scholarly journals Toxic Anterior Segment Syndrome following Phacoemulsification Secondary to Overdose of Intracameral Gentamicin

2014 ◽  
Vol 2014 ◽  
pp. 1-3 ◽  
Author(s):  
Yaran Koban ◽  
Selim Genc ◽  
Gorkem Bilgin ◽  
Halil Huseyin Cagatay ◽  
Metin Ekinci ◽  
...  
Keyword(s):  
Anterior Chamber ◽  
Corneal Endothelium ◽  
Penetrating Keratoplasty ◽  
Histopathological Examination ◽  
Anterior Segment ◽  
High Dose ◽  
Bullous Keratopathy ◽  
Corneal Incision ◽  
Toxic Anterior Segment Syndrome ◽  
Corneal Button

Objective. To report a case of toxic anterior segment syndrome (TASS) that was caused by inadvertent anterior chamber and cornea stromal injection with high dose gentamicin following cataract surgery.Methods. Case report.Results. We report a 72-year-old female patient who developed TASS that was caused by high dose gentamicin (20 mg/0.5 mL), which was inadvertently used during the formation of the anterior chamber and hydration of the corneal incision. Unlike previous cases, hyphema and hemorrhagic fibrinous reaction were seen in the anterior chamber. Despite treatment, bullous keratopathy developed and penetrating keratoplasty was performed. The excised corneal button was sent for histopathological examination.Conclusions. Subconjunctival gentamicin is highly toxic to the corneal endothelium and anterior chamber structures. Including it on the surgical table carries a potentially serious risk for contamination of the anterior chamber.

scholarly journals Enzymotherapy of toxic anterior segment syndrome after phacoemulsification

2017 ◽  
Vol 10 (2) ◽  
pp. 87-93
Author(s):  
Alexander S Suvorov ◽  
Timur G Sazhin
Keyword(s):  
Visual Acuity ◽  
Anterior Chamber ◽  
Treatment Initiation ◽  
Anterior Segment ◽  
Treatment Result ◽  
Eye Drops ◽  
Group Iii ◽  
Group I ◽  
Toxic Anterior Segment Syndrome ◽  
Observation Period

Purpose. To investigate the efficacy of recombinant prourokinase (RPU) treatment in patients with toxic anterior segment syndrome after phacoemulsification. Material and methods. We observed 123 patients (123 eyes) with toxic anterior segment syndrome after phacoemulsification; patients of the group I (n = 30) received only antiinflammatory treatment; in treatment of patients of the group II (n = 31), instillations of the RPU solution were used, in the group III (n = 31), RPU solution was injected subconjunctivally, in the group IV (n = 31) - RPU solution electrophoresis was used. Treatment result analysis was carried out within 30 days. Results. Initial mean visual acuity in groups was 0.09 ± 0.04; 0.1 ± 0.04; 0.09 ± 0.04; 0.08 ± 0.04, and was virtually the same (p > 0.05). In 24 hours after treatment initiation, mean visual acuity in the group III was higher, than in the others. In three days and up to the end of observation period, the lowest mean visual acuity was noted in the group I (p < 0.05). Anterior chamber assessment showed that beginning from the first 24 hours after treatment initiation, in groups III and IV, fibrin lysis in the anterior chamber was more pronounced, than in groups I and II (p < 0.05); by the end of the observation period, worst indices of anterior chamber state were found in the group I (p < 0.05), in other groups, they were almost identical (p < 0.05). When using RPU, no allergic reaction was noted. Conclusions. RPU use in combined toxic anterior segment syndrome therapy after phacoemulsification allows increasing visual acuity, reducing convalescence time, and reducing the number of laser dissections. It was established that all methods of RPU administration are effective. RPU may be administered as eye drops on an outpatient basis, receiving efficacy similar to other administration methods.

Transvaginal Sonographic Diagnosis of Cataract in a Fetus

1996 ◽  
Vol 6 (1) ◽  
pp. 90-93 ◽  
Author(s):  
M. Rosner ◽  
M. Bronshtein ◽  
P. Leikomovitz ◽  
M. Berkenstat ◽  
G. Barkai ◽  
...  
Keyword(s):  
Light Microscopy ◽  
Anterior Chamber ◽  
Histopathological Examination ◽  
Anterior Segment ◽  
New Technique ◽  
Transvaginal Sonography ◽  
Serial Sections ◽  
Sonographic Diagnosis ◽  
Normal Gestation ◽  
Retinal Dysplasia

Transvaginal ultrasonography is a relatively new technique for visualizing the orbits in a fetus of 4 to 5 cm. At fifteen weeks of gestation it is possible to recognize the lenses and the hyaloid arteries in the eyes, to diagnose structural malformations such as anophthalmos, microphthalmos, buphthalmos and moderate to severe cataract. In most cases cataracts were associated with intracranial defects. We describe a case where the sonographic diagnosis of fetal cataract was confirmed by histopathological examination. A 27-year-old woman had a routine transvaginal sonography at 15 weeks’ normal gestation. Microphthalmos without a hyaloid artery and disorganization of the anterior chamber and lens consistent with cataract were demonstrated in the fetal left eye. In accordance with the parents’ decision, the pregnancy was terminated a week later. Autopsy of the fetus was done and serial sections of the left eye were studied by light microscopy. Histopathological examination verified the sonographic diagnosis of fetal cataract in a microphthalmic eye. Associated findings included malformation of the anterior segment and retinal dysplasia.

The effect of mydriasis on moderate-to-high myopic eyes with implantable collamer lenses V4 and V4c

2019 ◽  
Vol 30 (3) ◽  
pp. 462-468 ◽  
Author(s):  
Yi Zhu ◽  
Jing Zhang ◽  
Haobin Zhu ◽  
Jili Chen ◽  
Jibo Zhou
Keyword(s):  
Observational Study ◽  
Anterior Chamber ◽  
Corneal Endothelium ◽  
Anterior Segment ◽  
Anterior Chamber Depth ◽  
Central Hole ◽  
Pressure Equilibrium ◽  
Before And After ◽  
Icl V4c

Purpose:To evaluate the vault change and anterior segment movement induced by mydriasis in moderate-to-high myopic eyes with implantable collamer lenses (ICL).Setting:Shanghai, ChinaDesign:A prospective consecutive observational study.Methods:A total of 45 eyes of 24 patients with ICL V4 implantation and 128 eyes of 65 patients with ICL V4c implantation were included and analyzed. Anterior chamber depth, posterior corneal endothelium-to-ICL distance, and vault before and after mydriasis were measured by Pentacam (Oculus, Wetzlar, Germany) at 1, 3, and 6 months after surgery.Results:Significant vault increases and anterior chamber depth increases induced by mydriasis were noted in both ICL V4 and V4c groups at 1, 3, and 6 months postoperatively. The corneal endothelium-ICL distance increased significantly in eyes with implanted ICL V4c after mydriasis at 3 and 6 months. Moreover, mydriasis-induced vault increases were greater in the ICL V4 group than in the ICL V4c group at 3 and 6 months. In eyes with implanted ICL V4c, mydriasis-induced vault increases were significantly greater at 1 month than at 3 and 6 months.Conclusion:Mydriasis results in a general vault increase in eyes with implanted ICLs. The adjustment of the pressure equilibrium via the central hole of the ICL V4c has an important role in vault change. The mydriasis-induced vault increases tend toward stability after 3 months postoperatively. Mydriasis is relatively safe in eyes with ICL implantation.

Toxic anterior segment syndrome and possible association with ointment in the anterior chamber following cataract surgery

2006 ◽  
Vol 32 (2) ◽  
pp. 227-235 ◽  
Author(s):  
Liliana Werner ◽  
Jeffrey H. Sher ◽  
Joel R. Taylor ◽  
Nick Mamalis ◽  
Wesley A. Nash ◽  
...  
Keyword(s):  
Cataract Surgery ◽  
Anterior Chamber ◽  
Anterior Segment ◽  
Toxic Anterior Segment Syndrome

scholarly journals Exophiala Keratitis following Descemet Stripping Automated Endothelial Keratoplasty

2020 ◽  
Vol 2020 ◽  
pp. 1-3
Author(s):  
Ana Marta ◽  
Paula Costa ◽  
Virgínia Lopes ◽  
Miguel Mesquita Neves ◽  
Miguel Gomes ◽  
...  
Keyword(s):  
Anterior Segment ◽  
Fungal Keratitis ◽  
Bullous Keratopathy ◽  
Endothelial Keratoplasty ◽  
Slit Lamp ◽  
Direct Examination ◽  
First Case ◽  
Pseudophakic Bullous Keratopathy ◽  
Positive Direct ◽  
Corneal Button

Purpose. To report a case with Exophiala spp. keratitis in a Portuguese patient. Methods. A case report with deep corneal brown-pigmented infiltrates that developed 2 months after a Descemet Stripping Automated Endothelial Keratoplasty (DSAEK) for pseudophakic bullous keratopathy. Results. Diagnosis was established by positive direct examination and cultures from the surgically obtained corneal button. Slit-lamp images and anterior segment optical coherence tomography (AS-OCT) scans were obtained. Conclusion. This is the first described case of fungal keratitis caused by Exophiala spp. in Portugal and, to our knowledge, the first case following DSAEK in the literature.

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