scholarly journals Microvascular Complications and Their Associated Risk Factors in Newly Diagnosed Type 2 Diabetes Mellitus Patients

2014 ◽  
Vol 2014 ◽  
pp. 1-7 ◽  
Author(s):  
Dipika Bansal ◽  
Kapil Gudala ◽  
Hari Prasad Esam ◽  
Ramya Nayakallu ◽  
Raja Vikram Vyamusani ◽  
...  

The study was aimed at assessing the prevalence of microvascular complications and associated risk factors in newly diagnosed type 2 diabetes mellitus patients. A cross-sectional study was conducted in a public tertiary care hospital. All the recruited patients underwent extensive examination for the presence of microvascular complications like neuropathy, retinopathy, and nephropathy. Prevalence of any complication was 18.04%. Prevalence of neuropathy, retinopathy, and nephropathy was found to be 8.2%, 9.5%, and 2.8%, respectively. Triglycerides (OR, 1.01;P = 0.011) and old age (OR, 1.06;P ≤0.01) were significantly associated with any complication. Triglycerides were significantly associated with neuropathy (OR, 1.01;P = 0.05) and retinopathy (OR, 1.01;P =0.02). Being male posed high risk for nephropathy (OR, 0.06;P =0.01). These results are suggesting need of regular screening for microvascular complications.

2017 ◽  
Vol 11 ◽  
pp. S577-S581 ◽  
Author(s):  
Parvin Akter Khanam ◽  
Sayama Hoque ◽  
Tanjima Begum ◽  
Samira Humaira Habib ◽  
Zafar Ahmed Latif

2021 ◽  
Vol 1 (12) ◽  
pp. e0000003
Author(s):  
Md. Saad Ahmmed ◽  
Suvasish Das Shuvo ◽  
Dipak Kumar Paul ◽  
M. R. Karim ◽  
Md. Kamruzzaman ◽  
...  

Dyslipidemia is considered a significant modifiable risk factor for type-2 diabetes mellitus (T2DM) and has become one of the emerging health problems throughout the world. In Bangladesh, data on dyslipidemia among newly diagnosed T2DM patients are comparatively inadequate. This study aimed to evaluate the prevalence of dyslipidemia and its associated risk factors in newly diagnosed T2DM patients. This cross-sectional study was conducted by a well-structured questionnaire from 132 newly diagnosed type-2 diabetic patients attending the Mujibur Rahman Memorial Diabetic Hospital in Kushtia, Bangladesh. Data regarding socio-demographic, anthropometric, fasting blood glucose, total cholesterol (TC), triglyceride (TG), high-density lipoprotein (HDL), and low-density lipoprotein (LDL) were collected from all the respondents. The association between dyslipidemia and its associated factors was analyzed using the multivariate logit regression model. The findings suggest that the prevalence rate of dyslipidemia was 75.7% in female and 72.6% in male T2DM patients. The odds of having dyslipidemia were 1.74 (95% Cl: 1.58–1.87) times significantly higher in female (p<0.001). The other factors associated with dyslipidemia encompassed age between 30–39 years (OR: 2.32, 95% CI: 1.97–2.69), obesity (OR: 2.63, 95% CI: 2.27–2.90), waist circumferences of male ≥90 and female ≥80 (OR: 1.65, 95% CI: 1.59–1.89), hypertensive patients (OR: 1.51, 95% CI: 1.45–1.74), physically inactive (OR: 3.25, 95% CI: 1.84–4.68), and current smoker or tobacco user (OR: 1.93, 95% CI: 1.85–2.13). This study concluded that the high prevalence of dyslipidemia was found among newly diagnosed type-2 diabetes patients and associated with gender, age, BMI, waist circumference, poor physical activity, and smoking, or tobacco use. This result will support increase awareness of dyslipidemia and its associated risk factors among type-2 diabetes patients.


2013 ◽  
Vol 29 (2) ◽  
Author(s):  
Sadiq Hussain ◽  
Muhammad Rashad Qamar ◽  
Muhammad Arshad Iqbal ◽  
Ameer Ahmed ◽  
Ehsan Ullah

2020 ◽  
pp. 75-77
Author(s):  
Satish Desai ◽  
Priyanka A. Mahendrakar

AIM: To estimate the frequency of Diabetic Retinopathy and the possible risk factors associated with Diabetic Retinopathy. MATERIALS AND METHODS: All patients of diagnosed type 2 Diabetes Mellitus attending Ophthalmology Outpatient Department in Government Medical College and Hospital, Miraj during the study period were included. History was taken and a complete ophthalmic examination was done. Diabetic Retinopathy was graded according to ETDRS classification. Data was analyzed using SPSS 22 version software. RESULT: A total of 275 patients with diagnosed Diabetes Mellitus were examined. Frequency of diabetic retinopathy in the study was 30.91%. Significant association was found with male gender (p=0.008), duration of Diabetes Mellitus more than 10 years (p<0.001), positive family history (p<0.001), use of insulin (p<0.001), raised systolic and diastolic blood pressure (p<0.001), fasting and post prandial blood sugar levels (p<0.001). Age, smoking status and body mass index were not found to be significant risk factors for the development of diabetic retinopathy.


Author(s):  
Yashaswini P. ◽  
Geetha A. ◽  
Ravi K.

Background: Oxidative stress plays major role in diabetes mellitus (DM), abnormal high free radicals decline antioxidant defence mechanism can lead to damage of cellular organelles and enzymes, increased lipid peroxidation and insulin resistance leads to development of complications. Supplementation of antioxidants protects free radical induced damage and further complications. The objective was to evaluate the efficacy and safety of metformin versus metformin with vitamin C and E on glycaemic parameters in newly diagnosed type 2 diabetes mellitus (T2DM).Methods: 60 newly diagnosed T2DM patients were randomized into two groups of 30 in each to receive metformin (500 mg BD) alone in group A versus metformin (500 mg BD)+vitamin C (500 mg OD)+vitamin E (400 mg OD) in group B for 12 weeks. Efficacy was measured by improvement in glycaemic (FBS fasting blood sugar, PPBS postprandial blood sugar and HbA1c glycosylated haemoglobin) parameters at week 4, 8 and 12 from baseline. Safety was assessed by monitoring treatment emergent adverse effects.Results: The baseline characteristics were comparable between the two groups. There was a significant reduction of glycaemic parameters seen in both the groups from baseline to week 12 (p<0.001) but the difference was not statistically significant between the two groups (p>0.05). No significant adverse effects were noted.Conclusions: Both the groups are effective in improving glycaemic indices and supplementation of vitamins along with metformin as compared to metformin alone with no significant adverse effect. Hence, daily consumption of vitamins may be beneficial in decreasing blood glucose in patients with T2DM and thus reducing the risk of complications.


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