scholarly journals Mediastinal Mature Teratoma Revealed by Empyema

2016 ◽  
Vol 2016 ◽  
pp. 1-4 ◽  
Author(s):  
Mohammed Raoufi ◽  
Laila Herrak ◽  
Anas Benali ◽  
Leila Achaachi ◽  
Mustapha El Ftouh ◽  
...  
Keyword(s):  
Chest Pain ◽  
Mature Teratoma ◽  
Germ Cell Tumors ◽  
Left Lung ◽  
Needle Aspiration ◽  
Anterior Mediastinum ◽  
Cystic Tumor ◽  
Left Hemithorax ◽  
Adequate Treatment ◽  
Mediastinal Teratoma

Teratomas are germ cell tumors, manifested with a great variety of clinical features; the most common extragonadal site is the anterior mediastinum. In this case, we report the patient with a large mature mediastinal teratoma with several components of ectodermal and endothermal epithelium. A 24-year-old female patient presented with history of persistent chest pain and progressively aggravating dyspnea for the previous 3 months. A chest X-ray showed a large opacity of the entire left hemithorax. Transcutaneous needle aspiration revealed a purulent fluid. The tube thoracostomy was introduced and the effusion was evacuated. Some weeks later, patient was seen in emergency for persistent cough and lateral chest pain. CT scan revealed a mass of the left hemithorax. The mass showed heterogeneous density, without compressing mediastinum great vessels and left hilar structures. Lipase value was elevated in needle aspiration. The patient underwent a total resection of the mediastinum mass via a left posterolateral thoracotomy. Microscopy revealed a mature teratoma with cystic structures. The patient subsequently made a full recovery. This case provide benign mediastinal teratoma with total atelectasis of left lung and elevated lipase value in needle transcutaneous aspiration; this event is explained by pancreatic component in the cystic tumor. Total removal of the tumor is adequate treatment for this type of teratoma and the prognosis is excellent.

scholarly journals Anterior Mediastinal Teratoma- A Rare Variety

Pulse ◽  
2018 ◽  
Vol 10 (1) ◽  
pp. 52-56
Author(s):  
SMAZN Palash ◽  
MD Hossain ◽  
TMNS Khan ◽  
T Meher ◽  
MK Hasan ◽  
...  
Keyword(s):  
Germ Cell Tumors ◽  
Left Lung ◽  
Large Mass ◽  
Anterior Mediastinum ◽  
Mediastinal Teratoma ◽  
Clamshell Thoracotomy ◽  
Great Vessels ◽  
Operative Recovery ◽  
Benign Teratoma

Anterior mediastinal teratomas are rare germ cell tumors. We report a case of such rare tumor in a 16 years old boy who presented with sudden severe right sided abdominal pain which radiating to chest for one day. CT scan of the chest was suggestive of anterior mediastinal teratoma. Patient underwent Clamshell thoracotomy. Peroperatively a large mass was found in the anterior mediastinum containing huge amount of sebum like material. It was adherent to mediastinal surface of right & left lung, pericardium and great vessels (SVC, Aorta). The tumor and was resected out except part of its posterior surface which was adherent to pericardium and great vessels and was left in situ. He had a smooth & uneventful post-operative recovery. Histopathology reported as mature (benign) teratoma with no evidence of malignancy.Pulse Vol.10 January-December 2017 p.52-56

scholarly journals Mature teratoma with aspergilloma

2019 ◽  
Vol 23 (3) ◽  
pp. 119-122
Author(s):  
Abebe Bezabih ◽  
Asfaw Atnafu
Keyword(s):  
Surgical Treatment ◽  
Germ Cell ◽  
Literature Search ◽  
English Literature ◽  
Mature Teratoma ◽  
Germ Cell Tumors ◽  
Rare Presentation ◽  
Mediastinal Teratoma ◽  
Intrathoracic Mass

Mediastinal mature teratomas are benign germ cell tumors which rarely involve the lung, but when they involve the lung they can cavitate. Aspergilloma developing in a mature teratoma is extremely rare, and according to our English literature search, there is only one previously reported case. We report a 21-year-old female who presented with cough and foul-smelling sputum. investigations revealed an intrathoracic mass, which intraoperatively and upon subsequent histological exam was found to be a mature mediastinal teratoma involving the lung and associated with an aspergilloma. Reporting our case will add to the understanding of this rare presentation of mediastinal mature teratomas. Keywords: mature teratoma; aspergilloma; surgical treatment 

scholarly journals NI-11 Clinical significance of intracystic diffusion hyperintensity lesions remaining after treatment of intracranial germ cell tumor

2020 ◽  
Vol 2 (Supplement_3) ◽  
pp. ii14-ii14
Author(s):  
Motoki Takano ◽  
Takeshi Takayasu ◽  
Ushio Yonezawa ◽  
Akira Taguchi ◽  
Kazuhiko Sugiyama ◽  
...  
Keyword(s):  
Germ Cell ◽  
Clinical Significance ◽  
Cyst Wall ◽  
High Intensity ◽  
Mature Teratoma ◽  
Germ Cell Tumors ◽  
Residual Tumor ◽  
Cystic Tumor ◽  
Intracranial Germ Cell Tumor ◽  
Intensity Lesion

Abstract Background and purpose: About 30% of intracranial germ cell tumors are mixed germ cell tumors and teratomas are often found as those components. Intense chemoradiotherapy is performed according to the malignancy of the histopathology, but high-intensity lesion inside the cystic tumor on diffusion weighted imaging (DWI) sometimes remains after completion of the chemoradiotherapy. In this study, we examined the clinical significance of the DWI high-intensity lesion remaining in the cyst. METHODS: Five patients after initial chemoradiotherapy were resected residual tumor by craniotomy at our hospital from 2009 to 2019. Preoperative gadolinium-enhanced MRI defined the non-contrast-enhanced part of the tumor as intracystic, and DWI intensity was classified by its look as low-intensity, equal-intensity, and high-intensity compared to the cortex of the same slice. DWI signals in the solid area, cyst wall, and cyst were evaluated. Results: All cases were mature teratoma in histopathology, and no other tumor components were observed. On DWI, the cyst wall and solid part were visualized with low signal. High-intensity lesions and equal-intensity lesions in the cyst cavity were found in 3 and 1 cases, respectively. In these cases, pathological findings revealed a keratin-like substance in the cyst. Discussion: The intracystic high and equal intensity lesions on DWI removed after completion of chemoradiotherapy are considered to reflect the keratin-like component of mature teratoma. If DWI- high intensity and equal intensity lesions remain in the cyst of the tumor after the completion of chemoradiotherapy, tumor shrinkage cannot be expected even if the chemotherapy is strengthened. In such cases, we should consider to removing them by surgery. Conclusion: When DWI high and equal intensity lesions are found in the cysts of tumors remaining after chemoradiotherapy for intracranial germ tumors, it is possible that mature teratoma remains.

scholarly journals Fetal Presentation of Mediastinal Immature Teratoma: Ultrasound, Autopsy and Cytogenetic Findings

Diagnostics ◽  
2021 ◽  
Vol 11 (9) ◽  
pp. 1543
Author(s):  
Maria Paola Bonasoni ◽  
Giuseppina Comitini ◽  
Veronica Barbieri ◽  
Andrea Palicelli ◽  
Nunzio Salfi ◽  
...  
Keyword(s):  
Heart Failure ◽  
Fetal Monitoring ◽  
Surgical Excision ◽  
Fetal Outcome ◽  
Anterior Mediastinum ◽  
Therapeutic Strategies ◽  
Cystic Mass ◽  
Immature Teratoma ◽  
Adequate Treatment ◽  
Mediastinal Teratoma

Teratomas are the most common congenital tumors, occurring along the midline or paraxial sites, or uncommonly, the mediastinum. Teratomas are classified as mature, containing only differentiated tissues from the three germinal layers; and immature, which also present with neuroectodermal elements, ependymal rosettes, and immature mesenchyme. Herein, we describe a new case of fetal mediastinal immature teratoma detected at 21 weeks of gestational age (wga) + 1 day with thorough cytogenetic analysis. Ultrasound (US) showed a solid and cystic mass located in the anterior mediastinum, measuring 1.8 × 1.3 cm with no signs of hydrops. At 22 wga, US showed a mass of 2.4 cm in diameter and moderate pericardial effusions. Although the prenatal risks and available therapeutic strategies were explained to the parents, they opted for termination of pregnancy. Histology showed an immature teratoma, Norris grade 2. Karyotype on the fetus and tumor exhibited a chromosomal asset of 46,XX. The fetal outcome in the case of mediastinal teratoma relies on the development of hydrops due to mass compression of vessels and heart failure. Prenatal US diagnosis and close fetal monitoring are paramount in planning adequate treatment, such as in utero surgery, ex utero intrapartum therapy (EXIT) procedure, and surgical excision after birth.

scholarly journals Ruptured mediastinal mature teratoma causing severe mediastinitis: report of a surgically resected case and a literature review

2021 ◽  
Vol 7 (1) ◽  
Author(s):  
Eri Nakajima ◽  
Yujin Kudo ◽  
Sachio Maehara ◽  
Hideyuki Furumoto ◽  
Jun Matsubayashi ◽  
...  
Keyword(s):  
Literature Review ◽  
Surgical Resection ◽  
Mature Teratoma ◽  
Median Sternotomy ◽  
Surgical Margin ◽  
Emergency Admission ◽  
Anterior Mediastinum ◽  
Cystic Mass ◽  
Mediastinal Teratoma ◽  
The Right

Abstract Background Mediastinal teratomas occasionally rupture into the thoracic cavity, which induces mediastinitis or various other severe complications. Surgical treatment is crucial for ruptured teratomas; however, few literature reviews to date have addressed the characteristics of ruptured mediastinal teratomas. Case presentation We report a 29-year-old woman with severe mediastinitis owing to a mediastinal mature teratoma that ruptured into the mediastinum and right pleural cavity. Surgical resection by median sternotomy was performed within 24 hours after emergency admission. Intraoperative findings demonstrated the ruptured wall of the tumor with exposure of its white contents, which appeared similar to skin and fat, and necrotic tissue in the anterior mediastinum. The tumor was adhered to the right upper lobe, the ascending aorta, and pericardium. Owing to the severe adhesion of the tumor caused by inflammation in the surrounding tissues, a small portion of the tumor could not be removed, and hence complete resection with a sufficient surgical margin was not achieved. Pathologically, the tumor consisted of a solid mass and a cystic mass with severe adhesion to the resected portion of the lung, which included skin and lipid tissue. The tumor was concluded to be a mature teratoma as neither an immature component nor malignant transformation was observed. The patient had an uneventful postoperative course. Conclusions To our knowledge, this is the report of successful surgical resection of a ruptured mediastinal teratoma causing severe mediastinitis, with the first literature review of ruptured mediastinal teratomas. We also discuss relevant findings from reports in the literature.

scholarly journals CT features of mature teratoma in the mediastinum of two young adults—a report of two cases

2020 ◽  
Vol 51 (1) ◽  
Author(s):  
Naqibullah Foladi ◽  
Farhad Farzam ◽  
Najibullah Rahil ◽  
Mer Mahmood Shah Hoshang
Keyword(s):  
Germ Cell ◽  
Mature Teratoma ◽  
Germ Cell Tumors ◽  
Anterior Mediastinum ◽  
Good Prognosis ◽  
Chest Ct ◽  
Case Presentation ◽  
Superior Mediastinum ◽  
Chest Ct Scan ◽  
Ct Features

Abstract Background Germ cell tumors prefer gonadal regions, but they can be expected in extragonadal sites such as the anterior mediastinum, which is the commonly involved region after gonads. Amongst germ cell tumors, teratomas are the rarer subtypes which develop in the anterior mediastinum. Case presentation The authors present two adult patients, a male and a female, both complaining of chronic chest pain and cough. Chest CT scans were performed revealing characteristic CT features of mature teratomas in the anterior mediastinum which were extending to the superior mediastinum in both patients. Conclusion Germ cell tumors are involving the mediastinum; however, amongst all germ cell tumors, teratoma is the least common type arising in the mediastinum, and a chest CT scan considered the imaging investigation of choice. Surgery is the best option and patients may have a very good prognosis.

scholarly journals An uncommon case of anterior mediastinal teratoma

2020 ◽  
Vol 7 (11) ◽  
pp. 3843
Author(s):  
Soorya C. Sekar ◽  
Rohan A. Maydeo ◽  
Navin Kasliwal ◽  
Anirudha Mandhane
Keyword(s):  
Germ Cell ◽  
Main Bronchus ◽  
Mature Teratoma ◽  
Germ Cell Tumors ◽  
Interesting Case ◽  
Computed Tomographic ◽  
Mediastinal Teratoma ◽  
Extrinsic Compression ◽  
Gradual Onset ◽  
Cell Layers

Germ cell tumors (GCT) are commonly seen in both children and young adults. Teratomas are a form of GCT and histologically contain tissues derived from all three germ cell layers. These tumors can exhibit malignant behaviour, hence should be diagnosed and treated as early as possible. So, hereby present a case of 18-year-old female who presented with complaints of fever and cough with gradual onset from 20 days. A chest X-ray revealed growth in the left side of the chest. A high-resolution computed tomographic (HRCT) scan of the chest showed a large well-defined hypodense lesion in the left hilar region. Bronchoscopy showed extrinsic compression in the left main bronchus. The patient underwent anterolateral thoracotomy to remove a 9×9 cm mass lying in the mediastinum resting on pericardium. The histopathology specimen turned out to be a mature teratoma. This interesting case is described with its incidence, diagnosis and management protocols for the mediastinal teratoma.

scholarly journals Primary seminoma arising in the posterior mediastinum: a diagnostic challenge

2021 ◽  
Author(s):  
Sara Parini ◽  
Paolo Spina ◽  
Esther Papalia ◽  
Renzo Boldorini ◽  
Michele Abruzzese ◽  
...  
Keyword(s):  
Incidental Finding ◽  
Germ Cell Tumors ◽  
Surgical Excision ◽  
Needle Aspiration ◽  
Posterior Mediastinum ◽  
Anterior Mediastinum ◽  
Tracer Uptake ◽  
Pathology Report ◽  
Diagnostic Challenge ◽  
Complete Excision

Primary mediastinal germ cell tumors are a rare finding, and one third of them are seminomas. Seminomas are found in the anterior mediastinum, whereas they are extremely rare within the posterior compartment. Most clinicians would not consider a primary seminoma in the differential diagnosis of a posterior mediastinal mass, as only two cases have been reported in literature. Here we present the case of a 57-year-old male with a primary seminoma arising in the left posterior mediastinum. He was asymptomatic and the mass was an incidental finding. Positron emission tomography (PET) revealed a small area with an avid tracer uptake. Transthoracic needle aspiration led to a non-diagnostic result. Due to the strong suspect of malignancy, a surgical excision was chosen to obtain a diagnosis. He underwent complete excision, and pathology report demonstrated a mediastinal seminoma. Subsequent further staging did not reveal any other location of the disease. Given the complete excision of the primary tumor, active surveillance was the treatment of choice. The patient is free of disease 48 months after diagnosis.

scholarly journals Mediastinal Teratoma with Neuroendocrine Features in 34-Year-Old Male with Syncope

2015 ◽  
Vol 2015 ◽  
pp. 1-5
Author(s):  
Peter A. Andrawes ◽  
Masood A. Shariff ◽  
Qing Chang ◽  
Fanyi Kong ◽  
Frank M. Rosell
Keyword(s):  
Germ Cell ◽  
Surgical Resection ◽  
Neuroendocrine Tumors ◽  
Germ Cell Tumor ◽  
Mediastinal Mass ◽  
Mature Teratoma ◽  
Germ Cell Tumors ◽  
Cell Tumor ◽  
Mediastinal Teratoma

Neuroendocrine tumors that arise in an extragonadal teratoma are extremely rare. Somatic-type malignancy, defined as any sarcoma, carcinoma, leukemia, or lymphoma developing in a germ cell tumor, occurs in approximately 2% of all germ cell tumors. Our case represents a mediastinal mass that was incidentally found in a patient with syncope. Surgical resection confirmed mature teratoma with neuroendocrine features.

scholarly journals Late presentation of unilateral lung agenesis in adulthood

2021 ◽  
Vol 52 (1) ◽  
Author(s):  
Arshed Hussain Parry ◽  
Mujahed Abdulsattar Ibrahim Raheem ◽  
Hussam Hassan Ismail ◽  
Osama Sharaf
Keyword(s):  
Main Bronchus ◽  
Left Lung ◽  
Left Hemithorax ◽  
Late Adulthood ◽  
Pulmonary Agenesis ◽  
Opaque Hemithorax ◽  
Dismal Prognosis ◽  
Mediastinal Shift ◽  
Lung Agenesis ◽  
Unilateral Pulmonary Agenesis

Abstract Background Pulmonary agenesis is a rare congenital anomaly with a reported prevalence of about 1 in 100,000 births. It may be bilateral or unilateral. Among the unilateral form, left lung agenesis is more common (70%); however, it is the right lung agenesis which carries a dismal prognosis due to the frequent association with a gamut of other congenital anomalies and greater degree of mediastinal shift leading to tracheo-bronchial and vascular distortion. The patients of unilateral pulmonary agenesis usually present in infancy or early childhood. Presentation in late adulthood as seen in our patient is rare. We present a case of left pulmonary agenesis that was diagnosed in 4th decade of life. Case presentation A 36-year-old male presented with gradually progressive exertional dyspnea of 1 month duration. Clinical examination revealed tachycardia and tachypnea. Chest radiograph showed opaque left hemithorax with ipsilateral mediastinal shift. Computed tomography clinched the diagnosis by demonstrating absence of left main bronchus, lung and left pulmonary artery with shift of heart, and great mediastinal vessels into left hemithorax. The patient was managed conservatively and discharged with attachment to out-patient department for regular follow-up. Conclusion Presentation of unilateral lung agenesis in late adulthood, as seen in the present case is extremely rare. This case report highlights that, a rare condition like unilateral pulmonary agenesis, should be considered in the list of differentials in an adult presenting with opaque hemithorax with ipsilateral mediastinal shift on radiography.

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