ANALYSIS OF A NOVEL METHOD FOR INHIBITING RUNAWAY REACTION VIA PROCESS MODELING

2012 ◽  
pp. 107-130
Author(s):  
HELEN H. LOU ◽  
SANJEEV DUSIJA ◽  
XIANG LI ◽  
JOHN L. GOSSAGE ◽  
JACK. R. HOPPER
Keyword(s):  
Process Modeling ◽  
Runaway Reaction ◽  
Novel Method

Ontology-Based Framework for Quality in Configurable Process Models

2020 ◽  
pp. 464-478
Author(s):  
Loubna El Faquih ◽  
Mounia Fredj
Keyword(s):  
Business Process ◽  
Process Modeling ◽  
Process Model ◽  
Business Processes ◽  
Research Work ◽  
Process Models ◽  
Novel Method ◽  
Ontology Languages ◽  
Variability Management

In recent years, business process modeling has increasingly drawn the attention of enterprises. As a result of the wide use of business processes, redundancy problems have arisen and researchers introduced the variability management, in order to enhance the business process reuse. The most approach used in this context is the Configurable Process Model solution, which consists in representing the variable and the fixed parts together in a unique model. Due to the increasing number of variants, the configurable models become complex and incomprehensible, and their quality is therefore impacted. Most of research work is limited to the syntactic quality of process variants. The approach presented in this paper aims at providing a novel method towards syntactic verification and semantic validation of configurable process models based on ontology languages. We define validation rules for assessing the quality of configurable process models. An example in the e-healthcare domain illustrates the main steps of our approach.

A Graph Grammar Approach to Generate Neural Network Topologies

2007 ◽  
Author(s):  
Chaitanya Vempati ◽  
Matthew I. Campbell
Keyword(s):  
Neural Network ◽  
Neural Networks ◽  
Process Modeling ◽  
Graph Transformation ◽  
Graph Grammar ◽  
Transformation Rules ◽  
The Neural Network ◽  
Network Topologies ◽  
Novel Method ◽  
Defining Graph

Neural networks are increasingly becoming a useful and popular choice for process modeling. The success of neural networks in effectively modeling a certain problem depends on the topology of the neural network. Generating topologies manually relies on previous neural network experience and is tedious and difficult. Hence there is a rising need for a method that generates neural network topologies for different problems automatically. Current methods such as growing, pruning and using genetic algorithms for this task are very complicated and do not explore all the possible topologies. This paper presents a novel method of automatically generating neural networks using a graph grammar. The approach involves representing the neural network as a graph and defining graph transformation rules to generate the topologies. The approach is simple, efficient and has the ability to create topologies of varying complexity. Two example problems are presented to demonstrate the power of our approach.

The removal and morphology of intact biofilms from implanted venous access devices

1995 ◽  
Vol 53 ◽  
pp. 1020-1021
Author(s):  
M.A. Gregory ◽  
G.P. Hadley
Keyword(s):  
Patient Selection ◽  
Surgical Oncology ◽  
Venous Access ◽  
Common Procedure ◽  
Indwelling Catheters ◽  
Careful Patient ◽  
Novel Method ◽  
The Subject ◽  
Vascular Catheters ◽  
Venous Access Devices

The insertion of implanted venous access systems for children undergoing prolonged courses of chemotherapy has become a common procedure in pediatric surgical oncology. While not permanently implanted, the devices are expected to remain functional until cure of the primary disease is assured. Despite careful patient selection and standardised insertion and access techniques, some devices fail. The most commonly encountered problems are colonisation of the device with bacteria and catheter occlusion. Both of these difficulties relate to the development of a biofilm within the port and catheter. The morphology and evolution of biofilms in indwelling vascular catheters is the subject of ongoing investigation. To date, however, such investigations have been confined to the examination of fragments of biofilm scraped or sonicated from sections of catheter. This report describes a novel method for the extraction of intact biofilms from indwelling catheters.15 children with Wilm’s tumour and who had received venous implants were studied. Catheters were removed because of infection (n=6) or electively at the end of chemotherapy.

Longitudinal Changes in Individual BrainAGE in Healthy Aging, Mild Cognitive Impairment, and Alzheimer’s Disease

GeroPsych ◽  
2012 ◽  
Vol 25 (4) ◽  
pp. 235-245 ◽  
Author(s):  
Katja Franke ◽  
Christian Gaser
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Healthy Aging ◽  
Brain Aging ◽  
Elderly Subjects ◽  
Additional Increase ◽  
Longitudinal Changes ◽  
Novel Method ◽  
The Brain

We recently proposed a novel method that aggregates the multidimensional aging pattern across the brain to a single value. This method proved to provide stable and reliable estimates of brain aging – even across different scanners. While investigating longitudinal changes in BrainAGE in about 400 elderly subjects, we discovered that patients with Alzheimer’s disease and subjects who had converted to AD within 3 years showed accelerated brain atrophy by +6 years at baseline. An additional increase in BrainAGE accumulated to a score of about +9 years during follow-up. Accelerated brain aging was related to prospective cognitive decline and disease severity. In conclusion, the BrainAGE framework indicates discrepancies in brain aging and could thus serve as an indicator for cognitive functioning in the future.

Novel method of mitral annular enlargement for implantation of an oversized mitral valve prosthesis

2014 ◽  
Vol 62 (S 02) ◽  
Author(s):  
J. Photiadis ◽  
M. Musci ◽  
O. Miera ◽  
S. Ovroutski ◽  
A. Mekkawy ◽  
...  
Keyword(s):  
Mitral Valve ◽  
Valve Prosthesis ◽  
Mitral Valve Prosthesis ◽  
Novel Method

A Novel Method for the Rapid Purification of Human and Rat Fibrin(OGEN) Degradation Products in High Yields

1979 ◽  
Author(s):  
W. Nieuwenhuizen ◽  
I. A. M. van Ruijven-Vermeer ◽  
F. Haverkate ◽  
G. Timan
Keyword(s):  
Degradation Products ◽  
Complete Separation ◽  
Purification Method ◽  
Amino Terminal ◽  
Novel Method ◽  
Rapid Purification ◽  
The One ◽  
High Yields ◽  
Size Heterogeneity ◽  
D Dimer

A novel method will be described for the preparation and purification of fibrin(ogen) degradation products in high yields. The high yields are due to two factors. on the one hand an improved preparation method in which the size heterogeneity of the degradation products D is strongly reduced by plasmin digestion at well-controlled calcium concentrations. At calcium concentrations of 2mM exclusively D fragments, M.W.= 93-000 (Dcate) were formed; in the presence of 1OmM EGTA only fragments M.W.= 80.000 (D EGTA) were formed as described. on the other hand a new purification method, which includes Sephadex G-200 filtration to purify the D:E complexes and separation of the D and E fragments by a 16 hrs. preparative isoelectric focussing. The latter step gives a complete separation of D (fragments) (pH = 6.5) and E fragments (at pH = 4.5) without any overlap, thus allowing a nearly 100% recovery in this step. The overall recoveries are around 75% of the theoretical values. These recoveries are superior to those of existing procedures. Moreover the conditions of this purification procedure are very mild and probably do not affect the native configuration of the products. Amino-terminal amino acids of human Dcate, D EGTA and D-dimer are identical i.e. val, asx and ser. in the ratgly, asx and ser were found. E 1% for rat Dcate=17-8 for rat D EGTA=16.2 and for rat D- dimer=l8.3. for the corresponding human fragments, these values were all 20.0 ± 0.2.

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