DEVELOPMENT OF HIGH-SPEED SWEPT-SOURCE OPTICAL COHERENCE TOMOGRAPHY SYSTEM AT 1320 nm

2009 ◽  
Vol 02 (01) ◽  
pp. 117-122 ◽  
Author(s):  
TONG WU ◽  
ZHIHUA DING ◽  
MINGHUI CHEN ◽  
LEI XU ◽  
GUOHUA SHI ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
High Speed ◽  
Calibration Method ◽  
Wave Number ◽  
Laser Source ◽  
Depth Range ◽  
Optical Coherence ◽  
Swept Source ◽  
Human Finger

A swept-source optical coherence tomography (SSOCT) system based on a high-speed scanning laser source at center wavelength of 1320 nm and scanning rate of 20 kHz is developed. The axial resolution is enhanced to 8.3 μm by reshaping the spectrum in frequency domain using a window function and a wave number calibration method based on a Mach-Zender Interferometer (MZI) integrated in the SSOCT system. The imaging speed and depth range are 0.04 s per frame and 3.9 mm, respectively. The peak sensitivity of the SSOCT system is calibrated to be 112 dB. With the developed SSOCT system, optical coherence tomography (OCT) images of human finger tissue are obtained which enable us to view the sweat duct (SD), stratum corneum (SC) and epidermis (ED), demonstrating the feasibility of the SSOCT system for in vivo biomedical imaging.

scholarly journals Laser Lens Size Measurement Using Swept-Source Optical Coherence Tomography

2020 ◽  
Vol 10 (14) ◽  
pp. 4936
Author(s):  
Pingping Jia ◽  
Hong Zhao ◽  
Yuwei Qin
Keyword(s):  
Optical Coherence Tomography ◽  
High Speed ◽  
Wave Number ◽  
Radius Of Curvature ◽  
Optical Coherence ◽  
Swept Source ◽  
Laser Focusing ◽  
Fitting Algorithm ◽  
Laser Confocal Microscope ◽  
Focusing Lens

A high-speed, high-resolution swept-source optical coherence tomography (SS-OCT) is presented for focusing lens imaging and a k-domain uniform algorithm is adopted to find the wave number phase equalization. The radius of curvature of the laser focusing lens was obtained using a curve-fitting algorithm. The experimental results demonstrate that the measuring accuracy of the proposed SS-OCT system is higher than the laser confocal microscope. The SS-OCT system has great potential for surface topography measurement and defect inspection of the focusing lens.

scholarly journals Polarization sensitive optical coherence tomography utilizing a buffered swept source laser

2017 ◽  
Vol 3 (2) ◽  
pp. 227-230
Author(s):  
Jonas Golde ◽  
Lars Kirsten ◽  
Edmund Koch
Keyword(s):  
Optical Coherence Tomography ◽  
High Speed ◽  
Single Mode ◽  
Single Mode Fiber ◽  
Fourier Domain ◽  
Optical Coherence ◽  
Swept Source ◽  
Finger Nail ◽  
Swept Source Oct ◽  
Human Finger

AbstractWe present an approach for polarization sensitive optical coherence tomography (PS-OCT) that solely requires a modification of the light source, a buffered swept source laser. For this purpose a single-mode fiber-based Fourier domain mode locked laser is extended by fourfold buffering with manual fiber polarization controllers to emit alternating sweep polarizations, while the polarization contrast calibration is realized by a high-speed polarimeter. As the introduced setup utilizes standard scanning and detection units, the proposed method is a promising way to enhance various swept source OCT systems by polarization sensitive imaging. Preliminary measurements of a human finger nail with different polarization contrasts demonstrate the feasibility of the concept.

scholarly journals High-speed imaging of human retina in vivo with swept-source optical coherence tomography

2006 ◽  
Vol 14 (26) ◽  
pp. 12902 ◽  
Author(s):  
H. Lim ◽  
M. Mujat ◽  
C. Kerbage ◽  
E. C. W. Lee ◽  
Y. Chen ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
High Speed ◽  
Human Retina ◽  
Optical Coherence ◽  
High Speed Imaging ◽  
Swept Source

scholarly journals Developments in Contact Lens Imaging: New Applications of Optical Coherence Tomography

2019 ◽  
Vol 9 (13) ◽  
pp. 2580
Author(s):  
Joanna Stachura ◽  
Małgorzata Seredyka-Burduk ◽  
Ilona Piotrowiak-Słupska ◽  
Magdalena Kaszuba-Modrzejewska ◽  
Jagoda Rzeszewska-Zamiara ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Contact Lens ◽  
High Speed ◽  
Contact Lenses ◽  
Tear Film ◽  
Laser Source ◽  
Optical Coherence ◽  
Cross Sectional ◽  
Swept Source ◽  
Swept Source Oct

Optical coherence tomography (OCT) is a high-speed and non-contact optical imaging technology widely used for noninvasive cross-sectional imaging of biological objects. Two main OCT technologies have been developed: time domain and Fourier domain technologies. The latter can be further divided into spectral domain OCT, which uses a broadband light source and a spectrometer as a detector, and swept source OCT, which employs a quickly-rotating laser source. Advances in OCT technology have made it one of the most helpful devices in ophthalmic practice. Fourier OCT has revolutionized imaging of the posterior segment of the eye, as well as of anterior structures and has enhanced the ability to diagnose and manage patients. It provides high-resolution information about the tear film, contact lens (CL), a qualitative and quantitative assessment of the anterior eye that is important in contact lens fitting, and allows possible eye surface changes while wearing contact lenses to be monitored. Potential swept source OCT technology applications include industrial processes of lens design and quality control. In this paper, we describe clinical applications and outline a variety of multifunctional uses of OCT in the field of refractive error correction with contact lenses.

scholarly journals Three-dimensional and high-speed swept-source optical coherence tomography for in vivo investigation of human anterior eye segments

2005 ◽  
Vol 13 (26) ◽  
pp. 10652 ◽  
Author(s):  
Yoshiaki Yasuno ◽  
Violeta Dimitrova Madjarova ◽  
Shuichi Makita ◽  
Masahiro Akiba ◽  
Atsushi Morosawa ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
High Speed ◽  
Three Dimensional ◽  
Optical Coherence ◽  
Swept Source

scholarly journals Quantitative Swept-Source Optical Coherence Tomography of Early Enamel Erosion in vivo

2017 ◽  
Vol 51 (4) ◽  
pp. 410-418 ◽  
Author(s):  
Rupert S. Austin ◽  
Maisalamah Haji Taha ◽  
Frederic Festy ◽  
Richard Cook ◽  
Manoharan Andiappan ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Healthy Volunteers ◽  
Orange Juice ◽  
Signal Intensity ◽  
Surface States ◽  
Enamel Surface ◽  
Optical Coherence ◽  
Swept Source ◽  
Water Rinsing

Swept-source optical coherence tomography (SS-OCT) shows potential for the in vivo quantitative evaluation of micro-structural enamel surface phenomena occurring during early erosive demineralization. This randomized controlled single-blind cross-over clinical study aimed to evaluate the use of SS-OCT for detecting optical changes in the enamel of 30 healthy volunteers subjected to orange juice rinsing (erosive challenge) in comparison to mineral water rinsing (control), according to wiped and non-wiped enamel surface states. Participants were randomly allocated to 60 min of orange juice rinsing (pH 3.8) followed by 60 min of water rinsing (pH 6.7) and vice versa, with a 2-week wash-out period. In addition, the labial surfaces of the right or left maxillary incisors were wiped prior to SS-OCT imaging. An automated ImageJ algorithm was designed to analyse the back-scattered OCT signal intensity (D) after orange juice rinsing compared to after water rinsing. D was quantified as the OCT signal scattering from the 33 µm sub-surface enamel, normalised by the total OCT signal intensity entering the enamel. The back-scattered OCT signal intensity increased by 3.1% (95% CI 1.1-5.1%) in the wiped incisors and by 3.5% (95% CI 1.5-5.5%) in the unwiped incisors (p < 0.0001). Wiping reduced the back-scattered OCT signal intensity by 1.7% (95% CI -3.2 to -0.3%; p = 0.02) in comparison to the unwiped enamel surfaces for both rinsing solutions (p = 0.2). SS-OCT detected OCT signal changes in the superficial sub-surface enamel of maxillary central incisor teeth of healthy volunteers after orange juice rinsing.

Swept source optical coherence tomography for in vivo imaging and vibrometry in the apex of the mouse cochlea

2015 ◽  
Author(s):  
Hee Yoon Lee ◽  
Patrick D. Raphael ◽  
Audrey K. Ellerbee ◽  
Brian E. Applegate ◽  
John S. Oghalai
Keyword(s):  
Optical Coherence Tomography ◽  
In Vivo Imaging ◽  
Optical Coherence ◽  
Swept Source
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