Hematologic, biochemical, and endocrine characteristics of bobcats during a prey decline in southeastern Idaho

1993 ◽  
Vol 71 (7) ◽  
pp. 1448-1453 ◽  
Author(s):  
Steven T. Knick ◽  
Eric C. Hellgren ◽  
Ulysses S. Seal
Keyword(s):  
Cell Volume ◽  
Packed Cell Volume ◽  
Mean Corpuscular Volume ◽  
Blood Chemistry ◽  
Mean Corpuscular Hemoglobin ◽  
Corpuscular Volume ◽  
Corpuscular Hemoglobin ◽  
Felis Rufus ◽  
Cholesterol Levels ◽  
Lepus Californicus

We studied the hematology and blood chemistry of 33 adult bobcats (Felis rufus) captured from 1982 through 1985 in southeastern Idaho during a decline in lagomorphs, their major prey. Our objectives were to relate blood physiology of bobcats to sex, season, and a decline in abundance of black-tailed jackrabbits (Lepus californicus) and Nuttall's cottontail rabbits (Sylvilagus nuttallii). Males had higher (P < 0.10) erythrocyte counts (RBC) and hemoglobin levels (Hb) and lower (P < 0.10) insulin concentrations than females. Bobcats sampled during spring had higher (P < 0.10) mean corpuscular volume (MCV), mean corpuscular hemoglobin (MCH) and'insulin levels, and lower (P < 0.10) Hb, packed cell volume (PCV), RBC, and cholesterol levels than bobcats captured in autumn. The decline in lagomorph prey abundance from 1982 to 1983 was reflected in bobcat blood by lower (P < 0.10) phosphorus and insulin levels and higher (P < 0.10) Hb, RBC, and PCV. Progesterone levels in females reflected field results indicating that reproduction was curtailed when prey was scarce.

scholarly journals Inaccuracy in automated measurement of hematocrit and corpuscular indices in the presence of severe hyperglycemia

Blood ◽  
1981 ◽  
Vol 57 (6) ◽  
pp. 1065-1067 ◽  
Author(s):  
JA Strauchen ◽  
W Alston ◽  
J Anderson ◽  
Z Gustafson ◽  
LF Fajardo
Keyword(s):  
Blood Glucose ◽  
Mean Corpuscular Volume ◽  
Hemoglobin Concentration ◽  
Mean Corpuscular Hemoglobin ◽  
Corpuscular Volume ◽  
Automated Measurement ◽  
Mean Corpuscular Hemoglobin Concentration ◽  
Corpuscular Hemoglobin ◽  
Hyperosmolar Glucose

Abstract Because we recently observed two patients with severe diabetic hyperglycemia and spuriously elevated electronically determined hematocrit and mean corpuscular volume (MCV), we investigated the effect of hyperglycemia on two popular automated hematology systems, the Coulter S and Ortho ELT-8. Marked hyperglycemia (blood glucose 800-- 2000 mg/dl) caused consistent overestimation of the electronically determined MCV compared to that derived from a simultaneous spun microhematocrit. The resultant overestimation and underestimation, respectively, of the derived values for hematocrit and mean corpuscular hemoglobin concentration may be clinically misleading. The mechanism of MCV elevation in hyperglycemia appears to be swelling of hyperosmolar glucose “loaded” erythrocytes when diluted into “isotonic” counting medium. This effect is readily circumvented by determination of a spun microhematocrit.

Nilai Mean Corpuscular Hemoglobin Concentration, Mean Corpuscular Volume dan Mean Corpuscular Hemoglobin Darah Sapi Bali yang Dipelihara Berbasis Organik

2021 ◽  
pp. 39
Author(s):  
I Gede Agus Eva Prawira Adinata ◽  
Ni Ketut Suwiti ◽  
Anak Agung Sagung Kendran
Keyword(s):  
Mean Corpuscular Volume ◽  
Hemoglobin Concentration ◽  
Mean Corpuscular Hemoglobin ◽  
Corpuscular Volume ◽  
Mean Corpuscular Hemoglobin Concentration ◽  
Corpuscular Hemoglobin ◽  
Corpuscular Haemoglobin ◽  
Corpuscular Hemoglobin Concentration ◽  
Hematology Analyzer ◽  
Mean Corpuscular Haemoglobin

Telah dilakukan penelitian untuk mengetahui nilai hematologi MCHC (Mean Corpuscular Hemoglobin Concentration), MCV (Mean Corpuscular Volume) dan MCH (Mean Corpuscular Haemoglobin) darah sapi bali yang dipelihara berbasis organik. Sistem pemeliharaan berbasis organik adalah manajemen pemberian pakan yang berasal dari lingkungan serta tidak menggunakan pestisida atau zat kimia lainnya. Nilai MCV, MCH dan MCHC darah sapi bali diukur dengan Veterinary hematology analyzer. Hasil penelitian menunjukan, nilai dari MCHC sebesar 39,17%/dl, MCV sebesar 48,44 fl dan nilai dari MCH sebesar 18,69pg. Dapat disimpulkan rerata nilai tersebut masih dalam batas normal nilai indeks eritrosit sapi pada umumnya.

scholarly journals Cogongrass (Imperata cylindrical L.) Roots Ethanol Extract to Improve Hematological Profile in Carbon Tetrachloride-Injection Mice Model

2020 ◽  
Vol 8 (3) ◽  
Author(s):  
Anisah Dahlan ◽  
Fitria Hariati Ramdhani ◽  
Neni Anggraeni ◽  
Irma Melyani Puspitasari ◽  
Mirasari Putri ◽  
...  
Keyword(s):  
Carbon Tetrachloride ◽  
Mean Corpuscular Volume ◽  
Hemoglobin Concentration ◽  
Ethanol Extract ◽  
Imperata Cylindrica ◽  
Mean Corpuscular Hemoglobin ◽  
Corpuscular Volume ◽  
Mean Corpuscular Hemoglobin Concentration ◽  
Corpuscular Hemoglobin ◽  
Hematological Profile

Carbon tetrachloride (CCL4) is widely used in industry, toxic to the environment and humans, and most often used as a model of acute liver damage and liver fibrosis in experimental animals. Liver damage can deteriorate the hematological profile. The roots of cogongrass (Imperata cylindrica L.) have been used as traditional medicine due to its antioxidant activity. This study was conducted at the Faculty of Medicine, Universitas Padjadjaran, from January to March 2019. The study aimed to investigate whether the cogongrass roots ethanol extract (CGRE) can ameliorate the disturbance in the hematological profile in acute CCl4-injected mice. CGRE in dose 150 and 200 mg/kgBW was given orally to mice for four weeks before intraperitoneal injection of CCl4 1 mL/kgBW in olive oil (1:1 v/v). After 48 hours, mice were sacrificed, and the whole blood was drawn for hematological analysis. As a result, mean corpuscular volume (MCV) was reduced in CCl4-induction mice treated with CGRE in dose 150 mg/kgBW (49.25±3.06 vs 43.38±2.13 fl, p<0.05). This condition was followed by the improved hematocrit (Hct) and mean corpuscular hemoglobin concentration (MCHC). Platelet and platelet crit (Pct) levels were tended to decrease in CCl4-induction mice treated with CGRE in dose 150 mg/kgBW. In conclusion, CGRE dose 150 mg/kg BW can improve MCV, Hct, MCHC, platelet, and Pct in CCl4-injection mice. The antioxidant level in CGRE might facilitate it. EKSTRAK ETANOL AKAR ALANG-ALANG (IMPERATA CYLINDRICAL L.) MEMPERBAIKI PROFIL HEMATOLOGI PADA MENCIT YANG DIINJEKSI CARBON TETRACHLORIDECarbon tetrachloride (CCL4) banyak digunakan pada industri, bersifat toksik bagi lingkungan dan manusia, serta sering digunakan pada hewan coba untuk kerusakan liver akut dan fibrosis. Kerusakan liver dapat menyebabkan gangguan profil hematologi. Akar alang-alang (Imperata cylindrica L.) telah digunakan sebagai obat tradisional karena memiliki aktivitas antioksidan. Penelitian ini dilakukan di Fakultas Kedokteran Universitas Padjadjaran pada bulan Januari hingga Maret 2019. Tujuan penelitian ini adalah meneliti apakah ekstrak etanol akar alang-alang dapat memperbaiki gangguan profil hematologi pada mencit yang diinjeksi CCL4 secara akut. Ekstrak etanol akar alang-alang (EEAA) dosis 150 dan 200 mm/kgBB diberikan per oral kepada mencit selama empat minggu sebelum injeksi intraperitoneal CCl4 1 mL/kgBB yang dilarutkan dalam minyak zaitun (1:1 v/v). Setelah 48 jam, mencit dikorbankan dan diambil darahnya untuk pemeriksaan hematologi. Sebagai hasil, mean corpuscular volume (MCV) menurun pada mencit yang diinduksi CCl4 dengan perlakuan EEAA 150 mg/kgBB (49,25±3,06vs 43,38±2,13 fl, p<0,05). Keadaan ini diikuti dengan perbaikan hematokrit (Hct) dan mean corpuscular hemoglobin concentration (MCHC). Kadar platelet dan platelet crit (Pct) cenderung menurun pada mencit yang diinduksi CCl4 dengan perlakuan EEAA 150 mg/kgBB. Sebagai simpulan, EEAA dosis 150 mg/kgBB dapat memperbaiki MCV, Hct, MCHC, platelet, dan Pct pada mencit yang diinjeksi CCL4. Kemungkinan difasilitasi oleh antioksidan pada EEAA.

scholarly journals Inaccuracy in automated measurement of hematocrit and corpuscular indices in the presence of severe hyperglycemia

Blood ◽  
1981 ◽  
Vol 57 (6) ◽  
pp. 1065-1067
Author(s):  
JA Strauchen ◽  
W Alston ◽  
J Anderson ◽  
Z Gustafson ◽  
LF Fajardo
Keyword(s):  
Blood Glucose ◽  
Mean Corpuscular Volume ◽  
Hemoglobin Concentration ◽  
Mean Corpuscular Hemoglobin ◽  
Corpuscular Volume ◽  
Automated Measurement ◽  
Mean Corpuscular Hemoglobin Concentration ◽  
Corpuscular Hemoglobin ◽  
Hyperosmolar Glucose

Because we recently observed two patients with severe diabetic hyperglycemia and spuriously elevated electronically determined hematocrit and mean corpuscular volume (MCV), we investigated the effect of hyperglycemia on two popular automated hematology systems, the Coulter S and Ortho ELT-8. Marked hyperglycemia (blood glucose 800-- 2000 mg/dl) caused consistent overestimation of the electronically determined MCV compared to that derived from a simultaneous spun microhematocrit. The resultant overestimation and underestimation, respectively, of the derived values for hematocrit and mean corpuscular hemoglobin concentration may be clinically misleading. The mechanism of MCV elevation in hyperglycemia appears to be swelling of hyperosmolar glucose “loaded” erythrocytes when diluted into “isotonic” counting medium. This effect is readily circumvented by determination of a spun microhematocrit.

scholarly journals 725. Complete Blood Count Values Vary in Degree of Change with Day of Fever in Children with Dengue Fever

2021 ◽  
Vol 8 (Supplement_1) ◽  
pp. S461-S462
Author(s):  
Melissa E Day ◽  
Miguel E Mejia Sang ◽  
Yonairy Collado Puello ◽  
Elvira J Diaz Brockmans ◽  
Stephanie Rivera Defillo ◽  
...  
Keyword(s):  
Dominican Republic ◽  
Blood Cell ◽  
Mean Corpuscular Volume ◽  
Blood Count ◽  
Complete Blood Count ◽  
Hemoglobin Concentration ◽  
Mean Corpuscular Hemoglobin ◽  
Corpuscular Volume ◽  
Mean Corpuscular Hemoglobin Concentration ◽  
Corpuscular Hemoglobin

Abstract Background Dengue fever (DF) is an acute viral disease which can lead to severe illness, including dengue hemorrhagic fever, marked by thrombocytopenia and hemolytic anemia, as well as end-organ damage. Despite the well-known presentation and prevalence, changes in hematologic markers across the DF course have not been well-described in children. We sought to investigate the association of clinical laboratory values over time with dengue disease progression and outcome in a pediatric population in the Dominican Republic. Methods Pediatric participants were enrolled at Hospital Infantil Dr. Robert Reid Cabral in Santo Domingo, Dominican Republic, in a prospective, observational case-based study. Laboratory values, including complete blood count (CBC) indices and dengue titer results, were collected over the course of hospital stay. Using linear mixed models, we assessed whether 13 different CBC values and time trajectories differed by dengue status, including age and sex as covariates. To account for multiple testing, p≤0.0033 was considered significant. Results A total of 575 children ages 0 to 211 months met inclusion criteria; 51.8% (n=298) were male, and the median (IQR) age was 59 (14-93) months. Eighty-two percent (n=472) of participants had DF. CBC values across days 1 to 10 of fever in those with and without DF are depicted in Figure 1. Those with DF showed levels dropping more quickly across days of fever for hematocrit and hemoglobin (p≤ 0.002), with a more rapid decline in those with severe DF (p &lt; 0.0001). Those with DF had levels increasing more quickly for mean corpuscular hemoglobin concentration (MCHC), monocyte number, and white blood cell counts (p ≤ 0.003), with those with severe DF having a more rapid increase (p &lt; 0.001). The direction of the change across time differed by DF status for mean corpuscular volume and red blood cell distribution width (RDW) (p ≤ 0.0003), with those with severe DF showing an increase in RDW across day of fever (p= 0.0004). Figure 1. CBC values across day of fever in dengue (blue) and non-dengue (purple) patients. The graph above depicts the following CBC values across day of fever in dengue (blue) and non-dengue (purple) patients: a) white blood cell (WBC) count, b) platelet count, c) monocyte number, d) hemoglobin, e) mean corpuscular hemoglobin concentration (MCHC), and f) mean corpuscular volume (MCV). Values with an asterisk (*) represent significant values (p &lt; 0.0033). Conclusion The trajectory of CBC measures differs between those with and without DF, despite similar clinical presentations. These laboratory differences may facilitate a better understanding of the clinical course of DF and may aid in earlier identification of DF in resource-limited settings. Disclosures Elizabeth P. Schlaudecker, MD, MPH, Pfizer (Grant/Research Support)Sanofi Pasteur (Advisor or Review Panel member)

Hemoglobin Profiles and Hematologic Features of Thalassemic Newborns: Application to Screening of α-Thalassemia 1 and Hemoglobin E

2008 ◽  
Vol 132 (11) ◽  
pp. 1739-1745
Author(s):  
Jaruwan Tritipsombut ◽  
Kanokwan Sanchaisuriya ◽  
Supan Fucharoen ◽  
Goonnapa Fucharoen ◽  
Nirut Siriratmanawong ◽  
...  
Keyword(s):  
Mean Corpuscular Volume ◽  
Cost Effective ◽  
Screening Methods ◽  
Mean Corpuscular Hemoglobin ◽  
Corpuscular Volume ◽  
Corpuscular Hemoglobin ◽  
Hemoglobin E ◽  
Polymerase Chain ◽  
Blood Specimens ◽  
Simple Screening

Abstract Context.—Thalassemia and hemoglobinopathies are major public health problems worldwide. To establish a cost-effective screening tool for newborns in regions where the incidence of these disorders is significant, study of the hemoglobin and hematologic features of normal and thalassemic newborns is necessary. Objective.—To study hemoglobin and hematologic characteristics of normal and various thalassemic newborns and to assess the effectiveness of simple screening methods for α-thalassemia 1 and hemoglobin E. Design.—Study was made of 402 cord blood specimens collected from unrelated Thai individuals. Hematologic parameters and hemoglobin profiles were determined. Thalassemia mutations were identified using polymerase chain reaction–related techniques. Results.—As many as 178 subjects (44.3%) were found to carry thalassemia genes with 18 different genotypes. All forms of α-thalassemia including double heterozygote for hemoglobin E and α-thalassemia showed significant reduction in hemoglobin, mean corpuscular volume, and mean corpuscular hemoglobin with increasing trend of red blood cell as compared with a non–α-thalassemic group. Although heterozygous hemoglobin E and β-thalassemia showed no hematologic difference from nonthalassemic group, heterozygous α-thalassemia 1 including those with hemoglobin E showed significant increase in hemoglobin Bart level. Conclusions.—Based on these findings, effective primary screening with 100% accuracy for α-thalassemia 1 and hemoglobin E in newborns in the region could be carried out using mean corpuscular volume less than 95 fL, mean corpuscular hemoglobin less than 30 pg, or hemoglobin Bart greater than 8.0% and hemoglobin E greater than 0.5%, respectively.

scholarly journals Red blood cell volume as a predictor of fatal reactions in cattle infected with Theileria parva Katete

2007 ◽  
Vol 74 (1) ◽  
Author(s):  
P. Fandamu ◽  
T. Marcotty ◽  
J.R.A. Brandt ◽  
L. Duchateau ◽  
N. Speybroeck ◽  
...  
Keyword(s):  
Blood Cell ◽  
Red Blood Cells ◽  
Cell Volume ◽  
Red Blood Cell ◽  
Packed Cell Volume ◽  
Blood Cells ◽  
Mean Corpuscular Volume ◽  
Corpuscular Volume ◽  
Theileria Parva ◽  
Fatal Reaction

A comparison of mean corpuscular volume (MCV) and packed cell volume (PCV) was made between cattle undergoing lethal and non-lethal reactions following experimental infections with the apicomplexan protozoa, Theileria parva Katete. This work confirmed that anaemia occurs in infected animals. However, the fall in PCV was steeper in lethal reactions compared to non-lethal reactions. Our results show that animals with initially lower MCV values are more prone to fatal reaction, despite having normal PCV profiles. The study also found that small red blood cells are more likely to be infected with T. parva. These findings suggest that animals with a higher proportion of small red blood cells in circulation will be more likely to succumb to T. parva infections. The potential for using MCV as a predictor of the outcome of infection challenge is discussed.

scholarly journals Evaluation of Erythrocyte Indices in Newborn According to Gestational Age

2018 ◽  
Vol 42 (2) ◽  
pp. 58-61
Author(s):  
Jesmeen Morshed ◽  
Mohammad Kabirul Islam ◽  
Sanjoy Kumer Day ◽  
Mahbub Mutanabbi ◽  
Mohammod Shahidullah
Keyword(s):  
Gestational Age ◽  
Mean Corpuscular Volume ◽  
Mean Corpuscular Hemoglobin ◽  
Corpuscular Volume ◽  
Corpuscular Hemoglobin ◽  
Distribution Width ◽  
Erythrocyte Indices ◽  
Preterm Group ◽  
Term Newborns ◽  
Rbc Count

Background: The normal hematological values in newborns differ significantly from those of infants, older children and adults. In our observation, the values of the newborn babies vary according to the gestational age. At birth the hemoglobin, hematocrit, mean corpuscular volume and mean corpuscular hemoglobin of term newborns are significantly higher than those of older infants and children, and in preterm newborns the differences are even more pronounced. The objective of this study is to evaluate the erythrocyte indices in preterm and term newborns at birth.Methodology: This cross sectional study was conducted in the department of Neonatology in BSMMU from May 2014 to April 2015. A total of 86 newborns; 48 term and 38 preterm were included in the study. Newborns were divided into two groups- term group and preterm group. Erythrocyte indices: hemoglobin (Hb), hematocrit (Hct), red blood cell (RBC) count, mean corpuscular volume (MCV), mean corpuscular hemoglobin (MCH), mean corpuscular hemoglobin concentration (MCHC) and red cell distribution width (RDW) were estimated from cord blood immediately after birth.Results: Mean hemoglobin level in term group was 15.65±1.04g/dl and preterm group was 15.21±0.93g/dl; this difference was statistically significant (p<0.05). Mean hematocrit value was significantly higher in term group (47.27%) than preterm group (46.10%) (p< 0.05). Mean MCH in term group was 34.49 pg and preterm group was 35.83 pg; this difference was statistically significant (p<0.05). Mean RBC count in term group was 4.47 million/cmm and preterm group was 4.35 million/cmm. Mean MCV was higher in preterm group (107.70 fl) than term group (104.58 fl): Mean MCHC was higher in preterm group (33.34g/dl) than term group (33.0g/dl); Mean RDW in term group was 18.18% and in preterm group was 18.58%. These differences were not statistically significant (p>0.05).Conclusion: This study concluded that erythrocyte indices of all newborns are not same; these differ according to gestational age.Bangladesh J Child Health 2018; VOL 42 (2) :58-61

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