Correlation between computed tomography and autopsy in premature and full-term neonates that have suffered perinatal asphyxia.

Radiology ◽  
1980 ◽  
Vol 137 (1) ◽  
pp. 93-103 ◽  
Author(s):  
O Flodmark ◽  
L E Becker ◽  
D C Harwood-Nash ◽  
P M Fitzhardinge ◽  
C R Fitz ◽  
...  
2020 ◽  
Author(s):  
Didi Stanine Mefo Kue ◽  
Aude Sabine Nanfack ◽  
ANNE ESTHER NJOM NLEND

Abstract Introduction Respiratory distress (RD) is a common condition for admission of newborns in neonatal care unit (NCU), in both preterm and full-term neonates. Our objective was to describe the clinical features, causes and treatment of RD in full term neonates in a tertiary health center in Yaoundé, the Essos Hospital Centre (EHC). Patients and Method We conducted a cross sectional retrospective study. Full term neonates with RD at EHC from January 2017 to December 2018 were included, assuming clinical signs of RD prior to 48 hours following admission. Factors evaluated: incidence of RD, main etiologies, short term outcomes and risk factors for severity. Data were collected using a chart, then analyzed using software Stata Version 13.Results 186 full term neonates out of 2312 newborn babies admitted in NCU, met the inclusion criteria giving a prevalence rate of RD of 8%. Sex ratio of 2.15 was favoring males; median age at admission was 7.25 hours and 89.2 % were born at a median gestational age of 38 weeks. Clinical signs of RD were dominated by signs of respiratory control with a Silverman score above 4/10 in 64%. The most common etiologies were neonatal infection / pneumonia (45.9%), followed by transient tachypnea. Clinical management was performed using nasal cannula oxygen and antibiotics. Perinatal asphyxia, cyanosis and caesarian section were found to be associated with severe RD in this setting. Mortality rate was 10.4%.Conclusion RD in full term neonates is common in this setting, with neonatal infection as preeminent etiology; the mortality rate is high and the management still inappropriate.


2016 ◽  
Vol 3 (9) ◽  
pp. 697-704
Author(s):  
Dr Deepthi Ramu ◽  
◽  
Dr Prashanth Madapura.V ◽  
Dr Sarala Sabapathy ◽  
Dr Nidhi Rajendra ◽  
...  

2020 ◽  
pp. 088307382097527
Author(s):  
Ki Won Oh ◽  
Gina Lim ◽  
Kyung Yeon Lee

Our province recently experienced an outbreak of neonatal rotavirus-associated leukoencephalopathy. This study aimed to verify whether rotavirus-associated leukoencephalopathy constituted fifth-day fits, which prevailed in Europe and Australia between the 1970s and mid-1980s. Of 118 full-term neonates who were admitted between 2008 and 2017 due to seizures, those who fulfilled the following criteria for fifth-day fits were included: healthy full-term neonates prior to seizures; absence of perinatal asphyxia; seizure onset during 4-6 days of age; and no known cause of neonatal seizures. Overall, 54 patients (45.8%) met the criteria for fifth-day fits. Of them, 44 patients (81.5%) also had rotavirus-associated leukoencephalopathy. The mean annual incidence of fifth-day fits was 5.4 cases, which peaked in 2012-2013 (13 cases) and became zero in 2017. Fifth-day fits with rotavirus-associated leukoencephalopathy accounted for 37.2% of neonatal seizures, which peaked at 70.6% in 2012, and gradually reduced to zero in 2017. Concordance of clinical features between rotavirus-associated leukoencephalopathy and fifth-day fits and their epidemic-like features suggest that rotavirus-associated leukoencephalopathy is one of the main causes of fifth-day fits.


Radiology ◽  
1983 ◽  
Vol 149 (1) ◽  
pp. 111-116 ◽  
Author(s):  
M J Siegel ◽  
J Patel ◽  
M H Gado ◽  
G D Shackelford

2021 ◽  
Vol 8 (10) ◽  
pp. 1695
Author(s):  
Rajiv Prasad ◽  
Vibhuti Vaghela ◽  
Radhika Iyer ◽  
Siddharth Verma ◽  
Jigar Anadkat

Background: Birth asphyxia can lead to hypoxic damage to liver at cellular level which leads to release of liver enzymes in blood as well as altered liver function. This study aimed to study the alteration of hepatic function in birth asphyxia and correlate it with different stages of hypoxic ischemic encephalopathy (HIE).Method: A case control study was conducted at SMIMER Surat which involved 115 cases and 115 controls. Cases were full term neonates admitted in the NICU with an APGAR score of 6 or less at 1 minute of birth while controls were those neonates with an APGAR score of 7 or more. Blood samples were taken at 72 hours of life and liver function tests of the 2 groups were compared.Results: The difference in aspartate transferase (AST), alanine transferase (ALT), lactate dehydrogenase (LDH), alkaline phosphatase (ALP) levels of the cases and controls were statistically significant (p<0.05). However, difference in total protein and total bilirubin in between the 2 groups was statistically insignificant. The study also found that the difference in AST, ALT and LDH was statistically significant between HIE stage 1 and stage 2 (p<0.5), between HIE stage 1 and stage 3 (p<0.5) but insignificant between HIE stage 2 and stage 3 (p>0.5).Conclusions: The present study showed that the serum levels of hepatic enzymes were higher in full term neonates with perinatal asphyxia than full term neonates without perinatal asphyxia at the age of 72 hours. The enzyme levels showed an increasing trend with increasing severity of HIE.


2006 ◽  
Vol 28 (3) ◽  
pp. 339-344 ◽  
Author(s):  
Charlotte van Kesteren ◽  
Manon J. N. L. Benders ◽  
Floris Groenendaal ◽  
Frank van Bel ◽  
F. F. Tessa Ververs ◽  
...  

Neonatology ◽  
2018 ◽  
Vol 114 (3) ◽  
pp. 253-260 ◽  
Author(s):  
Ken Imai ◽  
Linda S. de Vries ◽  
Thomas Alderliesten ◽  
Nienke Wagenaar ◽  
Niek E. van der Aa ◽  
...  

Sign in / Sign up

Export Citation Format

Share Document