Recently, the increased use of antibiotics in the environment has been studied and one of them is amoxicillin. Amoxicillin (AMX) is a pharmaceutical product that can become waste due to the continuous use and released into the ecosystem even at low concentrations. The electro-oxidation process is one of the electrochemical methods used to destruct the existence of antibiotics because the process is relatively fast and inexpensive. Platinum electrode and platinum modified cobalt electrodes are used for amoxicillin electro-oxidation at the pH of 2 - 7. The range of this amoxicillin's pH was achieved by the pKa's values of the amoxicillin and measured using a UV/Vis spectrophotometer. Electron transfer during the amoxicillin electro-oxidation process with these electrodes is measured by linear sweep voltammetry. The results obtained during the electro-oxidation process showed that electron transfer of amoxicillin was 1, with a Nernstian factor of 0.0521 V/pH for platinum electrode and platinum modified cobalt electrodes, Pt/Co(OH)2 and Pt/Co respectively with values of 0.0506 V/pH and 0.0673 V/pH.
