scholarly journals High Rate of Severe Fetal Outcomes Associated with Maternal Parvovirus B19 Infection in Pregnancy

2008 ◽  
Vol 2008 ◽  
pp. 1-4 ◽  
Author(s):  
Richard H. Beigi ◽  
Harold C. Wiesenfeld ◽  
Daniel V. Landers ◽  
Hyagriv N. Simhan
Keyword(s):  
Parvovirus B19 ◽  
Case Series ◽  
Fetal Loss ◽  
High Rate ◽  
Retrospective Case ◽  
Fetal Outcomes ◽  
Maternal Characteristics ◽  
Parvovirus B19 Infection ◽  
Trend Variation ◽  
In Pregnancy

Objective. To augment the understanding of parvovirus B19 infection in pregnancy with respect to maternal characteristics and their corresponding fetal outcomes.Study Design. Retrospective case-series of all women referred to Magee-Women_s Hospital with serologically-documented parvovirus B19 infection during pregnancy from 1998–2001.Results. All 25 cases that are available for analysis occurred from January through June. The frequency of cases varied substantially from year to year, with 14 cases in 1998, 0 cases in 1999 and 2000, and 11 cases in 2001. In contrast to previous reports, the minority of women [4/25(16%)] experienced symptoms attributable to parvovirus B-19 infection although 3 of 25 (12%) fetuses developed hydrops fetalis and 4/25 (16%) suffered an intrauterine of fetal death.Conclusions. These findings suggest that parvovirus B19 infection in pregnancy follows seasonal and annual trend variation, may produce a lower frequency of maternal symptoms and a higher fetal loss rate than previously reported.Synopsis. Maternal parvovirus B19 infection follows seasonal and annual variation is often asymptomatic and may have higher fetal loss rates than previously reported. Continued surveillance is warranted.

PARVOVIRUS B19 INFECTION IN PREGNANCY

2005 ◽  
Vol 16 (2) ◽  
pp. 123-150 ◽  
Author(s):  
BERNARD J COHEN ◽  
SAILESH KUMAR
Keyword(s):  
Parvovirus B19 ◽  
Fetal Loss ◽  
Laboratory Diagnosis ◽  
Test Results ◽  
Highly Pathogenic ◽  
Congenital Rubella ◽  
Parvovirus B19 Infection ◽  
Asymptomatic Infections ◽  
Species Specific ◽  
In Pregnancy

Parvoviruses are widespread in nature, with a diversity of virus types affecting many animal species, usually in a species-specific manner. Some members of the parvovirus family give rise to asymptomatic infections but others are highly pathogenic, causing disease not only in adults but also in the young, the newborn and in the fetus. Parvoviruses of animals have for long been regarded as agents of reproductive failure and parvovirus B19 was recognised as a cause of fetal loss in humans in the 1980s. Moreover, following the control of congenital rubella by pre-pubertal and child vaccination, parvovirus B19 infection has emerged as probably the leading cause of viral embryopathy. This review will focus on the laboratory diagnosis of parvovirus B19 infection following exposure in pregnancy. The indications for testing maternal and fetal samples and the interpretation of test results will be discussed and a section is included on clinical management of the infection in pregnancy. The obstetric outcome in pregnant women who seroconvert will be reviewed.

Fetal morbidity and mortality after acute human parvovirus B19 infection in pregnancy: prospective evaluation of 1018 cases

2004 ◽  
Vol 24 (7) ◽  
pp. 513-518 ◽  
Author(s):  
Martin Enders ◽  
Andrea Weidner ◽  
Iris Zoellner ◽  
Karen Searle ◽  
Gisela Enders
Keyword(s):  
Parvovirus B19 ◽  
Morbidity And Mortality ◽  
Human Parvovirus B19 ◽  
Prospective Evaluation ◽  
Parvovirus B19 Infection ◽  
In Pregnancy

Audit of insulin detemir in pregnancy: a retrospective case series

2012 ◽  
Vol 29 (7) ◽  
pp. 958-959 ◽  
Author(s):  
V. V. Shenoy ◽  
S. J. Cook ◽  
A. F. Parry ◽  
H. D. McIntyre
Keyword(s):  
Insulin Detemir ◽  
Case Series ◽  
Retrospective Case ◽  
Retrospective Case Series ◽  
In Pregnancy

Diagnosis, management and possibilities to prevent parvovirus B19 infection in pregnancy

2011 ◽  
Vol 6 (12) ◽  
pp. 1435-1450 ◽  
Author(s):  
Annelie Plentz ◽  
Susanne Modrow
Keyword(s):  
Parvovirus B19 ◽  
Parvovirus B19 Infection ◽  
In Pregnancy

Parvovirus B19 infection in pregnancy — awareness and opportunities

2017 ◽  
Vol 27 ◽  
pp. 8-14 ◽  
Author(s):  
Francesca Bonvicini ◽  
Gloria Bua ◽  
Giorgio Gallinella
Keyword(s):  
Parvovirus B19 ◽  
Parvovirus B19 Infection ◽  
In Pregnancy

Case 39

2020 ◽  
pp. 269-276
Author(s):  
Katie Jeffery
Keyword(s):  
Viral Infection ◽  
Viral Infections ◽  
Parvovirus B19 ◽  
Adverse Outcomes ◽  
Varicella Zoster ◽  
Parvovirus B19 Infection ◽  
Diagnostic Approaches ◽  
In Pregnancy

Viral infection in pregnancy can lead to adverse outcomes for both the mother and the foetus. This chapter examines the steps to be taken on exposure to viruses associated with rash illness in pregnancy. Consideration is given to the important points in the history, which viral infections are of concern in pregnancy (varicella-zoster, parvovirus B19, rubella, measles, and Zika), the possible outcomes of infection, diagnostic approaches, and the management of a confirmed case of Parvovirus B19 infection.

scholarly journals Limited Open Reduction and Internal Fixation of Calcaneal Fractures

2019 ◽  
Vol 41 (1) ◽  
pp. 57-62 ◽  
Author(s):  
Anne K. Bremer ◽  
Lukas Kraler ◽  
Lars Frauchiger ◽  
Fabian G. Krause ◽  
Martin Weber
Keyword(s):  
Wound Healing ◽  
Internal Fixation ◽  
Open Reduction ◽  
Case Series ◽  
Functional Results ◽  
High Rate ◽  
Calcaneal Fractures ◽  
Retrospective Case ◽  
Level Of Evidence

Background: The treatment of displaced intra-articular calcaneal fractures remains a challenge and the optimal approach is still controversial. The main reason to avoid the extended lateral approach is the high complication rate due to wound healing problems. We report on 16 years of experience with a standardized limited open reduction and internal fixation technique. Methods: Between 2001 and 2017, we prospectively followed 240 consecutive patients operatively treated for a displaced intra-articular calcaneal fracture. Patients with open, multiple, bilateral, extra-articular, and Sanders IV fractures and those lost to follow-up were excluded. A lateral subtalar approach was used, with a cast for 8 weeks and full weightbearing allowed after 12 weeks. Follow-up examinations were scheduled until 24 months. Subjective and clinical assessment included gait abnormality, subtalar and ankle range of motion, and stability and alignment. The American Orthopaedic Foot & Ankle Society (AOFAS) hindfoot score was calculated. Alignment was analyzed on standard radiographs. In total, 131 patients were excluded. The remaining 109 patients were followed for a minimum of 24 months (34.4 ± 14.2 [range, 24-102] months). Results: The mean AOFAS score was 87 ± 13 (range, 32-100). “Excellent” and “good” results, as well as hindfoot motion with “normal/mild” and “moderate” restrictions, were seen in 80% of patients. Early reoperations were performed for insufficient reduction (2 patients), delayed wound healing (debridement, 3 patients), and hematoma (1 patient). Late revisions were arthrodesis (3 patients), medializing calcaneal osteotomy (1 patient), and implant removal (53 patients; 49%). Conclusion: The presented approach has remained unmodified for 16 years and resulted in consistently good functional results. The main disadvantage was the high rate of heel screw removal. Level of Evidence: Level IV, retrospective case series.

Sign in / Sign up

Export Citation Format

Share Document