Protein Adsorption on Self-Assembled Monolayers Induced by Surface Water Molecule

2007 ◽  
Vol 46 (9B) ◽  
pp. 6303-6308 ◽  
Author(s):  
Yuzo Kanari ◽  
Yusuke Shoji ◽  
Hirotaka Ode ◽  
Takeo Miyake ◽  
Takashi Tanii ◽  
...  
Langmuir ◽  
1997 ◽  
Vol 13 (13) ◽  
pp. 3404-3413 ◽  
Author(s):  
Caren D. Tidwell ◽  
Sylvie I. Ertel ◽  
Buddy D. Ratner ◽  
Barbara J. Tarasevich ◽  
Sundar Atre ◽  
...  

2013 ◽  
Vol 2 (10) ◽  
pp. 1377-1387 ◽  
Author(s):  
Zheng Li ◽  
Alexander Köwitsch ◽  
Guoying Zhou ◽  
Thomas Groth ◽  
Bodo Fuhrmann ◽  
...  

2009 ◽  
Author(s):  
B. Szefczyk ◽  
M. N. D. S. Cordeiro ◽  
J. A. N. F. Gomes ◽  
Joaquín Marro ◽  
Pedro L. Garrido ◽  
...  

Langmuir ◽  
1997 ◽  
Vol 13 (7) ◽  
pp. 1881-1883 ◽  
Author(s):  
Stanislaw Petrash ◽  
Nina B. Sheller ◽  
William Dando ◽  
Mark D. Foster

2001 ◽  
Vol 12 (6) ◽  
pp. 581-597 ◽  
Author(s):  
Johan Benesch ◽  
Sofia Svedhem ◽  
Stefan C. T. Svensson ◽  
Ramu¯nas Valiokas ◽  
Bo Liedberg ◽  
...  

1991 ◽  
Vol 237 ◽  
Author(s):  
Kevin L. Prime ◽  
George M. Whttesides

ABSTRACTSelf-assembled monolayers (SAMs) of functionalized alkanethiolates on gold are a well-characterized system for studying the interfacial properties of organic materials. We have used SAMs as models for the surfaces of organic polymers and used mem to study the adsorption of proteins onto organic materials. We have formed SAMs from mixtures of alkanethiols in which one alkanethiol is hydrophobic and the other is terminated by a short (2 ≤ n ≤ 17) oligomer of poly(ethylene oxide). These “mixed” SAMs effectively resist the adsorption of fibrinogen from moderately concentrated (1 mg/mL) solutions. Protein adsorption begins when < 5% of the accessible area of the surface consists of hydrophobic groups. These findings suggest that real protein-resistant monolayers must present an almost defect-free surface of oligo(ethylene oxide) groups in order to eliminate adsorption.


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