Differences in the dynamic cerebrovascular response between stepwise up tilt and down tilt in humans

2001 ◽  
Vol 281 (2) ◽  
pp. H774-H783 ◽  
Author(s):  
Jiro Sato ◽  
Masatoshi Tachibana ◽  
Tsutomu Numata ◽  
Takashi Nishino ◽  
Akiyoshi Konno
Keyword(s):  
Doppler Ultrasonography ◽  
Cerebral Blood Flow Velocity ◽  
Cardiovascular Responses ◽  
Second Order ◽  
Order Model ◽  
Healthy Humans ◽  
Arterial Blood ◽  
Critical Closing Pressure ◽  
Closing Pressure ◽  
Second Order Model

We studied dynamic cerebrovascular responses in eight healthy humans during repetitive stepwise upward tilt (SUT) and stepwise downward tilt (SDT) maneuvers between supine and 70° standing at intervals of 60 s. Mean cerebral blood flow velocity (FVMCA) was measured at the middle cerebral artery (MCA) with transcranial Doppler ultrasonography. Mean arterial blood pressure (ABP) was measured via the radial artery and adjusted at the level of the MCA (ABPMCA). Cerebral critical closing pressure (PCC) was estimated from the systolic-diastolic relationship between FVMCA and ABPMCA. ABPMCA minus PCC was considered the cerebral perfusion pressure (CPP). The tilt maneuvers produced stepwise changes in both CPP and FVMCA. The FVMCA response to SUT was well characterized by a linear second-order model. However, that to SDT presented a biphasic behavior that was described significantly better ( P < 0.05) by the addition of a slowly responding component to the second-order model. This difference may reflect both different cardiovascular responses to SUT or SDT and different cerebrovascular autoregulatory behaviors in response to decreases or increases in CPP.

scholarly journals Frequency Dependence of Cerebrovascular Impedance in Preterm Neonates: A Different View on Critical Closing Pressure

1997 ◽  
Vol 17 (10) ◽  
pp. 1127-1131 ◽  
Author(s):  
Erik Michel ◽  
Stefanie Hillebrand ◽  
Johanna vonTwickel ◽  
Boris Zernikow ◽  
Gerd Jorch
Keyword(s):  
Blood Pressure ◽  
Frequency Response ◽  
Cerebral Blood Flow Velocity ◽  
Preterm Neonates ◽  
Pass Filter ◽  
Arterial Blood ◽  
Critical Closing Pressure ◽  
Cerebrovascular System ◽  
Closing Pressure ◽  
Zero Frequency

The nonproportional relationship between instantaneous arterial blood pressure (BP) and cerebral blood flow velocity (CBFv) is well explained by the concept of critical closing pressure (CCP). We aimed to determine the frequency response of the neonatal cerebrovascular system, and to establish the exact mathematical relationship between cerebrovascular impedance and CCP under physiologic conditions. In 10 preterm neonates (gestational age, 25–32 weeks; birth weight, 685–1,730 g; age 1–7 days) we Doppler-traced CBFv of the internal carotid artery. Blood pressure was traced simultaneously. Critical closing pressure was graphically determined. Cerebrovascular impedance was calculated as the square root of the ratio of the corresponding peaks in the power spectra of BP and CBFv at zero frequency, and at heart rate (H) and harmonics (xH). Uniformly, the impedance between H and 3H (2 to 6 Hz) was reduced about fivefold, compared with the impedance at zero frequency. The cerebrovascular system behaves like a high-pass filter, leading to a reduction of the DC (direct current) component of CBFv (analogous to current) relative to that of the driving force BP (analogous to voltage). The frequency response of cerebrovascular impedance reflects the ratio of CCP and DC BP. A mathematical derivation of this relationship is given matching the observed results. Thus, both the CCP and the impedance approach are valid.

Adsorption Kinetics of Pb2+ Ions Using Chitosan Nanoparticles

2013 ◽  
Vol 367 ◽  
pp. 45-49
Author(s):  
Ying Hong ◽  
Ze Hui Zhong ◽  
You Shi Liu
Keyword(s):  
Adsorption Kinetics ◽  
Chitosan Nanoparticles ◽  
Second Order ◽  
Isotherm Model ◽  
Order Model ◽  
Adsorption Characteristics ◽  
Pseudo Second Order ◽  
Kinetics Of ◽  
Second Order Model

Chitosan nanoparticles were prepared by crosslinkingusing TPP. SEM showed that chitosan nanoparticles were successfully obtained.The adsorption characteristics of chitosan nanoparticles were evaluated. Theresults demonstrated that chitosan nanoparticles were suitable for adsorbent toremoval Pb2+. The parameters for the adsorption of Pb2+by chitosan nanoparticles were also determined. It was shown that chitosannanoparticles were fit for Langmuir’s isotherm model and that the adsorptionkinetics of Pb2+ described by the pseudo-second-order model could bebest.

Polyaniline/ZnO nanocomposites for the removal of methyl orange dye from waste water

2018 ◽  
Vol 32 (19) ◽  
pp. 1840085 ◽  
Author(s):  
Neha V. Nerkar ◽  
Subhash B. Kondawar ◽  
Snehal Kargirwar Brahme ◽  
Yun Hae Kim
Keyword(s):  
Waste Water ◽  
Methyl Orange ◽  
Adsorption Mechanism ◽  
Second Order ◽  
Pure Pani ◽  
Time Interval ◽  
Order Model ◽  
Vis Spectroscopy ◽  
Pseudo Second Order ◽  
Second Order Model

In this paper, we report the safe removal of methyl orange (MO) dye from aqueous solution using chemical interaction of dye molecule with polyaniline/zinc oxide (PANI/ZnO) nanocomposite. PANI/ZnO nanocomposite has been prepared by in situ polymerization. PANI/ZnO nanocomposite was found to be the best promising candidate for adsorption of dyes due to more porosities compared to that of pure PANI. In the present investigation, PANI/ZnO nanocomposite was mixed in a solution of MO dye and used for adsorption process. Color removal was studied using UV-Vis spectroscopy and the spectra were recorded for specific time interval and validation of kinetic model has been applied. Absorbance of PANI/ZnO nanocomposite was found to be increased as compared to that of pure ZnO nanoparticles and pure PANI due to synergistic effect. Comparatively, the removal of dye was also found to be more by using PANI/ZnO nanocomposites. In order to evaluate kinetic mechanism the pseudo-first-order model, pseudo-second-order model and intraparticle diffusion models were verified by the linear equation analysis. Adsorption mechanism of pseudo-second-order model was systematically explained for removal of dye using PANI/ZnO nanocomposite. The results clearly demonstrated that the adsorption mechanism gives very novel and green method of removal of hazardous dyes from waste water.

scholarly journals Validating a second-order model for oil and gas projects’ investment climate scale

2017 ◽  
Vol 11 (1) ◽  
pp. 65-79 ◽  
Author(s):  
Abdulsalam Mas’ud ◽  
Nor Aziah Abd Manaf ◽  
Natrah Saad
Keyword(s):  
Goodness Of Fit ◽  
Oil And Gas ◽  
Second Order ◽  
Fit Indices ◽  
Investment Climate ◽  
Order Model ◽  
Content Type ◽  
Latent Construct ◽  
Climate Scale ◽  
Second Order Model

Purpose The investment climate is one of the key factors considered by foreign investors while deciding their investment destination. This paper aims to attempt at validating the second-order model of oil and gas projects’ investment climate. Examination of the relationship between the dimensions of oil and gas projects’ investment climate; strategy, participants/operating environment and risk/return; and the overall latent construct was conducted. The study also evaluates the goodness of fit of the second-order model using relevant fit indices. Design/methodology/approach Oil and gas experts in Malaysian marginal oil fields subsector were deployed, through whom responses were collected that formed the data set used in the analysis. Then, the data were used for confirmatory factor analysis, evaluation of the second-order model through path analysis and for model fit evaluation. Findings The finding revealed that the second-order model of oil and gas projects’ investment climate is valid and reliable. It also revealed that all the three dimensions, strategy, participants/operating environment and risk/return, have significant effects on the formation of the oil and gas projects’ investment climate. Finally, the goodness of fit of the second-order model satisfied the relevant fit indices. Research limitations/implications The findings present valuable insights to policymakers on the extent of the influence each of the dimensions has on the overall latent construct. The validity and reliability analysis suggests the measurements of the second-order model of oil and gas projects’ investment climate construct, and its dimensions are valid, reliable and fit for future empirical research. Thus, it calls for replication in other oil and gas settings. Originality/value The findings from the results of this study are pioneering. Extant literature falls short in attempting the validation of the second-order oil and gas projects’ investment climate scale, as well as relating each of the dimensions with the overall latent construct.

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