scholarly journals Fatal DisseminatedFusariumInfection in a Human Immunodeficiency Virus Positive Patient

2013 ◽  
Vol 2013 ◽  
pp. 1-5 ◽  
Author(s):  
Ashwini K. Esnakula ◽  
Irorere Summers ◽  
Tammey J. Naab

Systemic mycotic infections have been increasing in incidence in immunocompromised patients. Although yeasts are most often isolated, opportunistic fungal infections may also be caused by filamentous fungi, includingAspergillusandFusarium. LikeAspergillus,Fusariumis angioinvasive with an ability to disseminate widely. Disseminated fusariosis is most commonly linked to prolonged neutropenia. Disseminated infections due toFusariumare rare in Human Immunodeficiency Virus (HIV) positive patients but have been reported in HIV positive patients with neutropenia and lymphoma. We describe an HIV positive patient without neutropenia, skin lesions, or concomitant malignancy, who developed fatal disseminated infection with possible endocarditis due toFusarium solani. Early identification ofFusariumis important because of its high level of resistance to several antifungal drugs, with response often requiring combination therapy.

2000 ◽  
Vol 38 (9) ◽  
pp. 3460-3462 ◽  
Author(s):  
Josep Guarro ◽  
Marcio Nucci ◽  
Tiyomi Akiti ◽  
Josepa Gené

We report on a case of mixed infection caused by two species ofFusarium in a human immunodeficiency virus-positive patient with lymphoma who was neutropenic due to chemotherapy. The patient showed the typical signs of a disseminated fusarial infection, withFusarium solani isolated from skin lesions and F. verticillioides isolated from blood. The report discusses how difficult it is to make an accurate diagnosis when an immunosuppressed patient is infected with more than one fungal species, especially when the species are morphologically very similar.


2002 ◽  
Vol 116 (4) ◽  
pp. 288-290 ◽  
Author(s):  
C. V. Praveen ◽  
R. M. Terry ◽  
M. Elmahallawy ◽  
C. Horsfield

Pneumocystis carinii is an opportunistic infection found in patients with impaired immunity. Under favourable conditions the parasite can spread via the blood stream or lymphatic vessels and cause extrapulmonary dissemination. We report a case of P carinii infection presenting as bilateral aural polyps, otitis media and mastoiditis in human immunodeficiency (HIV)-positive patient with no history of prior or concomitant P carinii infection.


2006 ◽  
Vol 14 (5) ◽  
pp. 309-311 ◽  
Author(s):  
Thekla G. Papadaki ◽  
Chrysanthi Kafkala ◽  
Ioannis P. Zacharopoulos ◽  
Jian Seyedahmadi B ◽  
Thaddeus Dryja ◽  
...  

2009 ◽  
Vol 48 (2) ◽  
pp. 157-159 ◽  
Author(s):  
Marcello Menta S. Nico ◽  
Hermes Ryoiti Higashino ◽  
Ho Yeh Li ◽  
Noemia Barbosa Carvalho ◽  
Silvia Vanessa Lourenço

2000 ◽  
Vol 38 (10) ◽  
pp. 3595-3607 ◽  
Author(s):  
Kaaren Vargas ◽  
Shawn A. Messer ◽  
Michael Pfaller ◽  
Shawn R. Lockhart ◽  
Jack T. Stapleton ◽  
...  

Strains of Candida albicans obtained from human immunodeficiency virus (HIV)-positive individuals prior to their first episode of oral thrush were already in a high-frequency mode of switching and were far more resistant to a number of antifungal drugs than commensal isolates from healthy individuals. Switching in these isolates also had profound effects both on susceptibility to antifungal drugs and on the levels of secreted proteinase activity. These results suggest that commensal strains colonizing HIV-positive individuals either undergo phenotypic alterations or are replaced prior to the first episode of oral thrush. They also support the suggestion that high-frequency phenotypic switching functions as a higher-order virulence trait, spontaneously generating in colonizing populations variants with alterations in a variety of specific virulence traits.


2021 ◽  
Vol 429 ◽  
pp. 118363
Author(s):  
Alessandro Di Santo ◽  
Fabio Pilato ◽  
Fioravante Capone ◽  
Liana Africa ◽  
Vincenzo Di Lazzaro

2015 ◽  
Vol 5 ◽  
pp. 59 ◽  
Author(s):  
Guan Huang ◽  
Gavin Low

Human herpes virus-8 (HHV-8)–associated Castleman's disease (CD) is a rare non-cancerous B-cell lymphoproliferative disorder in human immunodeficiency virus (HIV)-positive patients. We report a case of HHV-8–associated CD in an HIV-positive patient with a previous history of Kaposi's sarcoma (KS). The patient presented with progressive splenomegaly and diffuse lymphadenopathy, which can be seen in multicentric CD, KS, and HIV-associated lymphoma. There are no reliable clinical or imaging features to differentiate these diseases. Lymph node biopsy confirmed HHV-8–associated CD and excluded KS and lymphoma. Due to differences in treatment options and prognosis between the three etiologies, it is important for radiologists to include HHV-8–associated CD in the differential diagnosis when encountering HIV-positive patients that present with diffuse lymphadenopathy.


2013 ◽  
Vol 3 (2) ◽  
pp. 51-54
Author(s):  
Padmavathi Devi Chaganti ◽  
YVS Prabhakar ◽  
KA Seetaram ◽  
Kalyan Babu

ABSTRACT A 33 years old male human immunodeficiency virus (HIV) positive patient on antiretroviral therapy developed caseating granulomatous inflammation of lymph nodes. He did not respond to antituberculous treatment. Subsequently, he developed gastrointestinal tract lesions. Special stains show positivity for histoplasmosis The case is presented because of its resemblance to tuberculosis. How to cite this article Chaganti PD, Prabhakar YVS, Seetaram KA, Babu K. Caseating Granulomatous Inflammation: Think beyond Tuberculosis. Int J Phonosurg Laryngol 2013;3(2):51-54.


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