Inhibitory Effects of Anti-SARS Traditional Chinese Medicines on the UV Irradiation of λ-Lysogen

2006 ◽  
Vol 34 (01) ◽  
pp. 147-155 ◽  
Author(s):  
Yaqiong Li ◽  
Jing Li ◽  
Chengxiang Fang

By using λ-lysogen as a model, the inhibitory effects of anti-severe acute respiratory syndrome (SARS) traditional Chinese medicines (TCMs) prescription I on the UV irradiation were investigated in this present study. It was found that the prescription I possessed obvious inhibitory effects on the UV induction of λ-lysogen, the inhibitory rate reaching 83.87%. Among five medicinal herbs prescribed in that formula, Herba Patriniae, Radix Astragali and Radix Glycyrrhizae played important roles. When these three herbs were eliminated from the recipe separately, the inhibitory effects were prominently decreased. If only one of these five medicinal herbs was added into the medium of λ-lysogen, the inhibitory rates ranged from 27.0% ~ 45.0%. By electron spin resonance (ESR) detection, we found that the prescription I , Herba Patriniae and other main herbs in that recipe, could quench effectively the free radicals generated in the process of λ-lysogenic cells by UV. These results provide a novel idea for further studying the pharmacology of TCM and exploring the mechanism of SARS virus infection.

2003 ◽  
Vol 42 (Part 1, No. 2A) ◽  
pp. 428-433 ◽  
Author(s):  
Hideo Sato ◽  
Atsushi Tani ◽  
Motoji Ikeya

2020 ◽  
Vol 2020 ◽  
pp. 1-12 ◽  
Author(s):  
Kai-Jian Fan ◽  
Yun-Wu Li ◽  
Jing Wu ◽  
Jun Li ◽  
Jun Zhang ◽  
...  

Fufang Shatai Heji (STHJ) is a mixture of traditional Chinese medicines, such as Radix Adenophorae, Radix Pseudostellariae, and Radix Astragali. STHJ is commonly used to treat diseases caused by low immune function, for example, Sjögren’s syndrome (SS). The primary objective of this study was to assess the immunopotentiating effect of STHJ using an immunosuppressive mouse model receiving cyclophosphamide (CTX). Following CTX treatment, STHJ was administered by oral gavage for 30 consecutive days. The percentage of specific lymphocyte subpopulations in the spleen was measured by flow cytometry. Levels of inflammatory factors in serum were detected by enzyme-linked immunosorbent assays (ELISAs). The administration of STHJ significantly elevated thymus and spleen indices, increased B cell and natural killer (NK) cell activities, and decreased CD8+ T, CD8+CD122+ T, NKT, and γδT cell activities in the CTX-treated mice. In addition, STHJ upregulated the expression of interleukin- (IL-) 2, IL-6, and tumor necrosis factor-α (TNF-α) and downregulated IL-10 expression in CTX-treated mice. In conclusion, STHJ effectively remitted CTX-induced immunosuppression by modulating the balance of lymphocyte subsets and cytokines. Our results suggest STHJ treatment could be used as an effective therapeutic approach to improve immune function in patients with low immunity.


1963 ◽  
Vol 18 (7) ◽  
pp. 818-822 ◽  
Author(s):  
F. Matossi ◽  
A. Räuber ◽  
F. W. Küpper

Different kinds of doping in ZnS crystals lead to characteristic ion charge conversions of iron and chromium ions. This is shown by the esr of Fe3+ and Cr+ ions and the behavior of the esr lines with respect to illumination with uv. Doping with CuS gives Fe3+ ions; ZnS doped with Zinc or halogen shows Cr+ resonance after uv irradiation. The ion charge conversions are interpreted by changes in the FERMI level. Iron in ZnS crystals can be converted completely into Fe3+ through tempering for 24 hours at 800°C with CuS in evacuated quartz ampullae if the iron contents is not greater than about 10-3 % by weight. Fe3+ can then be determined quantitatively with electron spin resonance for concentrations between 10-3 and about 106% by weight. Tempering in sulphur vapor at 1050°C produces from the originally cubic and submicroscopically twinned crystals such that are hexagonal in the extent of about 60%.


2012 ◽  
Vol 535-537 ◽  
pp. 1126-1132 ◽  
Author(s):  
Sheng Bang Zhang ◽  
Xiao Wu Ji ◽  
Cui Ping Liu

Abstract: Determination of multi-elements were studied in the food cooked with medicinal herbs Ophiopogon japonicus(OJ) and Lotus seeds by ICP-AES after HNO3-H2O2 digestion with microwave. The average recoveries are in 91.7%~ 102.4% of As, Cr, Se, Cd, Cu, Mn, Zn, Al, Ba, Fe, Ni, respectively. The relative standard deviation(RSD)is less than 2.8% except Al (9.4%)and detection limit is in the range of 0. 10µg/L ~8.5µg/L except Al (79.6µg/L). The difference was very obvious(p0.001,except As) that the elements’ content on the comparison OJ with Lotus seeds. There was rich of the trace elements Cu, Zn. The harmful element Al was on the high value(214.7µg/g)in the OJ. It is of important significance to assess the value of the food cooked with medicinal herbs by determination of multiply elements in Lotus seeds, and OJ with ICP-AES. Keyword: multi-elements, the trace elements, the harmful elements, Ophiopogon japonicus, Lotus seeds, ICP-AES


Sign in / Sign up

Export Citation Format

Share Document