scholarly journals A Synthetic Route to Quaternary Pyridinium Salt-Functionalized Silsesquioxanes

2012 ◽  
Vol 2012 ◽  
pp. 1-9 ◽  
Author(s):  
Nataliya Kostenko ◽  
Jochen Gottfriedsen ◽  
Liane Hilfert ◽  
Frank T. Edelmann
Keyword(s):  
Pyridinium Salt ◽  
High Yield ◽  
Synthetic Route ◽  
Alkylation Reactions ◽  
Partial Success

A synthetic route to potentially biocidal silsesquioxanes functionalized by quaternary pyridinium functionalities has been developed.N-Alkylation reactions of the precursor compounds 4-(2-(trimethoxysilyl)ethyl)-pyridine (5) and 4-(2-trichloro-silylethyl)pyridine (6) with iodomethane,n-hexylbromide, andn-hexadecylbromide cleanly afforded the correspondingN-alkylpyridinium salts (7–10). The synthesis of a 4-(2-ethyl)pyridine POSS derivative (2) was achieved by capping of the silsesquioxane trisilanol Cy7Si7O9(OH)3(1) via two different preparative routes. Attempts to use compound2as precursor for quaternary pyridinium salt-functionalized POSS derivatives were met with only partial success. Only the reaction with iodomethane cleanly afforded the newN-methylpyridinium salt12in high yield, whereasn-hexylbromide andn-hexadecylbromide failed to react with2even under forcing conditions.

Synthesis, Processing and Phase Evolution of TiN/TiB2 Composites From Polymeric Precursors

1992 ◽  
Vol 286 ◽  
Author(s):  
M. Nowakowski ◽  
K. Su ◽  
L. Sneddon ◽  
D. Bonnell
Keyword(s):  
Phase Evolution ◽  
High Yield ◽  
Microstructural Development ◽  
Synthetic Route ◽  
Polymeric Precursors

ABSTRACTA high yield synthetic route to TiN/TiB2 nanocomposites based upon polymeric precursors has been developed. The phase evolution and microstructural development have been characterized and related to preliminary measurements of properties, i.e. hardness. The observations indicate the existence of TiN-TiB2, TiN-BN, and TiB2-BN subsolidus compatibilities.

scholarly journals Full N,N-Methylation of 4,4′-Methylenedianiline with Dimethyl Carbonate: A Feasible Access to 4,4′-Methylene bis(N,N-Dimethylaniline)

2018 ◽  
Vol 2018 ◽  
pp. 1-10
Author(s):  
Zegang Qiu ◽  
Kunjie Wang ◽  
Zhiqin Li ◽  
Tao Li ◽  
Jinhao Bai ◽  
...  
Keyword(s):  
Zinc Acetate ◽  
Dimethyl Carbonate ◽  
Reaction Pathway ◽  
Major Product ◽  
High Yield ◽  
Synthetic Route ◽  
Reaction Conditions ◽  
High Yields ◽  
By Products

The full N,N-methylation of 4,4′-methylenedianiline (MDA) with dimethyl carbonate (DMC) was investigated. The yield of the major product 4,4′-methylene bis(N,N-dimethylaniline) (MBDMA) reached as high as 97% over NaY catalyst at 190°C for 6 h. The catalyst could be used for two more times with acceptable MBDMA yields higher than 90%. The main by-products were identified as three N-methylated derivatives. Surprisingly, the formation of the N-methoxycarbonylation product was extremely restrained, which could be produced in high yields of 98% on zinc acetate catalyst. Furthermore, the reaction pathway to the major product MBDMA was proposed. Finally, a feasible synthetic route of 4,4′-methylene bis(N,N-dimethylaniline) (MBDMA) was established, featuring a high yield, mild reaction conditions, and simple operations.

Facile Synthetic Route for Direct Access of Perylenediimide Single Crystals in High Yield through In Situ Crystallization

2020 ◽  
Vol 5 (6) ◽  
pp. 2070-2074
Author(s):  
Jayaraman Pitchaimani ◽  
Anu Kundu ◽  
Savarimuthu Philip Anthony ◽  
Dohyun Moon ◽  
Vedichi Madhu
Keyword(s):  
Single Crystals ◽  
Direct Access ◽  
High Yield ◽  
Synthetic Route ◽  
In Situ Crystallization

scholarly journals Synthesis and Intramolecular Energy- and Electron-Transfer of 3D-Conformeric Tris(fluorenyl-[60]fullerenylfluorene) Derivatives

Molecules ◽  
2019 ◽  
Vol 24 (18) ◽  
pp. 3337
Author(s):  
He Yin ◽  
Min Wang ◽  
Loon-Seng Tan ◽  
Long Y. Chiang
Keyword(s):  
Electron Transfer ◽  
Direct Contact ◽  
Photophysical Properties ◽  
Molecular Packing ◽  
The Self ◽  
High Yield ◽  
Synthetic Route ◽  
Quenching Effect ◽  
Shape Structure ◽  
Energy And Electron Transfer

New 3D conformers were synthesized to show a nanomolecular configuration with geometrically branched 2-diphenylaminofluorene (DPAF-C2M) chromophores using a symmetrical 1,3,5-triaminobenzene ring as the center core for the connection of three fused DPAF-C2M moieties. The design led to a class of cis-cup-tris[(DPAF-C2M)-C60(>DPAF-C9)] 3D conformers with three bisadduct-analogous <C60> cages per nanomolecule facing at the same side of the geometrical molecular cis-cup-shape structure. A sequential synthetic route was described to afford this 3D configurated conformer in a high yield with various spectroscopic characterizations. In principle, a nanostructure with a non-coplanar 3D configuration in design should minimize the direct contact or π-stacking of fluorene rings with each other during molecular packing to the formation of fullerosome array. It may also prevent the self-quenching effect of its photoexcited states in solids. Photophysical properties of this cis-cup-conformer were also investigated.

High yield "one-pot" synthesis of 2-hydroxy-3-methylcyclopent-2-en-1-one and related compounds

1982 ◽  
Vol 60 (5) ◽  
pp. 572-573 ◽  
Author(s):  
George M. Strunz ◽  
G. Sankar Lal
Keyword(s):  
High Yield ◽  
Synthetic Route ◽  
One Pot ◽  
One Pot Synthesis ◽  
Related Compounds

A convenient "one-pot" modification of a conventional synthetic route affords 2-hydroxy-3-methylcyclopent-2-en-1-one and related compounds in high overall yields.

A facile synthetic route for antineoplastic drug GDC-0449

2014 ◽  
Vol 68 (10) ◽  
Author(s):  
Meng Cao ◽  
Hua-You Hu ◽  
Hu-Cheng Zhao ◽  
Xi-Quan Zhang ◽  
Hong-Mei Gu ◽  
...  
Keyword(s):  
Nitro Group ◽  
Intermediate Product ◽  
Cross Coupling ◽  
Antineoplastic Drug ◽  
High Yield ◽  
Synthetic Route ◽  
Reaction Conditions ◽  
Final Compound

AbstractIn the current study a facile synthetic route for preparing antineoplastic drug GDC-0449 is investigated. Starting with pyridine-1-oxide and 1-iodo-3-nitrobenzene, the intermediate product 2-(2-chloro-5-nitrophenyl) pyridine was prepared by cross-coupling, deoxidation and halogenation. The final compound was then synthesised by reduction of the nitro group followed by amidation. This synthetic route avoids the use of unstable organometallic or organic boride compounds; it employs relatively inexpensive and bench-stable reagents, involves readily controllable reaction conditions, and achieves a relatively high yield.

A new high-yield synthetic route to PET CB1 radioligands [11C]OMAR and its analogs

2012 ◽  
Vol 22 (11) ◽  
pp. 3704-3709 ◽  
Author(s):  
Mingzhang Gao ◽  
Min Wang ◽  
Qi-Huang Zheng
Keyword(s):  
High Yield ◽  
Synthetic Route

scholarly journals Janus bis(NHCs) tuned by heteroatom-bridge oxidation states

2020 ◽  
Vol 56 (17) ◽  
pp. 2646-2649
Author(s):  
Nabila Rauf Naz ◽  
Gregor Schnakenburg ◽  
Antal Mikeházi ◽  
Zsolt Kelemen ◽  
László Nyulászi ◽  
...  
Keyword(s):  
Oxidation States ◽  
High Yield ◽  
Synthetic Route ◽  
Coinage Metal ◽  
Potential Use

Synthesis of the first tricyclic bis(carbenes) with facially opposed imidazole-2-ylidenes and two linking phosphorus centres in different oxidation states is presented using a modular, high-yield synthetic route. The formation of homo bimetallic coinage metal(i) complexes provides a first glimpse on their potential use.

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