scholarly journals A study on cervical cancer screening using pap smear in urban area in state of Meghalaya, India

Author(s):  
Priti Mishra ◽  
Ragini Thapa ◽  
Arvind Kumar Dinkar

Background: Cancer cervix is fourth most common cancer in world second most common in India. The objective of the study is to identify abnormal pap smear cytology in women undergoing the test.Methods: This retrospective study conducted in 200 women attending gynae OPD of Military Hospital, Shillong, Meghalaya, India between January 2016 to December 2017. Pap smear test was done, and classification was done as per Bethesda system 2014.Results: 105 women had normal cytology findings and 23 had abnormal cytology.Conclusions: Cervical cancer is the most common cancer for which screening is done. If pap smear is done every 3 years as per the guidelines mortality due to cervical cancer can be reduced. Every woman should undergo pap test at least once in her life before the age of 45 years. Timely screening of preinvasive lesion allows prevention from invasive cervical cancer.


2021 ◽  
Vol 17 (2) ◽  
pp. 117-123
Author(s):  
Tika Kumari Gurung ◽  
Shree Prasad Adhikari ◽  
Ayushma Adhikari ◽  
Reecha Shrestha ◽  
Chum Maya Pun ◽  
...  

Abstract: Background: Cervical cancer is the fourth most common cancer in women with high mortality. Since it is a preventable cancer, screening for cervical cancer with Papanicolaou test (Pap Test) is considered as the stepping stone in its cure by detecting  at its premalignant state. The two methods of acquiring the sample for cytology are Conventional method and liquid based cytology. Methods:  The Pap test  results of the patients who visited the outpatient clinic of the Gynecologic Department of Gandaki Medical College and Teaching Hospital from January 2012 to December 2017 were reviewed and analyzed from the medical records. The findings of Pap test results were tabulated and categorized as per Bethesda system of classification (2001). Results:  A total of 2004 Pap tests were taken. All of the patients in the study were married with mean age of 39.7±10.3 years. A total of 1291(64.42%) Pap tests were normal or negative for intraepithelial lesion whereas 578(28.84%) were inflammatory smears while 37(1.85%) were inadequate for evaluation. There was a presence of low grade intraepithelial lesion in 4(0.2%)  and high grade intraepithelial lesion in 15(0.75%). Atypical squamous cell of undetermined significance (ASCUS) was noted in 11(0.55%) and frank malignancy was noted in 1(0.05%) of total Pap test samples. Conclusion: In a developing country like Nepal, Pap test is still the preferred cervical cancer screening tool. All women should undergo the screening test for cervical cancer with any feasible available test. Key words: Bethesda system; cervical cancer; HPV; Pap Test.



2021 ◽  
Vol 8 (16) ◽  
pp. 1009-1014
Author(s):  
Manjunath M.R ◽  
Sheetal Sheetal

BACKGROUND A long pathological process for investigation of precursor lesion squamous intraepithelial lesion (SIL) leads to invasive cervical cancer. This SIL can be detected much earlier before the lesion progresses to invasive cancer. For greater than fifty years, screening for cancer cervix was done by conventional scrape smears and stained by Papanicolaou [Pap] stain but conventional Pap smears (CPAP) have been reported to have low sensitivity. To overcome these drawbacks manual liquid-based cytology [MLBC] was introduced. The objective of this study was to screen females for cervical cancer using CPAP and MLBC techniques and compare the results of these techniques. METHODS Cervical cytology samples were obtained from 120 non-pregnant females through specialised Uprep cytobrush with a detachable head. Thus, obtained samples were first smeared onto a clean glass slide for CPAP smear, and the whole head to cytobrush was dropped into the specialised Uprep liquid preservative medium and processed by using Uprep Cytospin machine to obtain MLBC smears. Both the smears were stained by conventional Pap stain and reported according to 2014 Bethesda system. RESULTS In this study, the CPAP method had a greater number of unsatisfactory smears than that of MLBC method which was statistically significant. MLBC identified more number of intraepithelial lesions when compared to CPAP and MLBC had an increased detection rate [IDR] of 73.68 % over CPAP. CONCLUSIONS Analysis of our results showed that MLBC had more advantages over CPAP. Since the cost effective MLBC has an improved rate of detection of abnormal lesions, MLBC can be used as a routine technique for screening of cancer cervix in India. Also, MLBC offers an important advantage of performing both human papillomaviruses deoxyribonucleic acid (HPV DNA) test and cytological analysis on a single sample. KEYWORDS Cervical Cancer, Conventional Pap Smear, Manual Liquid Based Cytology, Human Papilloma Virus (HPV DNA), Bethesda System



2003 ◽  
Vol 13 (6) ◽  
pp. 827-833 ◽  
Author(s):  
P. Gichangi ◽  
B. Estambale ◽  
J. Bwayo ◽  
K. Rogo ◽  
S. Ojwang ◽  
...  

Invasive cervical cancer (ICC) is the leading cause of cancer-related death among women in developing countries. Population-based cytologic screening and early treatment does reduce morbidity and mortality associated with cervical cancer. Some of the factors related to the success of such a program include awareness about cervical cancer and its screening. The objective of this study was to assess knowledge and practice about cervical cancer and Pap smear testing among cervical cancer and noncancer patients using a structured questionnaire to obtain information. Fifty-one percent of the respondents were aware of cervical cancer while 32% knew about Pap smear testing. There were no significant differences in knowledge between cervical cancer and noncancer patients. Health care providers were the principal source of information about Pap testing (82%). Only 22% of all patients had had a Pap smear test in the past. Patients aware of cervical cancer were more likely to have had a Pap smear test in the past. The level of knowledge is low among ICC and noncancer patients. There is need to increase the level of knowledge and awareness about ICC and screening among Kenyan women to increase uptake of the currently available hospital screening facilities.



2006 ◽  
Vol 16 (3) ◽  
pp. 1063-1068 ◽  
Author(s):  
E. P. Gharoro ◽  
E. N. Ikeanyi

Papanicolaou (Pap) smear test is considered the best approach to reduce cervical cancer incidence worldwide. We surveyed 195 female health workers with structured questionnaires to identify factors that could influence the awareness and utilization of the Pap smear as a cervical cancer screening test. More than 65% of the respondents were aware of the disease, cervical cancer, and approximately 64% were aware of the Pap smear test. Seven three (39.7%) of the respondents had their sexual debut (coitarche) before the age of 20 years, while 109 (59.9%) have had multiple sexual partners. The modal number of sexual partners was 3, range 0–8. Pap smear awareness level significantly varied among the categories of the female health workers (P < 0.001). A minority of 14.1% have had a Pap test. There was a significant variation in utilization of Pap test across the various categories of the health workers (Pearson Chi-square 14.67, P < 0.05), and a significant correlation between Pap smear awareness and utilization (P < 0.001). The majority, 89%, believed that they were not at risk of developing cervical cancer. The self-reported utilization of Pap test among health workers was low. While there was a positive correlation between Pap test awareness and utilization, screening uptake was very poor due to a combination of inappropriate beliefs, misapprehension, and deficient knowledge. There is an urgent need for an aggressive awareness campaign and the provision of a screening program nationally.



2019 ◽  
Vol 9 (4) ◽  
pp. 280-283
Author(s):  
Mitra Modarres Gilani ◽  
Azam Sadat Mosavi ◽  
Setare Akhavan ◽  
Mehrangiz Zamani ◽  
Mohammad Ali Mohsenpour ◽  
...  

Objectives: Invasive cervical cancer is one of the most fatal genital cancers of women which can be detected by having Pap smear in precancerous stage. Various approaches can be taken for treating or preventing the progress of these precancerous lesions. The aim of this study was to investigate the cytopathological and colposcopic response of precancerous lesions to multivitamin, mineral (multi-mineral), and coenzyme Q10 supplements. Materials and Methods: The present randomized clinical trial was conducted on 120 participants with clinical complaints or abnormal Pap smear test results. The intervention and control groups received supplemental and placebo treatments, respectively, for 3 months after a primarily Pap smear test. The Pap smear test was also performed after the treatment and patients with abnormal results were screened by colposcopy. Data were analyzed by SPSS software and P-value less than 0.05 was considered significant. Results: The percentage of participants in the intervention and control groups were 40% and 28.3% in the age range of 20-29, 26.7% and 41.7% in the age range of 30–39, and finally 33.3% and 30% over 40 years of age, respectively (P=0.19). The percentage of normalization in Pap smear test result was 83.3% and 53.3% in the intervention and control groups, respectively (P<0.001). Conclusions: It was found that short-term usage of multi-mineral and Q10 supplements may decrease the risk of cervical cancer in women with abnormal Pap smear. However, studies with larger population and longer trial period are needed for further investigation.



2021 ◽  
Vol 18 (1) ◽  
Author(s):  
Sumarmi Sumarmi ◽  
Yu-Yun Hsu ◽  
Ya-Min Cheng ◽  
Shu-Hsin Lee

Abstract Purposes This study aimed to understand the influence of health beliefs, demographic factors, and health characteristics on the intention to undergo Pap smear testing among women in rural areas of Indonesia. Methods A descriptive cross-sectional study was conducted and 687 married women participated in the study. A convenience sampling was applied to recruit the participants from community health centres in a rural region in Indonesia. Self-reported data using the Health Beliefs Model Scale for Cervical Cancer and Pap Smear Test was collected to assess the health beliefs. Independent t-tests, simple logistic regressions, and a hierarchical logistic regression with 3 steps were run. Statistical significance for analysis was set at p < 0.05. Results The mean age of the participants was 42 years (SD = 8.4). Among the participants, 81% of the women had never undergone a Pap smear test, and 61% (n = 422) of the women reported a high intention of receiving a Pap smear test. Income and education Health beliefs regarding Pap smear testing were different between women who had low and high intentions to undergo Pap smear testing. Health beliefs, such as perceived benefits, severity, barriers to Pap smear testing, and health motivation for a Pap smear test were associated with the intention to undergo Pap smear testing among rural Indonesian women. Overall, the hierarchical multiple regression with 3 steps containing demographic, health characteristics, and health belief variables accounted for 31% variance of the intention to undergo Pap smear test among the Indonesian rural women. Conclusions Low screening rates of cervical cancer and high intentions to do the screening exist among rural Indonesian women. Health beliefs significantly affect the rural women’s intention of Pap smear testing in Indonesia.



2021 ◽  
Vol 11 (9) ◽  
pp. 4091
Author(s):  
Débora N. Diniz ◽  
Mariana T. Rezende ◽  
Andrea G. C. Bianchi ◽  
Claudia M. Carneiro ◽  
Daniela M. Ushizima ◽  
...  

Prevention of cervical cancer could be performed using Pap smear image analysis. This test screens pre-neoplastic changes in the cervical epithelial cells; accurate screening can reduce deaths caused by the disease. Pap smear test analysis is exhaustive and repetitive work performed visually by a cytopathologist. This article proposes a workload-reducing algorithm for cervical cancer detection based on analysis of cell nuclei features within Pap smear images. We investigate eight traditional machine learning methods to perform a hierarchical classification. We propose a hierarchical classification methodology for computer-aided screening of cell lesions, which can recommend fields of view from the microscopy image based on the nuclei detection of cervical cells. We evaluate the performance of several algorithms against the Herlev and CRIC databases, using a varying number of classes during image classification. Results indicate that the hierarchical classification performed best when using Random Forest as the key classifier, particularly when compared with decision trees, k-NN, and the Ridge methods.



2021 ◽  
Vol 1 (69) ◽  
pp. 6
Author(s):  
Gheorghe Cruciat ◽  
Iulia Popa ◽  
Suzana Mariam Chaikh-Sulaiman


Author(s):  
Wan Azani Mustafa ◽  
Low Zhe Wei ◽  
Khairul Shakir Ab Rahman

Cervical cancer is a common cancer that affects women around the world, and it is also the most common cancer in the developing countries. The cancer burden has increased due to several factors, such as population growth and ageing. In the early century, the systematization of cervical cancer cells takes some time to process manually, and the result that comes out is also inaccurate. This article presents a new nucleus segmentation on pap smear cell images based on structured analysis or morphological approach. Morphology is a broad set of image processing operations that process images based on shape, size and structure. This operation applies a structural element of the image to create an output image of the same size. The most basic of these operations are dilation and erosion. The results of the numerical analysis indicate that the proposed method achieved about 94.38% (sensitivity), 82.56% (specificity) and 93% (accuracy). Also, the resulting performance was compared to a few existing techniques such as Bradley Method, Nick Method and Sauvola Method. The results presented here may facilitate improvements in the detection method of the pap smear cell image to resolve the time-consuming issue and support better system performance to prevent low precision result of the Human Papilloma Virus (HPV) stages. The main impact of this paper is will help the doctor to identify the patient disease based on Pap smear analysis such as cervical cancer and increase the percentages of accuracy compared to the conventional method. Successful implementation of the nucleus detection techniques on Pap smear image can become a standard technique for the diagnosis of various microbiological infections such as Malaria and Tuberculosis.



2005 ◽  
Vol 16 (3) ◽  
pp. 233-236 ◽  
Author(s):  
L C Chingang ◽  
U Bischof ◽  
G Andall-Brereton ◽  
O Razum

In many middle-income countries with a high incidence of cervical cancer, organized screening programmes with the Pap test are being planned. We assessed the knowledge of, and attitudes towards, cervical screening among 63 doctors and 102 randomly selected community members in Trinidad where screening is still opportunistic. Doctors were well informed about cervical cancer, but not all knew the approximate specificity of the Pap test. Many did not routinely discuss the benefits and disadvantages of screening with their clients. Most women had heard of the Pap test, but only 56% knew its purpose; 25% would not participate in screening, stating reasons such as being in menopause or not having symptoms. More information about the aim of screening and the purpose of the Pap test must be communicated. Doctors need to keep their knowledge on screening up-to-date, and offer counselling that helps women to make an informed decision whether or not to participate in screening.



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