scholarly journals May Salivary Alpha-Amylase Level Be a Useful Tool for Assessment of the Severity of Schizophrenia and Evaluation of Therapy? A Case Report

2012 ◽  
Vol 2012 ◽  
pp. 1-4 ◽  
Author(s):  
Masa Ieda ◽  
Tsuyoshi Miyaoka ◽  
Kiminori Kawano ◽  
Rei Wake ◽  
Takuji Inagaki ◽  
...  
Keyword(s):  
Nervous System ◽  
Case Report ◽  
Psychiatric Symptoms ◽  
Alpha Amylase ◽  
Amylase Level ◽  
Salivary Alpha Amylase ◽  
Psychotic State ◽  
Catatonic Schizophrenia ◽  
Normal Controls ◽  
Efficacy Of Treatment

Background. Previous studies suggested dysfunction of the autonomic nervous system (ANS) in schizophrenia patients, but the mechanism remains unclear. Recently, the measurement of salivary alpha-amylase (sAA) has been considered a useful tool for evaluating ANS, especially the sympathoadrenal medullary system. Furthermore, there was a report that patients with schizophrenia showed much higher sAA level than normal controls.Methods. We present the case of a 51-year-old female with catatonic schizophrenia. She needed the treatment of electroconvulsive therapy (ECT). We evaluated her sAA level and her psychiatric symptoms during the treatment.Results. Before ECT treatment, she showed high sAA level. Her sAA level decreased during the course of ECT, and this attenuation was accompanied by improvement of schizophrenic symptoms.Conclusion. We consider that measurement of the sAA level may be one of the useful biological markers for assessment of psychotic state and efficacy of treatment in patients with schizophrenia.

scholarly journals CORRELATION BETWEEN WONG-BAKER FACES PAIN SCALE AND SALIVARY ALPHA-AMYLASE LEVEL IN CHILDREN AGED 6–11 YEARS

2018 ◽  
Vol 9 ◽  
pp. 133
Author(s):  
Hastin Dian Anggraeni ◽  
Margaretha Suharsini ◽  
Ike Siti Indiarti ◽  
Faraghea Yumasdhika
Keyword(s):  
Pain Intensity ◽  
Local Anesthetic ◽  
Extraction Procedure ◽  
Pain Scale ◽  
Alpha Amylase ◽  
Primary Tooth ◽  
Amylase Level ◽  
Salivary Alpha Amylase ◽  
Local Anesthetic Injection ◽  
Spearman’S Correlation

Objective: Several studies have tried to objectively assess pain measurements. The Wong-Baker Faces Pain Scale (WBFPS) is an instrument that is commonly used to assess pain intensity in children. This study aimed to analyze the correlation between the WBFPS and salivary alpha-amylase (SAA) level during a tooth extraction procedure with a local anesthetic injection in children aged 6–11 years.Methods: Twenty-five children aged 6–11 years who were to undergo the extraction of a primary tooth at the Dental and Oral Educational Hospital, Faculty of Dentistry Universitas Indonesia, were enrolled in this study. From all children, saliva was collected using a disposable saliva strip shortly after local anesthetic injection, and the SAA activity was then determined using a portable Nipro Cocoro Meter device. The WBFPS was measured at the same time. The correlation between the WBFPS and the SAA level was analyzed using Spearman’s correlation test. The statistically significant level was set at p≤0.05.Results: There was a significant correlation between the WBFPS and SAA level (p=0.002, r=0.581).Conclusion: Our data suggest that the SAA level might be a good index for objective pain intensity assessment.

scholarly journals Correlation of Salivary Alpha Amylase Level and Adenotonsillar Hypertrophy with Sleep Disordered Breathing in Pediatric Subjects

2014 ◽  
Vol 10 (05) ◽  
pp. 559-566 ◽  
Author(s):  
Chan-Soon Park ◽  
Christian Guilleminault ◽  
Hong-Jin Park ◽  
Jin-Hee Cho ◽  
Heung-Ku Lee ◽  
...  
Keyword(s):  
Sleep Disordered Breathing ◽  
Alpha Amylase ◽  
Amylase Level ◽  
Salivary Alpha Amylase ◽  
Adenotonsillar Hypertrophy ◽  
Disordered Breathing

scholarly journals Altered Salivary Alpha-Amylase Secretion in Patients with Ulcerative Colitis

2018 ◽  
Vol 2018 ◽  
pp. 1-6 ◽  
Author(s):  
Zhuoni Xu ◽  
Baoping Wei ◽  
Yanting Qiu ◽  
Tao Zhang
Keyword(s):  
Ulcerative Colitis ◽  
Nervous System ◽  
Copy Number ◽  
Nervous Activity ◽  
Alpha Amylase ◽  
Gene Copy ◽  
Anxiety And Depression ◽  
Amylase Secretion ◽  
Salivary Alpha Amylase ◽  
Sympathetic Nervous

Purpose. Patients with ulcerative colitis (UC) frequently present with psychological disturbances as well as dysfunctions of autonomic nervous system (ANS). Salivary alpha-amylase (sAA) secretion is predominantly controlled by sympathetic nervous activity, while salivary fluid secretion is by parasympathetic nervous activity. Thus, it is speculated that alterations of salivary secretion may be addressed in UC populations. Methods. Thirty-five UC patients as well as 32 age- and sex-matched healthy controls were enrolled. Saliva samples before and after citric acid stimulation were collected from each participant, and salivary flow rate (SFR) was calculated accordingly. Western blotting and quantitative PCR were applied to measure the sAA level and sAA gene (AMY1) copy number, respectively. The psychological disorders, anxiety and depression, were evaluated by the scoring system of Hospital Anxiety and Depression Scale (HADS) for each participant. Results. We observed robustly increased prevalence of anxiety (p<0.001) as well as depression (p<0.001) in UC patients relative to controls. Interestingly, we detected elevated basal (p=0.015) and stimulated (p=0.021) sAA levels in the UC populations compared to controls. However, no differences were found for basal (p=0.643) or stimulated (p=0.402) SFR between the two study groups. Besides, AMY1 gene copy number was comparable between UC patients and controls. Conclusions. Our results reveal an overactivity of the sympathetic nervous system and a normal activity of the parasympathetic nervous system in the UC population.

Enhancement of the efficiency of a salivary alpha amylase biomarker for the sympathetic nervous system by a nano-optical sensor Tb–acetyl acetone complex

2016 ◽  
Vol 40 (9) ◽  
pp. 7529-7535 ◽  
Author(s):  
Mohamed S. Attia ◽  
Ahmed O. Youssef
Keyword(s):  
Nervous System ◽  
Sympathetic Nervous System ◽  
Optical Sensor ◽  
Alpha Amylase ◽  
Salivary Alpha Amylase ◽  
Acetyl Acetone ◽  
Sympathetic Nervous

A new nano-optical sensor Tb–acetylacetone (Tb–ACAC) complex is developed for assessing the activity of a salivary alpha amylase enzyme.

scholarly journals Comparison of salivary alpha-amylase levels in gingivitis and periodontitis

2017 ◽  
Vol 50 (4) ◽  
pp. 216
Author(s):  
Dyah Nindita Carolina ◽  
Yanti Rusyanti ◽  
Agus Susanto
Keyword(s):  
Periodontal Disease ◽  
Inflammatory Disease ◽  
Descriptive Study ◽  
The Other ◽  
Alpha Amylase ◽  
Amylase Level ◽  
Salivary Amylase ◽  
Salivary Alpha Amylase ◽  
The Difference ◽  
Paired T Test

Background: The development of periodontal disease is influenced by bacteria-plaque, while there are also several factors modifying the host’s response, one of which is psychological stress. Alpha-amylase as a biomarker is also associated with periodontal inflammatory disease. Purpose: The purpose of this study was to examine the difference of alpha-amylase level between gingivitis and periodontitis. Methods: This research constitutes a descriptive study involving 44 subjects, divided into two groups: one of 22 gingivitis subjects and the other of 22 periodontitis subjects. These individuals completed a PSS-14 questionnaire before their levels of alpha salivary amylase were measured by Cocorometer. Data was analyzed by means of a paired T test and a Mann Whitney test with p < 0.05. Results: There were significant differences between the alpha-amylase levels of gingivitis and periodontitis. However, no significant contrast existed in the PSS-14 scores of the two periodontal disease groups. Conclusion: In conclusion alpha-amylase levels in the periodontitis group were higher than those in the gingivitis group and could be used as marker indicators of stress.

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