scholarly journals Prevalence of Urinary Tract Infection and Antimicrobial Susceptibility among Diabetic Patients with Controlled and Uncontrolled Glycemia in Kuwait

2016 ◽  
Vol 2016 ◽  
pp. 1-7 ◽  
Author(s):  
May Sewify ◽  
Shinu Nair ◽  
Samia Warsame ◽  
Mohamed Murad ◽  
Asma Alhubail ◽  
...  

Diabetic patients have higher risk of urinary tract infection (UTI). In the present study, we investigated the impact of glycemic control in diabetic patients on UTI prevalence, type of strains, and their antimicrobial drugs susceptibility. This study was conducted on urine samples from 722 adult diabetic patients from which 252 (35%) samples were positive for uropathogens. Most UTI cases occurred in the uncontrolled glycemic group (197 patients) versus 55 patients with controlled glycemia. Higher glycemic levels were measured in uncontrolled glycemia group (HbA1c = 8.3 ± 1.5 and 5.4 ± 0.4, resp.,P<0.0001). Females showed much higher prevalence of UTI than males in both glycemic groups (88.5% and 11.5%, resp.,P<0.0001). In the uncontrolled glycemia group 90.9% of the UTI cases happened at ages above 40 years and a clear correlation was obtained between patient age ranges and number of UTI cases (r=0.94;P=0.017), whereas in the group with controlled glycemia no trend was observed.Escherichia coliwas the predominant uropathogen followed byKlebsiella pneumoniaeand they were together involved in 76.2% of UTI cases. Those species were similarly present in both diabetic groups and displayed comparable antibiotic resistance pattern. These results highlight the importance of controlling glycemia in diabetic patients to reduce the UTI regardless of age and gender.

Author(s):  
HARIKRISHNAN S. ◽  
ROSY VENNILA ◽  
R. MONICA

Objective: Urinary tract infection (UTI) is one of the most common infections observed in diabetic patients. This study is aimed at identifying the organisms with their anti-bacterial resistance pattern. Methods: A total of 400 diabetic patients over a period of nine months presenting with symptom s of urinary tract infection were taken for the study. Their urine were cultured and an antibiogram done. Results: E. coli, Klebsiella and Enterococci were the commonest organism found. It was found that E. coli, which was the commonest organism E. Coli was sensitive to Norfloxacin and resistant to Ciprofloxacin. Conclusion: Empirical treatment with ciprofloxacin, Which is considered the drug of choice, will lead to failure of treatment.


Heliyon ◽  
2020 ◽  
Vol 6 (6) ◽  
pp. e04161 ◽  
Author(s):  
Ahmed Hossain ◽  
Saeem Arafat Hossain ◽  
Aneeka Nawar Fatema ◽  
Abrar Wahab ◽  
Mohammad Morshad Alam ◽  
...  

Author(s):  
Sarita Otta ◽  
Bichitrananda Swain ◽  
Priyadarshini Bhoi

Background: Diabetes mellitus is a predisposing condition to different infections especially the complicated urinary tract infection (UTI). The susceptibility pattern of organisms in diabetics is different from their counterparts. So, there is always a dilemma while administering empirical regimen for UTI in diabetics. The study aims to find the common organisms implicated in the UTI in diabetic patients and their sensitivity pattern.Methods: Properly collected urine specimen from all the diabetic (cases) and non-diabetic (controls) patients included in this study was processed. Sensitivity pattern and extended spectrum beta lactamase (ESBL) production for the isolated uropathogens was noted.Results: E. coli was the most common organism isolated from both 68 cases and 85 controls in this study. Most of UTI patients with diabetes, 46 (67.7 %) had uncontrolled blood sugar level. Diabetics are more prone for catheter associated UTI (CAUTI) and fungal UTI. Most of the E coli and Atypical E coli isolated were ESBL positive for the diabetic patients (60.5%) than that for the non-diabetics (40.4%). Antimicrobial resistance pattern was similar in both the groups with maximum patients’ sensitivity to tigecycline, colistin, fosphomycin and least susceptibility to cefixime. Both E. coli and Klebsiella also showed high resistance to the fluoroquinolones.Conclusions: E. coli is the predominant uropathogen for both the diabetic & non-diabetic cases. But diabetics are more prone to get ESBL positive UTI. CAUTI and the fungal UTI are more common in diabetics. Diabetic condition does not affect the antimicrobial resistance pattern of uropathogens. But their rising resistance to fluoroquinolones, cephalosporins is a matter of concern while prescribing empiric regimen.


2013 ◽  
Vol 35 (2) ◽  
pp. 93-98 ◽  
Author(s):  
Denise Swei Lo ◽  
Huei Hsin Shieh ◽  
Selma Lopes Betta Ragazzi ◽  
Vera Hermina Kalika Koch ◽  
Marina Baquerizo Martinez ◽  
...  

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