Analytic study on the force transfer of full encapsulating rockbolts subjected to tensile force

Author(s):  
Jianhang Chen ◽  
Yiqiang Zhao ◽  
Hongbao Zhao ◽  
Junwen Zhang ◽  
Cun Zhang ◽  
...  
2012 ◽  
Vol 445 (1) ◽  
pp. 57-67 ◽  
Author(s):  
Yulia Shifrin ◽  
Vanessa I. Pinto ◽  
Abbas Hassanali ◽  
Pamma D. Arora ◽  
Christopher A. McCulloch

Cells in mechanically challenged environments cope with high-amplitude exogenous forces that can lead to cell death, but the mechanisms that mediate force-induced apoptosis and the identity of mechanoprotective cellular factors are not defined. We assessed apoptosis in NIH 3T3 and HEK (human embryonic kidney)-293 cells exposed to tensile forces applied through β1-integrins. Apoptosis was mediated by Rac-dependent activation of p38α. Depletion of Pak1 (p21-activated kinase 1), a downstream effector of Rac, prevented force-induced p38 activation and apoptosis. Rac was recruited to sites of force transfer by filamin A, which inhibited force-induced apoptosis mediated by Rac and p38α. We conclude that, in response to tensile force, filamin A regulates Rac-dependent signals, which induce apoptosis through Pak1 and p38.


2011 ◽  
Vol 94-96 ◽  
pp. 1838-1843
Author(s):  
Deng Yuan Zhu ◽  
Zhan Yong Yao ◽  
Yong Wei Zhang

Taking the advantages of groove pedestal and pier pedestal, a new type of pre-tensioned pedestal is constructed. The new pedestal makes full use of the deck (also the bottom formwork of the beam) to bear the tensile force so as to reduce the quantity of the pedestal construction. The new pedestal can adapt to variable geotechnical conditions by properly enlarge the arm of the turnover moment and the self-weight. The new pedestal is optimized through the bearing capacity analysis of the anti-overturning, the anti-slipping, the table anti-compressing, the force transfer plate, and the cross tie beams. The stress distribution of local bearing bracket is calculated by the finite element method so as to be reinforced accordingly. Based on practical application in some project, the new pedestal has the features of technical feasibility, security & reliability, affordability, and convenience in operation.


2011 ◽  
Author(s):  
Tyler Hunt ◽  
David Shwalb ◽  
Cameron Brown ◽  
Alayna Purdy ◽  
Jenna Flynn ◽  
...  

2006 ◽  
Author(s):  
Christine M. Smith ◽  
Kate Bell ◽  
Kevin Bettes ◽  
Emily Bushouse ◽  
Karlie Singleton
Keyword(s):  

2019 ◽  
Vol 4 (2) ◽  
Author(s):  
Nugroho Ahmad Riyadi

The aim of orthodontics treatment is normalization of teeth position in three planes, using various orthodontics appliance to reach the chepalometric standar and normal occlusion. Orthodontic treatment for dentoskeletal class II division 1 malocclusion in growing patients using myofunctional appliance may correct anteroposterior planes of mandibula. This study was a descriptive retrospective analytic study to look at the success of Orthodontic treatment for dentoskeletal class II division 1 in growing patients with myofunctional appliance using chepalometrics analysis Steiner value. The sample used in this study is chepalogram radiographic from patient with dentoskeletal class II division 1 malocclusion in growing patients before and after using myofunctional appliance in PPDGS orthodontics Clinic of Padjadjaran University. Statistic analysis were performed with pair t-test and Wilcoxon. Based on this study, it is concluded that orthodontic treatment with myofunctional appliance such as activator and twin block in growing patient with dentoskeletal class II division 1 malocclusion shows significant changes and compatibility with the normal criteria.


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