scholarly journals Unusual Respiratory Manifestations in Two Young Adults with Duchenne Muscular Dystrophy

2012 ◽  
Vol 19 (1) ◽  
pp. 37-40 ◽  
Author(s):  
Julie Lemay ◽  
Frédéric Sériès ◽  
Mario Sénéchal ◽  
Bruno Maranda ◽  
François Maltais

Adult respirologists are often involved in the evaluation and treatment of young adult patients with Duchenne muscular dystrophy. In this context, the most frequent respiratory complication is nocturnal and daytime hypoventilation related to respiratory muscle weakness. The present article describes cases of Duchenne muscular dystrophy involving two brothers, 17 and 19 years of age, respectively, who presented with less frequently reported respiratory complications of their disease: obstructive sleep apnea and Cheyne-Stokes respiration with central apnea, which were believed to be partially or completely related to congestive cardiomyopathy.

2020 ◽  
Vol 1 (2) ◽  
pp. 17-20
Author(s):  
Fidela Hanan Zivana

Background: Obstructive Sleep Apnea Syndrome (OSAS) is sleeping-disorder that’s characterized by recurrent episodes of upper airway obstruction during sleep. Fourteen percent of world populations suffer from OSAS. OSA patients are 7,5 to 20 times more likely to have difficulties with concentration, learning new tasks, and execution of monotonous tasks.Objective: The primary objective of this study was to investigate the relationship between Obstructive Sleep Apnea Syndrome (OSAS) and concentration level in young adults.Methods: This is an analytic observational study with cross-sectional design. Sampling was carried out with total sampling. Samples that qualified the inclusion and exclusion criteria were assessed by OSAS using the Epworth Sleepiness Scale (ESS)  questionnaire and Digit Symbol Substitution Test was used to assess the concentration level. The data were analyzed, using the chi-square test and the prevalence (PR) test.Results: The Chi-square test showed that there was a significant relationship between OSAS and concentration level (p=0.033). The Prevalence Ratio test found that OSAS decreased concentration level by 1,55 compared to not OSAS.Conclusion:  There was a significant relationship between OSAS and concentration level in young adults. OSAS patients are 1,55 more likely to have a decrease concentration level when compared with healthy individuals.


Ophthalmology ◽  
2019 ◽  
Vol 126 (10) ◽  
pp. 1372-1384 ◽  
Author(s):  
Samantha S.Y. Lee ◽  
Nigel McArdle ◽  
Paul G. Sanfilippo ◽  
Seyhan Yazar ◽  
Peter R. Eastwood ◽  
...  

2003 ◽  
Vol 99 (3) ◽  
pp. 586-595 ◽  
Author(s):  
Karen A. Brown ◽  
Isabelle Morin ◽  
Chantal Hickey ◽  
John J. Manoukian ◽  
Gillian M. Nixon ◽  
...  

Background The aim of this study was to determine the frequency and type of respiratory complications after urgent adenotonsillectomy (study group) for comparison with a control group of children undergoing a sleep study and adenotonsillectomy for obstructive sleep apnea syndrome. A second aim was to assess risk factors predictive of respiratory complications after urgent adenotonsillectomy. Methods The perioperative course of children who underwent adenotonsillectomy between January 1, 1999, and March 31, 2001, was reviewed. Two groups of children were identified from two different databases: the hospital database for surgical procedures (the study group) and the sleep laboratory database (the control group). The retrospective chart review focused on the preoperative status (including an evaluation for obstructive sleep apnea), anesthetic management, and need for postoperative respiratory interventions. Results A total of 64 consecutive cases for urgent adenotonsillectomy were identified, and 54 children met the inclusion criteria. Thirty-three children (60%) had postoperative respiratory complications necessitating a medical intervention; 11 (20.3%) required a major intervention (reintubation, ventilation, and/or administration of racemic epinephrine or Ventolin), and 22 (40.7%) required a minor intervention (oxygen administration). Six children (11.1%) required reintubation in the recovery room for respiratory compromise. Risk factors for respiratory complications were an associated medical condition (odds ratio, 8.15; 95% confidence interval, 1.81-36.73) and a preoperative saturation nadir less than 80% (odds ratio, 5.54; 95% confidence interval, 1.15-26.72). Sixteen (49%) of the medical interventions were required within the first postoperative hour. Atropine administration, at induction, decreased the risk of postoperative respiratory complications (odds ratio, 0.18; 95% confidence interval, 0.11-1.050. Control Group Of 75 children who underwent a sleep study and adenotonsillectomy, 44 had sleep apnea and were admitted to hospital after elective adenotonsillectomy. Sixteen (36.4%) children had postoperative respiratory complications necessitating a medical intervention. Six percent of the children (n = 3) required a major medical intervention. No child required reintubation for respiratory compromise. Conclusions Severe obstructive sleep apnea syndrome and an associated medical condition are risk factors for postadenotonsillectomy respiratory complications. Risk reductions strategies should focus on their assessment.


2013 ◽  
Vol 27 (2) ◽  
pp. 229-236 ◽  
Author(s):  
Wipawan C. Pensuksan ◽  
Xiaoli Chen ◽  
Vitool Lohsoonthorn ◽  
Somrat Lertmaharit ◽  
Bizu Gelaye ◽  
...  

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