scholarly journals Empyema Caused byClostridium bifermentans: A Case Report

2015 ◽  
Vol 26 (2) ◽  
pp. 105-107 ◽  
Author(s):  
Safa Edagiz ◽  
Phil Lagace-Wiens ◽  
John Embil ◽  
James Karlowsky ◽  
Andrew Walkty
Keyword(s):  
Case Report ◽  
Soft Tissue ◽  
Septic Arthritis ◽  
Brain Abscess ◽  
Soft Tissue Infection ◽  
Tissue Infection ◽  
Gram Positive ◽  
The Third ◽  
Clostridium Bifermentans ◽  
Abdominal Infections

A case of pneumonia with associated empyema caused byClostridium bifermentansis described.C bifermentansis an anaerobic, spore-forming, Gram-positive bacillus. This organism is infrequently reported as a cause of infection in humans, and older publications tended to regard it as nonpathogenic. However, in more recent reports,C bifermentanshas been documented as a cause of septic arthritis, osteomyelitis, soft tissue infection, abdominal infections, brain abscess, bacteremia and endocarditis. The present case is the third reported case of empyema caused byC bifermentans,and it serves to further define the spectrum of illness due to this uncommon organism.

scholarly journals Real-world experience with dalbavancin therapy in gram-positive skin and soft tissue infection, bone and joint infection

Infection ◽  
2019 ◽  
Vol 47 (6) ◽  
pp. 1013-1020 ◽  
Author(s):  
Selma Tobudic ◽  
Christina Forstner ◽  
Heinz Burgmann ◽  
Heimo Lagler ◽  
Christoph Steininger ◽  
...  
Keyword(s):  
Soft Tissue ◽  
Antibiotic Therapy ◽  
Septic Arthritis ◽  
Clinical Improvement ◽  
Soft Tissue Infection ◽  
Joint Infection ◽  
Tissue Infection ◽  
Oral Drug ◽  
Gram Positive ◽  
Positive Skin

Abstract Purpose Dalbavancin is a novel lipoglycopeptide with potent activity against several gram-positive pathogens, an excellent safety profile and a long elimination half-life. Methods In this case series observed at the University Hospital of Vienna between 2015 and 2017, all adult patients with gram-positive infections who received at least one dosage of dalbavancin were screened (n = 118). A total of 72 patients were included in the final analysis. The number of included patients stratified by the source of infection was: skin and soft tissue infection (SSTI) (n = 26), osteomyelitis (n = 20), spondylodiscitis (n = 14), acute septic arthritis (n = 4) and prosthetic joint infection (n = 8). Results In 46 patients (64%), clinical cure was detected at the end of dalbavancin therapy without additional antibiotic therapy. Of the 26 patients who received additional antibiotic therapy other than dalbavancin, 15 patients (21%) showed no clinical improvement under dalbavancin therapy, four patients (5%) had side effects (nausea n = 1, exanthema n = 2, hyperglycemia n = 1), and in seven patients (10%) clinical improvement under dalbavancin therapy was detected but antibiotic therapy was de-escalated to an oral drug. Conclusion We demonstrated high clinical effectiveness of dalbavancin for acute gram-positive infections primarily acute SSTI, acute septic arthritis, acute osteomyelitis and spondylodiscitis. In patients with biofilm-associated infection (chronic infection or joint prosthesis), source control was absolutely necessary for treatment success.

scholarly journals Scedosporium apiospermumcatheter-related soft-tissue infection: a case report and review of the literature

2012 ◽  
Vol 50 (6) ◽  
pp. 627-630 ◽  
Author(s):  
Carole Eldin ◽  
Laurent Chiche ◽  
Guillemette Thomas ◽  
Marie Pierre Dicostanzo ◽  
Jean Marc Durand ◽  
...  
Keyword(s):  
Case Report ◽  
Soft Tissue ◽  
Soft Tissue Infection ◽  
Tissue Infection ◽  
Review Of The Literature

scholarly journals Correction to: Real‑world experience with dalbavancin therapy in gram‑positive skin and soft tissue infection, bone and joint infection

Infection ◽  
2019 ◽  
Vol 48 (1) ◽  
pp. 149-149
Author(s):  
Selma Tobudic ◽  
Christina Forstner ◽  
Heinz Burgmann ◽  
Heimo Lagler ◽  
Christoph Steininger ◽  
...  
Keyword(s):  
Soft Tissue ◽  
Soft Tissue Infection ◽  
Real World ◽  
Joint Infection ◽  
Tissue Infection ◽  
Original Version ◽  
Gram Positive ◽  
Positive Skin ◽  
Bone And Joint Infection ◽  
Corrected Figure

The original version of this article unfortunately contained a mistake. The presentation of Fig. 1 was incorrect. The corrected figure is given below.

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