scholarly journals Considering Patients’ Mental Capacity When Giving Them Bad News May Help Their Well-Being: A Case of Suicide Attempt after Being Informed of Lung Cancer Diagnosis

2014 ◽  
Vol 2014 ◽  
pp. 1-4
Author(s):  
Toshiyuki Kobayashi ◽  
Satoshi Kato ◽  
Mitsuo Takeuchi
Keyword(s):  
Lung Cancer ◽  
Suicide Attempt ◽  
Cancer Diagnosis ◽  
Attempted Suicide ◽  
Well Being ◽  
Mental Capacity ◽  
Bad News ◽  
Lung Cancer Diagnosis ◽  
Diagnosis Of Lung Cancer ◽  
Mental Well Being

Mental capacity is a central determinant of patients’ ability to make autonomous decisions about their care and deal with bad news. Physicians should be cognizant of this when giving patients bad news in efforts to help them to cope with the illness and to avoid a deterioration of their mental well-being. To show the importance of this concept, a case of suicide attempt with lung cancer is exemplified. A 76-year-old woman attempted suicide after receiving a diagnosis of lung cancer. Her recent life had been emotionally turbulent and she did not have sufficient mental capacity to accept and cope with this truth. She developed depression before attempting suicide.

scholarly journals Challenges in lung cancer diagnosis during the outbreak of COVID-19

2020 ◽  
Author(s):  
chunhua xu ◽  
wei wang ◽  
li li ◽  
jiwang wang
Keyword(s):  
Lung Cancer ◽  
Cancer Diagnosis ◽  
Needle Biopsy ◽  
Transbronchial Biopsy ◽  
Public Health Emergency ◽  
Lung Cancer Patients ◽  
Lung Cancer Diagnosis ◽  
Diagnosis Of Lung Cancer ◽  
Novel Coronavirus ◽  
Individualized Management

A pandemic of 2019 novel coronavirus diseases (COVID-19) outbreak is a major public health emergency that has spread in the fastest speed, and caused the most extensive infection world widely. Transbronchial biopsy (TBB) and computed tomography guided percutaneous needle biopsy (CTPNB) is the most common and significant method for the diagnosis of lung cancer. During the COVID-19 pandemic, the indications of TBB and CTPNB must be managed strictly. Therefore, it is extremely indispensable to perform meticulous and individualized management for lung cancer patients to protect the patients from COVID-19.

scholarly journals Ancillary Testing in Lung Cancer Diagnosis

2012 ◽  
Vol 2012 ◽  
pp. 1-8 ◽  
Author(s):  
William Dubinski ◽  
Natasha B. Leighl ◽  
Ming-Sound Tsao ◽  
David M. Hwang
Keyword(s):  
Lung Cancer ◽  
Molecular Diagnostics ◽  
Cancer Diagnosis ◽  
Targeted Therapies ◽  
Patient Management ◽  
Predictive Information ◽  
Lung Cancers ◽  
Pathologic Diagnosis ◽  
Lung Cancer Diagnosis ◽  
Diagnosis Of Lung Cancer

The pathologic diagnosis of lung cancer historically has relied primarily on morphologic features of tumors in histologic sections. With the emergence of new targeted therapies, the pathologist is called upon increasingly to provide not only accurate typing of lung cancers, but also to provide prognostic and predictive information, based on a growing number of ancillary tests, that may have significant impact on patient management. This review provides an overview of ancillary tests currently used in the pathologic diagnosis of lung cancer, with a focus on immunohistochemistry and molecular diagnostics.

scholarly journals Effect of Comorbidity on Lung Cancer Diagnosis Timing and Mortality: A Nationwide Population-Based Cohort Study in Taiwan

2018 ◽  
Vol 2018 ◽  
pp. 1-9 ◽  
Author(s):  
Shinechimeg Dima ◽  
Kun-Huang Chen ◽  
Kung-Jeng Wang ◽  
Kung-Min Wang ◽  
Nai-Chia Teng
Keyword(s):  
Lung Cancer ◽  
Overall Survival ◽  
Cancer Patients ◽  
Cancer Diagnosis ◽  
Population Based ◽  
Physician Visits ◽  
Lung Cancer Patients ◽  
Lung Cancer Diagnosis ◽  
Kaplan Meier ◽  
Diagnosis Of Lung Cancer

The effect of comorbidity on lung cancer patients’ survival has been widely reported. The aim of this study was to investigate the effects of comorbidity on the establishment of the diagnosis of lung cancer and survival in lung cancer patients in Taiwan by using a nationwide population-based study design. This study collected various comorbidity patients and analyzed data regarding the lung cancer diagnosis and survival during a 16-year follow-up period (1995–2010). In total, 101,776 lung cancer patients were included, comprising 44,770 with and 57,006 without comorbidity. The Kaplan–Meier analyses were used to compare overall survival between lung cancer patients with and without comorbidity. In our cohort, chronic bronchitis patients who developed lung cancer had the lowest overall survival in one (45%), five (28.6%), and ten years (26.2%) since lung cancer diagnosis. Among lung cancer patients with nonpulmonary comorbidities, patients with hypertension had the lowest overall survival in one (47.9%), five (30.5%), and ten (28.2%) years since lung cancer diagnosis. In 2010, patients with and without comorbidity had 14.86 and 9.31 clinical visits, respectively. Lung cancer patients with preexisting comorbidity had higher frequency of physician visits. The presence of comorbid conditions was associated with early diagnosis of lung cancer.

scholarly journals Cryobiopsy in Lung Cancer Diagnosis—A Literature Review

Medicina ◽  
2021 ◽  
Vol 57 (4) ◽  
pp. 393
Author(s):  
Mărioara Simon ◽  
Ioan Simon ◽  
Paul Andrei Tent ◽  
Doina Adina Todea ◽  
Antonia Haranguș
Keyword(s):  
Lung Cancer ◽  
Cancer Diagnosis ◽  
Diagnostic Yield ◽  
Lung Tumors ◽  
Small Sample ◽  
Diagnostic Methods ◽  
Endobronchial Ultrasound ◽  
Forceps Biopsy ◽  
Lung Cancer Diagnosis ◽  
Diagnosis Of Lung Cancer

Optimizing the diagnosis of lung cancer represents a challenge, as well as a necessity, for improving the low survival of these patients. Flexible bronchoscopy with forceps biopsy is one of the key diagnostic procedures used for lung tumors. The small sample size and crush artifacts are several factors that can often limit access to a complete diagnosis, therefore leading to the need of repeating the bronchoscopy procedure or other invasive diagnostic methods. The bronchoscopic cryobiopsy is a recent technique that proved its utility in the diagnosis of both endobronchial and peripheral lung tumors. In comparison with conventional forceps biopsy, studies report a higher diagnostic yield and a superior quality of the collected samples for both the histopathological and the molecular diagnosis of lung cancer. This method shows promising results in sampling lung tissue, alone, or in conjunction with fluoroscopy or radial endobronchial ultrasound (r-EBUS). With a good safety and cost-benefit profile, this novel method has the potential to improve the diagnosis, and therefore the management of lung cancer patients. The objective of this narrative review is to provide a comprehensive review of the recent data regarding the advantages of cryobiopsy and r-EBUS in lung cancer diagnosis.

scholarly journals Diagnostic efficacy cell block method of transthoracic fine needle aspiration in diagnosis of lung cancer

2021 ◽  
Vol 40 (2) ◽  
pp. 133-140
Author(s):  
Yusup Subagio Sutanto ◽  
Nur Santi ◽  
Brian Wasita ◽  
Ana Rima ◽  
Hendra Kurniawan
Keyword(s):  
Lung Cancer ◽  
Sensitivity And Specificity ◽  
Cancer Diagnosis ◽  
Fine Needle Aspiration ◽  
Needle Aspiration ◽  
Cell Block ◽  
Fine Needle ◽  
Lung Cancer Diagnosis ◽  
Bronchial Washing ◽  
Diagnosis Of Lung Cancer

BackgroundLung cancer is still the main cause of cancer deaths. The high lung cancer mortality rate is caused by a diagnosis factor or therapy selection. The cell block cytology technique using fine needle aspiration (FNA) samples can provide immunocytochemical material that plays an important role in the differential diagnosis of lung cancer subtypes and in determining immunotherapy administration. This study aimed to determine the sensitivity and specificity of transthoracic FNA (TTFNA) cell block cytology in comparison with bronchial washing smears and TTFNA smears in diagnosing lung cancer. MethodsThis was a cross-sectional diagnostic study involving 26 subjects. All subjects had undergone bronchial washing and CT scan-guided fine needle aspiration followed by cell block preparation. Both direct FNA smears and cell blocks are useful in the diagnostic work-up of patients. Comparative statistical analysis of TTFNA cell block versus bronchial washing smear and TTFNA smear cytology was carried out using the McNemar test. ResultsLung cancer was found in 15 patients (57.7%) using the TTFNA cell block technique. The sensitivity and specificity of the TTFNA cell block technique were 85.7% and 75%, respectively. There was no difference in the positivity value between TTFNA cell block technique of bronchial wash smear technique, and TTFNA smear on lung cancer diagnosis (p>0.05). ConclusionsTransthoracic fine-needle aspiration in combination with the cell block technique has good sensitivity and specificity. The TTFNA can be used for immunocytochemical examinations in lung cancer diagnosis and therapy. This approach is valuable for providing individualized treatment and prognostic evaluations.

102 Sharing Bad News: Understanding the communication processes of a lung cancer diagnosis

Lung Cancer ◽  
2014 ◽  
Vol 83 ◽  
pp. S38
Author(s):  
N.B. Ngwenya ◽  
M. Farquhar ◽  
J. Benson ◽  
D. Gilligan ◽  
S. Bailey ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Cancer Diagnosis ◽  
Bad News ◽  
Lung Cancer Diagnosis ◽  
Communication Processes

scholarly journals Cytological and histological diagnosis of lung cancer in Sardinia and Italy in the 1990s

2016 ◽  
Vol 67 (4) ◽  
Author(s):  
P. Pirina ◽  
M. Budroni ◽  
S. Esposito ◽  
S. Ostera ◽  
M.F. Polo ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Cancer Patients ◽  
Cancer Diagnosis ◽  
Cancer Registries ◽  
Histological Diagnosis ◽  
Cytological Diagnosis ◽  
Lung Cancer Patients ◽  
Lung Cancer Diagnosis ◽  
Diagnosis Of Lung Cancer

Background. Up to 30-50% of all lung cancer cases remain without cyto-histological characterisation. The aim of our study was to evaluate retrospectively the proportion of histological and/or cytological diagnosis in patients with lung cancer in Sardinia. Methods. Data was gathered by consulting the hospital registers and case notes of individual patients released from hospital with a diagnosis of Lung Cancer at all medical centres throughout Sardinia. In gathering patients’ data, we focused our attention on cytological and histological procedures through which allowed the lung cancer was diagnosed. Cancer Registries data was utilised to compare our data with national and Sassari province data. Results. From 1991 to 1996 there was a total of 3146 lung cancer patients registered in Sardinia. 1902 patients (60.5%) had a histological diagnosis, 142 patients (4.5%) a cytological diagnosis while in 1102 patients (35%) the diagnosis was performed without any pathological validation. Conclusions. Our study has shown that lung cancer diagnosis is supported by pathological verification in 65% of cases while in remaining 35% of patients the diagnosis is based only on clinical and radiological reports. In Italy data from Cancer Registries report the percentage of cyto- histological diagnosis to be 70% with the percentage of cytological diagnosis being higher than in Sardinia.

scholarly journals Challenges in Advanced Lung Cancer Diagnosis During the COVID-19 Pandemic

2021 ◽  
Vol 20 ◽  
pp. 153303382110507
Author(s):  
Chunhua Xu ◽  
Li Li ◽  
Wei Wang
Keyword(s):  
Lung Cancer ◽  
Cancer Diagnosis ◽  
Needle Biopsy ◽  
Transbronchial Biopsy ◽  
Public Health Emergency ◽  
Advanced Lung Cancer ◽  
Lung Cancer Patients ◽  
Lung Cancer Diagnosis ◽  
Diagnosis Of Lung Cancer ◽  
Individualized Management

A pandemic of coronavirus diseases 2019 (COVID-19) outbreak is a major public health emergency that has spread in the fastest speed, and caused the most extensive infection world widely. Transbronchial biopsy (TBB) and computed tomography guided percutaneous needle biopsy (CTPNB) is the most common and significant method for the diagnosis of lung cancer. During the COVID-19 pandemic, the indications of TBB and CTPNB must be managed strictly. Therefore, it is extremely indispensable to perform meticulous and individualized management for lung cancer patients to protect the patients from COVID-19.

scholarly journals Genetic Markers in Lung Cancer Diagnosis: A Review

2020 ◽  
Vol 21 (13) ◽  
pp. 4569 ◽  
Author(s):  
Katarzyna Wadowska ◽  
Iwona Bil-Lula ◽  
Łukasz Trembecki ◽  
Mariola Śliwińska-Mossoń
Keyword(s):  
Lung Cancer ◽  
Genetic Markers ◽  
Cancer Diagnosis ◽  
Early Stage ◽  
Expression Profiles ◽  
Genetic Diagnostics ◽  
Diagnostic Tools ◽  
Lung Cancer Diagnosis ◽  
Diagnostic Potential ◽  
Diagnosis Of Lung Cancer

Lung cancer is the most often diagnosed cancer in the world and the most frequent cause of cancer death. The prognosis for lung cancer is relatively poor and 75% of patients are diagnosed at its advanced stage. The currently used diagnostic tools are not sensitive enough and do not enable diagnosis at the early stage of the disease. Therefore, searching for new methods of early and accurate diagnosis of lung cancer is crucial for its effective treatment. Lung cancer is the result of multistage carcinogenesis with gradually increasing genetic and epigenetic changes. Screening for the characteristic genetic markers could enable the diagnosis of lung cancer at its early stage. The aim of this review was the summarization of both the preclinical and clinical approaches in the genetic diagnostics of lung cancer. The advancement of molecular strategies and analytic platforms makes it possible to analyze the genome changes leading to cancer development—i.e., the potential biomarkers of lung cancer. In the reviewed studies, the diagnostic values of microsatellite changes, DNA hypermethylation, and p53 and KRAS gene mutations, as well as microRNAs expression, have been analyzed as potential genetic markers. It seems that microRNAs and their expression profiles have the greatest diagnostic potential value in lung cancer diagnosis, but their quantification requires standardization.

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