scholarly journals Feasibility of Radial Endobronchial Ultrasound-Guided Bronchoscopic Cryobiopsy without Fluoroscopy for Lung Parenchymal Lesions

2017 ◽  
Vol 2017 ◽  
pp. 1-5 ◽  
Author(s):  
Chih-Hao Chang ◽  
Chung-Shu Lee ◽  
Shih-Hong Li ◽  
Fu-Tsai Chung ◽  
Chih-Wei Wang ◽  
...  

Background. Cryobiopsy is used to biopsy peripheral lung lesions through flexible bronchoscopy with fluoroscopic guidance. However, fluoroscopy is not available at some institutions. This study evaluated the feasibility of radial endobronchial ultrasound-guided bronchoscopic cryobiopsy without fluoroscopy. Methods. This retrospective study was conducted at Chang Gung Memorial Hospital, Linkou branch, in Taiwan. This study enrolled patients who received bronchoscopy examinations with cryotechnology between July 2014 and June 2016. The data were collected through medical chart review. Results. During the study period, 101 patients underwent bronchoscopy examinations with cryotechnology. Ninety patients with endobronchial tumors were excluded from this study. Eleven patients who underwent radial endobronchial ultrasound-guided bronchoscopic cryobiopsy for lung parenchymal lesions were enrolled into this study. The mean age was 61.1 ± 13.8 years. Five patients were men, and the other six were women. The number of cryobiopsies ranged from 1 to 3. In the histological biopsies, the mean specimen diameter was 0.53 ± 0.23 cm, and the mean biopsy area was 0.20 ± 0.19 cm2. Nine of 11 patients had pathological diagnoses. No complications, including pneumothorax, respiratory failure, or major bleeding, were recorded after the procedure. Conclusions. Endobronchial ultrasound is used to ensure biopsy location, and endobronchial ultrasound-guided cryobiopsy is a feasible technique to biopsy peripheral lung lesions in selected cases at institutions without fluoroscopy equipment. This study provided some rationale for further studies examining the impact of fluoroscopy.

Respiration ◽  
2021 ◽  
pp. 1-7
Author(s):  
Jaemin Lee ◽  
Changhwan Kim ◽  
Hee Yun Seol ◽  
Hyeon Sung Chung ◽  
Jeongha Mok ◽  
...  

<b><i>Background:</i></b> Radial probe endobronchial ultrasound-guided transbronchial lung biopsy (RP-EBUS-TBLB) is widely used for diagnosis of peripheral lung lesions (PLLs). To date, there have been no reports regarding the clinical outcomes of RP-EBUS-TBLB for PLLs in patients with idiopathic pulmonary fibrosis (IPF). <b><i>Objectives:</i></b> This study was performed between October 2017 and December 2019 to identify the safety and diagnostic performance of RP-EBUS-TBLB in IPF patients. <b><i>Methods:</i></b> Patients were divided into the usual interstitial pneumonia (UIP) group (<i>n</i> = 39, 4%), the probable UIP group (<i>n</i> = 12, 1%), and the noninterstitial lung disease (non-ILD) group (<i>n</i> = 903, 95%). <b><i>Results:</i></b> The diagnostic yield was significantly lower in the UIP group than in the non-ILD group (62% vs. 76%; <i>p</i> = 0.042), but there were no significant differences between the UIP and probable UIP groups (62% vs. 83%; <i>p</i> = 0.293) or the probable UIP and non-ILD groups (83% vs. 76%; <i>p</i> = 0.741). Multivariate logistic analysis showed that the mean diameter of PLLs, positive bronchus sign on CT, and “within the lesion” status on EBUS were independently associated with success of the procedure. Especially, the presence of the UIP pattern on CT (OR, 0.385; 95% CI: 0.172–0.863; <i>p</i> = 0.020) was independently associated with failed diagnosis. Among patients with UIP, “within the lesion” status on EBUS (OR, 25.432; 95% CI: 2.321–278.666; <i>p</i> = 0.008) was shown to be a factor contributing to a successful diagnosis. Overall, there were no significant differences in complication rates among the 3 study groups. <b><i>Conclusion:</i></b> RP-EBUS-TBLB can be performed safely with an acceptable diagnostic yield, even in patients with IPF.


Lung Cancer ◽  
2011 ◽  
Vol 74 (2) ◽  
pp. 219-225 ◽  
Author(s):  
Kjetil Roth ◽  
Tomas Mikal Eagan ◽  
Alf Henrik Andreassen ◽  
Friedemann Leh ◽  
Jon Andrew Hardie

2019 ◽  
Vol 14 (10) ◽  
pp. S753
Author(s):  
S. Baeza Mena ◽  
M. Torky ◽  
C. Centeno Clemente ◽  
R. Tazi Mezalek ◽  
I. García Olivé ◽  
...  

Author(s):  
Mohamed Torky ◽  
Wafaa S. Elshimy ◽  
Mohamed AE. Ragab ◽  
Ghada A. Attia ◽  
Raquel Lopez ◽  
...  

PLoS ONE ◽  
2012 ◽  
Vol 7 (11) ◽  
pp. e49125 ◽  
Author(s):  
Chun-Ta Huang ◽  
Sheng-Yuan Ruan ◽  
Wei-Yu Liao ◽  
Yao-Wen Kuo ◽  
Chi-Ying Lin ◽  
...  

2014 ◽  
Vol 2014 ◽  
pp. 1-4 ◽  
Author(s):  
Hyung-Sup Shim ◽  
Dong-Hwi Kim ◽  
Ho Kwon ◽  
Sung-No Jung

Abdominal pocketing is one of the most useful methods in salvation of compromised replanted fingertips. Abdominal pocketing has generally been performed in the ipsilateral lower abdominal quadrant, but we have also performed contralateral pocketing at our institute. To determine which approach is more beneficial, a total of 40 patients underwent an abdominal pocketing procedure in either the ipsilateral or contralateral lower abdominal quadrant after fingertip replantation. Dates of abdominal pocketing after initial replantation, detachment after abdominal pocketing, range of motion (ROM) before abdominal pocketing, and sequential ROM after the detachment operation and date of full ROM recovery and Disabilities of Arm, Shoulder, and Hand questionnaire (DASH) score were recorded through medical chart review. Mean detachment date, mean abduction of shoulder after the detachment operation, and mean days to return to full ROM were not significantly different between the ipsilateral and contralateral pocketing groups. However, the mean DASH score was significantly lower in the contralateral group than the ipsilateral group. There were also fewer postoperative wound complications in the contralateral group than in the ipsilateral group. We, therefore, recommend contralateral abdominal pocketing rather than ipsilateral abdominal pocketing to increase patient comfort and reduce pain and complications.


2018 ◽  
Vol 62 (5-6) ◽  
pp. 380-385 ◽  
Author(s):  
Pietro Gianella ◽  
Paola M. Soccal ◽  
Jérôme Plojoux ◽  
Isabelle Frésard ◽  
Jean-Claude Pache ◽  
...  

Background: Endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) is an accurate procedure to sample mediastinal tissue. Rapid on-site cytologic evaluation (ROSE) has been advocated to improve the performance of this procedure, but its benefit remains controversial. Our objective is to assess the utility of ROSE for EBUS-TBNA diagnostic accuracy among unselected patients. Methods: We prospectively collected data from all consecutive EBUS-TBNA procedures performed between 2008 and 2014. ROSE was introduced since 2011 in our daily practice. The accuracy of EBUS-TBNA with and without ROSE was compared in a univariate and multivariate model accounting for confounding factors. The impact of ROSE was then analyzed according to the etiology and size of the lesions. Results: Among 348 EBUS-TBNA procedures analyzed, 213 were performed with ROSE. The overall accuracy tended to be better with ROSE than without (90.6 vs. 84.4%; p = 0.082). After adjustment in a multivariate model, the benefit of ROSE still did not reach statistical significance (adjusted odds ratio 1.86; 95% confidence interval 0.79–4.41). Similar results were obtained in subgroups of patients with malignant disease or sarcoidosis. The size of the lesion did not influence the impact of ROSE on accuracy. Conclusions: ROSE was associated with a moderate increase in the accuracy of EBUS-TBNA, but the difference was not statistically significant. The same effect of ROSE was observed in malignant and nonmalignant lesions and this effect was not influenced by the lesion’s size.


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