scholarly journals Repeated Bout Effect Was More Expressed in Young Adult Males Than in Elderly Males and Boys

2013 ◽  
Vol 2013 ◽  
pp. 1-10 ◽  
Author(s):  
Giedrius Gorianovas ◽  
Albertas Skurvydas ◽  
Vytautas Streckis ◽  
Marius Brazaitis ◽  
Sigitas Kamandulis ◽  
...  
Keyword(s):  
Creatine Kinase ◽  
Muscle Damage ◽  
Muscle Soreness ◽  
Repeated Bout Effect ◽  
Adult Males ◽  
Elderly Males ◽  
Dependent Variables ◽  
Drop Jumps ◽  
Exercise Induced ◽  
Repeated Bout

This study investigated possible differences using the same stretch-shortening exercise (SSE) protocol on generally accepted monitoring markers (dependent variables: changes in creatine kinase, muscle soreness, and voluntary and electrically evoked torque) in males across three lifespan stages (childhood versus adulthood versus old age). The protocol consisted of 100 intermittent (30 s interval between jumps) drop jumps to determine the repeated bout effect (RBE) (first and second bouts performed at a 2-week interval). The results showed that indirect symptoms of exercise-induced muscle damage after SSE were more expressed in adult males than in boys and elderly males, suggesting that the muscles of boys and elderly males are more resistant to exercise-induced damage than those of adult males. RBE was more pronounced in adult males than in boys and elderly males, suggesting that the muscles of boys and elderly males are less adaptive to exercise-induced muscle damage than those of adult males.

scholarly journals THE EFFECT OF DIFFERENT DOSE OF DROP JUMPING ON SYMPTOMS OF MUSCLE DAMAGE

2018 ◽  
Vol 1 (108) ◽  
pp. 25-29
Author(s):  
Albertas Skurvydas ◽  
Gediminas Mamkus ◽  
Dalia Mickevičienė ◽  
Diana Karanauskienė ◽  
Dovilė Valančienė ◽  
...  
Keyword(s):  
Creatine Kinase ◽  
Muscle Damage ◽  
Muscle Soreness ◽  
Knee Extension ◽  
Cycle Exercise ◽  
Healthy Men ◽  
Maximal Intensity ◽  
Drop Jumps ◽  
Stretch Shortening Cycle ◽  
Exercise Induced

Background. The aim of this study was to follow symptoms of exercise induced muscle damage in response to 50, 100 and 200 drop jumps with maximal intensity. Methods. Three groups of young healthy men (n = 10 in each group) performed a bout of mechanically demanding stretch shortening cycle exercise consisting of 50, 100 and 200 drop jumps. Voluntary and electrically induced knee extension torque, creatine kinase, muscle soreness were measured before and 24 h after exercise. Results. Indirect symptoms of exercise induced damage were dependent on DJs volume: the higher the numbers of jumps, the more symptoms were observed. Only after 200 DJs compared to 50-100 DJ there was decrease of CAR and H of DJ, and 24 h after 200 DJs CK was greater than after 50-100 DJs. Conclusion. In response to acute severe muscle-damaging exercise (after 200 DJs), indirect symptoms of exercise-induced muscle damage occurred.

scholarly journals Human alpha-actinin-3 genotype association with exercise-induced muscle damage and the repeated-bout effect

2012 ◽  
Vol 37 (6) ◽  
pp. 1038-1046 ◽  
Author(s):  
Tomas Venckunas ◽  
Albertas Skurvydas ◽  
Marius Brazaitis ◽  
Sigitas Kamandulis ◽  
Audrius Snieckus ◽  
...  
Keyword(s):  
Muscle Damage ◽  
Eccentric Exercise ◽  
Knee Extension ◽  
Repeated Bout Effect ◽  
Drop Jumps ◽  
Jumping Exercise ◽  
Exercise Induced ◽  
Torque Values ◽  
The Impact ◽  
Repeated Bout

Alpha-actinin-3 (ACTN3) is an integral part of the Z line of the sarcomere. The ACTN3 R577X (rs1815739) polymorphism determines the presence or absence of functional ACTN3, which may influence the extent of exercise-induced muscle damage. This study aimed to compare the impact of, and recovery from, muscle-damaging eccentric exercise on subjects with or without functional ACTN3. Seventeen young men (20–33 years old), homozygous for the R (n = 9) or X (n = 8) alleles, performed two bouts of stretch–shortening exercise (50 drop jumps) two weeks apart. Muscle soreness, plasma creatine kinase (CK) activity, jump height, maximal voluntary isometric torque (MVC), peak concentric isokinetic torque (IT), and electrically stimulated knee extension torques at 20 and 100 Hz were measured at baseline and at a number of time points up to 14 days after each bout. There were no significant baseline differences between the groups. However, significant time point × genotype interactions were observed for MVC (p = 0.021) and IT (p = 0.011) for the immediate effect of eccentric exercise in bout 1. The RR group showed greater voluntary force decrements (RR vs. XX: MVC, –33.3% vs. –24.5%; IT, –35.9% vs. –23.2%) and slower recovery. A repeated-bout effect was clearly observed, but there were no differences by genotype group. The ACTN3 genotype modulates the response of muscle function to plyometric jumping exercise, although the differences are modest. The ACTN3 genotype does not influence the clearly observed repeated-bout effect; however, XX homozygotes recover baseline voluntary torque values faster and thus may be able to undertake more frequent training sesssions.

scholarly journals The repeated bout effect of traditional resistance exercises on running performance across 3 bouts

2017 ◽  
Vol 42 (9) ◽  
pp. 978-985 ◽  
Author(s):  
Kenji Doma ◽  
Moritz Schumann ◽  
Anthony Scott Leicht ◽  
Brian Edward Heilbronn ◽  
Felipe Damas ◽  
...  
Keyword(s):  
Resistance Training ◽  
Muscle Damage ◽  
Muscle Soreness ◽  
Recovery Period ◽  
Repeated Bout Effect ◽  
Lower Body ◽  
Running Performance ◽  
The Third ◽  
Repeated Bout ◽  
Muscle Damage Markers

This study investigated the repeated bout effect of 3 typical lower body resistance-training sessions on maximal and submaximal effort running performance. Twelve resistance-untrained men (age, 24 ± 4 years; height, 1.81 ± 0.10 m; body mass, 79.3 ± 10.9 kg; peak oxygen uptake, 48.2 ± 6.5 mL·kg−1·min−1; 6-repetition maximum squat, 71.7 ± 12.2 kg) undertook 3 bouts of resistance-training sessions at 6-repetitions maximum. Countermovement jump (CMJ), lower-body range of motion (ROM), muscle soreness, and creatine kinase (CK) were examined prior to and immediately, 24 h (T24), and 48 h (T48) after each resistance-training bout. Submaximal (i.e., below anaerobic threshold (AT)) and maximal (i.e., above AT) running performances were also conducted at T24 and T48. Most indirect muscle damage markers (i.e., CMJ, ROM, and muscle soreness) and submaximal running performance were significantly improved (P < 0.05; 1.9%) following the third resistance-training bout compared with the second bout. Whilst maximal running performance was also improved following the third bout (P < 0.05; 9.8%) compared with other bouts, the measures were still reduced by 12%–20% versus baseline. However, the increase in CK was attenuated following the second bout (P < 0.05) with no further protection following the third bout (P > 0.05). In conclusion, the initial bout induced the greatest change in CK; however, at least 2 bouts were required to produce protective effects on other indirect muscle damage markers and submaximal running performance measures. This suggests that submaximal running sessions should be avoided for at least 48 h after resistance training until the third bout, although a greater recovery period may be required for maximal running sessions.

scholarly journals A single dose of histamine-receptor antagonists before downhill running alters markers of muscle damage and delayed-onset muscle soreness

2017 ◽  
Vol 122 (3) ◽  
pp. 631-641 ◽  
Author(s):  
Matthew R. Ely ◽  
Steven A. Romero ◽  
Dylan C. Sieck ◽  
Joshua E. Mangum ◽  
Meredith J. Luttrell ◽  
...  
Keyword(s):  
Blood Flow ◽  
Creatine Kinase ◽  
Muscle Strength ◽  
Muscle Damage ◽  
Muscle Soreness ◽  
Strength Loss ◽  
Histamine Receptor ◽  
Delayed Onset ◽  
Markers Of Inflammation ◽  
Exercise Induced

Histamine contributes to elevations in skeletal muscle blood flow following exercise, which raises the possibility that histamine is an important mediator of the inflammatory response to exercise. We examined the influence of antihistamines on postexercise blood flow, inflammation, muscle damage, and delayed-onset muscle soreness (DOMS) in a model of moderate exercise-induced muscle damage. Subjects consumed either a combination of fexofenadine and ranitidine (blockade, n = 12) or nothing (control, n = 12) before 45 min of downhill running (−10% grade). Blood flow to the leg was measured before and throughout 120 min of exercise recovery. Markers of inflammation, muscle damage, and DOMS were obtained before and at 0, 6, 12, 24, 48, and 72 h postexercise. At 60 min postexercise, blood flow was reduced ~29% with blockade compared with control ( P < 0.05). Markers of inflammation were elevated after exercise (TNF-ɑ, IL-6), but did not differ between control and blockade. Creatine kinase concentrations peaked 12 h after exercise, and the overall response was greater with blockade (18.3 ± 3.2 kU·l−1·h−1) compared with control (11.6 ± 2.0 kU·l−1·h−1; P < 0.05). Reductions in muscle strength in control (−19.3 ± 4.3% at 24 h) were greater than blockade (−7.8 ± 4.8%; P < 0.05) and corresponded with greater perceptions of pain/discomfort in control compared with blockade. In conclusion, histamine-receptor blockade reduced postexercise blood flow, had no effect on the pattern of inflammatory markers, increased serum creatine kinase concentrations, attenuated muscle strength loss, and reduced pain perception following muscle-damaging exercise. NEW & NOTEWORTHY Histamine appears to be intimately involved with skeletal muscle during and following exercise. Blocking histamine’s actions during muscle-damaging exercise, via common over-the-counter antihistamines, resulted in increased serum creatine kinase, an indirect marker of muscle damage. Paradoxically, blocking histamine’s actions attenuated muscle strength loss and reduced perceptions of muscle pain for 72 h following muscle-damaging exercise. These results indicate that exercise-induced histamine release may have a broad impact on protecting muscle from exercise-induced damage.

scholarly journals Serum cartilage oligomeric matrix protein: is there a repeated bout effect?

2014 ◽  
Vol 6 (3) ◽  
Author(s):  
Michael Behringer ◽  
Johannes Montag ◽  
Yvonne Kilian ◽  
Molly McCourt ◽  
Anna-Maria Liphardt ◽  
...  
Keyword(s):  
Cartilage Oligomeric Matrix Protein ◽  
Muscle Soreness ◽  
Matrix Protein ◽  
Cartilage Damage ◽  
Cartilage Tissue ◽  
Repeated Bout Effect ◽  
Drop Jumps ◽  
Maximum Pain ◽  
Male Subjects ◽  
Repeated Bout

The primary aim of the present study was to investigate if there is a repeated bout effect for cartilage tissue, evident in the marker serum cartilage oligomeric matrix protein (sCOMP). Ten healthy male subjects (26.4±3.14 years) performed two high impact interventions (100 drop jumps with a 30 second interval) carried out at a 3 week interval. After each intervention, sCOMP and muscle soreness were assessed on 8 and 6 occasions respectively. Muscle soreness was determined via a visual analog scale with a maximum pain score of 10. sComp levels did not show a blunted response after the second bout (Bout 1: 12.2±3.3 U/L−1; Bout 2: 13.1±4.0 U/L−1; P&gt;0.05). Remarkably, sCOMP increased from baseline levels by 16% after bout 1 and 15% after bout 2. Muscle soreness was blunted following the second intervention (Bout 1: 5.0±1.8; Bout 2: 1.6±0.8). Unlike the known repeated bout effect for muscle damage markers, sCOMP levels do not show a blunted response after two similar loading interventions. This information on biomarker behavior is essential to clinicians attempting to use this marker as an indicator of cartilage damage associated with the development or progression of osteoarthritis.

Exercise-Induced Muscle Damage and Potential Mechanisms for the Repeated Bout Effect

1999 ◽  
Vol 27 (3) ◽  
pp. 157-170 ◽  
Author(s):  
Malachy P. McHugh ◽  
Declan A.J. Connolly ◽  
Roger G. Eston ◽  
Gilbert W. Gleim
Keyword(s):  
Muscle Damage ◽  
Repeated Bout Effect ◽  
Exercise Induced ◽  
Repeated Bout

Predictive value of strength loss as an indicator of muscle damage across multiple drop jumps

2011 ◽  
Vol 36 (3) ◽  
pp. 353-360 ◽  
Author(s):  
Albertas Skurvydas ◽  
Marius Brazaitis ◽  
Tomas Venckūnas ◽  
Sigitas Kamandulis
Keyword(s):  
Muscle Damage ◽  
Predictive Value ◽  
Time Course ◽  
Muscle Soreness ◽  
Low Frequency ◽  
Knee Extensor ◽  
Strength Loss ◽  
Drop Jumps ◽  
Isokinetic Torque ◽  
Exercise Induced

The aim of the present study was to compare the time-course of indirect symptoms of exercise-induced muscle damage after 50 and 100 drop jumps. A high-force, low intensity exercise protocol was used to avoid discrepancies regarding metabolic fatigue immediately after exercise. Healthy untrained men performed 50 (“50 group”, n = 13) or 100 (“100 group”, n = 13) intermittent (30-s interval between each jump) drop jumps, respectively, from the height of 0.5 m with a counter-movement to a 90° knee flexion angle and immediate maximal rebound. Voluntary and electrically evoked knee extensor strength was assessed using an isokinetic dynamometer immediately before and at 2 min after exercise, as well as 3, 7, and 14 days after exercise. Creatine kinase (CK) activity and muscle soreness within 7 days after exercise were also determined. The results showed that the decrease in voluntary isometric and isokinetic torque as well as 100 Hz stimulation torque at the end of the 50 and 100 drop jumps was very similar, while substantial differences were found in low-frequency fatigue, shift in optimal knee joint angle, muscle soreness, and CK activity. In addition, there was slower muscle strength recovery after the 100 drop jumps. It is concluded that the predictive value of strength loss immediately after exercise as an indicator of muscle damage decreases as the jump number increases. Still, stimuli must be large enough for muscle torque to reach the reduction plateau. Therefore, magnitude of exercise becomes a major factor in accuracy of muscle damage predictions.

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