scholarly journals Optical design and simulation of an integrated OCT and video rigid laryngoscope

2020 ◽  
Vol 13 (03) ◽  
pp. 2040002
Author(s):  
Jiajing Kang ◽  
Xinyu Li ◽  
Mingming Wan ◽  
Jiahui Wang ◽  
Shanshan Liang ◽  
...  
Keyword(s):  
Low Cost ◽  
Optical Design ◽  
Field Of View ◽  
Light Transmittance ◽  
Gradient Index ◽  
Modulation Transfer ◽  
Common Path ◽  
Path Design ◽  
Relay Element ◽  
Integrated Optical

An integrated optical coherence tomography (OCT) and video rigid laryngoscope have been designed to acquire surface and subsurface tissue images of larynx simultaneously. The dual-modality system that is based on a common-path design with components as few as possible effectively maintains the light transmittance without compromising the imaging quality. In this paper, the field of view (FOV) of the system can reach [Formula: see text] by use of a gradient index (GRIN) lens as the relay element and a four-lens group as the distal objective, respectively. The simulation showed that the modulation transfer function (MTF) value in each FOV of the rigid video endoscope at 160[Formula: see text]lp/mm is greater than 0.1 while the root mean square (RMS) radii of the OCT beam in the center and edge of the FOV are 14.948[Formula: see text][Formula: see text]m and 73.609[Formula: see text][Formula: see text]m, respectively. The resolutions of both OCT and video endoscope meet the requirement of clinical application. In addition, all the components of the system are spherical, therefore the system can be of low cost and easy to assemble.

scholarly journals Manufacture of Contact Lens of Nanoparticle-Doped Polymer Complemented with ZEMAX

Nanomaterials ◽  
2020 ◽  
Vol 10 (10) ◽  
pp. 2028
Author(s):  
Lina M. Shaker ◽  
Ahmed A. Al-Amiery ◽  
Abdul Amir H. Kadhum ◽  
Mohd S. Takriff
Keyword(s):  
Contact Lenses ◽  
Titanium Dioxide Nanoparticles ◽  
Optical Design ◽  
Sol Gel ◽  
High Refractive Index ◽  
Light Transmittance ◽  
Great Promise ◽  
Modulation Transfer ◽  
Tio2 Nps ◽  
Molding Method

Many people suffer from myopia or hyperopia due to the refractive errors of the cornea all over the world. The use of high refractive index (RI), Abbe number (νd), and visible light transmittance (T%) polymeric contact lenses (CLs) holds great promise in vision error treatment as an alternative solution to the irreversible laser-assisted in situ keratomileusis (LASIK) surgery. Titanium dioxide nanoparticles (TiO2 NPs) have been suggested as a good candidate to rise the RI and maintain high transparency of a poly(methyl methacrylate) (PMMA)-TiO2 nanocomposite. This work includes a preparation of TiO2 NPs using the sol gel method as well as a synthesis of pure PMMA by free radical polarization and PMMA-TiO2 CLs using a cast molding method of 0.005 and 0.01 w/v concentrations and a study of their effect on the aberrated human eye. ZEMAX optical design software was used for eye modeling based on the Liou and Brennan eye model and then the pure and doped CLs were applied. Ocular performance was evaluated by modulation transfer function (MTF), spot diagram, and image simulation. The used criteria show that the best vision correction was obtained by the CL of higher doping content (p < 0.0001) and that the generated spherical and chromatic aberrations in the eye had been reduced.

Design of Projection Lithography Objective Lens with Sub-Ten Micrometer Line-Width and its MTF Experimental Measurements

2014 ◽  
Vol 901 ◽  
pp. 111-115
Author(s):  
Liang Lei ◽  
Xin Liu ◽  
Lang Lin Li ◽  
Jin Yun Zhou
Keyword(s):  
Wave Length ◽  
Optical Design ◽  
Field Of View ◽  
Objective Lens ◽  
Modulation Transfer ◽  
Projection Lithography ◽  
Fold Reduction ◽  
Result Show ◽  
Design Software ◽  
Imaging Performance

Double fold reduction projection lithography objective lens with bi-telecentric configuration, consists of 6 lenses and the number aperture , is designed based on the optical design software Zemax. It uses the 405nm laser diode (LD) as light source. The spatial resolving capacity approaches to 5um. In a field of view of , its wave-front aberration is less than a quarter of wave-length and the distortion ratio is not more than. The imaging performance, in particular, the accurate modulation transfer function (MTF) value of the projection objective lens being fabricated by experiments is determined in this paper. Through analyzing the noise disturbance law in MTF tests, the result show that the projection objective lens has sub ten micrometer resolving ability.

Layered polymer GRIN lenses and their benefits to optical designs

2015 ◽  
Vol 4 (5-6) ◽  
Author(s):  
Andrew Boyd ◽  
Michael Ponting ◽  
Howard Fein
Keyword(s):  
Optical Design ◽  
Field Of View ◽  
Gradient Index ◽  
Optical Performance ◽  
Design Study ◽  
Diffractive Lenses ◽  
Comparable Performance ◽  
Correction Potential

AbstractWe discuss the findings of a recent optical design study into layered polymeric gradient index lenses (known as L-GRIN). A range of GRIN singlet lenses were designed for various aperture and field-of-view configurations. Their optical performance was compared to polymer diffractive lenses and glass-cemented doublets (both spherical and aspheric) designed to the same specification. We find that diamond-turned polymer GRIN lenses offer comparable performance to achromatic doublets and polymer diffractive hybrid elements over a significant aperture and field-of-view range. We also find that the correction potential of GRIN solutions is substantially increased when the bulk GRIN Abbé value (

scholarly journals Optical Design of a Miniaturized Airborne Push-Broom Spectrometer

2020 ◽  
Vol 10 (7) ◽  
pp. 2627
Author(s):  
Yang Wang ◽  
Zhiyuan Gu ◽  
Xiangyue Meng ◽  
Lei Zhang ◽  
Yuegang Fu
Keyword(s):  
Unmanned Aerial Vehicle ◽  
Focal Length ◽  
Optical Design ◽  
Integrated System ◽  
Field Of View ◽  
Objective Lens ◽  
Wide Field ◽  
Modulation Transfer ◽  
Imaging Spectrometer ◽  
Aerial Vehicle

Combining the requirements of spectrometers for unmanned aerial vehicle platforms, a miniaturized airborne wide-angle push-broom imaging spectrometer with an Offner configuration is designed. The system comprises an objective lens and an Offner-type spectrometer with a spectral range of 400~1000 nm and a spectral resolution of 15 nm. The objective lens and Offner spectrometer are designed in isolation before integration. The front objective lens is an inverted telephoto with a focal length of 13 mm, a relative aperture of 1/4.5, and a field of view of 54°. The frequency of the convex grating in the Offner configuration is 102 LP/mm, and the dispersion width is 2.6 mm. The modulation transfer function of the integrated system is greater than 0.4 at the Nyquist frequency in all spectral bands. To estimate the volume and weight of the system, a preliminary optical–mechanical design scheme is given in this paper. The entire spectrometer has a volume of 130 × 80 × 120 mm and is less than 3 kg, which realizes the miniaturization design of the imaging spectrometer with a wide field of view for unmanned aerial vehicle platforms.

Non-Telecentric 2P microscopy for 3D random access mesoscale imaging at single cell resolution

2020 ◽  
Author(s):  
Filip Janiak ◽  
Philipp Bartel ◽  
Michael Bale ◽  
Takeshi Yoshimatsu ◽  
Emilia Komulainen ◽  
...  
Keyword(s):  
Single Cell ◽  
Neuronal Activity ◽  
Low Cost ◽  
Optical Design ◽  
Random Access ◽  
Field Of View ◽  
Three Dimensions ◽  
Image Brightness ◽  
Wide Range ◽  
Effective Excitation

Abstract In neuroscience, diffraction limited two-photon (2P) microscopy is a cornerstone technique that permits minimally invasive optical monitoring of neuronal activity. However, most conventional 2P microscopes impose significant constraints on the size of the imaging field-of-view and the specific shape of the effective excitation volume, thus limiting the scope of biological questions that can be addressed and the information obtainable. Here, employing a non-telecentric (nTC) optical design, we present an ultra-low-cost, easily implemented and flexible solution to address these limitations, offering a several-fold expanded three-dimensional field of view that also maintains single-cell resolution. We show that this implementation also allows for straight-forward tailoring of the point-spread-function, increases effective excitation power, and achievable image brightness. Moreover, rapid laser-focus control via an electrically tunable lens allows near-simultaneous imaging of remote regions separated in three dimensions and permits the bending of imaging planes to follow natural curvatures in biological structures. Crucially, our core design is readily implemented (and reversed) within a matter of hours, and compatible with a wide range of existing 2P customizations, making it highly suitable as a base platform for further development. We demonstrate the application of our system for imaging neuronal activity in a variety of examples in zebrafish, mice and fruit flies.

Compact, Wide-Angle Catadioptric Telescope Design for MWIR Imaging

2019 ◽  
Vol 8 (1) ◽  
pp. 33-48
Author(s):  
Sami D Alaruri
Keyword(s):  
Focal Length ◽  
Optical Design ◽  
Tolerance Analysis ◽  
Optical Path Difference ◽  
Path Difference ◽  
Field Of View ◽  
Modulation Transfer ◽  
Full Field ◽  
Field Curvature ◽  
Wavefront Error

In this work, the optical design of a compact diffraction-limited F/3.0 MWIR (3-5 µm) catadioptric telescope which consists of an aspheric primary mirror, a spherical secondary mirror, a ZnSe-ZnSe-Ge triplet lens and an air-spaced Si-Ge-Si corrector triplet lens placed before the focus is given. The calculated effective focal length, full field of view (FFOV) and angular magnification values for the designed telescope are 600 mm, 2.6° and -9.2, respectively. Zemax® calculations for the telescope MTF (modulation transfer function), PSF (point spread function), RMS (root-mean-square) wavefront error (WFE), optical path difference (OPD), Seidel aberrations, encircled energy, distortion and field curvature are discussed. The telescope performance analysis indicates that the telescope can achieve diffraction-limited image quality performance within the 2.6° full field-of-view. Additionally, the designed telescope can resolve at 50% contrast spatial frequency equal to 18.5 cycles/mm (at the on-axis FOV). Finally, a detailed tolerance analysis for the telescope design employing Monte Carlo and sensitivity analysis simulation features in Zemax® is provided.

scholarly journals Optical Design with Narrow-Band Imaging for a Capsule Endoscope

2018 ◽  
Vol 2018 ◽  
pp. 1-11 ◽  
Author(s):  
Chih-Ta Yen ◽  
Zong-Wei Lai ◽  
Yu-Ting Lin ◽  
Hsu-Chih Cheng
Keyword(s):  
Narrow Band ◽  
Narrow Band Imaging ◽  
Optical Design ◽  
Image Sensor ◽  
Field Of View ◽  
Lens Design ◽  
Capsule Endoscope ◽  
Pixel Size ◽  
Modulation Transfer ◽  
Intestinal Lesions

The study proposes narrow-band imaging (NBI) lens design of 415 nm and 540 nm of a capsule endoscope (CE). The researches show that in terms of the rate of accuracy in detecting and screening neoplastic and nonneoplastic intestinal lesions, the NBI system outperformed that of traditional endoscopes and rivaled that of chromoendoscopes. In the proposed NBI CE optical system, the simulation result shows the field of view (FOV) was 109.8°; the modulation transfer function (MTF) could achieve 12.5% at 285 lp/mm and 34.1% at 144 lp/mm. The relative illumination reaches more than 60%, and the system total length was less than 4 mm. Finally, this design provides high-quality images for a 300-megapixel 1/4″ CMOS image sensor with a pixel size of 1.75 μm.

scholarly journals Diagnostic Capabilities of a Smartphone- Based Low-Cost Microscope

2020 ◽  
Vol 6 (3) ◽  
pp. 522-525
Author(s):  
Dorina Hasselbeck ◽  
Max B. Schäfer ◽  
Kent W. Stewart ◽  
Peter P. Pott
Keyword(s):  
Low Cost ◽  
Field Of View ◽  
Parasitic Diseases ◽  
Optical Parameters ◽  
Trade Off ◽  
Resource Limited ◽  
Wide Range ◽  
Diagnostic Applications ◽  
Diagnostic Capabilities

AbstractMicroscopy enables fast and effective diagnostics. However, in resource-limited regions microscopy is not accessible to everyone. Smartphone-based low-cost microscopes could be a powerful tool for diagnostic and educational purposes. In this paper, the imaging quality of a smartphone-based microscope with four different optical parameters is presented and a systematic overview of the resulting diagnostic applications is given. With the chosen configuration, aiming for a reasonable trade-off, an average resolution of 1.23 μm and a field of view of 1.12 mm2 was achieved. This enables a wide range of diagnostic applications such as the diagnosis of Malaria and other parasitic diseases.

scholarly journals Optical Design of the Goaly3 Multi-Mirror Telescope System with a Wide Field of View

2021 ◽  
Vol 11 (3) ◽  
pp. 1200
Author(s):  
Junliu Fan ◽  
Quanying Wu ◽  
Baohua Chen ◽  
Lin Liu ◽  
Lei Chen
Keyword(s):  
Fill Factor ◽  
Optical Design ◽  
Tolerance Analysis ◽  
Field Of View ◽  
Wide Field ◽  
Aspheric Surfaces ◽  
The Monte Carlo Method ◽  
Wide Field Of View ◽  
Mirror Telescope ◽  
Telescope System

A Golay3 multi-mirror telescope (MMT) system is designed in this paper. The fill factor of the Golay3 MMT is derived from the angular resolution of the telescope. An initial configuration is established according to the paraxial optical theory. A three-element aspheric corrector group is designed and placed in the converging light cone to enlarge the field of view (FOV) of the Golay3 MMT. The tolerance analysis for each surface of the Golay3 MMT is conducted using the Monte Carlo method. The design results show the FOV of the Golay3 MMT system can be increased to 1.5° with the insertion of a three-element aspheric corrector group. The results of the tolerance analysis indicate that most tolerances are loose, while some decenter tolerances relating with the aspheric surfaces are relatively tight, but still within an acceptable range.

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