scholarly journals Add-On Effect of Chinese Herbal Medicine Bath to Phototherapy for Psoriasis Vulgaris: A Systematic Review

2013 ◽  
Vol 2013 ◽  
pp. 1-14 ◽  
Author(s):  
Jason Jingjie Yu ◽  
Claire Shuiqing Zhang ◽  
Anthony Lin Zhang ◽  
Brian May ◽  
Charlie Changli Xue ◽  
...  

Psoriasis vulgaris is the most common form of psoriasis. Phototherapy has been proven effective for psoriasis, but side effects have become a concern. Chinese herbal medicine (CHM) bath combined with phototherapy has been used in clinical settings, but the additional benefit requires evaluation. This review aims to evaluate the additional benefit and safety of adding CHM bath to phototherapy for psoriasis vulgaris. Cochrane library, PubMed, Embase, CNKI, and CQVIP were searched from their inceptions to 6 August 2012. Randomized controlled trials (RCTs) comparing CHM bath plus phototherapy to phototherapy alone for psoriasis vulgaris were included. Data was analyzed using Review Manager 5.1.0. Thirteen RCTs were included in the review, and eight were included in the meta-analysis. Meta-analysis showed higher efficacy of CHM bath plus phototherapy when compared with phototherapy alone in terms of PASI 60 (RR 1.25; 95% CI: 1.18–1.32). Mild adverse events were reported in ten studies, but these could be alleviated by reducing UV dosage or applying emollient. In conclusion, CHM bath appears to be a beneficial and safe adjunctive therapy to phototherapy for psoriasis vulgaris. However, these results should be interpreted with caution due to the low methodological quality of the included studies.

2016 ◽  
Vol 22 (3) ◽  
pp. 174-188 ◽  
Author(s):  
Claire Shuiqing Zhang ◽  
Lihong Yang ◽  
Anthony Lin Zhang ◽  
Brian H. May ◽  
Jason Jingjie Yu ◽  
...  

2021 ◽  
Vol 12 ◽  
Author(s):  
Lei Shen ◽  
Si Ra Gwak ◽  
Zhen Yang Cui ◽  
Jong Cheon Joo ◽  
Soo Jung Park

Background: Cervical cancer is the fourth most common malignant tumor among women worldwide. This study aimed to evaluate the efficacy of Astragalus-containing Chinese herbal medicine (CHM) combined with chemotherapy (CT) for the treatment of cervical cancer.Methods: Ten electronic databases including PubMed, Cochrane Library, Embase, Korean databases, and Chinese medical databases, were systematically searched up to July 2020. All randomized controlled trials using Astragalus-containing CHM combined with CT to treat cervical cancer were included.Results: A total of 19 trials were included in the analysis. Compared with the control group, the Astragalus-containing CHM combined with CT group showed a significantly increased tumor response (complete and partial response (CR and PR)) (risk ratio [RR] = 1.25, 95% confidence interval [CI]: 1.17–1.33, p < 0.00001) and Karnofsky performance score (KPS) (standardized mean difference [SMD] = 1.81, 95% CI: 1.46–2.17, p < 0.00001). This group also displayed remarkably reduced CT toxicity.Conclusion: Our study suggests that Astragalus-containing CHM might be a potential option for cervical cancer to enhance the curative efficacy and reduce CT toxicity.


2016 ◽  
Vol 2016 ◽  
pp. 1-14 ◽  
Author(s):  
Yu-Shuo Zhu ◽  
Yun-Lun Li ◽  
Jian-Qing Ju ◽  
Feng Du ◽  
Yan-Ping Zang ◽  
...  

Dilated cardiomyopathy (DCM) is one of the main causes of heart failure and could increase death, hospitalization, and rehospitalization rate. The effect of conventional medicine treatment (CMT) is limited; meanwhile, the combination of CMT and Oral Chinese Herbal Medicine (OCHM) represents exciting adjunctive therapies. In this study, we ascertained the therapeutic effect of OCHM in combination with CMT for dilated cardiomyopathy by using meta-analysis methods for controlled clinical trials. We searched studies from five databases and extracted data from these studies. We also assessed the methodological quality of the included studies. We evaluated the following outcome measures to estimate the prognosis in patients with DCM: left ventricular ejection fraction (LVEF), left ventricular end-diastolic dimension (LVEDD), stroke volume (SV), brain natriuretic peptide (BNP), 6-minute walk test (6MWT), and overall efficacy. The result showed that OCHM combined with CMT for the improvement of therapeutic effect in DCM patients. However, the evidence remains weak due to the small sample size, high clinical heterogeneity, and poor methodological quality of the included trials. Further, large sample size and well-designed trials are needed.


2020 ◽  
Author(s):  
Shouliang Hu ◽  
Lu Li ◽  
Xin Zhu ◽  
Yijie Fu ◽  
Hui Li ◽  
...  

Abstract Background: In east Asian countries, the traditional treatment is to treat chronic rhinosinusitis(CRS) with some herbal formulas. However, there is a lack of clinical evidence to support the effect of the drug. Here, we describe a randomized controlled trial to investigate the efficacy and safety of herbal formulations for the treatment of CRS.Methods: We will search electronic databases including the Cochrane Central Register of Controlled Trials (CENTRAL), Chinese Biomedical Literature Database (CBM), PubMed, Embase, Chinese Science and Technology Periodical Database (VIP), China National Knowledge Infrastructure (CNKI), and Wanfang database using keywords related to CRS and Chinese herbal medicine. Extensive database search was carried out for CRS related randomized controlled trials.Two reviewers(SH and LL) will independently filter the search results to determine eligible articles, complete data collection.The quality of individual trials will be assessed by(XZ and YF) using the Cochrane collaborative bias risk assessment tool. We will calculate the relative risk and 95% confidence interval(CI) of the dichotomy results and the weighted average difference, as well as the corresponding 95% confidence interval of the continuous results. Statistical methods such as subgroup analysis and sensitivity analysis will be used to investigate the sources of heterogeneity.Discussion: The systematic review and meta-analysis will provide evidence for the quality of life and the safety of traditional Chinese medicine in CRS patients.This study will provide a high quality research method for the therapeutic effect of Chinese herbal medicine on CRS, and will also help broaden research horizons for the complementary and alternative therapy of CRS.Systematic review registrationPROSPERO registration number: CRD42019123047(https://www.crd.york.ac.uk/prospero/display_record.php?ID=CRD42019123047).


2019 ◽  
Vol 18 ◽  
pp. 153473541987281
Author(s):  
Jie Hao ◽  
Xiaoshu Zhu ◽  
Caroline A. Smith ◽  
Alan Bensoussan

Background. Peripheral neurotoxicity caused by oxaliplatin (OXA) chemotherapy is the main limitation preventing continuation of chemotherapy in patients with gastrointestinal cancer. The purpose of this study was to determine the efficacy of external use of Chinese herbal medicine (CHM) on the incidence of cumulative OXA-induced peripheral neurotoxicity (OIPN). Method. Scientific literature databases were searched to identify controlled clinical trials analyzing CHM in OIPN. Clinical studies that included at least 1 relevant primary outcome were analyzed by 2 independent reviewers. Meta-analysis was performed on the software RevMan 5.3. Results. 700 cancer patients of 9 studies were reported, of whom 352 received external CHM and 348 received warm water baths, conventional medicine, or no intervention as controls. Neurotoxicity incidence (Levi grade ≥ 1) was significantly decreased in CHM group, compared with no intervention ( P < .01). The incidence of cumulative neurotoxicity (Levi grade ≥2) was also significantly lower in the CHM group than in all the control groups ( P < .05), and the cumulative neurotoxicity in the CHM group was significantly reduced (Levi grade ≥ 3) in comparision with no intervention ( P < .01). These results were consistent with those of the subgroup analyses for preventing OIPN at each of the chemotherapy treatment cycles. There was no difference in the incidence of adverse events between groups ( P > .05). Conclusion. External use of CHM may be beneficial in preventing the OXA-induced cumulative neurotoxicity. However, given the low quality of the evidence, the results should be interpreted with caution.


2021 ◽  
Author(s):  
Dong Shen ◽  
◽  
Zhuang Xiong ◽  
Yangyang Liu ◽  
Yan Leng ◽  
...  

Review question / Objective: The aim of this systematic review is to valuate the efficacy and safety of acupuncture combined with Chinese herbal medicine in the treatment of primary liver cancer inform clinical practice. To this end, the proposed systematic review will address the following question: Which is the best choice to effective in improving The short-term curative effect is effective, the quality of life is stable, and the survival rate of patients is six months/one year in patients with primary liver cancer, acupuncture combined with Chinese herbal medicine or the best supportive treatment? Information sources: We will search the following databases: PubMed, Web of Science, Embase, AMED, Cochrane Library, CNKI, VIP, CBM, and Wanfang. Additionally, we will manually search all reference lists from relevant systematic reviews to find other eligible studies. We will exclude all conference records, reviews, meta-analyses, newspapers, guides, letters and other documents. When the full text or the required information in the analysis process was missing, the author of the studies was contacted for data.


2021 ◽  
Author(s):  
Dong Shen ◽  
◽  
Zhuang Xiong ◽  
Yangyang Liu ◽  
Yan Leng ◽  
...  

The aim of this systematic review is to compare Chinese herbal medicine combined with Sorafenib in terms of efficacy and acceptability in the primary liver cancer to better inform clinical practice. To this end, the proposed systematic review will address the following question: Which is the best choice to reduce Efficacy and safety in Patients with primary liver cancer, Chinese herbal medicine combined with Sorafenib or Sorafenib.this systematic review and meta-analysis will evaluate the efficacy and Sorafenib combined with Chinese herbal medicine in the treatment of PLC. Information sources: We will search the following databases from inception up to September 8, 2021: PubMed, Web of Science, Embase, AMED, Cochrane Library, CNKI, VIP, CBM, and Wanfang. There will be no restrictions regarding publication date or language. We will apply a combination of medical keywords and words, including "Sorafenib", "Chinese herbal medicine" and "primary liver cancer". Additionally, we will manually search all reference lists from relevant systematic reviews to find other eligible studies.


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