scholarly journals Steroids and/or Cytotoxic Agents Should Be Used Early in the Management of Patients with IPF -- The Con Argument

2004 ◽  
Vol 11 (3) ◽  
pp. 212-213 ◽  
Author(s):  
Stephen K Field

The recently published American Thoracic Society/European Respiratory Society statement distinguishes idiopathic pulmonary fibrosis (IPF), also known as usual interstitial pneumonia (UIP), from the other idiopathic interstitial pneumonias (IIPs) (1). Although the current classification of IIPs is different from the one developed by Liebow and Carrington (2) in the 1960s, the description of UIP has not changed, and it is still recognized as having distinctive clinical and pathological features that distinguish it from the other IIPs. IPF responds differently to systemic corticosteroid (steroid) therapy and has a different prognosis than the other IIPs, such as nonspecific interstitial pneumonitis, which previously were felt to be variants of the same condition (1,3,4). Despite therapy, most patients with IPF experience a progressive decline in pulmonary function, leading to respiratory failure and death, unless they undergo lung transplantation.

1967 ◽  
Vol 113 (500) ◽  
pp. 779-780 ◽  
Author(s):  
Mark D. Altschule

One current classification of depression divides the syndrome into psychotic and non-psychotic varieties. It is interesting that a similar classification developed over a thousand years ago out of some words of St. Paul. In his Second Epistle to the Corinthians, Ch. 7, v. 10, Paul wrote: “For godly sorrow worketh repentance to salvation not to be repented of, but the sorrow of the world worketh death.” The word sorrow used in English translations of the Bible stood for the tristitia of Latin versions (Greek λνπη); connoting sadness, sorrow, despondency, depression. Paul's distinction between the two kinds of tristitia, the one “from God” and the other “of the world”, led mediaeval theologians to enlarge on differences between the two kinds of depression.


Author(s):  
I. Kukhtevich

Functional autonomic disorders occupy a significant part in the practice of neurologists and professionals of other specialties as well. However, there is no generally accepted classification of such disorders. In this paper the authors tried to show that functional autonomic pathology corresponds to the concept of somatoform disorders combining syndromes manifested by visceral, borderline psychopathological, neurological symptoms that do not have an organic basis. The relevance of the problem of somatoform disorders is that on the one hand many health professionals are not familiar enough with manifestations of borderline neuropsychiatric disorders, often forming functional autonomic disorders, and on the other hand they overestimate somatoform symptoms that are similar to somatic diseases.


Author(s):  
Valerii P. Trykov ◽  

The article examines the conceptual foundations and scientific, sociocultural and philosophical prerequisites of imagology, the field of interdisciplinary research in humanitaristics, the subject of which is the image of the “Other” (foreign country, people, culture, etc.). It is shown that the imagology appeared as a response to the crisis of comparatives of the mid-20th century, with a special role in the formation of its methodology played by the German comparatist scientist H. Dyserinck and his Aachen School. The article analyzes the influence on the formation of the imagology of post-structuralist and constructivist ideological-thematic complex (auto-reference of language, discursive history, construction of social reality, etc.), linguistic and cultural turn in the West in the 1960s. Shown is that, extrapolated to national issues, this set of ideas and approaches has led to a transition from the essentialist concept of the nation to the concept of a nation as an “imaginary community” or an intellectual construct. A fundamental difference in approaches to the study of an image of the “Other” in traditional comparativism and imagology, which arises from a different understanding of the nation, has been distinguished. It is concluded that the imagology studies the image of the “Other” primarily in its manipulative, socio-ideological function, i.e., as an important tool for the formation and transformation of national and cultural identity. The article identifies ideological, socio-political factors that prepared the birth of the imagology and ensured its development in western Humanities (fear of possible recurrences of extreme nationalism and fascism in post-war Europe, the EU project, which set the task of forming a pan-European identity). It is concluded that the imagology, on the one hand, has actualized an important field of scientific research — the study of the image of the “Other”, but, on the other hand, in the broader cultural and historical perspective, marked a departure not only from the traditions of comparativism and historical poetics, but also from the humanist tradition of the European culture, becoming part of a manipulative dominant strategy in the West. To the culture of “incorporation” into a “foreign word” in order to understand it, preserve it and to ensure a genuine dialogue of cultures, the imagology has contrasted the social engineering and the technology of active “designing” a new identity.


Author(s):  
Valerii Dmitrienko ◽  
Sergey Leonov ◽  
Mykola Mezentsev

The idea of ​​Belknap's four-valued logic is that modern computers should function normally not only with the true values ​​of the input information, but also under the conditions of inconsistency and incompleteness of true failures. Belknap's logic introduces four true values: T (true - true), F (false - false), N (none - nobody, nothing, none), B (both - the two, not only the one but also the other).  For ease of work with these true values, the following designations are introduced: (1, 0, n, b). Belknap's logic can be used to obtain estimates of proximity measures for discrete objects, for which the functions Jaccard and Needhem, Russel and Rao, Sokal and Michener, Hamming, etc. are used. In this case, it becomes possible to assess the proximity, recognition and classification of objects in conditions of uncertainty when the true values ​​are taken from the set (1, 0, n, b). Based on the architecture of the Hamming neural network, neural networks have been developed that allow calculating the distances between objects described using true values ​​(1, 0, n, b). Keywords: four-valued Belknap logic, Belknap computer, proximity assessment, recognition and classification, proximity function, neural network.


Author(s):  
Oksana Chaika ◽  

The paper research is work in progress and makes part of a publication set devoted the study of the English monomials and polynomials in the professional domain of audit and accounting, on the one hand. On the other, the research can be treated as a standalone piece for the study into the nature of verbal monomials as set term clusters in English for Audit and Accounting. The scope of research arrives at the following objectives. One objective is to give an overview of the term ‘monomial’ in English for Audit and Accounting, or English for A&A, which leads to understanding of the verbal monomial in English for A&A, correspondingly. The other objective refers to the classification introduced earlier as attributable to the analysis of the structure of the mentioned monomials and polynomials in English for A&A from a morphological perspective of the head term in a monomial, i.e. nounal, verbal, adjectival and adverbial. The said classification in this work associates with verbal monomials in English for A&A only, and provides a relevant sub-classification of the relevant verbal monomials through the lens of their functional properties and roles in a sentence, under the professional language framework. The results and discussion section presents five distinct groups of verbal monomials in English for Audit and Accounting, each corresponding to a specific syntactical role and functional property in a sentence. A variety of the examples helps see and identify the type of the English verbal monomial in the area of audit and accounting.


Author(s):  
Edward G. Goetz

This chapter describes the tension between integration and community development from the 1940s through the end of the 1960s. It describes the conflict within the African-American community between efforts to achieve integration on the one hand and building power and capacity within the community on the other. It describes the emergence and evolution of the fair housing movement in the U.S. Finally, the ways in which this conflict played out during the civil rights and Black Power eras is highlighted.


2020 ◽  
Vol 5 (1) ◽  
pp. 17-38 ◽  
Author(s):  
K. Seto ◽  
S. Van Den Wyngaert ◽  
Y. Degawa ◽  
M. Kagami

During the last decade, the classification system of chytrids has dramatically changed based on zoospore ultrastructure and molecular phylogeny. In contrast to well-studied saprotrophic chytrids, most parasitic chytrids have thus far been only morphologically described by light microscopy, hence they hold great potential for filling some of the existing gaps in the current classification of chytrids. The genus Zygorhizidium is characterized by an operculate zoosporangium and a resting spore formed as a result of sexual reproduction in which a male thallus and female thallus fuse via a conjugation tube. All described species of Zygorhizidium are parasites of algae and their taxonomic positions remain to be resolved. Here, we examined morphology, zoospore ultrastructure, host specificity, and molecular phylogeny of seven cultures of Zygorhizidium spp. Based on thallus morphology and host specificity, one culture was identified as Z. willei parasitic on zygnematophycean green algae, whereas the others were identified as parasites of diatoms, Z. asterionellae on Asterionella, Z. melosirae on Aulacoseira, and Z. planktonicum on Ulnaria (formerly Synedra). According to phylogenetic analysis, Zygorhizidium was separated into two distinct order-level novel lineages; one lineage was composed singly of Z. willei, which is the type species of the genus, and the other included the three species of diatom parasites. Zoospore ultrastructural observation revealed that the two lineages can be distinguished from each other and both possess unique characters among the known orders within the Chytridiomycetes. Based on these results, we accommodate the three diatom parasites, Z. asterionellae, Z. melosirae, and Z. planktonicum in the distinct genus Zygophlyctis, and propose two new orders: Zygorhizidiales and Zygophlyctidales.


1973 ◽  
Vol 14 (2) ◽  
pp. 257-274 ◽  
Author(s):  
M. Tamarkin

From a close analysis of African activities and actions in the Kenyan town of Nakuru from the 19205 to the 1960s, it is argued that living in towns tended to consolidate the identities of tribal groups and to exacerbate their differences. Contrasts between the urban responses of the Kikuyu, on the one hand, and the Western Kenyan tribes, the Luo and the Abaluhya, on the other, are analysed, and are related to differences in the tribal structures and in the political, economic and social changes that were taking place in their rural areas. By the early 1960s, the stage was set for open political competition between tribal groups.


2017 ◽  
Vol 47 (3) ◽  
pp. 429-448
Author(s):  
Anne O’Byrne

Abstract Taxonomy is our response to the proliferating variety of the natural world on the one hand, and the principle of unrelieved universality on the other. From Aristotle, through Porphyry to Linneaus, Kant and others, thinkers have struggled to develop taxonomies that could order what we know and also what we do not yet know, and this essay is a reflection on the existential desire that propels this effort. Porphyry’s tree of logic is an exhaustive account of the things we can say about the sort of beings we are; Linneaus’s system of nature reaches completion in the classification of humans; Kant discovers a way to have natural and logical forms coincide in the thought of natural purpose and purposiveness. The stakes are high. When we order the world, we order ourselves: when we enter the taxonomy, it enters us and confronts us with our judgments of kind, race and kin.


Author(s):  
Paul Schor

This chapter discusses changes in racial categorization in the early twentieth century with respect to the US census. Whenever there was a question of the racial classification of new populations, whether in the continental United States or in the territories acquired since 1867, the census always relied on the principles and techniques developed since 1850 to distinguish blacks from whites. Chief among these was the principle of hypodescent, in more or less rigid forms. However, the early twentieth century saw change occurring in two directions: on the one hand, the racialization of a growing number of non-European immigrants and their descendants; on the other, the weakening of the distinctions between the descendants of European immigrants. The remainder of the chapter details the disappearance of the “mulatto” category and the introduction and forcible elimination of the “Mexican” category.


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