scholarly journals Underscreened Women Remain Overrepresented in the Pool of Cervical Cancer Cases in Spain: A Need to Rethink the Screening Interventions

2015 ◽  
Vol 2015 ◽  
pp. 1-9 ◽  
Author(s):  
Raquel Ibáñez ◽  
María Alejo ◽  
Neus Combalia ◽  
Xavier Tarroch ◽  
Josefina Autonell ◽  
...  
Keyword(s):  
Cervical Cancer ◽  
Older Women ◽  
Cancer Diagnosis ◽  
Invasive Cervical Cancer ◽  
Previous History ◽  
Figo Stage ◽  
Normal Cytology ◽  
Highly Sensitive ◽  
History Of ◽  
Screening History

Objective. Audit of women with invasive cervical cancer (CC) is critical for quality control within screening activities. We analysed the screening history in the 10 years preceding the study entry in women with and without CC during 2000–2011.Methods. 323 women with CC from six pathology departments in Catalonia (Spain) and 23,782 women with negative cytology were compared. Age, previous history of cytologies, and histological type and FIGO stage were collected from the pathology registries. Logistic regression analysis was used to estimate odds ratios (OR) and 95% confidence intervals (CI95%).Results. History of cytology was registered in 26.2% of CC cases and in 78% of the control women (P<0.0001) and its frequency decreased with increasing age. Compared to women with squamous cell carcinoma, adenocarcinoma cases were significantly more likely to have a cytology within the 3-year interval preceding cancer diagnosis (OR=2.6CI 95%: 1.2–5.6) and to have normal cytology results in previous screenings (OR=2.4CI 95%: 1.2–4.5). FIGO II–IV cases were more common among older women (older than 60 years).Conclusions. Absence of prior screening history was extremely common among CC cases compared to controls. Organized actions to reduce underscreened women and use of highly sensitive HPV-based tests could be important to reduce CC burden.

Screening history of women with invasive cervical cancer in north-east Italy

2010 ◽  
Vol 152 (2) ◽  
pp. 200-204 ◽  
Author(s):  
Antonella Zucchetto ◽  
Silvia Franceschi ◽  
Elena Clagnan ◽  
Diego Serraino ◽  
Loris Zanier ◽  
...  
Keyword(s):  
Cervical Cancer ◽  
Invasive Cervical Cancer ◽  
North East ◽  
History Of ◽  
Screening History

scholarly journals A study on cervical cancer screening using pap smear in urban area in state of Meghalaya, India

2018 ◽  
Vol 7 (8) ◽  
pp. 3113
Author(s):  
Priti Mishra ◽  
Ragini Thapa ◽  
Arvind Kumar Dinkar
Keyword(s):  
Cervical Cancer ◽  
Pap Smear ◽  
Invasive Cervical Cancer ◽  
Pap Test ◽  
Military Hospital ◽  
Normal Cytology ◽  
Pap Smear Test ◽  
Common Cancer ◽  
Bethesda System ◽  
Preinvasive Lesion

Background: Cancer cervix is fourth most common cancer in world second most common in India. The objective of the study is to identify abnormal pap smear cytology in women undergoing the test.Methods: This retrospective study conducted in 200 women attending gynae OPD of Military Hospital, Shillong, Meghalaya, India between January 2016 to December 2017. Pap smear test was done, and classification was done as per Bethesda system 2014.Results: 105 women had normal cytology findings and 23 had abnormal cytology.Conclusions: Cervical cancer is the most common cancer for which screening is done. If pap smear is done every 3 years as per the guidelines mortality due to cervical cancer can be reduced. Every woman should undergo pap test at least once in her life before the age of 45 years. Timely screening of preinvasive lesion allows prevention from invasive cervical cancer.

Presentation and Screening History of Indigent Women with Cervical Cancer: Implications for Prevention

2000 ◽  
Vol 4 (4) ◽  
pp. 208-211 ◽  
Author(s):  
Stewart L. Massad ◽  
Helen E. Cejtin ◽  
Nadeem R. Abu-Rustum
Keyword(s):  
Cervical Cancer ◽  
History Of ◽  
Screening History

scholarly journals Treatment of cervical cancer in the Republic of Srpska

2011 ◽  
Vol 64 (11-12) ◽  
pp. 588-591 ◽  
Author(s):  
Nenad Lucic ◽  
Zora Antonic ◽  
Vesna Ecim ◽  
Dragica Draganovic ◽  
Ljiljana Latinovic
Keyword(s):  
Cervical Cancer ◽  
Postoperative Complications ◽  
Radical Hysterectomy ◽  
Invasive Cervical Cancer ◽  
Figo Stage ◽  
International Federation ◽  
Gynecology And Obstetrics ◽  
The Republic ◽  
Banja Luka ◽  
Cervical Tumors

Introduction. Since 1897, when the first radical hysterectomy with lymphadenectomy was done by Wertheim in Vienna, this operation has had the central role in the surgical treatment of invasive cervical tumors. Material and methods. In the period from 1997 to 2010, 177 patients diagnosed with invasive cervical cancer according to the International Federation of Gynecology and Obstetrics (FIGO) stage IB1 - II were operated at the Department of Obstetrics and Gynecology in Banja Luka. All patients underwent radical hysterectomy by Wertheim - Meigs. The aim of this study is to present the technique of this operation, as well as its effectiveness in the treatment of cervical cancer. Results. The distribution of the patients having invasive cervical cancer according to the International Federation of Gynecology and Obstetrics classification was as follows: I B1 - 35.67%, I B2 - 23.17%, II A - 15.48%, II B - 25.68% on average is 21.3 removed lymph glands. The rate of intraoperative and postoperative complications was 8 (4.51%) and 17 (9.60%), respectively. Of the 26 patients who were operated in the period from 2005 - 2010, 13 had stage II B according to the International Federation of Gynecology and Obstetrics; there were 6 lethal outcomes (23.08) and the five-year survival rate was 76.92%. Discussion and conclusion. By applying the proper surgical technique and early prevention of immediate complications, we achieved satisfactory results in operative morbity and mortality, intraoperative and postoperative complications of the lesion for radical surgery by the Wertheim- Meigs-in the treatment of cancer of the uterus in the I B - II B stage according to the International Federation of Gynecology and Obstetrics classification.

scholarly journals Clinical Features of Women Diagnosed With Invasive Cervical Cancer in Ghana

2018 ◽  
Vol 4 (Supplement 2) ◽  
pp. 40s-40s
Author(s):  
Y. Nartey ◽  
P. Hill ◽  
K. Amo-Antwi ◽  
K. Nyarko ◽  
J. Yarney ◽  
...  
Keyword(s):  
Cervical Cancer ◽  
Clinical Features ◽  
Teaching Hospital ◽  
Cervical Screening ◽  
Invasive Cervical Cancer ◽  
Figo Stage ◽  
Middle Income ◽  
Increased Risk ◽  
Referral Hospitals

Background: The incidence of cervical cancer continues to increase in many low- and middle-income countries. It remains the commonest cancer affecting females in Ghana. However, comprehensive information on the clinical characteristics of women diagnosed with invasive cervical cancer is scarce. Aim: To characterize the clinical features of women with invasive cervical cancer in Ghana. Methods: We conducted a retrospective study in two large referral hospitals in Ghana: the Korle Bu teaching hospital, Accra and Komfo Anokye teaching hospital, Kumasi. Through the review of paper-based, electronic, and pathology medical records, information on women diagnosed with invasive cervical cancer from 1st January 2010 to 31st December 2013 was collected. The information was entered onto a standardized data abstraction sheet and included demographics, comorbid conditions, treatment and follow-up. All analyses were conducted in STATA and described the distribution of key clinical features by the stage at diagnosis. Results: A total of 1,725 women with invasive cervical cancer were included in the analysis. Few had cervical screening before their cervical cancer diagnosis (1.1%). Women who were resident in a metropolitan area ( P = 0.034), or who had any comorbidity ( P < 0.001) were at an increased risk of FIGO stage III-IV disease. The majority of women had at least two diagnostic investigations (75%) with cervical biopsy performed for 95.5% of women. More than half received radiotherapy (55.4%) and only 22.4% receiving chemotherapy. Clinical follow-up after the first consultation was performed for 61%, with 73% of women with clinical follow-up having at least one follow-up investigation. Conclusion: Improvements in access to early diagnosis and optimal treatment of cervical cancer, such as an increased use of chemoradiation would reduce the burden of the disease in Ghana.

Persistent opioid use after radiation therapy in opioid-naive cervical cancer survivors

2019 ◽  
Vol 29 (7) ◽  
pp. 1105-1109 ◽  
Author(s):  
Kelsey Ward ◽  
Amin Ramzan ◽  
Jeanelle Sheeder ◽  
Stacy Fischer ◽  
Carolyn Lefkowits
Keyword(s):  
Cervical Cancer ◽  
Substance Abuse ◽  
Cancer Survivors ◽  
Multivariable Analysis ◽  
Figo Stage ◽  
Opioid Use ◽  
Opioid Prescription ◽  
Gynecology And Obstetrics ◽  
History Of ◽  
Disease Free

ObjectivesOpioids are first-line therapy for cancer-related pain, but their use should be minimized in disease-free survivors. We sought to describe rates and identify predictors of persistent opioid use among previously opioid-naive cervical cancer survivors treated with radiation.MethodsOpioid-naive cervical cancer patients treated primarily with radiation and chemosensitization at a single institution, between January 2011 and December 2015, were identified. Charts were reviewed for demographics, disease, and treatment characteristics, and opioid prescriptions. Primary outcome was persistent opioid use, defined as continued opioid prescription use, 6 months after radiation; patients recurring within 6 months were excluded. Groups were compared using χ2 or Fisher’s exact test. Multivariable logistic regression identified predictors of persistent opioid use.ResultsA total of 96 patients were included, with a median age of 49 years (range 27–84). Most patients (59%) at diagnosis had International Federation of Gynecology and Obstetrics (FIGO) stage I or II cervical cancer. The most common histology was squamous cell carcinoma (72%) and most (94.7%) patients received radiation with chemosensitization. Rates of persistent opioid use at 3 and 6 months after treatment were 29% and 25%, respectively. Persistent users were more likely to be <40 years old, have disease outside the pelvis at diagnosis, and have had a history of substance abuse, depression or anxiety (p<0.05). In multivariable analysis, a history of substance abuse (adjusted OR 6.21, 95% CI 1.08 to 35.67) and depression or anxiety (aOR 6.28, 95% CI 1.70 to 23.30) were independently associated with persistent opioid use.ConclusionOur study showed that 25% of patients with cervical cancer were still using opioids 6 months after radiation. History of substance abuse and depression or anxiety, all known risk factors for opioid misuse, were associated with persistent use. The goal in the disease-free survivor population should be opioid independence.

scholarly journals Magnitude and associated factors of VIA positive test results for cervical cancer screening among refugee women aged 25–49 years in North Ethiopia

BMC Cancer ◽  
2020 ◽  
Vol 20 (1) ◽  
Author(s):  
Gebretsadik Hailemariam ◽  
Hailay Gebreyesus ◽  
Tewolde Wubayehu ◽  
Tsgehana Gebregyorgis ◽  
Kidanemariam Gebrecherkos ◽  
...  
Keyword(s):  
Cervical Cancer ◽  
Cancer Screening ◽  
Associated Factors ◽  
Previous History ◽  
Test Results ◽  
Cervical Lesions ◽  
Sexually Transmitted ◽  
Refugee Women ◽  
History Of ◽  
Precancerous Cervical Lesions

Abstract Background Worldwide cervical cancer is the third most common malignancy in women. It usually arises from the cervical area which is susceptible to Human Papilloma virus induced malignancy changes. In low-resource setting visual inspection with acetic acid (VIA) is an alternative sensitive cervical screening method. Therefore the aim of this study was to assess the magnitude and associated factors of VIA positive test results for Cervical Cancer screening among Eritrean refugee women aged 25–49 years in northern Ethiopia refugee camps. Methods A community based cross-sectional study was conducted among 412 Eritrean refugee women aged 25–49 years from august 10 to September 25, 2018. Study subjects were selected by simple random sampling method. Data were collected using pretested structured questioner through Face-to-face interview and cervical examination. Data were coded and entered to Epi info software version 7 and then exported to Statistical package for Social Science (SPSS) version 21 for analysis. Bivariable and multivariable logistic regression analysis was made to test the association between the independent variables and the outcome variable. P-value of less than 0.05 with 95% CI was considered to declare statistical significance. Result In this study the magnitude of VIA positive precancerous cervical lesions was 9% (95% CI: 6.3–11.8%). Previous history of sexually transmitted infections (STI) [AOR (95%CI) = 2.84(1.07–7.53)] and presence of STI during cervical examination [AOR (95%CI) =3.97(1.75–9.00)] were found significantly associated with VIA positive precancerous cervical lesions. Conclusions In this study the magnitude of VIA positive precancerous cervical lesions was high. Previous history of sexually transmitted infections (STI) and presence of STI during cervical examination were found associated with VIA positive precancerous cervical lesions. Efforts such as early screening for sexually transmitted disease shall be done to prevent precancerous cervical lesions.

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