Antinuclear Antibody-Positive Ticlopidine-Induced Hepatitis
1996 ◽
Vol 10
(4)
◽
pp. 231-232
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Keyword(s):
Ticlopidine hydrochloride has been shown to reduce the risk of first or recurrent stroke in patients who have experienced a transient ischemic attack, reversible ischemic neurological deficit, recurrent stroke or first stroke. Severe liver dysfunction is a contraindication for its use. Increase in liver enzymes has been reported with use of this drug, but jaundice is rare. A case of severe ticlopidine-induced hepatitis that was associated with a marked increase in antinuclear antibody (ANA) levels is reported. Physicians prescribing ticlopidine hydrochloride should be aware that a potentially severe acute hepatitis associated with ANA positivity can occur. The drug should be discontinued if signs of liver dysfunction occur.
Keyword(s):
2017 ◽
Vol 12
(3)
◽
pp. 302-320
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Keyword(s):
2010 ◽
Vol 52
(2)
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pp. e105-e107
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2012 ◽
Keyword(s):
2015 ◽
Vol 47
(5)
◽
pp. 256-262
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Keyword(s):