CASE REPORT: PSITTACINE POX VIRUS INFECTION IN AGAPORNIS ROSEICOLLIS

2017 ◽  
Vol 43 (02) ◽  
pp. 85-88
Author(s):  
Dan-Yuan Lo ◽  
Jih-Ching Yeh ◽  
Chris Chi ◽  
Chiou-Lin Chen ◽  
Ming-Huang Chang ◽  
...  
Keyword(s):  
Case Report ◽  
Inclusion Bodies ◽  
Nasal Bone ◽  
Infected Bird ◽  
Transmission Electron ◽  
Stratum Spinosum ◽  
Bird Beak ◽  
Intracytoplasmic Inclusion Bodies ◽  
Cutaneous Form ◽  
Sporadic Disease

This case report describes the outbreak of a combined diphtheritic and cutaneous form of psittacine pox in Agapornis roseicollis in Tainan, Taiwan in June, 2015. Scabs were observed on the legs and eyelids, the bases of beaks, and diphtheritic mucous membranes were observed on the upper digestive and respiratory tracts, too. In histopathological examinations, epitheliums and osteoblasts in nasal bone contained eosinophilic intracytoplasmic inclusion bodies in stratum spinosum. The infected bird beak tissue exhibited brick-shaped virions with biconcave dumbbell-shaped core by transmission electron microscopy. From the previous reports, psittacine pox virus in Taiwan may be more virulent than other reported strains and still occurs as a sporadic disease in Taiwan. This is the first report in the world discussed about the infection of osteoblast by poxvirus.

scholarly journals A Patient with Proximal Myotonic Myopathy and Parkinsonism

2002 ◽  
Vol 29 (2) ◽  
pp. 188-190 ◽  
Author(s):  
Kon Chu ◽  
Jin-Whan Cho ◽  
Eun-Chol Song ◽  
Beom S. Jeon
Keyword(s):  
Case Report ◽  
Myotonic Dystrophy ◽  
Inclusion Bodies ◽  
Neurodegenerative Disorder ◽  
Case Reports ◽  
Proximal Myotonic Myopathy ◽  
Intracytoplasmic Inclusion Bodies ◽  
Gene Study ◽  
Stooped Posture

Abstract:Introduction:There are two case reports of patients who had proximal myotonic myopathy (PROMM) / myotonic dystrophy (DM) Type 1 and parkinsonism. The combination of myotonic myopathy and parkinsonism is so rare that it may appear to be just a coincidence. However, previous neuropathological examinations of patients who had myotonic dystrophy showed that there were intracytoplasmic inclusion bodies in the nigra and striatum, which raises the possibility that myotonic myopathy may be associated with parkinsonism. In this report we describe a patient with PROMM and a clinically definite parkinsonism to highlight this possibility.Case Report:A 65-year-old man developed proximal muscle weakness, myotonia and atrophy around the age of 55 and was diagnosed as having PROMM at the age of 62. Needle electromyography and muscle biopsy supported the diagnosis. A gene study of the DM Type 1 showed a normal CTG repeat length. At age 63, he developed rest tremor, bradykinesia, hypomimia, stooped posture, and gait disturbance. The postural instability worsened rapidly. The tremor and rigidity were much worse in his right side, where myotonia was more severe. Levodopa therapy was only partially effective.Conclusion:This is a case report of a patient with PROMM that shows an association with a rapidly progressive form of parkinsonism. We suggest that this may be a novel form of a neurodegenerative disorder, which we name ‘Parkinsonism- Myotonic Myopathy-Complex’.

Microprobe analysis of inclusion bodies related to two benzofuran derivatives

1987 ◽  
Vol 45 ◽  
pp. 672-673
Author(s):  
T. L. Benning ◽  
P. Ingram ◽  
J. D. Shelburne
Keyword(s):  
Inclusion Bodies ◽  
Uranyl Acetate ◽  
Multiple Organ ◽  
High Dose ◽  
En Bloc ◽  
Tissue Samples ◽  
Transmission Electron ◽  
Organ Systems ◽  
Dense Inclusion ◽  
Melanin Complex

Two benzofuran derivatives, chlorpromazine and amiodarone, are known to produce inclusion bodies in human tissues. Prolonged high dose chlorpromazine therapy causes hyperpigmentation of the skin with electron-dense inclusion bodies present in dermal histiocytes and endothelial cells ultrastructurally. The nature of the deposits is not known although a drug-melanin complex has been hypothesized. Amiodarone may also cause cutaneous hyperpigmentation and lamellar lysosomal inclusion bodies have been demonstrated within the cells of multiple organ systems. These lamellar bodies are believed to be the product of an amiodarone-induced phospholipid storage disorder. We performed transmission electron microscopy (TEM) and energy dispersive x-ray microanalysis (EDXA) on tissue samples from patients treated with these drugs, attempting to detect the sulfur atom of chlorpromazine and the iodine atom of amiodarone within their respective inclusion bodies.A skin biopsy from a patient with hyperpigmentation due to prolonged chlorpromazine therapy was fixed in 4% glutaraldehyde and processed without osmium tetroxide or en bloc uranyl acetate for Epon embedding.

scholarly journals Investigation of Lethal Concurrent Outbreak of Chlamydiosis and Pigeon Circovirus in a Zoo

Animals ◽  
2021 ◽  
Vol 11 (6) ◽  
pp. 1654
Author(s):  
Wei-Tao Chen ◽  
Chin-Ann Teng ◽  
Cheng-Hsin Shih ◽  
Wei-Hsiang Huang ◽  
Yi-Fan Jiang ◽  
...  
Keyword(s):  
Disease Outbreaks ◽  
Chlamydia Psittaci ◽  
Bursa Of Fabricius ◽  
Chain Reactions ◽  
Renal Epithelium ◽  
Polymerase Chain Reactions ◽  
Transmission Electron ◽  
Intracytoplasmic Inclusion Bodies ◽  
Polymerase Chain ◽  
Streptopelia Orientalis

During the spring, an outbreak of sudden death involving 58 birds occurred in a zoo. Histopathological examinations revealed variable numbers of intracytoplasmic basophilic microorganisms in the macrophages, hepatocytes, and renal epithelium of most birds, along with occasional botryoid intracytoplasmic inclusion bodies within histiocytes in the bursa of Fabricius. Based on the results of histopathological examinations, immunohistochemical staining, transmission electron microscopy, and polymerase chain reactions, genotype B Chlamydia psittaci infection concurrent with pigeon circovirus (PiCV) was diagnosed. A retrospective survey, including two years before the outbreak and the outbreak year, of C. psittaci and PiCV infections of dead birds in the aviaries, revealed that the outbreak was an independent episode. The findings of this study indicate that concurrent infection with C. psittaci and PiCV might lead to lethal outbreaks of chlamydiosis, particularly Streptopelia orientalis. In addition, persistently monitoring both pathogens and identifying potential PiCV carriers or transmitters might also help prevent lethal disease outbreaks.

Intracytoplasmic inclusion bodies in the chondrocytes of type I lethal achondrogenesis

1976 ◽  
Vol 7 (6) ◽  
pp. 667-673 ◽  
Author(s):  
Sheng-S. Yang ◽  
Kathleen P. Heidelberger ◽  
Jay Bernstein
Keyword(s):  
Inclusion Bodies ◽  
Type I ◽  
Intracytoplasmic Inclusion ◽  
Intracytoplasmic Inclusion Bodies

scholarly journals Rhinoplasty in a Patient with Nasal Bone Hypoplasia: A Case Report

2019 ◽  
Vol 12 (12) ◽  
pp. 99-104
Author(s):  
Farrokh Savaddar ◽  
Fatemeh Amirkanian ◽  
Enayatollah Noori ◽  
Sajad Rezvan ◽  
◽  
...  
Keyword(s):  
Case Report ◽  
Nasal Bone

Naturally Occurring Infectious Fibroma in the Domestic Rabbit

1973 ◽  
Vol 10 (6) ◽  
pp. 509-519 ◽  
Author(s):  
L. T. Pulley ◽  
J. N. Shively
Keyword(s):  
Tumor Cells ◽  
Inclusion Bodies ◽  
Inflammatory Cells ◽  
Naturally Occurring ◽  
Intracytoplasmic Inclusion ◽  
Domestic Rabbit ◽  
Cutaneous Tumor ◽  
Intracytoplasmic Inclusion Bodies ◽  
Vascular Channels ◽  
Domestic Rabbits

Infectious fibromas developed in eight domestic rabbits that were all kept in outside cages. Each rabbit had a single cutaneous tumor. Six of these tumors, which were studied by light microscopy, consisted of tumor cells resembling fibroblasts and large areas of inflammation. The overlying epidermis was hyperplastic and contained easily recognizable intracytoplasmic inclusion bodies. Inclusion bodies were also in subepithelial fibroma cells. Electron microscopy of three of these tumors revealed typical pox-virus inclusions, sites of viral replication, maturation, and mature particles in epithelial cells of the epidermis and in subepithelial tumor cells. Virus was not seen in inflammatory cells or leukocytes within vascular channels.

scholarly journals Morbilliviral Dermatitis in Seals

2001 ◽  
Vol 38 (6) ◽  
pp. 724-726 ◽  
Author(s):  
T. P. Lipscomb ◽  
M. G. Mense ◽  
P. L. Habecker ◽  
J. K. Taubenberger ◽  
R. Schoelkopf
Keyword(s):  
Inclusion Bodies ◽  
Marine Mammals ◽  
Skin Lesions ◽  
Basal Cells ◽  
Hooded Seal ◽  
Cystophora Cristata ◽  
Phoca Groenlandica ◽  
Phocine Distemper Virus ◽  
Intracytoplasmic Inclusion Bodies ◽  
Polymerase Chain

A juvenile female hooded seal ( Cystophora cristata) and a juvenile male harp seal ( Phoca groenlandica) stranded separately on the New Jersey (USA) coast and were taken to a marine mammal rehabilitation center. Both were lethargic and emaciated, had dermatitis, and died. Histologic skin lesions in the seals were similar and consisted of epidermal and follicular epithelial hyperplasia, hyperkeratosis, degeneration, and necrosis. The most distinctive finding was extensive syncytial zones bounded superficially by hyperkeratosis and deeply by hyperplastic basal cells. Eosinophilic intracytoplasmic inclusion bodies were present in epithelial cells. Morbilliviral antigen was demonstrated in the skin lesions by immunohistochemistry. Phocine distemper virus was detected in the skin by reverse transcription polymerase chain reaction and a phocine distemper virus-specific probe using the Southern blot technique. This is the first report of morbilliviral dermatitis in marine mammals.

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