Long-term vascular access in the rat: importance of asepsis

1981 ◽  
Vol 241 (4) ◽  
pp. H606-H612 ◽  
Author(s):  
M. B. Popp ◽  
M. F. Brennan
Keyword(s):  
Superior Vena ◽  
Experimental Studies ◽  
Vena Cava ◽  
Sham Operation ◽  
Fischer 344 Rats ◽  
Fischer 344 ◽  
Catheter Infection ◽  
Catheterization Technique ◽  
Vascular Catheters

Chronic indwelling vascular catheters have been used in the rat for many types of experimental studies. Most experiments have been of short duration with little attention to aseptic technique during catheter placement. In this study, rats subjected to a sterile superior vena cava (SVC) catheterization technique, a convential clean but nonsterile SVC catheterization technique, or sham operation were compared. Male Fischer 344 rats (wt 175-200 g) were catheterized or sham operated and then received food and water ad libitum for 25 days. At time of spontaneous death or being killed the SVC was examined grossly and microscopically for infection. Three of six nonsterile conventionally catheterized animals died, and five of these six animals had infected catheters. All sterilely catheterized and sham-operated rats lived 25 days, and none had catheter infection. Sterilely catheterized rats gained weight (1.9 g/day), were in positive nitrogen balance, and had organ weight and blood studies similar to sham-operated noncatheterized controls. Nonsterile catheterization resulted in catheter infection such that normal physiological studies would be uninterpretable.

Partial Anomalous Pulmonary Venous Connection: Forty-Six Years of Follow-Up

2021 ◽  
Vol 12 (1) ◽  
pp. 70-75
Author(s):  
Anne Kathrine M. Nielsen ◽  
Vibeke E. Hjortdal
Keyword(s):  
Superior Vena Cava ◽  
Superior Vena ◽  
Sinus Node ◽  
Vena Cava ◽  
Node Disease ◽  
Sinus Node Disease ◽  
Patch Technique ◽  
Anomalous Pulmonary Venous Connection

Background: Surgical repair of partial anomalous pulmonary venous connection (PAPVC) may disturb the electrical conduction in the atria. This study documents long-term outcomes, including the late occurrence of atrial tachyarrhythmia and bradyarrhythmia. Methods: This retrospective study covers all PAPVC operations at Aarhus University Hospital between 1970 and 2010. Outcome measures were arrhythmias, sinus node disease, pacemaker implantation, pathway stenosis (pulmonary vein(s), intra-atrial pathway, and/or superior vena cava), and mortality. Data were collected from databases, surgical protocols, and hospital records until May 2018. Results: A total of 83 patients were included with a postoperative follow-up period up to 46 years. Average age at follow-up was 43 ± 21 years. During follow-up, new-onset atrial fibrillation or atrial flutter appeared in four patients (5%). Sinus node disease was present in nine patients (11%). A permanent pacemaker was implanted in seven patients (8%) at an average of 12.7 years after surgery. Pulmonary venous and/or superior vena cava obstruction was seen in five patients (6%). Stenosis was most prevalent in the two-patch technique, and arrhythmia was most prevalent in the single-patch technique. Sixty-seven (81%) of 83 patients had neither bradyarrhythmias nor tachyarrhythmias or pacemaker need. Conclusions: This study contributes important long-term data concerning the course of patients who have undergone repair of PAPVC. It confirms that PAPVC can be operated with low postoperative morbidity. However, late-onset stenosis, bradyarrhythmias and tachyarrhythmias, and need for pacemaker call for continued follow-up.

The Different Impacts on the Long-Term Survival of Tunneled Internal Jugular Hemodialysis Catheters Based on Tip Position and Laterality

2017 ◽  
Vol 43 (4) ◽  
pp. 315-320 ◽  
Author(s):  
Vedran Premuzic ◽  
Drazen Perkov ◽  
Ranko Smiljanic ◽  
Bruna Brunetta Gavranic ◽  
Bojan Jelakovic
Keyword(s):  
Superior Vena ◽  
Vena Cava ◽  
The Body ◽  
Term Survival ◽  
Catheter Tip ◽  
Tip Position ◽  
The Impact

Background/Aims: The aim of this study was to examine the impact of different catheter tip positions on the life of the catheter, dysfunction, infection, and quality of hemodialysis and possible differences between the access site laterality in jugular-tunneled hemodialysis catheters. Methods: Catheters were evaluated for the following parameters: place of insertion, time of insertion, duration of use, and reason for removal. In all patients, the catheter tip position was checked using an X-ray. Results: The mean duration of implanted catheters with the tip placed in the cavo-atrial junction and right atrium was significantly longer. There were no differences in catheter functionality at follow-up or complications based on catheter laterality for each catheter tip position. Conclusion: According to our results, the localization of the catheter tip in superior vena cava still remains the least preferable method. Our results showed that the main factor responsible for better catheter functionality was not laterality but the depth to which the catheter tip is inserted into the body.

scholarly journals Long-term follow-up after prosthetic replacement of the superior vena cava combined with resection of mediastinal-pulmonary malignant tumors

1991 ◽  
Vol 102 (2) ◽  
pp. 259-265 ◽  
Author(s):  
Philippe G. Dartevelle ◽  
Alain R. Chapelier ◽  
Ugo Pastorino ◽  
Pierre Corbi ◽  
Bernard Lenot ◽  
...  
Keyword(s):  
Superior Vena Cava ◽  
Malignant Tumors ◽  
Superior Vena ◽  
Vena Cava ◽  
Prosthetic Replacement ◽  
Long Term Follow Up

scholarly journals Chylothorax and Chylopericardium: A Complication of Long-Term Central Venous Catheter Use

2019 ◽  
Vol 2019 ◽  
pp. 1-5
Author(s):  
James Livesay ◽  
Isaac Biney ◽  
J. Francis Turner
Keyword(s):  
Superior Vena Cava ◽  
Superior Vena ◽  
Disease Patient ◽  
Vena Cava ◽  
Venous Catheter ◽  
Central Venous ◽  
Vena Cava Syndrome ◽  
Stage Renal Disease ◽  
End Stage

The development of chylothorax and chylopericardium is an uncommon complication of the long-term use of central venous catheters. We describe a unique case of an end stage renal disease patient on hemodialysis with a left jugular tunneled catheter who developed superior vena cava syndrome. Our patient presented with both a large pleural and pericardial effusion that despite drainage continued to reaccumulate. Further imaging with CT scan of the thorax revealed stenosis of the superior vena cava leading to recurrent chylothorax and chylopericardium.

The effect of a long term (6 months) treatment with (−)deprenyl on antioxidant enzyme activities in selective brain regions in old female fischer 344 rats

1994 ◽  
Vol 47 (8) ◽  
pp. 1333-1338 ◽  
Author(s):  
Maria Cristina Carrillo ◽  
Kenichi Kitani ◽  
Setsuko Kanai ◽  
Yuko Sato ◽  
Kyoko Miyasaka ◽  
...  
Keyword(s):  
Antioxidant Enzyme ◽  
Enzyme Activities ◽  
Brain Regions ◽  
Antioxidant Enzyme Activities ◽  
Fischer 344 Rats ◽  
Fischer 344

Long-Term Outcome of Catheter Ablation in Patients with Atrial Fibrillation Originating from the Superior Vena Cava

2012 ◽  
Vol 23 (9) ◽  
pp. 955-961 ◽  
Author(s):  
HUNG-YU CHANG ◽  
LI-WEI LO ◽  
YENN-JIANG LIN ◽  
SHIH-LIN CHANG ◽  
YU-FENG HU ◽  
...  
Keyword(s):  
Atrial Fibrillation ◽  
Catheter Ablation ◽  
Superior Vena Cava ◽  
Superior Vena ◽  
Vena Cava ◽  
Term Outcome ◽  
Long Term Outcome
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