scholarly journals Liposarcoma of the Nasopharynx: Diagnosis and Management of a Rare Diagnostic Entity

2012 ◽  
Vol 2012 ◽  
pp. 1-6 ◽  
Author(s):  
George X. Papacharalampous ◽  
Dimitrios Kikidis ◽  
Alexios Vasileiou ◽  
Aggeliki Bousiotou ◽  
Aristeidis Chrysovergis
Keyword(s):  
Head And Neck ◽  
Imaging Modality ◽  
English Literature ◽  
Soft Tissue Sarcomas ◽  
Macroscopic Appearance ◽  
Radiographic Findings ◽  
Diagnosis And Management ◽  
Complete Surgical Excision ◽  
Imaging Characteristics

Liposarcoma is one of the most frequently occurring soft tissue sarcomas in adulthood. The majority of liposarcomas arise in the lower extremities and retroperitoneum, while the incidence of this tumor in the head and neck region is reported to be extremely low, comprising 1.8%–6.2% of all cases. Nasopharyngeal liposarcoma is exceptionally rare, with only three cases having been reported in the English literature. This paper presents a case of a nasopharyngeal liposarcoma, treated with endoscopic tumor debulking, followed by adjuvant chemotherapy and radiotherapy, and reviews the current literature with regard to diagnosis and management of such lesions. Most authors agree that the imaging modality of choice is magnetic resonance imaging. Although radiographic findings usually support diagnosis, the imaging characteristics of such lesions may considerably vary, depending on the histological subtype and the macroscopic appearance of the tumor. The treatment of choice is complete surgical excision when possible. Although the role of postoperative radiotherapy is not clearly defined, some authors support that radiotherapy might delay or prevent local recurrence. However, there is no adequate evidence that the combination of surgery and radiotherapy lowers the possibility of distant metastasis of the head and neck liposarcomas. The role of adjuvant or neoadjuvant chemotherapy still remains controversial.

The role of surgery and radiotherapy in treatment of soft tissue sarcomas of the head and neck region: Review of 30 cases

2009 ◽  
Vol 37 (1) ◽  
pp. 42-48 ◽  
Author(s):  
Merdan Fayda ◽  
Gorkem Aksu ◽  
Fulya Yaman Agaoglu ◽  
Ahmet Karadeniz ◽  
Emin Darendeliler ◽  
...  
Keyword(s):  
Soft Tissue ◽  
Head And Neck ◽  
Soft Tissue Sarcomas ◽  
Neck Region ◽  
Head And Neck Region

Keratoacanthoma of the Head and Neck

1980 ◽  
Vol 89 (1) ◽  
pp. 72-74 ◽  
Author(s):  
Richard E. Goodwin ◽  
George H. Fisher
Keyword(s):  
Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Head And Neck ◽  
Squamous Cell ◽  
Surgical Excision ◽  
Clinical Entity ◽  
Diagnosis And Management ◽  
Difficult Diagnosis ◽  
Disease Spectrum ◽  
Complete Surgical Excision

Four representative cases of keratoacanthoma of the head and neck are presented; one of which contained squamous cell carcinoma at its base. Although keratoacanthoma has become recognized as a distinct clinical entity, its similarities to squamous cell carcinoma frequently result in difficult diagnosis. A discussion of the disease spectrum, diagnosis and management is presented. Prompt and complete surgical excision of head and neck keratoacanthoma is recommended.

Necrotizing fasciitis of the head and neck: role of CT in diagnosis and management.

Radiology ◽  
1997 ◽  
Vol 202 (2) ◽  
pp. 471-476 ◽  
Author(s):  
M Becker ◽  
P Zbären ◽  
R Hermans ◽  
C D Becker ◽  
F Marchal ◽  
...  
Keyword(s):  
Necrotizing Fasciitis ◽  
Head And Neck ◽  
Diagnosis And Management

Current update on the diagnosis and management of head and neck soft tissue sarcomas

2017 ◽  
Vol 46 (9) ◽  
pp. 674-679 ◽  
Author(s):  
Ben Tudor-Green ◽  
Ricardo Gomez ◽  
Peter A. Brennan
Keyword(s):  
Soft Tissue ◽  
Head And Neck ◽  
Soft Tissue Sarcomas ◽  
Diagnosis And Management

scholarly journals Role of Optical Coherence Tomography Angiography in the Diagnosis and Management of Wet Age-Related Macular Degeneration

QJM ◽  
2020 ◽  
Vol 113 (Supplement_1) ◽  
Author(s):  
F M Zaher ◽  
M G Metwally ◽  
B F Aziz ◽  
Y Z Abdelwadood
Keyword(s):  
Optical Coherence Tomography ◽  
Macular Degeneration ◽  
Optical Coherence Tomography Angiography ◽  
Imaging Modality ◽  
Age Related Macular Degeneration ◽  
Optical Coherence ◽  
Diagnosis And Management ◽  
Age Related ◽  
Wet Amd

Abstract Background Neo-vascular age-related macular degeneration (nAMD) (an advanced form of macular degeneration) is the main cause of visual impairment in older adults related to AMD. WHO has estimated that approximately 8 million people will be affected by AMD by the year 2020. Optical coherence tomography angiography (OCTA) is a novel imaging modality that permits direct visualization of the retinal and choroidal vasculature in vivo. In OCTA, high-frequency and dense volumetric scanning are made to detect blood flow by analyzing the signal decorrelation between scans. Compared with stationary areas of the retina, the movement of erythrocytes within a vessel makes a decorrelated signal. Unlike traditional angiography, OCTA does not necessitate the use of exogenous dyes, so avoiding potential side effects, such as nausea or other more serious adverse events. However, the role of OCTA as a diagnostic tool has not been largely investigated. Particularly, very few clinical studies have assessed the accuracy of OCTA imaging for the diagnosis of nAMD. Aim of the Work To highlight the benefits of using OCT-A in the diagnosis and management of wet AMD and compare it with the conventional angiographic standard, fundus fluorescein angiography (FFA). Subjects and Methods An interventional prospective comparative study will be conducted on 40 eyes diagnosed with wet AMD. Optical coherence tomography angiography and FFA will be done for all eyes. Analysis of the data obtained from the OCT-A will be done and compared with the standard FFA. Conclusion AMD is the leading cause of vision loss. Early detection and treatment is required. AMD is diagnosed by fundus examination, FA, and OCTA. OCTA and FA imaging provide complementary information about pathological changes in chorioretinal diseases. OCTA is highly sensitive for identifying AMD, CNV, and CNV activity; however, it cannot fully replace FA in the diagnosis of AMD.

scholarly journals Imaging in Head and Neck Cancers

2010 ◽  
Vol 2 (1) ◽  
pp. 15-23 ◽  
Author(s):  
Deepak Patkar ◽  
Malini Lawande ◽  
Rama Yanamandala
Keyword(s):  
Head And Neck Cancer ◽  
Head And Neck ◽  
Treatment Planning ◽  
Neck Cancer ◽  
Head And Neck Cancers ◽  
Imaging Modalities ◽  
Response To Treatment ◽  
Tissue Samples ◽  
Imaging Characteristics

Abstract This article reviews the role of imaging, imaging characteristics and significance of individual imaging modalities as well as the newer imaging modalities in the evaluation of head and neck cancer. In the pretreatment evaluation, imaging is performed primarily to determine the stage of tumor and to look for an occult primary. It helps in obtaining tissue samples to establish the diagnosis, and treatment planning if radiotherapy is considered. Postsurgery and radiotherapy changes can be differentiated from residual or recurrent pathology on imaging. Imaging also plays an important role in assessing the response to treatment.

The role of surgery and radiotherapy in treatment of soft tissue sarcomas of the head and neck region: Review of 30 cases

2007 ◽  
Vol 25 (18_suppl) ◽  
pp. 20507-20507
Author(s):  
F. Tas ◽  
M. Fayda ◽  
G. Aksu ◽  
F. Y. Agaoglu ◽  
A. Karadeniz ◽  
...  
Keyword(s):  
Soft Tissue ◽  
Head And Neck ◽  
Surgical Resection ◽  
Local Control ◽  
Residual Disease ◽  
Postoperative Radiotherapy ◽  
Soft Tissue Sarcomas ◽  
Neck Region ◽  
Head And Neck Region

20507 Background: To evaluate the role of surgery and radiotherapy in the treatment of soft tissue sarcomas of the head and neck region Methods: Thirty adult patients with head and neck soft tissue sarcoma were retrospectively analyzed. The most frequent histopathologic subtypes were chondrosarcomas (27%) and malignant fibrous histiocytoma (20%). The surgical resection was performed in 25 of the 30 patients (83%). Negative surgical margins could be achieved only in 9 of 25 patients (36%). Ten patients had marginal resection (40%) and 6 patients (24%) had gross residual disease after the surgery. All patients in the surgical resection arm received postoperative radiotherapy except two patients. Results: Five-year local control rates for patients with negative surgical margins (n=9), microscopically positives (n=10), gross residual disease (n=6) and inoperable (n=5) cases were 64%, 70%, 20% and 0% respectively. The median disease free survivals were 26.6 months, 17.7 months, 8.4 and 5.5 months. However, there was no significant difference in local control between patients with negative or microscopically positive disease who receive postoperative radiotherapy (71% vs 70%). The higher dose of radiotherapy (= 60Gy) was found to be associated with a longer local control (p=0.048). The local control rates were lower in patients with grade 2–3 tumors as compared with grade 1 tumors (44% vs. 83%). The median overall survival of whole group was 31 months. Median survivals of patients receiving both surgery and radiotherapy with negative and microscopically positive margins were significantly better than patients who were not treated with surgery (34.8 and 36 months vs. 13.3 months). In univariate analysis grade 1–2 vs. 3, had statistically significant 5-year survival difference (64% vs. 14%, p=0.003). The presence of local relapse had clear negative effect on survival (absent vs. present 66% vs. 7%, p=0.0003). Conclusions: Our results and the findings in the literature confirm that the optimal treatment of head and neck soft tissue sarcomas is complete surgical excision. Postoperative adjuvant radiotherapy clearly improves local control however the high locoregional failure rates still indicate the need for improved treatment strategies. No significant financial relationships to disclose.

Synchronous bilateral tonsillar carcinoma: role of fluoro-deoxyglucose positron emission tomography scanning in detecting occult primary tumours in metastatic nodal disease of the head and neck

2006 ◽  
Vol 120 (4) ◽  
pp. 334-337 ◽  
Author(s):  
T Price ◽  
J Pickles
Keyword(s):  
Positron Emission Tomography ◽  
Head And Neck ◽  
English Literature ◽  
Primary Tumour ◽  
Emission Tomography ◽  
Nodal Disease ◽  
Positron Emission Tomography Scanning ◽  
Positron Emission ◽  
Tomography Scanning

We present the second case of primary synchronous bilateral tonsillar squamous cell carcinoma reported in the English literature and evaluate the role of fluoro-deoxyglucose positron emission tomography scanning in the search for the occult primary tumour in a patient presenting with metastatic nodal disease in the head and neck.

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