessation of the pathological inflammatory process was observed. Timely therapy made it possible to completely eliminate the excess granulation tissue (100%), to stop the growth of the scar, or even to cause a significant decrease (33%). The developed method allows to use of a small dose of a substance (0,1–0,5 ml) for injection to achieve the desired therapeutic effect.

scholarly journals HDL particles incorporate into lipid bilayers – a combined AFM and single molecule fluorescence microscopy study

2017 ◽  
Vol 7 (1) ◽  
Author(s):  
Birgit Plochberger ◽  
Clemens Röhrl ◽  
Johannes Preiner ◽  
Christian Rankl ◽  
Mario Brameshuber ◽  
...  
Keyword(s):  
Fluorescence Microscopy ◽  
Lipid Bilayers ◽  
Single Molecule ◽  
Microscopy Study ◽  
Single Molecule Fluorescence ◽  
Single Molecule Fluorescence Microscopy

Fluorescence Microscopy Study of the Sorption of Cationic Polymers on Hair

1999 ◽  
pp. 276-286
Author(s):  
S. T. A. Regismond ◽  
Y.-M. Heng ◽  
E. D. Goddard ◽  
F. M. Winnik
Keyword(s):  
Fluorescence Microscopy ◽  
Microscopy Study ◽  
Cationic Polymers
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